Gene

KWMTBOMO12946  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000235

Annotation

PREDICTED:_bifunctional_3'-phosphoadenosine_5'-phosphosulfate_synthase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr22(+):4908490-4923362      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.275

CDS

ATGGACGTCATCCGACTGCTGGAGTCCCAGGGTATCATTCCGAGCCTCGAGAGCAACCGTTCTGGAGTTGAAGAGCTCTTCATCCACGGGAACAGGCTCACCAGCGCCATCGAGGAGGCGGCCCGGCTACCACAGATTGAACTGACGACACTCGATTTGCAATGGGTTCAGGTTTTATCCGAAGGATGGGCGTATCCTTTAAAGGGATTTATGCGGGAAACCGAGTACTTACAGGCGCTTCATTCGAACTGCGTTACGCTGCCGGACGGGTCGCTAGTGAACCAGTCGGTGCCGGTGGTGTTGCCGGTGTCGGCCGAGCTGAAGGAGCGGCTGGCGGGCGCGGCGGCGGTGGCACTCACGCGCGGCGGCCGGCCCCTCGCCGTGCTGCGTGGCCCCGAGTTCTACCCGCACCGGAAGGAGGAGCGGTGCTCGCGGCAGTTCGGCATATACCACGCCGGTCACCCCTACATCAAGATGATCAAAGACTCCGGTGACTGGCTGGTAGGCGGCACCCTGGAGGTGTTCGAGCGGATCCGTTGGAACGACGGCCTGGACTCGTACCGCCTCACCCCCAACGAGCTCAGACAGAAGTTCAAGGACCTGGGGGCTGACGCCGTGTTCGCGTTCCAGTTGCGGAACCCGATCCACAACGGGCACGCGCTGCTGATGCAGGACACGCAGCGGCAACTGGTCGAGAGAGGATTCAAGAAACCCGTGCTCTTGTTACATCCGCTCGGCGGTTGGACGAAAGACGACGACGTGCCTCTAGAAGTGAGAATAAAACAACACAAAGCCGTGCTAAAGGAGGGAGTCTTGGATCCTAACTCCACTGTCCTGGCCATTTTCCCGTCCCCTATGATGTACGCCGGACCCACTGAGGTGCAGTGGCACGCCAAGTGTCGCATGAACGCCGGCGCCAACCACTACATAGTGGGGCGCGACCCGGCCGGCCTGCCGTACCCGCGCGGCGACGGCGACCTGTACGACCCGCGGCACGGCGCCATGCTGCTCAAGGTCGCGCCCGGACTCAACGACCTGGAGATAATTCCGTTCCGCGTGGCCGCCTACGATACGTCGGTGGGTAAGATGGCGTTCTTCGACCCGACGCGCAAAGAGGACTTCGACTTCATATCCGGAACGAGGATGAGAGGGCTCGCGAAGGCCGGCAAGGAGCCTCCGAGGGGCTTCATGGCGCCGACCGCCTGGAACGTTCTCGCCGAGTACTACCAGTCGATGAAATCCAAAATGGATACGAATTAA

Protein

MDVIRLLESQGIIPSLESNRSGVEELFIHGNRLTSAIEEAARLPQIELTTLDLQWVQVLSEGWAYPLKGFMRETEYLQALHSNCVTLPDGSLVNQSVPVVLPVSAELKERLAGAAAVALTRGGRPLAVLRGPEFYPHRKEERCSRQFGIYHAGHPYIKMIKDSGDWLVGGTLEVFERIRWNDGLDSYRLTPNELRQKFKDLGADAVFAFQLRNPIHNGHALLMQDTQRQLVERGFKKPVLLLHPLGGWTKDDDVPLEVRIKQHKAVLKEGVLDPNSTVLAIFPSPMMYAGPTEVQWHAKCRMNAGANHYIVGRDPAGLPYPRGDGDLYDPRHGAMLLKVAPGLNDLEIIPFRVAAYDTSVGKMAFFDPTRKEDFDFISGTRMRGLAKAGKEPPRGFMAPTAWNVLAEYYQSMKSKMDTN

