Silkworm Genome Informatics Database

Gene

KWMTBOMO12978

Annotation

PREDICTED:_uncharacterized_protein_LOC106125507_[Papilio_xuthus]

Location

Bomo_Chr22(+):6094566-6098876 View in EpiBrowser

Full name

UDP-N-acetylmuramate--L-alanine ligase

Alternative Name

UDP-N-acetylmuramoyl-L-alanine synthetase

Location in the cell

Extracellular Reliability : 1.421 Nuclear Reliability : 1.264

CDS

ATGCAGTCAATTGACTTAGTAATATTATTGTTTAATATATTTAGTGTGGTTTCATGTTTACCGACAGTCCAAAGTGGATCAGAAACGAAACCAGAGTTCAAAGACGAAAAACGTTATCCAAATGGGACAGTTATTGGGACGTACACTTACATTGATAAAGAAGGAACGCCTGTCCATGTCCAATATTATGCAGACAACAATAGTTACGGGGTCGAATTAAAAAGTGTGAAAGTGTATAATGAAGCTGAACCGAAAGATTTCGATCTGTTTGCGAAAACAATGGAAACTCCTCTTAAAGTTGCTTCGGATCTTTTAAAGTACGACTTTGACAGAGTCCATGACGTTTATCGATCAAAACAAAATGAAATTGATAAGATTGATAATAATTTAAAGTCCGATAAAAAAAAAGGCGATTACGAAGTTTTGTATAATAATGGATACAATTCGTTAAAAAATAATGCTAAAAATAAAATAAAAATTTATTCTGGAAAAGAAAAAAGGAAAACTCGAAATATTCGAGATGATTATGACAAATCACTTTTTTGTTATAAATGA

Protein

MQSIDLVILLFNIFSVVSCLPTVQSGSETKPEFKDEKRYPNGTVIGTYTYIDKEGTPVHVQYYADNNSYGVELKSVKVYNEAEPKDFDLFAKTMETPLKVASDLLKYDFDRVHDVYRSKQNEIDKIDNNLKSDKKKGDYEVLYNNGYNSLKNNAKNKIKIYSGKEKRKTRNIRDDYDKSLFCYK

Description

Cell wall formation.

Catalytic Activity

ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine

Similarity

Belongs to the MurCDEF family.

Uniprot

A0A3S2P4W9 A0A212EP54 A0A194QWV2 A0A2E8XWF4

EC Number

6.3.2.8

Pubmed

22118469 26354079 29337314

EMBL

RSAL01000021 RVE52464.1 AGBW02013536 OWR43259.1 KQ461073 KPJ09784.1 + More
PBWM01000020 MBS30337.1

Proteomes

UP000283053 UP000007151 UP000053240

Pfam

PF00379   Chitin_bind_4        + More
PF08245   Mur_ligase_M
PF02875   Mur_ligase_C
PF01225   Mur_ligase

Interpro

IPR031311   CHIT_BIND_RR_consensus        + More
IPR000618   Insect_cuticle
IPR005758   UDP-N-AcMur_Ala_ligase_murC
IPR013221   Mur_ligase_cen
IPR004101   Mur_ligase_C
IPR036565   Mur-like_cat_sf
IPR000713   Mur_ligase_N
IPR036615   Mur_ligase_C_dom_sf

SUPFAM

SSF53244 SSF53244 + More
SSF53623 SSF53623

Gene 3D

3.40.1190.10 3.90.190.20

ProteinModelPortal

A0A3S2P4W9 A0A212EP54 A0A194QWV2 A0A2E8XWF4

KEGG

101742561 no KO assigned | (RefSeq) uncharacterized LOC101742561

GO

GO:0042302 GO:0005737 GO:0009252 GO:0008360 GO:0008763 GO:0051301 GO:0005524 GO:0007049 GO:0071555 GO:0005761 GO:0006412 GO:0043565 GO:0007155 GO:0005515 GO:0008237 GO:0008152 GO:0016491 GO:0015930

Subcellular location

Cytoplasm

SignalP

Position: 1 - 25, Likelihood: 0.987096

Length:

184

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.59761

Exp number, first 60 AAs:

3.59758

Total prob of N-in:

0.18382

outside

1 - 184

Pi

169.424318

Theta

166.756122

Tajima's D

0

CLR

0.421347

CSRT

0.365681715914204

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics