Gene

KWMTBOMO13031

Pre Gene Modal

BGIBMGA000424

Annotation

PREDICTED:_elongation_of_very_long_chain_fatty_acids_protein_AAEL008004_isoform_X1_[Papilio_machaon]

Location

Bomo_Chr22(-):6702517-6734921      View in EpiBrowser

Full name

Elongation of very long chain fatty acids protein       + More
Elongation of very long chain fatty acids protein AAEL008004      

Alternative Name

Very-long-chain 3-oxoacyl-CoA synthase
3-keto acyl-CoA synthase AAEL008004
Very-long-chain 3-oxoacyl-CoA synthase AAEL008004

Location in the cell

PlasmaMembrane   Reliability : 4.532

CDS

ATGGCACTAATACTGGAATATTTAAATGATATGCACGTATTTATGGATAAATATGGAGACCCTCGGACTAATCCATGGTTCCTTATGAGCTCACCTTTACCCACATTAATTATATGTTTAAGTTATGTCTATCTAGTCAAGGTTTTAGGGCCACAATTTATGGAAAATAGAAAACCATATGAATTAAAAAATCTTCTAATATTATATAACTTTCTCCAAGTAATATTCAGTGCATGGCTTTTCTACGAGATTGGGGCCGCGGGCTGGTTCACAGGCAGGTATAACTTTCAATGTCAGCCGGTCGACCACTCGAAACATCCACAAACAATGAGGATGGTACATGCGTGTTGGTGGTATTATTTCTCAAAGTTCACGGAGTTTTTTGATACGATCTTCTTTGTGCTGAGAAAGAAATTTGATCATGTATCAACATTGCACGTGATCCACCACGGAGTGATGCCCATGTCCGTTTGGTTCGGAGTGAAATTCACGCCAGGCGGACACTCTACGTTCTTCGGACTCCTCAATACGTTTGTACACATCGTCATGTATACCTACTACATGCTAGCAGCTATGGGCCCTCACATGAGGAAATATCTATGGTGGAAGAAATATTTGACAACTCTGCAAATGGTGCAATTCGTCGGCATCATGGTACATGCATTCCAGTTGTTGTTCATCGAATGCGACTACCCTCGTGCATTCGTTTGGTGGATAGGAATGCACGCGGTCATGTTTTTCTTCCTATTCAAGGACTTCTACGACCAATCTTACTCTAAACCTAAGGTGCGCGCCAAGTCTCCGCAGCCGGAACTGGAGACGACCGAGATCAAAGAGCTGACCTACCAGAACGGTTCGCTAAAGAACGGATTCAACAAAATTCACACGAACGGCACGATGCCGCGCGCCCGCACCGTTCTGCCGGCCGGCAACTGA

Protein

MALILEYLNDMHVFMDKYGDPRTNPWFLMSSPLPTLIICLSYVYLVKVLGPQFMENRKPYELKNLLILYNFLQVIFSAWLFYEIGAAGWFTGRYNFQCQPVDHSKHPQTMRMVHACWWYYFSKFTEFFDTIFFVLRKKFDHVSTLHVIHHGVMPMSVWFGVKFTPGGHSTFFGLLNTFVHIVMYTYYMLAAMGPHMRKYLWWKKYLTTLQMVQFVGIMVHAFQLLFIECDYPRAFVWWIGMHAVMFFFLFKDFYDQSYSKPKVRAKSPQPELETTEIKELTYQNGSLKNGFNKIHTNGTMPRARTVLPAGN

Description

Could be implicated in synthesis of very long chain fatty acids.

Catalytic Activity

a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA

Similarity

Belongs to the ELO family.

Keywords

Complete proteome   Fatty acid biosynthesis   Fatty acid metabolism   Lipid biosynthesis   Lipid metabolism   Membrane   Reference proteome   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  Elongation of very long chain fatty acids protein AAEL008004

