Gene

KWMTBOMO12903  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000474

Annotation

PREDICTED:_guanine_nucleotide-binding_protein-like_3_homolog_[Amyelois_transitella]

Location

Bomo_Chr22(-):3857857-3863511      View in EpiBrowser

Full name

Guanine nucleotide-binding protein-like 3 homolog      

Alternative Name

Nucleostemin 1
Nucleostemin homolog

Location in the cell

Nuclear   Reliability : 2.416

CDS

ATGAAGGGTTCAGCATGTGTTGGTGCAGAGTTACTAATGAGTCTTTTAGGCAACTATTGTCGAAATAAAGGCATTAAAACATCAATCACAGTTGGTGTCGTGGGACTCCCAAATGTCGGAAAGAGCTCTATAATCAATAGTTTGAATCGGTCCAAAGCTTGTAATGTGGGTAGCACTCCTGGAGTAACTAAGCAAATGCAAACTGTCCAACTAGATTCAAAGATCAAAATCCTGGACAGTCCTGGTATAGTATTCCAATCAGGCCCGGAGAGTGATTCAACGGTAGCACTCAAGAATGCTATCCGCGTTGGCAGCCTAAAAGACCCAGTCACACCGGCTACAGCTATCCTACAGAGGGCTAACAAGCAAACCTTACAAGATTTGTATAGAATACCAGACTTCAGTACACCTCAGGAATTCTTTGCGCAACTAGCACAACGAATGGGAAGGTTCAAAAAAGGTGGAGTTCCAGACCAAGAAGCAGCTTCTAGAATATTGCTCAATGACTGGAACATTGGTAAAGTACGCTATTTCACGGAGCCTCCCGAGACAGCAGACGCTGATATACACGTGGACGCCCAAATCGTGGCTTCCATCGCGAAGGAGTTCGACATCAACTCCTTCGAGGCCATGGAGACTGACATTGTTAACTCACTAAACACGGATTCCACTAAAATTGAACCTATAAAGATCACGAGCACGGGTCCAGTCGCGGCGGTGTTACCGGACCATATGCAAGTCGACGAGGAAGATTCCAGCATGCTGCCTAAAGCCTTGAACATACGGAACAGACTCGACAAGACGGGCAAGTCCCAGGAGAAGACGAAGGCGGACCCGGAGATGCTTCTAGAAGGGAACCTCAAACAGAATAAACTGAGGAAAATGCAATTCAAAAAGGACAAGAAGAAGAAGGCGAGGTCCGACAAGCAGGCCGTCGACCTGGCGGGCGTCTTGGAGAACGTTACATTGACTAAATACCCGAAAGAAGACGCAATAACCACGGACGACTACGATTTCAAAGAAGAATTCTCACTGTAG

Protein

MKGSACVGAELLMSLLGNYCRNKGIKTSITVGVVGLPNVGKSSIINSLNRSKACNVGSTPGVTKQMQTVQLDSKIKILDSPGIVFQSGPESDSTVALKNAIRVGSLKDPVTPATAILQRANKQTLQDLYRIPDFSTPQEFFAQLAQRMGRFKKGGVPDQEAASRILLNDWNIGKVRYFTEPPETADADIHVDAQIVASIAKEFDINSFEAMETDIVNSLNTDSTKIEPIKITSTGPVAAVLPDHMQVDEEDSSMLPKALNIRNRLDKTGKSQEKTKADPEMLLEGNLKQNKLRKMQFKKDKKKKARSDKQAVDLAGVLENVTLTKYPKEDAITTDDYDFKEEFSL

Description

May play a role in regulating cellular proliferation.

Similarity

Belongs to the TRAFAC class YlqF/YawG GTPase family.
Belongs to the AB hydrolase superfamily. Lipase family.

Keywords

Coiled coil   Complete proteome   GTP-binding   Nucleotide-binding   Nucleus   Phosphoprotein   Reference proteome  