Uniprot

A0A2A4IXA5   A0A2H1WEJ6   S4PXI3   A0A194Q7P1   A0A0N1PGA6   A0A2J7Q7Y1   + More
A0A2J7Q7Y5   A0A182Q0A7   E0W351   A0A084W067   Q7PX77   F5HMV2   V5GYZ7   D7EKF1   A0A182UEY1   B7P3J8   A0A182L8N9   W8BGD4   A0A0T6B7E6   F5HMV3   A0A182X9G4   A0A182V205   A0A182MPX3   A0A1Y9IV51   A0A1Y9IVV1   A0A1Y9IVX0   A0A2M4BGK2   A0A182RA51   A0A0A1WK45   A0A182HKE9   A0A2M4BHH6   A0A2M4A1Z9   A0A2M4A1W1   Q179J5   A0A034W308   A0A2M4A240   A0A2M4A284   A0A0P4VVW0   A0A2M4A1W7   A0A182FRZ8   A0A0A9ZCS8   A0A0A9YY03   T1PKZ2   T1J7Q2   A0A034W5Q0   A0A2M3Z5Q2   A0A1B6JPF9   W5J5A6   A0A0K8S8J3   T1PL68   A0A1I8MDT4   A0A1S3J702   A0A023F5B2   A0A2M3ZH96   A0A1S3J7A6   A0A161MSV4   A0A224YLU0   A0A182NQP4   A0A131YPQ9   A0A131YG23   A0A1B6JTU7   A0A1S3J8K0   T1I8C2   G3MPV1   L7M6S3   A0A069DZC3   A0A023EUU6   A0A2M4CLM3   A0A131XHN2   A0A0K8TXW2   A0A182GHQ8   V5G3R4   A0A067RA86   A0A182JCQ3   A0A0L0CF95   A0A182YQ18   A0A1I8PAV5   A0A1E1XAX5   A0A1A9UQG6   A0A182PRS4   A0A1I8PAQ4   A0A2G8L145   A0A1I8PAN7   A0A1A9XDC9   D3TLJ1   A0A1B0GD56   A0A1Q3FZ31   A0A0K8TT79   V4BE20   A0A1Q3FYW9   A0A1Q3FYV1   A0A1B0C0A8   A0A1A9ZS86   K7J476   A0A0J7KS12   N6TNS0   B3DJF3   A0A3S0ZGJ2   K1R185   A0A2A3E6X3  

Pubmed

23622113    26354079    20566863    24438588    12364791    14747013    + More
17210077    25765539    18362917    19820115    20966253    24495485    25830018    17510324    25348373    27129103    25401762    26823975    20920257    23761445    25315136    25474469    28797301    26830274    22216098    25576852    26334808    24945155    28049606    26483478    24845553    26108605    25244985    28503490    29023486    20353571    26369729    23254933    20075255    23537049    23594743    22992520   

EMBL

NWSH01005836    PCG63904.1    ODYU01008136    SOQ51489.1    GAIX01004988    JAA87572.1    + More
KQ459324    KPJ01557.1    KQ460968    KPJ10213.1    NEVH01017000    PNF24694.1    PNF24692.1    AXCN02001509    DS235882    EEB20057.1    ATLV01019092    KE525262    KFB43611.1    AAAB01008987    EAA01759.4    EGK97625.1    GANP01008628    JAB75840.1    DS497744    EFA13134.1    ABJB010347738    ABJB010864233    DS629251    EEC01170.1    GAMC01014214    JAB92341.1    LJIG01009419    KRT83118.1    EGK97624.1    AXCM01000640    GGFJ01002930    MBW52071.1    GBXI01015412    JAC98879.1    APCN01000826    GGFJ01003351    MBW52492.1    GGFK01001458    MBW34779.1    GGFK01001483    MBW34804.1    CH477349    EAT42895.1    GAKP01009858    JAC49094.1    GGFK01001526    MBW34847.1    GGFK01001613    MBW34934.1    GDKW01001778    JAI54817.1    GGFK01001456    MBW34777.1    GBHO01009158    GBHO01009155    GBHO01001345    GDHC01015777    JAG34446.1    JAG34449.1    JAG42259.1    JAQ02852.1    GBHO01009156    GBHO01009154    GBHO01001285    GDHC01019910    GDHC01005794    JAG34448.1    JAG34450.1    JAG42319.1    JAP98718.1    JAQ12835.1    KA649384    AFP64013.1    JH431938    GAKP01009859    JAC49093.1    GGFM01003098    MBW23849.1    GECU01006560    JAT01147.1    ADMH02002101    ETN59166.1    GBRD01016229    GBRD01014861    GBRD01014860    GBRD01003037    JAG49597.1    KA649497    AFP64126.1    GBBI01002418    JAC16294.1    GGFM01007153    MBW27904.1    GEMB01000561    JAS02569.1    GFPF01005563    MAA16709.1    GEDV01007304    JAP81253.1    GEDV01011127    JAP77430.1    GECU01005065    JAT02642.1    ACPB03000011    JO843902    AEO35519.1    GACK01005038    JAA59996.1    GBGD01000890    JAC87999.1    GAPW01000388    JAC13210.1    GGFL01002005    MBW66183.1    GEFH01001992    JAP66589.1    GDHF01033015    JAI19299.1    JXUM01064346    JXUM01064347    KQ562293    KXJ76223.1    GALX01003801    JAB64665.1    KK852601    KDR20503.1    JRES01000484    KNC30915.1    GFAC01002801    JAT96387.1    MRZV01000268    PIK53977.1    EZ422293    ADD18569.1    CCAG010002318    GFDL01002313    JAV32732.1    GDAI01000245    JAI17358.1    KB199905    ESP04012.1    GFDL01002325    JAV32720.1    GFDL01002318    JAV32727.1    JXJN01023506    AAZX01003267    LBMM01003797    KMQ93123.1    APGK01057391    APGK01057392    KB741280    ENN70895.1    CR788312    BC163464    BC163465    AAI63464.1    RQTK01000608    RUS77120.1    JH817156    EKC37239.1    KZ288361    PBC26976.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000235965    UP000075886    UP000009046    + More
UP000030765    UP000007062    UP000007266    UP000075902    UP000001555    UP000075882    UP000076407    UP000075903    UP000075883    UP000075920    UP000075900    UP000075840    UP000008820    UP000069272    UP000000673    UP000095301    UP000085678    UP000075884    UP000015103    UP000069940    UP000249989    UP000027135    UP000075880    UP000037069    UP000076408    UP000095300    UP000078200    UP000075885    UP000230750    UP000092443    UP000092444    UP000030746    UP000092460    UP000092445    UP000002358    UP000036403    UP000019118    UP000000437    UP000271974    UP000005408    UP000242457   