Uniprot

A0A2W1BVD6   A0A194QW86   A0A194PWR4   A0A212EXH7   A0A2H1V4D9   A0A1E1W7T1   + More
A0A3S2TCH4   A0A1Y1M7G3   A0A0K8TMV7   A0A1B6EK88   A0A3Q8G639   A0A034VF14   A0A067RJR9   A0A023F4L2   A0A1B0CF33   W8BLU2   A0A0V0GAQ6   A0A1L8EHX7   A0A1L8DYD7   A0A232F9G3   A0A034VK19   A0A1I8MHJ2   A0A034VJB6   A0A1I8P5I0   W8B0N6   A0A336MQB5   A0A182YJR1   A0A1B6FBI1   A0A1I8MHI1   B4NIB9   A0A0C9RVW1   A0A3B0KQW4   T1D467   A0A158NS34   A0A1I8P5B7   A0A1Y1M310   A0A1A9W6N3   A0A336MZI3   A0A182NCS1   A0A0K8SD51   A0A0T6AYA0   A0A0P8YNC0   A0A1Q3EUC1   A0A1Q3EUD7   A0A1J1I561   T1DLJ9   A0A2M4CIS7   T1D484   A0A0R3NJ11   A0A1J1I8Z1   A0A2P8Z4M0   A0A2M4BRZ1   A0A2M4ANY0   A0A1W4VXP9   A0A034VHB6   A0A0Q9XFD6   A0A1J1I516   A0A1Q3EUC6   B4M0X6   A0A0R1DZW8   A0A0K8URN1   Q1HRV8   A0A1L8EI23   D6X1G2   A0A0A1XHP0   A0A1W7R8B4   Q8IPL8   A0A0A9WPG5   K7J7Y3   A0A182W354   A0A182UY26   C6K8D2   F5HLM2   A0A1A9VN84   A0A1B0A8T6   A0A0K8V5J5   A0A034VHC0   A0A034VIE3   A0A034VK23   W8AWW5   A0A2H1V9U8   A0A2H8TN76   A0A1I8MHI3   A0A0Q9WVN5   A0A1I8P5D4   A0A0L0CAQ4   A0A034VF19   A0A2R7VWM8   E0W1G4   A0A1A9XMZ1   B3M2T8   A0A195BBF7   A0A146LEX3   A0A1W4WQD4   B4GDX0   A0A2J7R9L9   J9JRR1   A0A182QM92   A0A3B0K1T3   Q295G9  

EC Number

2.3.1.199

Pubmed

28756777    26354079    22118469    28004739    26369729    25348373    + More
24845553    25474469    24495485    28648823    25315136    25244985    17994087    24330624    21347285    18057021    15632085    29403074    17550304    17204158    17510324    18362917    19820115    25830018    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25401762    26823975    20075255    20410035    24945155    12364791    14747013    17210077    26108605    20566863   

EMBL

KZ149892    PZC79018.1    KQ461073    KPJ09742.1    KQ459586    KPI97806.1    + More
AGBW02011787    OWR46144.1    ODYU01000613    SOQ35703.1    GDQN01007992    GDQN01000519    JAT83062.1    JAT90535.1    RSAL01000386    RVE42029.1    GEZM01041641    JAV80245.1    GDAI01001911    JAI15692.1    GECZ01031419    GECZ01031175    GECZ01028076    JAS38350.1    JAS38594.1    JAS41693.1    MG573184    AWJ25046.1    GAKP01017051    JAC41901.1    KK852470    KDR23248.1    GBBI01002470    JAC16242.1    AJWK01009621    AJWK01009622    AJWK01009623    AJWK01009624    AJWK01009625    AJWK01009626    AJWK01009627    GAMC01015951    JAB90604.1    GECL01001006    JAP05118.1    GFDG01000482    JAV18317.1    GFDF01002623    JAV11461.1    NNAY01000641    OXU27242.1    GAKP01017057    GAKP01017054    GAKP01017052    JAC41898.1    GAKP01017056    GAKP01017047    JAC41905.1    GAMC01015954    GAMC01015952    JAB90603.1    UFQT01001482    UFQT01001654    SSX30749.1    SSX31319.1    GECZ01022288    JAS47481.1    CH964272    EDW83701.2    GBYB01013095    JAG82862.1    OUUW01000014    SPP88266.1    GALA01001078    JAA93774.1    ADTU01024445    ADTU01024446    ADTU01024447    ADTU01024448    ADTU01024449    ADTU01024450    ADTU01024451    ADTU01024452    GEZM01041642    JAV80244.1    SSX30748.1    SSX31318.1    GBRD01014829    GBRD01014827    JAG50999.1    LJIG01022581    KRT79806.1    CH902617    KPU80280.1    GFDL01016131    JAV18914.1    GFDL01016128    JAV18917.1    CVRI01000041    CRK95429.1    GAMD01000401    JAB01190.1    GGFL01001084    MBW65262.1    GALA01001058    JAA93794.1    CM000070    KRT01009.1    CRK95430.1    PYGN01000198    PSN51448.1    GGFJ01006633    MBW55774.1    GGFK01009173    MBW42494.1    GAKP01017053    JAC41899.1    CH933806    KRG02275.1    CRK95431.1    GFDL01016130    JAV18915.1    CH940650    EDW67387.2    KRF83279.1    CM000160    KRK02605.1    GDHF01023098    JAI29216.1    DQ439986    CH477478    GFDG01000481    JAV18318.1    KQ971371    EFA09483.1    GBXI01017108    GBXI01014026    GBXI01003791    GBXI01000224    JAC97183.1    JAD00266.1    JAD10501.1    JAD14068.1    GEHC01000269    JAV47376.1    AE014297    BT003296    AAN13319.2    AAO25056.1    GBHO01033985    GDHC01002901    JAG09619.1    JAQ15728.1    GQ168593    GAPW01002227    ACS37245.1    JAC11371.1    AAAB01008898    EGK97155.1    GDHF01018117    JAI34197.1    GAKP01017058    GAKP01017055    GAKP01017048    JAC41904.1    GAKP01017050    JAC41902.1    GAKP01017049    JAC41903.1    GAMC01015953    JAB90602.1    ODYU01001237    SOQ37172.1    GFXV01003818    MBW15623.1    KRF99860.1    JRES01000657    KNC29483.1    GAKP01017046    JAC41906.1    KK854125    PTY11739.1    DS235870    EEB19470.1    EDV43468.1    KQ976528    KYM81868.1    GDHC01011928    JAQ06701.1    CH479182    EDW34631.1    NEVH01006582    PNF37535.1    ABLF02034170    AXCN02001584    SPP88265.1    EAL28743.2   

