Gene

KWMTBOMO12899  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014536

Annotation

heat_shock_protein_68_[Bombyx_mori]

Location

Bomo_Chr22(-):3732952-3735080      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.541

CDS

ATGCCTGCTATAGGGATAGATCTTGGAACTACATATTCATGTGTTGGAGTTTGGCAACATGGAAACGTGGAGATCATCGCTAACGACCAAGGAAACCGGACTACACCCTCATATGTTGCATTCACGGACACAGAGAGACTCATTGGTGATGCTGCTAAAAATCAAGTAGCACTCAACCCTAGTAATACGGTGTTCGATGCGAAAAGACTAATCGGTCGCAAGTTTGATGATGCCAAGATACAACAAGACCTGAAACATTGGCCATTCAAAGTGATAAGTGATTGTGGAAAGCCCAAAATCCAGATAGAATTCAAAGGCGAAACAAAACGTTTTGCACCTGAGGAAATCAGCAGTATGGTGTTAATAAAAATGAGAGAGACCGCTGAAGCATATCTTGGAACAGCAATACGAGATGCAGTCATCACCGTTCCTGCTTATTTTAACGATTCACAGCGTCAGGCCACAAAAGACGCTGGAGCTATCGCTGGTCTGAATGTGCTTCGTATTATAAATGAACCGACAGCAGCAGCACTCGCTTATGGATTGGATAAAAATTTAAAAGGCGAACGAAACGTTCTTATTTTCGACCTCGGTGGTGGAACATTCGATGTTTCCATACTGACCATTGATGAAGGTTCATTATTTGAGGTAAAAGCCACTGCAGGCGATACTCATCTAGGCGGTGAAGATTTTGATAATAGATTGGTGAACCACCTAGCTGAAGAGTTTAAACGGAAATACAAGAGAGATATAACCAGCAATCCTCGCGCTCTTCGCCGGCTTCGGACTGCAGCTGAACGGGCGAAACGAACATTATCATCGAGCACGGAAGCTACCATTGAAATAGATGCTTTGTACGAAGGCATTGATTTCTACACTAGAGTATCTCGTGCACGTTTTGAAGAATTAAATGCTGATCTGTTCCGAGGAACACTGGAACCTGTCGAGAAAGCTCTGAAAGATGCGAAACTAGATAAAAGCTCTATTCACGACGTAGTTCTCGTTGGAGGATCGACACGCATTCCAAAAATACAGAGCATGTTACAAAACTTCTTCTGTGGAAAGAAACTAAATCTTTCAATCAATCCGGATGAAGCGGTAGCATACGGAGCTGCTGTACAAGCAGCAATTTTGAGTGGAGAGCAACACAGTAAAATTCAAGATGTTCTTTTGGTTGACGTCGCTCCCTTATCTTTGGGCATTGAAACTGCCGGTGGTGTAATGACAAAGATCATTGAACGCAACGCTAAAATTCCATGCAAGCAATCACAGACATTCACGACATATTCTGACAGCCAACCAGCAGTCACAATACAAGTGTACGAGGGCGAACGGGCCATGACCAAGGACAACAATATGTTGGGTCGCTTCGATCTAACTGGAATTCCACCTGCACCACGGGGGGTCCCAAAGATCGACGTGACATTCGATATCGACGCCAACGGGATCTTAAATGTCTCCGCTAAAGAAAACGGCACTGGCCGCAGTAAAAACATCGTTATTAAAAATGATAAGGGACGATTATCTCAAGCTGAAATCGACCGTATGGTAGCAGAAGCCGAACGCTATAAGGAAGAAGATGATCGACAAAGAGAAAGGGTAGCAGCACGCAATCAATTGGAAACTTACATTTTCAACGTTAAACAAGCCGTTGATGATGCCGGTGACAAACTGAGCGCACAAGACAAAGAGAGCGTAAGAAACGATTGCGAGGCCGCCCTGCGATGGTTGGACAATAACACGCTAGCTGAAAAAGATGAATTTCAGCAGAAACTAAAGGATCTTCAGCAAGTTTGTTCACCAGTCATGAGCAAGATCCACGCTACGGGTAGTCAACAGTATTCACAGCCCAATCGTTCAGGGCCAACGGTTGAAGAAGTTGATTAA

Protein

MPAIGIDLGTTYSCVGVWQHGNVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPSNTVFDAKRLIGRKFDDAKIQQDLKHWPFKVISDCGKPKIQIEFKGETKRFAPEEISSMVLIKMRETAEAYLGTAIRDAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVKATAGDTHLGGEDFDNRLVNHLAEEFKRKYKRDITSNPRALRRLRTAAERAKRTLSSSTEATIEIDALYEGIDFYTRVSRARFEELNADLFRGTLEPVEKALKDAKLDKSSIHDVVLVGGSTRIPKIQSMLQNFFCGKKLNLSINPDEAVAYGAAVQAAILSGEQHSKIQDVLLVDVAPLSLGIETAGGVMTKIIERNAKIPCKQSQTFTTYSDSQPAVTIQVYEGERAMTKDNNMLGRFDLTGIPPAPRGVPKIDVTFDIDANGILNVSAKENGTGRSKNIVIKNDKGRLSQAEIDRMVAEAERYKEEDDRQRERVAARNQLETYIFNVKQAVDDAGDKLSAQDKESVRNDCEAALRWLDNNTLAEKDEFQQKLKDLQQVCSPVMSKIHATGSQQYSQPNRSGPTVEEVD

Similarity

Belongs to the heat shock protein 70 family.

