Gene

KWMTBOMO13033

Pre Gene Modal

BGIBMGA000422

Annotation

elongation_of_very_long_chain_fatty_acids_protein_AAEL008004_[Papilio_xuthus]

Location

Bomo_Chr22(-):6782052-6820121      View in EpiBrowser

Full name

Elongation of very long chain fatty acids protein      

Alternative Name

Very-long-chain 3-oxoacyl-CoA synthase

Location in the cell

PlasmaMembrane   Reliability : 4.722

CDS

ATGGACAGCAGGGGCGATCCTCGGGTGAAAGACTGGCCGATGATGTCATCGCCGTGGCCAACCCTAGCCGCGTGCGTGTGCTACGCATACTGCGCGAAGGAGCTTGGCCCCAAACTTATGGCCAATCGAAAACCATTCGAACTTCGAAATATTCTCGTCGTTTACAACATGGCTCAGACTATCTTCAGCGCCTGGATATTCTACGAGTATTTGATGAGCGGATGGTGGGGCCACTATGACTTTAGGTGTCAACTGGTAGATTACTCTCGGAGTCCAATGGCCATGAGGATGGCGAACACGTGTTGGTGGTACTACTTCAGCAAGTTCACAGAATTTATGGACACGCTTTTCTTTGTGCTACGGAAGAAGAACGAGCACGTGTCCACGTTGCATGTGATACATCACGGGATCATGCCGATGTCTGTTTGGTTCGGACTTAAATTCGCGCCGGGTGGTCACAGCACTTTCTTCGCTCTGCTCAACACGTTCGTTCACATCGTAATGTACTTTTACTACATGGTGGCTGCCATGGGTCCTAAGTATCAGAAGTATATCTGGTGGAAGAAATACCTCACAGCCTTCCAGATGGTTCAGTTCGTATTGATCTTTAGTCATCAACTCCAAGTCCTCTTCAGGCCGTCGTGTCAATACCCTCGTGTCTTCGTCTACTGGATCGCGATGCACGGCTTCTTATTCTTGTTCCTCTTCAGCGATTTCTACAAAGCGAGGTACACAACCGCCGAGAGGAAATCGAAGGCTCAGAACGGACTTTGTATGGCGGTGATGGACGACAGCTCGAGTTCGCTGAACGGCAGGAACGGCTACAAGCAGGAGATGGGGTCGGAGGTGCCCAGTTCGTACGCCTCGTCCGGGGCGGACGCGTTCGTGCGTCGGAGACCGCTCTCATAG

Protein

MDSRGDPRVKDWPMMSSPWPTLAACVCYAYCAKELGPKLMANRKPFELRNILVVYNMAQTIFSAWIFYEYLMSGWWGHYDFRCQLVDYSRSPMAMRMANTCWWYYFSKFTEFMDTLFFVLRKKNEHVSTLHVIHHGIMPMSVWFGLKFAPGGHSTFFALLNTFVHIVMYFYYMVAAMGPKYQKYIWWKKYLTAFQMVQFVLIFSHQLQVLFRPSCQYPRVFVYWIAMHGFLFLFLFSDFYKARYTTAERKSKAQNGLCMAVMDDSSSSLNGRNGYKQEMGSEVPSSYASSGADAFVRRRPLS

Catalytic Activity

a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA

Similarity

Belongs to the ELO family.

Uniprot

H9IT43   A0A2W1BVK9   B2DBH6   A0A194R1L2   S4P8U6   A0A1E1WBM2   + More
A0A212EXD6   A0A224XG77   A0A0V0G986   A0A023F5B4   A0A069DSG8   A0A0P4VQ12   A0A1B6D8X5   A0A290Y213   A0A1B6INS9   A0A1B6L1U0   D6X365   A0A1B6FFP4   A0A0K8TP99   A0A1B6GMU5   A0A1I8M7X8   A0A0L7RD69   A0A3Q8FM02   A0A0K8VMK5   A0A088AIA2   B3M2T7   A0A034VI44   B4M0X5   A0A1L8DY78   A0A3B0KWA1   A0A026WWA2   B4I3P6   B4KA49   A0A1B0A8T5   B3P216   J9K2C4   E1ZZH1   A0A336KQL3   A0A195EEV2   A0A2H8TI43   Q295H0   B4PTT6   A0A0A1WVQ5   A0A195AV43   A0A195FWS7   B4QVI8   Q95T98   A0A1W4VXQ5   A0A0R3NP99   A0A195CSY9   B4GDW9   A0A1Y1MLN6   A0A2A3ELP3   B4NIB7   B4JI95   A0A1A9W6N2   F4WLM1   A0A182PLE3   Q16VG4   A0A1S4FMR5   A0A0A9Z4G4   A0A067RGR0   A0A182K8R4   A0A182W353   A0A182NCS0   U5ETZ3   A0A182QFM6   A0A182XF38   A0A151XA50   A0A182J6Z7   W8AXR8   A0A1L8EIJ4   A0A182HVK6   A0A182RI53   Q7PHE2   A0A232FGZ5   A0A1Q3G0K7   A0A1Q3G0L3   A0A2M3Z940   A0A1Q3G0M3   A0A310SHJ3   A0A2M4CMQ7   A0A2M4CMW4   A0A2M4AQW2   K7J7Y4   A0A1I8P686   W5JG42   A0A0M4EJT0   A0A2P8Z876   A0A182KZX1   A0A0K8TMV7   A0A034VHB6   E2C8Q5   A0A182YJR0   A0A0K8URN1   A0A0K8V5J5   A0A1W4WQD4   A0A034VHC0   A0A1L8EI23   A0A1I8P5D4  