Proteomes

UP000053240    UP000053268    UP000007151    UP000283053    UP000027135    UP000092461    + More
UP000215335    UP000095301    UP000095300    UP000076408    UP000007798    UP000268350    UP000005205    UP000091820    UP000075884    UP000007801    UP000183832    UP000001819    UP000245037    UP000192221    UP000009192    UP000008792    UP000002282    UP000008820    UP000007266    UP000000803    UP000002358    UP000075920    UP000075903    UP000007062    UP000078200    UP000092445    UP000037069    UP000009046    UP000092443    UP000078540    UP000192223    UP000008744    UP000235965    UP000007819    UP000075886   

PRIDE

Q8IPL8   

Pfam

PF01151   ELO

Interpro

IPR002076   ELO_fam       

ProteinModelPortal

A0A2W1BVD6   A0A194QW86   A0A194PWR4   A0A212EXH7   A0A2H1V4D9   A0A1E1W7T1   + More
A0A3S2TCH4   A0A1Y1M7G3   A0A0K8TMV7   A0A1B6EK88   A0A3Q8G639   A0A034VF14   A0A067RJR9   A0A023F4L2   A0A1B0CF33   W8BLU2   A0A0V0GAQ6   A0A1L8EHX7   A0A1L8DYD7   A0A232F9G3   A0A034VK19   A0A1I8MHJ2   A0A034VJB6   A0A1I8P5I0   W8B0N6   A0A336MQB5   A0A182YJR1   A0A1B6FBI1   A0A1I8MHI1   B4NIB9   A0A0C9RVW1   A0A3B0KQW4   T1D467   A0A158NS34   A0A1I8P5B7   A0A1Y1M310   A0A1A9W6N3   A0A336MZI3   A0A182NCS1   A0A0K8SD51   A0A0T6AYA0   A0A0P8YNC0   A0A1Q3EUC1   A0A1Q3EUD7   A0A1J1I561   T1DLJ9   A0A2M4CIS7   T1D484   A0A0R3NJ11   A0A1J1I8Z1   A0A2P8Z4M0   A0A2M4BRZ1   A0A2M4ANY0   A0A1W4VXP9   A0A034VHB6   A0A0Q9XFD6   A0A1J1I516   A0A1Q3EUC6   B4M0X6   A0A0R1DZW8   A0A0K8URN1   Q1HRV8   A0A1L8EI23   D6X1G2   A0A0A1XHP0   A0A1W7R8B4   Q8IPL8   A0A0A9WPG5   K7J7Y3   A0A182W354   A0A182UY26   C6K8D2   F5HLM2   A0A1A9VN84   A0A1B0A8T6   A0A0K8V5J5   A0A034VHC0   A0A034VIE3   A0A034VK23   W8AWW5   A0A2H1V9U8   A0A2H8TN76   A0A1I8MHI3   A0A0Q9WVN5   A0A1I8P5D4   A0A0L0CAQ4   A0A034VF19   A0A2R7VWM8   E0W1G4   A0A1A9XMZ1   B3M2T8   A0A195BBF7   A0A146LEX3   A0A1W4WQD4   B4GDX0   A0A2J7R9L9   J9JRR1   A0A182QM92   A0A3B0K1T3   Q295G9  

KEGG

101741086    no KO assigned | (RefSeq) elongation of very long chain fatty acids protein AAEL008004

GO

GO:0102756   GO:0102338   GO:0016021   GO:0102336   GO:0102337   GO:0006633   GO:0030176   GO:0034626   GO:0009922   GO:0042761   GO:0019367   GO:0030148   GO:0034625   GO:0030497   GO:0016746   GO:0006412   GO:0043565   GO:0007155   GO:0005515   GO:0008237   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR11157  

Subcellular location

Membrane  

Length:

311

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

138.42818

Exp number, first 60 AAs:

21.82548

Total prob of N-in:

0.02414

POSSIBLE N-term signal

sequence

outside

1  -  22

TMhelix

23  -  45

inside

46  -  64

TMhelix

65  -  87

outside

88  -  112

TMhelix

113  -  135

inside

136  -  141

TMhelix

142  -  161

outside

162  -  170

TMhelix

171  -  193

inside

194  -  204

TMhelix

205  -  227

outside

228  -  230

TMhelix

231  -  250

inside

251  -  311

 

 

Pi

226.475003

Theta

181.530935

Tajima's D

0.611787

CLR

0.256346

CSRT

0.543122843857807

Interpretation

Uncertain