Gene

KWMTBOMO12892  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012691

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_catalase-like_[Bombyx_mori]

Location

Bomo_Chr22(-):3644149-3645660      View in EpiBrowser

Full name

Catalase      

Location in the cell

Cytoplasmic   Reliability : 1.159 Peroxisomal   Reliability : 1.648

CDS

ATGTGTGGCTTATTCCAGGGACCCATCGGTATTATGACAACGAGTGCTGGATCGCCGATCGAACTCAAAGATGCGAGTAACACATTGAACTCAAATCTCATATTCAATGAATATTTTATGGATTCATTAACGCATTTAGTACGAGAGAGAATTCCCGAGAGGTTGGTGCATGCAAAAGCGGGTGGAGCATTCGGTTATTTTGAAGTTACGCATGATATTACGAGCATTTGTAAAGCCAAATTATTTAGTAAAATCGGAAAGAAAACCCCAGTGGCAGCAAGATTTTCTCCAGTGGTAGTCGAAAGGGGAGGTACTGACACTTCAAGAGATGCGCGCGGGTTCGCCATTAAATTTTACACTGAAGACGGTAATTTTGATATCGTGGGATTCAATACCCCCATGTACGTTTACAAAGATCCTCTGCTTTTTCCGACATTTGTACGAGCTCAAAAACGAAATCCAGCTACTAATTTAATAGACGGTAATACGCTGTGGGATTTTTTGACGTTGCAACCGGAAAGCTTGCATATGTTTTTGCTTGTATTTGGGGATAGAGGCATACCAGATGGTTACAGGCATATGCCAGGGTTTGGCATTCACACTTATCAAGTTGTCAATGAGAGTGGAGAGAAGCACTTTGTTAGATTTCATTTTATTCCTGACGCTGGTATTAAAAATCTAAACTCTAAACAAGCACAGAAAATATCCGGTATTGATCCAGATTACGCCACCAGAGATTTGTATAATGCGATAGGAAAGGGTAAATTTCCGAGCTGGTCTGTCAGTATCCAGATATTGACATTAGACGATGTCAAAAATGCACAATTCGATGTTTTTGACGTGACAAAAATATTACCTCAAGATGAATTTCCCCTAAAGCCACTCGGTCGTTTTGTTTTGAACAAAAATCCGACGAACTATTTCGCGGAAATAGAACAGTTGGCGTATAGCCCAGCAAATCTTGTGCCGGGCATTTTGGGTGGACCGGACAAAGTATTCGAAGCTAGACGCTTAGCTTACAGAGACGCTCAATATTACCGGTTAGGTGCTAACTTTAATAAAATACCGGTAAATTGTCCGATTCAAAATCACGTACTTGCTTACAATCGCGATGGTCGACCTCCCGTTAAGGATAATGGTAAAGATACCCCCAATTATTATCCTAACACGTTCAATGGACCGGTGCCTTACAAAGATGAGAATAGAGTTGACCTTATCGAGATATACCAAGATGATCCTAACAACTTCGATCAGGCTAGAGAGCTGTATATGAACGAAATGACGAAAGAGGAACGAAGCAGACTTGTCGAAAACATTCTGTATAGTCTTGGTGGTGCTATCGAAGAATTGCAGGATAGAGCAGTGAAATTTTTCACAATCATACACCCAGATCTTGGTTACAGAATATCTCAAGGTTTAAAAGTGAACCGAACGTCGTACTACTGGGATGATGAATAG

Protein

MCGLFQGPIGIMTTSAGSPIELKDASNTLNSNLIFNEYFMDSLTHLVRERIPERLVHAKAGGAFGYFEVTHDITSICKAKLFSKIGKKTPVAARFSPVVVERGGTDTSRDARGFAIKFYTEDGNFDIVGFNTPMYVYKDPLLFPTFVRAQKRNPATNLIDGNTLWDFLTLQPESLHMFLLVFGDRGIPDGYRHMPGFGIHTYQVVNESGEKHFVRFHFIPDAGIKNLNSKQAQKISGIDPDYATRDLYNAIGKGKFPSWSVSIQILTLDDVKNAQFDVFDVTKILPQDEFPLKPLGRFVLNKNPTNYFAEIEQLAYSPANLVPGILGGPDKVFEARRLAYRDAQYYRLGANFNKIPVNCPIQNHVLAYNRDGRPPVKDNGKDTPNYYPNTFNGPVPYKDENRVDLIEIYQDDPNNFDQARELYMNEMTKEERSRLVENILYSLGGAIEELQDRAVKFFTIIHPDLGYRISQGLKVNRTSYYWDDE

Description

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic Activity

2 H2O2 = 2 H2O + O2

Cofactor

heme

Subunit

Homotetramer.