EC Number

2.3.1.199

Pubmed

19121390    28756777    18712529    26354079    23622113    22118469    + More
25474469    26334808    27129103    28887463    18362917    19820115    26369729    25315136    17994087    25348373    18057021    24508170    30249741    20798317    15632085    23185243    17550304    25830018    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    28004739    21719571    17510324    25401762    26823975    24845553    24495485    12364791    14747013    17210077    28648823    20075255    20920257    23761445    29403074    20966253    25244985   

EMBL

BABH01013313    KZ149892    PZC79019.1    AB264656    KQ459586    BAG30735.1    + More
KPI97808.1    KQ461073    KPJ09741.1    GAIX01007127    JAA85433.1    GDQN01009681    GDQN01006773    GDQN01003504    JAT81373.1    JAT84281.1    JAT87550.1    AGBW02011787    OWR46145.1    GFTR01004941    JAW11485.1    GECL01001796    JAP04328.1    GBBI01002413    JAC16299.1    GBGD01002208    JAC86681.1    GDKW01002097    JAI54498.1    GEDC01020363    GEDC01015159    GEDC01006393    GEDC01005729    JAS16935.1    JAS22139.1    JAS30905.1    JAS31569.1    MF279188    ATD85028.1    GECU01019121    JAS88585.1    GEBQ01022473    JAT17504.1    KQ971372    EFA09796.1    GECZ01020764    JAS49005.1    GDAI01001632    JAI15971.1    GECZ01006010    JAS63759.1    KQ414614    KOC68912.1    MG573190    AWJ25052.1    GDHF01027266    GDHF01014458    GDHF01013658    GDHF01012192    GDHF01005627    JAI25048.1    JAI37856.1    JAI38656.1    JAI40122.1    JAI46687.1    CH902617    EDV43467.1    GAKP01017160    GAKP01017158    GAKP01017154    GAKP01017151    JAC41792.1    CH940650    EDW67386.1    KRF83276.1    GFDF01002667    JAV11417.1    OUUW01000014    SPP88268.1    KK107085    QOIP01000008    EZA60006.1    RLU19768.1    CH480821    EDW54839.1    CH933806    EDW16724.1    CH954181    EDV47789.1    ABLF02039120    ABLF02039121    GL435347    EFN73422.1    UFQS01000831    UFQT01000831    SSX07116.1    SSX27459.1    KQ979039    KYN23389.1    GFXV01001990    MBW13795.1    CM000070    EAL28742.1    CM000160    EDW95669.1    GBXI01011591    JAD02701.1    KQ976738    KYM75895.1    KQ981208    KYN44772.1    CM000364    EDX11613.1    AY060267    AE014297    AAL25306.1    AAN13323.1    KRT01005.1    KQ977372    KYN03239.1    CH479182    EDW34630.1    GEZM01027911    JAV86583.1    KZ288222    PBC32079.1    CH964272    EDW83699.1    CH916369    EDV92976.1    GL888208    EGI64957.1    CH477593    EAT38554.1    GBHO01035038    GBHO01003487    GBHO01003486    GBHO01003483    GBHO01003482    GBHO01003481    GBRD01015936    GBRD01015934    GDHC01018821    GDHC01008178    JAG08566.1    JAG40117.1    JAG40118.1    JAG40121.1    JAG40122.1    JAG40123.1    JAG49890.1    JAP99807.1    JAQ10451.1    KK852651    KDR19452.1    GANO01002561    JAB57310.1    AXCN02001584    KQ982351    KYQ57246.1    GAMC01012775    GAMC01012774    JAB93780.1    GFDG01000353    JAV18446.1    APCN01005798    AAAB01008898    EAA44575.5    NNAY01000231    OXU29833.1    GFDL01001710    JAV33335.1    GFDL01001715    JAV33330.1    GGFM01004254    MBW25005.1    GFDL01001713    JAV33332.1    KQ768821    OAD53050.1    GGFL01002442    MBW66620.1    GGFL01002441    MBW66619.1    GGFK01009853    MBW43174.1    ADMH02001497    ETN62308.1    CP012526    ALC45265.1    ALC47358.1    PYGN01000151    PSN52697.1    GDAI01001911    JAI15692.1    GAKP01017053    JAC41899.1    GL453671    EFN75679.1    GDHF01023098    JAI29216.1    GDHF01018117    JAI34197.1    GAKP01017058    GAKP01017055    GAKP01017048    JAC41904.1    GFDG01000481    JAV18318.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000007266    UP000095301    + More
UP000053825    UP000005203    UP000007801    UP000008792    UP000268350    UP000053097    UP000279307    UP000001292    UP000009192    UP000092445    UP000008711    UP000007819    UP000000311    UP000078492    UP000001819    UP000002282    UP000078540    UP000078541    UP000000304    UP000000803    UP000192221    UP000078542    UP000008744    UP000242457    UP000007798    UP000001070    UP000091820    UP000007755    UP000075885    UP000008820    UP000027135    UP000075881    UP000075920    UP000075884    UP000075886    UP000076407    UP000075809    UP000075880    UP000075840    UP000075900    UP000007062    UP000215335    UP000002358    UP000095300    UP000000673    UP000092553    UP000245037    UP000075882    UP000008237    UP000076408    UP000192223   

