Gene

KWMTBOMO12941

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr22(+):4823020-4825587      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.519

CDS

ATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCATCGGATGCGTTACCACCCGTCACCCCGATAGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACTGTATATCTAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAACTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGATCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTAGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCCAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSIPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPIEVKDLIKDLRPRKAPGSDCISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGTLFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRSLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLRDPGNRTRPTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   V5GNF3   A0A139W8G9   A0A2S2PR14   J9KKL3   A0A2S2QEE0   X1WLB2   A0A2S2Q352   A0A2H8U0H5   A0A3N5Z7I3   A0A023EYS8   A0A224XF24   J9KCZ4   A0A2S2PPK8   Q07995   A0A2S2NGV8   J9KC83   A0A2S2N814   A0A2S2RAN7   A0A2J7R7D0   X1WNI2   A0A023EZE6   A0A1Y1LKN6   A0A224XB44   A0A023F6S4   J9LC21   A0A2M4BD67   A0A0C9RJA4   K7IN67   A0A2M4BDV6   A0A2J7RS81   A0A2S2Q383   X1WZH0   X1WN18   J9M522   A0A1Y1M7E9   A0A2J7PQB5   A0A2J7R8R8   A0A2J7Q627   A0A1L8DIZ6   A0A1Y1KFR3   A0A2J7PVX3   A0A2S2R9D4   A0A2J7PDM0   J9JS95   A0A069DZC5   X1WTA1   A0A224X6S1   J9LC15   A0A2A4K8E7   A0A069DW01   A0A2H8TKI9   A0A224X6Q4   A0A224XI99   Q95SX7   A0A2S2NH02   A0A2S2PBB4   A0A023F7D1   A0A2A4K918   A0A224XIB0   A0A1Y1KUU7   A0A2J7Q059   A0A224X6U5   A0A2J7QUJ9   J9KLB1   A0A2J7PMP6   A0A0J7MYU2   A0A2J7RIW7   Q9NBX4   A0A2J7R4B7   A0A2J7RM10   A0A2J7Q4F7   J9KPF1   A0A0J7K4E0   A0A2J7RL12   A0A2J7QTW2   A0A2J7QB68   A0A224X746  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
30086797    25474469    8387152    20075255    26334808    7753626    12537569    11405632   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    KQ973342    KXZ75569.1    GGMR01019198    MBY31817.1    ABLF02029306    ABLF02029314    ABLF02060138    GGMS01006359    MBY75562.1    ABLF02042518    ABLF02057746    GGMS01002955    MBY72158.1    GFXV01007093    MBW18898.1    RPOV01000134    RPJ78669.1    GBBI01004395    JAC14317.1    GFTR01008038    JAW08388.1    ABLF02008463    GGMR01018716    MBY31335.1    S59870    AAB26437.2    GGMR01003407    MBY16026.1    ABLF02033757    GGMR01000676    MBY13295.1    GGMS01017914    MBY87117.1    NEVH01006736    PNF36716.1    ABLF02008153    ABLF02008462    ABLF02008464    GBBI01004571    JAC14141.1    GEZM01053022    JAV74219.1    GFTR01008262    JAW08164.1    GBBI01001646    JAC17066.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGFJ01001858    MBW50999.1    GBYB01008290    JAG78057.1    GGFJ01001857    MBW50998.1    NEVH01000269    PNF43694.1    GGMS01002992    MBY72195.1    ABLF02034467    ABLF02021177    ABLF02027367    ABLF02066338    ABLF02024246    GEZM01038405    JAV81653.1    NEVH01022639    PNF18527.1    NEVH01006721    PNF37225.1    NEVH01017542    PNF24034.1    GFDF01007661    JAV06423.1    GEZM01084969    JAV60363.1    NEVH01020940    PNF20481.1    GGMS01017365    MBY86568.1    NEVH01026386    PNF14434.1    ABLF02028535    ABLF02028545    GBGD01000880    JAC88009.1    ABLF02037660    GFTR01008271    JAW08155.1    ABLF02020655    ABLF02039168    ABLF02061060    NWSH01000032    PCG80497.1    GBGD01000799    JAC88090.1    GFXV01002840    MBW14645.1    GFTR01008279    JAW08147.1    GFTR01008256    JAW08170.1    AY060438    AAL25477.1    GGMR01003864    MBY16483.1    GGMR01014053    MBY26672.1    GBBI01001570    JAC17142.1    PCG80496.1    GFTR01008246    JAW08180.1    GEZM01074951    JAV64378.1    NEVH01020071    PNF21969.1    GFTR01008251    JAW08175.1    NEVH01010546    PNF32261.1    ABLF02040174    ABLF02040183    ABLF02055266    NEVH01023962    PNF17612.1    LBMM01013518    KMQ85605.1    NEVH01003017    PNF40781.1    AF237761    AAF81411.1    NEVH01007443    PNF35684.1    NEVH01021586    NEVH01006600    NEVH01002584    PNF19589.1    PNF37419.1    PNF41868.1    NEVH01018383    PNF23463.1    ABLF02041767    LBMM01014395    KMQ85192.1    NEVH01002704    PNF41489.1    NEVH01011193    PNF32021.1    NEVH01016302    PNF25823.1    GFTR01008151    JAW08275.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000002358    UP000218220    + More
UP000036403   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q95SX7    Q9NBX4   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   V5GNF3   A0A139W8G9   A0A2S2PR14   J9KKL3   A0A2S2QEE0   X1WLB2   A0A2S2Q352   A0A2H8U0H5   A0A3N5Z7I3   A0A023EYS8   A0A224XF24   J9KCZ4   A0A2S2PPK8   Q07995   A0A2S2NGV8   J9KC83   A0A2S2N814   A0A2S2RAN7   A0A2J7R7D0   X1WNI2   A0A023EZE6   A0A1Y1LKN6   A0A224XB44   A0A023F6S4   J9LC21   A0A2M4BD67   A0A0C9RJA4   K7IN67   A0A2M4BDV6   A0A2J7RS81   A0A2S2Q383   X1WZH0   X1WN18   J9M522   A0A1Y1M7E9   A0A2J7PQB5   A0A2J7R8R8   A0A2J7Q627   A0A1L8DIZ6   A0A1Y1KFR3   A0A2J7PVX3   A0A2S2R9D4   A0A2J7PDM0   J9JS95   A0A069DZC5   X1WTA1   A0A224X6S1   J9LC15   A0A2A4K8E7   A0A069DW01   A0A2H8TKI9   A0A224X6Q4   A0A224XI99   Q95SX7   A0A2S2NH02   A0A2S2PBB4   A0A023F7D1   A0A2A4K918   A0A224XIB0   A0A1Y1KUU7   A0A2J7Q059   A0A224X6U5   A0A2J7QUJ9   J9KLB1   A0A2J7PMP6   A0A0J7MYU2   A0A2J7RIW7   Q9NBX4   A0A2J7R4B7   A0A2J7RM10   A0A2J7Q4F7   J9KPF1   A0A0J7K4E0   A0A2J7RL12   A0A2J7QTW2   A0A2J7QB68   A0A224X746  

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

736

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.83619000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04369

outside

1  -  736

 

 

Pi

36.011165

Theta

34.217894

Tajima's D

0.242518

CLR

0

CSRT

0.43762811859407

Interpretation

Uncertain