Uniprot

F8UN43   T1SBT5   A0A2H1W9K6   A0A0S1MMB1   A0A212FCV0   C8CCR3   + More
E3UVB8   T1SBT1   T1SC34   F8UN42   A0A2C9PHS1   T1SBT7   A6P319   E7D2J5   A0A212F995   Q2F683   C4P3P9   C0LRA8   A0A2W1BCN7   B1A8R7   A0A0L7KZH8   E0A3F7   J7IL09   C6KEP2   Q6L6T3   A0A194QJ85   D9D840   E0A3F8   Q0KKB4   E0A3F6   A5A3D9   J7FIB4   U3KZM6   Q86GI6   I3WA85   I3WA86   A9CSM0   J7IIA2   J7I5M9   E9LK30   E9LK31   A0A068F6C3   A0A346THN6   E2FZ92   A0A023F628   A0A023F633   A0A1B6KRC2   T1I0D9   A0A1Z1JNE2   A0A139WDJ1   J7G295   A0A1Z1JMY7   E2GLM4   N6TG46   A0A1L2EC59   D6QX79   A5HTV3   A0A1S5VZD3   D1CSA1   B5TGR3   D6WU59   A0A346THM2   A0A1S5VZG2   A0A212F282   D1LWU2   B5AN02   A0A2A4J9S3   A0A1S3D948   B5TGQ9   J3JWS1   K9MV11   A0A023F600   A0A345W860   A0A0B4L040   A0A1S3DAN2   A0A1Z1JMY1   F5BYS7   A0A224XGB7   A0A1S3D964   A0A034V9V9   U3GPH7   B4K7C9   A0A1B0CP15   A0A076U3V0   F1C382   A0A2J7PG88   A0A2P0XIF6   A0A1B6DH77   D9IFR8   A0A0K8W8R9   A0A146L5F1   D6WT72   A0A2J7PG27   F1C378   A0A172JCK2   Q5I939   A0A1W4XW28   D9IFR7   A0A165BK16   F1C379  

Pubmed

19121390    22118469    19782689    22957810    21362495    28756777    + More
19320763    26227816    26354079    17630658    18393570    25474469    28572631    18362917    19820115    23537049    28187833    22516182    23357950    25348373    17994087    21426536    26823975    17651238   

EMBL

BABH01042878    JF836795    AEI58997.1    JX680677    AGR84224.1    ODYU01007205    + More
SOQ49779.1    KT225460    ALL42052.1    AGBW02009136    OWR51575.1    GQ389711    ACV32640.1    HM593518    ADP37711.1    JX680676    AGR84223.1    JX680669    AGR84216.1    JF836794    AEI58996.1    KY930331    ATL76715.1    JX680670    AGR84217.1    AB035326    BAF69068.1    HQ012004    ADV03160.1    AGBW02009614    OWR50325.1    DQ311189    ABD36134.1    FJ862049    ACQ78180.1    FJ754276    ACN78407.1    KZ150133    PZC73022.1    EU430480    ABZ10939.1    JTDY01004123    KOB68565.1    HM370510    ADK94698.1    JQ693014    AFQ37587.1    GQ199477    ACS72236.1    AB179657    BAD18974.1    KQ458671    KPJ05577.1    GU945198    KR821069    ADI50267.1    ALL42057.1    HM370511    ADK94699.1    AB251895    BAF03555.1    HM370509    ADK94697.1    EF523381    ABP93405.1    JQ316541    AFO70209.1    JX678981    AFU06382.1    AY220911    AAO65964.1    JN863694    AFK93489.2    JN863695    AFK93490.1    AB325801    BAF95560.1    JQ693015    AFQ37588.1    JQ711194    AFQ33498.1    HQ107971    ADV58254.1    HQ107972    ADV58255.1    KJ701421    AID61521.1    MG265913    AXU24969.1    HM212645    ADK39311.1    GBBI01002050    JAC16662.1    GBBI01002049    JAC16663.1    GEBQ01026193    JAT13784.1    ACPB03005879    KY705383    ARW29609.1    KQ971357    KYB26038.1    JX112893    AFP54305.1    KY705385    ARW29611.1    HM367079    ADO14473.1    APGK01039299    KB740969    KB632230    ENN76738.1    ERL90377.1    KT003964    ANJ86404.1    HM013709    ADG03465.1    EF569673    ABQ39970.1    KX695168    AQP31338.1    DQ093385    ACZ52196.1    EU934244    ACH85201.1    KQ971352    EFA07459.1    EFA07510.1    MG265899    AXU24955.1    KX976473    AQP31363.1    AGBW02010783    OWR47855.1    GU074513    ACY71070.1    EU861391    ACF74975.2    NWSH01002246    PCG68835.1    EU934240    ACH85197.1    APGK01039300    BT127689    AEE62651.1    ENN76739.1    ERL90378.1    JX627810    AFX84560.1    GBBI01002093    JAC16619.1    MH042023    AXJ21598.1    KC620440    AHE77387.1    KY705384    ARW29610.1    JF421286    AEB52075.1    GFTR01007568    JAW08858.1    GAKP01020060    JAC38892.1    KF018929    AGT99186.1    CH933806    EDW14253.1    AJWK01021311    KJ867518    AIK01869.1    HQ184405    ADX42270.1    NEVH01025635    PNF15343.1    KY661325    AVA17412.1    GEDC01012328    JAS24970.1    HM141537    ADJ96610.1    GDHF01004711    JAI47603.1    GDHC01018490    GDHC01014986    JAQ00139.1    JAQ03643.1    KQ971354    EFA07173.1    PNF15290.1    HQ184404    ADX42267.1    KU311038    AMQ77288.1    AY842476    AAW32098.2    HM141536    ADJ96609.1    KU159184    AMX23517.1    ADX42268.1   

