Gene

KWMTBOMO12959  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000452

Annotation

innexin_3_[Bombyx_mori]

Location

Bomo_Chr22(-):5429249-5440030      View in EpiBrowser

Full name

Innexin      

Location in the cell

PlasmaMembrane   Reliability : 4.466

CDS

ATGGCTGTTTTCGGTTTGGTATCATCAGTAGCGGGCTTCGTGAAAGTCCGCTATCTGATCGACAAGGCTGTCATCGATAACATGGTGTTCCGTATGCACTATCGGATCACATCGGCCATACTGTTTCTTTGTTGCATACTCGTTACGGCTAATAACCTGATCGGTGAACCCATTGCTTGCATTAGTGACGGCGCTAACCCTGGACACGTGATCAATACGTTCTGCTGGATCACGTACACATTCACCATGCCGAATACTACATCTAAAACCGCAGCCCATCCTGGTCTCGGCGACGACAATGATGAGAAACGCATACACTCTTACTATCAATGGGTACCGTTCATGCTGTTCTTCCAGGGCCTACTTTTTTACATTCCTCATTGGATTTGGAAGAACTGGGAAGAAGGAAAAGTCCGTCTGATTTCAGAAGGCATGAGAGGCACAATGGCCAGTATAGCTGATGACAAAAACAATCGTCAGAATCGACTCGTTCAATATTTGTTGGATACGTTGCACATGCACAACACTTACTCCTTCGGTTACTTCTTCTGCGAAGTGTTAAATTTCGCTAATGTCGTGGGAAACATATTTTTCTTGGACACATTCCTTGGCGGCGCATTCTTGACCTACGGCACCGACGTAGTCAGATTCTCCAATATGAATCAAGAGCAACGAACAGATCCAATGATCGAAGTTTTCCCGAGAATTACTAAATGTACATTCCATAAGTTCGGTGCCTCTGGAACGATACAAAAACACGACGCGCTTTGCGTCCTCGCTTTGAATATTCTTAACGAGAAAATTTTCATCTTCCTGTGGTTCTGGTTCATCATCCTGTCAGTGGTTTCCGGACTGGCACTGGTATACTCGGCTGCGGTATGTTTATTGCCAAGCACTCGTGAGACTATACTCAAAAGAAGATTCCGGTTCGGAACACCAAACGGCGTCGAAGCGCTCGTTAGGAAGACACAGGTCGGCGATTTCTTGCTTCTACATCTGCTGGGCCAGAATATGTCGTTGCGAGTGTTTGGTGAAGTTTTGGATGAGCTATCACGAAGACTTAATCTAGGTTCCCATGCTCCGTCAGCTCCGTCGACGCTCGAGATGGCTCCTATTTATCCTGACATTGACAAGTATTCTAAGGAAACCGAAACGTAA

Protein

MAVFGLVSSVAGFVKVRYLIDKAVIDNMVFRMHYRITSAILFLCCILVTANNLIGEPIACISDGANPGHVINTFCWITYTFTMPNTTSKTAAHPGLGDDNDEKRIHSYYQWVPFMLFFQGLLFYIPHWIWKNWEEGKVRLISEGMRGTMASIADDKNNRQNRLVQYLLDTLHMHNTYSFGYFFCEVLNFANVVGNIFFLDTFLGGAFLTYGTDVVRFSNMNQEQRTDPMIEVFPRITKCTFHKFGASGTIQKHDALCVLALNILNEKIFIFLWFWFIILSVVSGLALVYSAAVCLLPSTRETILKRRFRFGTPNGVEALVRKTQVGDFLLLHLLGQNMSLRVFGEVLDELSRRLNLGSHAPSAPSTLEMAPIYPDIDKYSKETET

Description

Structural component of the gap junctions.

Similarity

Belongs to the pannexin family.