PRIDE

H9IT43    Q95T98   

Pfam

PF01151   ELO

Interpro

IPR002076   ELO_fam       

ProteinModelPortal

H9IT43   A0A2W1BVK9   B2DBH6   A0A194R1L2   S4P8U6   A0A1E1WBM2   + More
A0A212EXD6   A0A224XG77   A0A0V0G986   A0A023F5B4   A0A069DSG8   A0A0P4VQ12   A0A1B6D8X5   A0A290Y213   A0A1B6INS9   A0A1B6L1U0   D6X365   A0A1B6FFP4   A0A0K8TP99   A0A1B6GMU5   A0A1I8M7X8   A0A0L7RD69   A0A3Q8FM02   A0A0K8VMK5   A0A088AIA2   B3M2T7   A0A034VI44   B4M0X5   A0A1L8DY78   A0A3B0KWA1   A0A026WWA2   B4I3P6   B4KA49   A0A1B0A8T5   B3P216   J9K2C4   E1ZZH1   A0A336KQL3   A0A195EEV2   A0A2H8TI43   Q295H0   B4PTT6   A0A0A1WVQ5   A0A195AV43   A0A195FWS7   B4QVI8   Q95T98   A0A1W4VXQ5   A0A0R3NP99   A0A195CSY9   B4GDW9   A0A1Y1MLN6   A0A2A3ELP3   B4NIB7   B4JI95   A0A1A9W6N2   F4WLM1   A0A182PLE3   Q16VG4   A0A1S4FMR5   A0A0A9Z4G4   A0A067RGR0   A0A182K8R4   A0A182W353   A0A182NCS0   U5ETZ3   A0A182QFM6   A0A182XF38   A0A151XA50   A0A182J6Z7   W8AXR8   A0A1L8EIJ4   A0A182HVK6   A0A182RI53   Q7PHE2   A0A232FGZ5   A0A1Q3G0K7   A0A1Q3G0L3   A0A2M3Z940   A0A1Q3G0M3   A0A310SHJ3   A0A2M4CMQ7   A0A2M4CMW4   A0A2M4AQW2   K7J7Y4   A0A1I8P686   W5JG42   A0A0M4EJT0   A0A2P8Z876   A0A182KZX1   A0A0K8TMV7   A0A034VHB6   E2C8Q5   A0A182YJR0   A0A0K8URN1   A0A0K8V5J5   A0A1W4WQD4   A0A034VHC0   A0A1L8EI23   A0A1I8P5D4  

KEGG

101740658    K10250 elongation of very long chain fatty acids protein 7 [EC:2.3.1.199] | (RefSeq) elongation of v

PATHWAY

00062    Fatty acid elongation - Bombyx mori (domestic silkworm)
01040    Biosynthesis of unsaturated fatty acids - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0102756   GO:0016021   GO:0102338   GO:0102336   GO:0006633   GO:0102337   GO:0030176   GO:0034625   GO:0030148   GO:0019367   GO:0042761   GO:0009922   GO:0034626   GO:0030497   GO:0016746   GO:0006412   GO:0043565   GO:0007155   GO:0005515   GO:0008237   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR11157  

Length:

302

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

121.70714

Exp number, first 60 AAs:

19.23419

Total prob of N-in:

0.50556

POSSIBLE N-term signal

sequence

inside

1  -  49

TMhelix

50  -  72

outside

73  -  100

TMhelix

101  -  120

inside

121  -  126

TMhelix

127  -  146

outside

147  -  155

TMhelix

156  -  178

inside

179  -  190

TMhelix

191  -  210

outside

211  -  219

TMhelix

220  -  237

inside

238  -  302

 

 

Pi

210.095787

Theta

171.965441

Tajima's D

0.614918

CLR

0.237256

CSRT

0.552022398880056

Interpretation

Uncertain