Pfam

PF01747   ATP-sulfurylase        + More
PF14306   PUA_2
PF07776   zf-AD
PF01704   UDPGP
PF15811   SVIP

Interpro

IPR002891   APS_kinase        + More
IPR027417   P-loop_NTPase       
IPR025980   ATP-Sase_PUA-like_dom       
IPR002650   Sulphate_adenylyltransferase       
IPR014729   Rossmann-like_a/b/a_fold       
IPR015947   PUA-like_sf       
IPR024951   Sulfurylase_cat_dom       
IPR016267   UDPGP_trans       
IPR002618   UDPGP_fam       
IPR029044   Nucleotide-diphossugar_trans       
IPR012934   Znf_AD       
IPR031632   SVIP       

SUPFAM

SSF52540   SSF52540        + More
SSF88697   SSF88697       
SSF53448   SSF53448       

Gene 3D

3.40.50.620     3.90.550.10    

CDD

cd00517  ATPS
cd02027  APSK
cd00897  UGPase_euk

ProteinModelPortal

A0A2A4IXA5   A0A2H1WEJ6   S4PXI3   A0A194Q7P1   A0A0N1PGA6   A0A2J7Q7Y1   + More
A0A2J7Q7Y5   A0A182Q0A7   E0W351   A0A084W067   Q7PX77   F5HMV2   V5GYZ7   D7EKF1   A0A182UEY1   B7P3J8   A0A182L8N9   W8BGD4   A0A0T6B7E6   F5HMV3   A0A182X9G4   A0A182V205   A0A182MPX3   A0A1Y9IV51   A0A1Y9IVV1   A0A1Y9IVX0   A0A2M4BGK2   A0A182RA51   A0A0A1WK45   A0A182HKE9   A0A2M4BHH6   A0A2M4A1Z9   A0A2M4A1W1   Q179J5   A0A034W308   A0A2M4A240   A0A2M4A284   A0A0P4VVW0   A0A2M4A1W7   A0A182FRZ8   A0A0A9ZCS8   A0A0A9YY03   T1PKZ2   T1J7Q2   A0A034W5Q0   A0A2M3Z5Q2   A0A1B6JPF9   W5J5A6   A0A0K8S8J3   T1PL68   A0A1I8MDT4   A0A1S3J702   A0A023F5B2   A0A2M3ZH96   A0A1S3J7A6   A0A161MSV4   A0A224YLU0   A0A182NQP4   A0A131YPQ9   A0A131YG23   A0A1B6JTU7   A0A1S3J8K0   T1I8C2   G3MPV1   L7M6S3   A0A069DZC3   A0A023EUU6   A0A2M4CLM3   A0A131XHN2   A0A0K8TXW2   A0A182GHQ8   V5G3R4   A0A067RA86   A0A182JCQ3   A0A0L0CF95   A0A182YQ18   A0A1I8PAV5   A0A1E1XAX5   A0A1A9UQG6   A0A182PRS4   A0A1I8PAQ4   A0A2G8L145   A0A1I8PAN7   A0A1A9XDC9   D3TLJ1   A0A1B0GD56   A0A1Q3FZ31   A0A0K8TT79   V4BE20   A0A1Q3FYW9   A0A1Q3FYV1   A0A1B0C0A8   A0A1A9ZS86   K7J476   A0A0J7KS12   N6TNS0   B3DJF3   A0A3S0ZGJ2   K1R185   A0A2A3E6X3  

PDB

1XNJ     E-value=1.96854e-158,     Score=1434

KEGG

101745840    K13811 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] | (RefSeq) bifunctional

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
00450    Selenocompound metabolism - Bombyx mori (domestic silkworm)
00920    Sulfur metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0000103   GO:0004781   GO:0004020   GO:0050428   GO:0008270   GO:0006011   GO:0003983   GO:0005634   GO:0005886   GO:0007155   GO:0005515   GO:0008237   GO:0008152   GO:0016491   GO:0015930  

Length:

419

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01012

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00582

outside

1  -  419

 

 

Pi

168.740702

Theta

175.784241

Tajima's D

0.318385

CLR

0.369926

CSRT

0.457977101144943

Interpretation

Possibly Positive selection