Feature

chain  Innexin

Uniprot

H9IT73   B7U9X6   A0A2A4K0X0   K9RZK7   S4PBP2   A0A3G1PLL2   + More
A0A1E1WI21   I4DN96   A0A194QW93   A0A2H1VX70   A0A212F4N9   A0A194Q988   A0A1W4XSA6   D6X0D3   A0A232FC75   E2AUZ7   A0A088AID2   A0A2A3EKM6   E2BAV2   A0A154P9Y4   A0A151X8N2   A0A0C9QJQ2   A0A310SDX5   A0A0J7KFC1   A0A195ATV3   A0A158NPV6   A0A151IHI3   F4W7D6   A0A0T6AWJ1   A0A151JSR9   A0A026WWJ5   A0A195DTQ6   A0A2P8YHY4   A0A1B6KPH5   A0A1B6GUF3   A0A182PP64   A0A182NGH0   A0A182M1Z1   A0A182JRU8   A0A182Y8R0   A0A2M3Z359   A0A2M4BQU8   A0A182RE29   A0A182W3H4   A0A2M4A5M4   A0A182FAM7   W5J1S6   A0A182TQV8   A0A023ESH3   A0A182QG05   A0A182HF50   A0A182L2S3   A0A182HYQ5   Q16QK9   A0A182XIH4   T1E2Q0   A0A075M4U6   A0A1S4FT50   A0A0L7RDI7   A0A182V5Z4   E0VNL8   Q7Q9Z6   A0A075M4I1   A0A1Q3FNY4   A0A1B6BWP0   A0A1Q3FP12   A0A2J7PSE5   B0X6R5   T1D6D2   U5EZ77   A0A182JA93   A0A1S3CXD3   A0A023F482   A0A1L8E367   T1I6M9   A0A0V0G6T3   Q5XUA2   A0A1B6JAV4   A0A2S2QIB7   A0A2H8TSZ7   A0A224XDV8   A0A2S2NNK0   J9JWH0   A0A069DTP9   A0A336M2F4   A0A0A9WAN6   A0A1B0CI13   N6U8L4   U4UDN4   A0A1J1JAC4   A0A1I8MBQ8   A0A1I8P752   A0A1A9WEF9   A0A1B0FDH7   A0A1A9VAH4   A0A1B0A0G2   A0A182SCY0   A0A1Q3FNX7   B4NKS4   A0A0M9A171  

Pubmed

19121390    19415533    23622113    29361596    22651552    26354079    + More
22118469    18362917    19820115    28648823    20798317    21347285    21719571    24508170    30249741    29403074    25244985    20920257    23761445    24945155    26483478    20966253    17510324    24330624    25585357    20566863    12364791    25474469    26334808    25401762    26823975    23537049    25315136    17994087   

EMBL

BABH01013423    BABH01013424    FJ463039    ACK38254.1    NWSH01000333    PCG77320.1    + More
KC018472    AFY62976.1    GAIX01004521    JAA88039.1    MG000944    AVM81262.1    GDQN01004415    JAT86639.1    AK402784    BAM19386.1    KQ461073    KPJ09808.1    ODYU01005002    SOQ45447.1    AGBW02010334    OWR48705.1    KQ459324    KPJ01550.1    KQ971372    EFA09591.1    NNAY01000509    OXU27937.1    GL442958    EFN62743.1    KZ288222    PBC32044.1    GL446860    EFN87180.1    KQ434856    KZC08746.1    KQ982409    KYQ56736.1    GBYB01003744    JAG73511.1    KQ760869    OAD58782.1    LBMM01008141    KMQ89113.1    KQ976745    KYM75487.1    ADTU01022766    KQ977606    KYN01423.1    GL887844    EGI69809.1    LJIG01022631    KRT79535.1    KQ982014    KYN30623.1    KK107105    QOIP01000011    EZA59499.1    RLU17101.1    KQ980487    KYN15909.1    PYGN01000582    PSN43853.1    GEBQ01026641    GEBQ01025246    GEBQ01023088    JAT13336.1    JAT14731.1    JAT16889.1    GECZ01003701    JAS66068.1    AXCM01004448    GGFM01002184    MBW22935.1    GGFJ01006251    MBW55392.1    GGFK01002607    MBW35928.1    ADMH02002159    ETN58197.1    GAPW01001882    JAC11716.1    AXCN02001607    JXUM01133535    KQ567992    KXJ69206.1    APCN01005396    CH477745    EAT36684.1    GALA01001095    JAA93757.1    KJ736825    AIF75097.1    KQ414614    KOC68874.1    AAZO01003917    DS235340    EEB14974.1    AAAB01008898    EAA09228.3    KJ736826    AIF75098.1    GFDL01005768    JAV29277.1    GEDC01031602    JAS05696.1    GFDL01005720    JAV29325.1    NEVH01021931    PNF19253.1    DS232421    EDS41548.1    GALA01000113    JAA94739.1    GANO01001289    JAB58582.1    GBBI01002387    GEMB01001828    JAC16325.1    JAS01343.1    GFDF01000923    JAV13161.1    ACPB03000870    GECL01002297    JAP03827.1    AY737552    AAU84945.1    GECU01037337    GECU01035501    GECU01011461    JAS70369.1    JAS72205.1    JAS96245.1    GGMS01008265    MBY77468.1    GFXV01002065    GFXV01005548    MBW13870.1    MBW17353.1    GFTR01005770    JAW10656.1    GGMR01006150    MBY18769.1    ABLF02034090    GBGD01001748    JAC87141.1    UFQS01000109    UFQT01000109    SSW99768.1    SSX20148.1    GBHO01040051    GDHC01010917    JAG03553.1    JAQ07712.1    AJWK01012959    APGK01044510    APGK01044511    KB741026    ENN74942.1    KB632309    ERL92084.1    CVRI01000075    CRL08502.1    CCAG010013497    GFDL01005750    JAV29295.1    CH964272    EDW84135.1    KQ435774    KOX75087.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000192223    + More
UP000007266    UP000215335    UP000000311    UP000005203    UP000242457    UP000008237    UP000076502    UP000075809    UP000036403    UP000078540    UP000005205    UP000078542    UP000007755    UP000078541    UP000053097    UP000279307    UP000078492    UP000245037    UP000075885    UP000075884    UP000075883    UP000075881    UP000076408    UP000075900    UP000075920    UP000069272    UP000000673    UP000075902    UP000075886    UP000069940    UP000249989    UP000075882    UP000075840    UP000008820    UP000076407    UP000053825    UP000075903    UP000009046    UP000007062    UP000235965    UP000002320    UP000075880    UP000079169    UP000015103    UP000007819    UP000092461    UP000019118    UP000030742    UP000183832    UP000095301    UP000095300    UP000091820    UP000092444    UP000078200    UP000092445    UP000075901    UP000007798    UP000053105   