Feature

chain  Guanine nucleotide-binding protein-like 3 homolog

Uniprot

H9IT94   A0A2A4J685   A0A2H1W0I7   A0A212F6K4   A0A194Q876   A0A1Y1KY29   + More
A0A2J7R9N2   D6WZU0   A0A2P8Z4M7   K7J6U0   A0A154PAA4   A0A0J7KPD6   A0A3L8DH32   A0A026VX11   A0A088ARM6   A0A195FWV2   A0A1L8DH89   A0A1I8PKW8   A0A2A3EJZ6   A0A1L8DHI6   A0A158NN67   A0A0K8TDB5   A0A146KQ38   A0A0A9YF83   A0A232F7G9   E2AMN3   A0A0M4ERC6   A0A195EF32   W8BFY1   A0A0L7QW33   A0A1I8MTR9   E2BEV6   A0A195CSW1   A0A0M9A9J6   F4WNW1   A0A151XA10   U4U918   B3M2A3   B4GDZ1   B4NJZ5   A0A0A1WD35   A0A224XA74   A0A069DVQ0   A0A1W4VQQ9   T1PA22   A0A3B0JQH1   B4PM82   Q8MT06   N6T6L3   B3P3I2   B4IBM6   B5DWM0   A0A0K8TQP6   T1HBR5   A0A151I465   A0A0K8U2X1   A0A034V1X3   A0A1B6IHY6   B4KC88   A0A034V087   B4M5J2   A0A0K8W4G8   A0A1B0FFP2   A0A1A9W576   A0A1B6G1X2   A0A1A9Z7D7   B4JHE5   B4QWC2   A0A1A9V509   A0A1A9X5W6   A0A1B0AWL3   A0A0K2V3J7   V5HQB4   A0A310SKD9   A0A131Y1D4   A0A0P6GMA0   A0A0P5MSG3  

Pubmed

19121390    22118469    26354079    28004739    18362917    19820115    + More
29403074    20075255    30249741    24508170    21347285    26823975    25401762    28648823    20798317    24495485    25315136    21719571    23537049    17994087    25830018    26334808    17550304    10731132    12537572    12537569    17372656    18628395    15632085    26369729    25348373    25765539   

EMBL

BABH01013561    NWSH01002717    PCG67627.1    ODYU01005517    SOQ46446.1    AGBW02010006    + More
OWR49354.1    KQ459324    KPJ01594.1    GEZM01070754    JAV66299.1    NEVH01006582    PNF37547.1    KQ971372    EFA10479.1    PYGN01000198    PSN51437.1    AAZX01001293    KQ434856    KZC08771.1    LBMM01004630    KMQ92228.1    QOIP01000008    RLU19755.1    KK107672    EZA48170.1    KQ981208    KYN44797.1    GFDF01008265    JAV05819.1    KZ288222    PBC32095.1    GFDF01008264    JAV05820.1    ADTU01021058    GBRD01002273    JAG63548.1    GDHC01020091    JAP98537.1    GBHO01013831    JAG29773.1    NNAY01000781    OXU26542.1    GL440840    EFN65301.1    CP012526    ALC47701.1    KQ979039    KYN23412.1    GAMC01018012    GAMC01018011    GAMC01018008    GAMC01018006    GAMC01018004    JAB88544.1    KQ414721    KOC62776.1    GL447881    EFN85760.1    KQ977372    KYN03214.1    KQ435720    KOX78639.1    GL888239    EGI64119.1    KQ982351    KYQ57222.1    KB632100    ERL88823.1    CH902617    EDV42294.1    CH479182    EDW33826.1    CH964272    EDW83997.1    GBXI01017408    JAC96883.1    GFTR01007170    JAW09256.1    GBGD01001008    JAC87881.1    KA644793    AFP59422.1    OUUW01000007    SPP83203.1    CM000160    EDW96948.1    AE014297    AY118455    BT050580    APGK01041783    KB740997    ENN75874.1    CH954181    EDV48762.1    CH480827    EDW44784.1    CM000070    EDY68160.1    GDAI01000929    JAI16674.1    ACPB03007652    KQ976475    KYM83907.1    GDHF01031210    JAI21104.1    GAKP01023400    JAC35558.1    GECU01021186    JAS86520.1    CH933806    EDW13697.1    GAKP01023401    JAC35557.1    CH940652    EDW58918.1    GDHF01006569    JAI45745.1    CCAG010018629    GECZ01013339    JAS56430.1    CH916369    EDV93852.1    CM000364    EDX12613.1    JXJN01004812    HACA01027499    CDW44860.1    GANP01004184    JAB80284.1    KQ760444    OAD60284.1    GEFM01003109    JAP72687.1    GDIQ01033266    JAN61471.1    GDIQ01151866    JAK99859.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000235965    UP000007266    + More
UP000245037    UP000002358    UP000076502    UP000036403    UP000279307    UP000053097    UP000005203    UP000078541    UP000095300    UP000242457    UP000005205    UP000215335    UP000000311    UP000092553    UP000078492    UP000053825    UP000095301    UP000008237    UP000078542    UP000053105    UP000007755    UP000075809    UP000030742    UP000007801    UP000008744    UP000007798    UP000192221    UP000268350    UP000002282    UP000000803    UP000019118    UP000008711    UP000001292    UP000001819    UP000015103    UP000078540    UP000009192    UP000008792    UP000092444    UP000091820    UP000092445    UP000001070    UP000000304    UP000078200    UP000092443    UP000092460   