Proteomes

UP000005204    UP000007151    UP000037510    UP000053268    UP000015103    UP000007266    + More
UP000019118    UP000030742    UP000218220    UP000079169    UP000009192    UP000092461    UP000235965    UP000192223   

PRIDE

F8UN43    F8UN42    A6P319    Q2F683   

Pfam

PF00012   HSP70

Interpro

IPR013126   Hsp_70_fam        + More
IPR029047   HSP70_peptide-bd_sf       
IPR029048   HSP70_C_sf       
IPR018181   Heat_shock_70_CS       

SUPFAM

SSF100920   SSF100920        + More
SSF100934   SSF100934       

Gene 3D

1.20.1270.10     2.60.34.10    

ProteinModelPortal

F8UN43   T1SBT5   A0A2H1W9K6   A0A0S1MMB1   A0A212FCV0   C8CCR3   + More
E3UVB8   T1SBT1   T1SC34   F8UN42   A0A2C9PHS1   T1SBT7   A6P319   E7D2J5   A0A212F995   Q2F683   C4P3P9   C0LRA8   A0A2W1BCN7   B1A8R7   A0A0L7KZH8   E0A3F7   J7IL09   C6KEP2   Q6L6T3   A0A194QJ85   D9D840   E0A3F8   Q0KKB4   E0A3F6   A5A3D9   J7FIB4   U3KZM6   Q86GI6   I3WA85   I3WA86   A9CSM0   J7IIA2   J7I5M9   E9LK30   E9LK31   A0A068F6C3   A0A346THN6   E2FZ92   A0A023F628   A0A023F633   A0A1B6KRC2   T1I0D9   A0A1Z1JNE2   A0A139WDJ1   J7G295   A0A1Z1JMY7   E2GLM4   N6TG46   A0A1L2EC59   D6QX79   A5HTV3   A0A1S5VZD3   D1CSA1   B5TGR3   D6WU59   A0A346THM2   A0A1S5VZG2   A0A212F282   D1LWU2   B5AN02   A0A2A4J9S3   A0A1S3D948   B5TGQ9   J3JWS1   K9MV11   A0A023F600   A0A345W860   A0A0B4L040   A0A1S3DAN2   A0A1Z1JMY1   F5BYS7   A0A224XGB7   A0A1S3D964   A0A034V9V9   U3GPH7   B4K7C9   A0A1B0CP15   A0A076U3V0   F1C382   A0A2J7PG88   A0A2P0XIF6   A0A1B6DH77   D9IFR8   A0A0K8W8R9   A0A146L5F1   D6WT72   A0A2J7PG27   F1C378   A0A172JCK2   Q5I939   A0A1W4XW28   D9IFR7   A0A165BK16   F1C379  

PDB

5FPN     E-value=0,     Score=2200

KEGG

100862772    K03283 heat shock 70kDa protein 1/2/6/8 | (RefSeq) heat shock protein 68

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)
04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)
04144    Endocytosis - Bombyx mori (domestic silkworm)
04213    Longevity regulating pathway - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0016021   GO:0051085   GO:0051787   GO:0042623   GO:0016887   GO:0044183   GO:0034620   GO:0005737   GO:0042026   GO:0005829   GO:0034605   GO:0031072   GO:0051082   GO:0006986  

PANTHER

PTHR19375  

Length:

628

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00585

Exp number, first 60 AAs:

0.00043

Total prob of N-in:

0.00028

outside

1  -  628

 

 

Pi

227.731607

Theta

217.094278

Tajima's D

0.154279

CLR

0.630055

CSRT

0.419479026048698

Interpretation

Uncertain