PRIDE

H9IT73    B7U9X6   

Pfam

PF00876   Innexin

Interpro

IPR000990   Innexin       

ProteinModelPortal

H9IT73   B7U9X6   A0A2A4K0X0   K9RZK7   S4PBP2   A0A3G1PLL2   + More
A0A1E1WI21   I4DN96   A0A194QW93   A0A2H1VX70   A0A212F4N9   A0A194Q988   A0A1W4XSA6   D6X0D3   A0A232FC75   E2AUZ7   A0A088AID2   A0A2A3EKM6   E2BAV2   A0A154P9Y4   A0A151X8N2   A0A0C9QJQ2   A0A310SDX5   A0A0J7KFC1   A0A195ATV3   A0A158NPV6   A0A151IHI3   F4W7D6   A0A0T6AWJ1   A0A151JSR9   A0A026WWJ5   A0A195DTQ6   A0A2P8YHY4   A0A1B6KPH5   A0A1B6GUF3   A0A182PP64   A0A182NGH0   A0A182M1Z1   A0A182JRU8   A0A182Y8R0   A0A2M3Z359   A0A2M4BQU8   A0A182RE29   A0A182W3H4   A0A2M4A5M4   A0A182FAM7   W5J1S6   A0A182TQV8   A0A023ESH3   A0A182QG05   A0A182HF50   A0A182L2S3   A0A182HYQ5   Q16QK9   A0A182XIH4   T1E2Q0   A0A075M4U6   A0A1S4FT50   A0A0L7RDI7   A0A182V5Z4   E0VNL8   Q7Q9Z6   A0A075M4I1   A0A1Q3FNY4   A0A1B6BWP0   A0A1Q3FP12   A0A2J7PSE5   B0X6R5   T1D6D2   U5EZ77   A0A182JA93   A0A1S3CXD3   A0A023F482   A0A1L8E367   T1I6M9   A0A0V0G6T3   Q5XUA2   A0A1B6JAV4   A0A2S2QIB7   A0A2H8TSZ7   A0A224XDV8   A0A2S2NNK0   J9JWH0   A0A069DTP9   A0A336M2F4   A0A0A9WAN6   A0A1B0CI13   N6U8L4   U4UDN4   A0A1J1JAC4   A0A1I8MBQ8   A0A1I8P752   A0A1A9WEF9   A0A1B0FDH7   A0A1A9VAH4   A0A1B0A0G2   A0A182SCY0   A0A1Q3FNX7   B4NKS4   A0A0M9A171  

PDB

5H1R     E-value=6.9013e-12,     Score=170

KEGG

100233162    K22037 innexin | (RefSeq) Inx3; innexin 3

GO

GO:0016021   GO:0005886   GO:0006811   GO:0005921   GO:0007165   GO:0020037   GO:0050660   GO:0007155   GO:0005515   GO:0008237   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR11893  

Subcellular location

Cell membrane  
Cell junction  
Gap junction  

Length:

385

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

99.9058

Exp number, first 60 AAs:

23.94266

Total prob of N-in:

0.38424

POSSIBLE N-term signal

sequence

outside

1  -  35

TMhelix

36  -  55

inside

56  -  107

TMhelix

108  -  130

outside

131  -  188

TMhelix

189  -  211

inside

212  -  270

TMhelix

271  -  293

outside

294  -  385

 

 

Pi

164.820777

Theta

173.232782

Tajima's D

-0.378298

CLR

1.135594

CSRT

0.271236438178091

Interpretation

Uncertain