PRIDE

H9IT94    Q8MT06   

Pfam

PF01926   MMR_HSR1        + More
PF08701   GN3L_Grn1
PF00069   Pkinase
PF00151   Lipase
PF01137   RTC
PF05189   RTC_insert

Interpro

IPR006073   GTP_binding_domain        + More
IPR030378   G_CP_dom       
IPR027417   P-loop_NTPase       
IPR023179   GTP-bd_ortho_bundle_sf       
IPR014813   Gnl3_N_dom       
IPR000719   Prot_kinase_dom       
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       
IPR017441   Protein_kinase_ATP_BS       
IPR000734   TAG_lipase       
IPR033906   Lipase_N       
IPR013818   Lipase/vitellogenin       
IPR029058   AB_hydrolase       
IPR023797   RNA3'_phos_cyclase_dom       
IPR037136   RNA3'_phos_cyclase_dom_sf       
IPR036553   RPTC_insert       
IPR013792   RNA3'P_cycl/enolpyr_Trfase_a/b       
IPR013791   RNA3'-term_phos_cycl_insert       
IPR017770   RNA3'_term_phos_cyc_type_1       

SUPFAM

SSF52540   SSF52540        + More
SSF56112   SSF56112       
SSF53474   SSF53474       
SSF52913   SSF52913       
SSF55205   SSF55205       

Gene 3D

1.10.1580.10     3.30.360.20     3.65.10.20    

CDD

cd00707  Pancreat_lipase_like

ProteinModelPortal

H9IT94   A0A2A4J685   A0A2H1W0I7   A0A212F6K4   A0A194Q876   A0A1Y1KY29   + More
A0A2J7R9N2   D6WZU0   A0A2P8Z4M7   K7J6U0   A0A154PAA4   A0A0J7KPD6   A0A3L8DH32   A0A026VX11   A0A088ARM6   A0A195FWV2   A0A1L8DH89   A0A1I8PKW8   A0A2A3EJZ6   A0A1L8DHI6   A0A158NN67   A0A0K8TDB5   A0A146KQ38   A0A0A9YF83   A0A232F7G9   E2AMN3   A0A0M4ERC6   A0A195EF32   W8BFY1   A0A0L7QW33   A0A1I8MTR9   E2BEV6   A0A195CSW1   A0A0M9A9J6   F4WNW1   A0A151XA10   U4U918   B3M2A3   B4GDZ1   B4NJZ5   A0A0A1WD35   A0A224XA74   A0A069DVQ0   A0A1W4VQQ9   T1PA22   A0A3B0JQH1   B4PM82   Q8MT06   N6T6L3   B3P3I2   B4IBM6   B5DWM0   A0A0K8TQP6   T1HBR5   A0A151I465   A0A0K8U2X1   A0A034V1X3   A0A1B6IHY6   B4KC88   A0A034V087   B4M5J2   A0A0K8W4G8   A0A1B0FFP2   A0A1A9W576   A0A1B6G1X2   A0A1A9Z7D7   B4JHE5   B4QWC2   A0A1A9V509   A0A1A9X5W6   A0A1B0AWL3   A0A0K2V3J7   V5HQB4   A0A310SKD9   A0A131Y1D4   A0A0P6GMA0   A0A0P5MSG3  

PDB

6FT6     E-value=2.66651e-26,     Score=294

KEGG

101736688    K14538 nuclear GTP-binding protein | (RefSeq) guanine nucleotide-binding protein-like 3 homolog

GO

GO:0005525   GO:0005730   GO:0004672   GO:0005524   GO:0003924   GO:0090307   GO:0042127   GO:0016887   GO:0040014   GO:0042273   GO:0001652   GO:0052689   GO:0005576   GO:0006629   GO:0006396   GO:0003963   GO:0005783   GO:0006457   GO:0051082   GO:0005515   GO:0045181   GO:0050660   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR11610  

Subcellular location

  
Secreted  

Length:

345

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01765

Exp number, first 60 AAs:

0.01765

Total prob of N-in:

0.01516

outside

1  -  345

 

 

Pi

218.874428

Theta

187.584914

Tajima's D

0.808115

CLR

0.188141

CSRT

0.602369881505925

Interpretation

Uncertain