Similarity

Belongs to the catalase family.

Keywords

Complete proteome   Direct protein sequencing   Heme   Hydrogen peroxide   Iron   Metal-binding   Oxidoreductase   Peroxidase   Peroxisome   Reference proteome  

Feature

chain  Catalase

Uniprot

H9JT29   H9JY90   A0A0N0PDT6   A0A194Q886   A0A0L7L1C7   A0A2H1V005   + More
A0A2A4JP02   A0A212F4X0   A0A3S2LYY1   H9JY91   A0A0L7L5S1   A0A212F4W1   A0A2A4JNL0   A0A2H1W235   A0A0L7KXM9   A0A2R2PTF8   A0A1V0QH47   A0A2T7P5M1   T1E1G6   J9HGP0   A0A194PRI4   G5CDD8   A0A2H1WQ68   A0A1L8EEQ5   B0WIN9   A0A0L0C8Y9   A0A1S4JIQ3   A0A1L8EEC3   T1FMR4   A0A2Z4N440   S4PA78   A0A2S2R3I9   A0A2S2PUK2   B3M869   A0A2C9JBA3   B3NHN7   A0A2H8TEJ7   I4DMH7   H9U5T8   A0A1I8PLT9   A0A212F436   A0A182GFN9   A0A023EUF0   A0A1I8PLM9   A0A0M4EK05   A0A1Q3FPN2   A0A194QVH0   A0A034WTI4   A0A0C9Q530   A0A084WKX1   Q16J86   A0A3R7QHC4   B4J1T4   A0A1I8MF15   B2XQY0   A0EJ86   H9BEW3   A0A2I0MHZ3   A0A091Q0T0   A0A182RFS2   A0A1A9V5X9   B3N7D9   A0A1S3JUG5   B4IFV9   A0A1B0A740   A0A0P4VT66   A0A2S0RQP9   T1PCG9   A0A0K8VAH0   A0A091TEG0   T2FDK5   A0A182MJ06   A0A286RZM9   B4QPW5   A0A1W7RAT2   A0A0S1SHH8   A0A3B0K782   A0A094NRL4   A0A091UW02   A0A1V4JPF3   B4LFX2   D3TRU3   A0A091N9S2   B4HYQ5   B4Q788   Q9VLI6   A0A1L7LQD2   C0MII7   A0A3B0JH35   J9JLF8   H9ITX1   A0A0A1WYM5   A0A0K8TMT3   A0A093C6Q8   A0A0N9E6Y9   A0A091U2I5   H8XYP6   A0A1W4UPD3   A0A210QN80   P17336  

EC Number

1.11.1.6

Pubmed

19121390    26354079    26227816    22118469    24330624    17510324    + More
26108605    23254933    23622113    17994087    15562597    22651552    26483478    24945155    25348373    24438588    25315136    18353680    17189829    23371554    27129103    22936249    20353571    10731132    12537568    12537572    12537573    12537574    16110336    16951084    17569856    17569867    19126864    26109357    26109356    26760975    28076409    25830018    26369729    22293093    28812685    8660653    2362827    12537569    8500545   

EMBL

BABH01030664    BABH01042963    KQ460041    KPJ18348.1    KQ459324    KPJ01604.1    + More
JTDY01003585    KOB69303.1    ODYU01000045    SOQ34149.1    NWSH01000997    PCG73173.1    AGBW02010296    OWR48787.1    RSAL01000108    RVE47224.1    BABH01042965    BABH01042966    JTDY01002827    KOB70646.1    OWR48788.1    PCG73174.1    ODYU01005857    SOQ47155.1    JTDY01004753    KOB67801.1    KX079633    KX065288    ANA84065.1    KY701971    ARE67828.1    PZQS01000006    PVD28719.1    GALA01001689    JAA93163.1    CH478024    EJY58037.1    KQ459594    KPI96061.1    JN051294    AEP40969.1    ODYU01010180    SOQ55126.1    GFDG01001766    JAV17033.1    DS231951    EDS28616.1    JRES01000836    KNC27864.1    GFDG01001805    JAV16994.1    AMQM01003159    KB096023    ESO09072.1    MG397135    AWX63639.1    GAIX01003369    JAA89191.1    GGMS01015355    MBY84558.1    GGMR01020510    MBY33129.1    CH902618    EDV41008.1    CH954178    EDV51832.1    GFXV01000706    MBW12511.1    AK402495    BAM19117.1    JQ663444    AFG31725.1    AGBW02010446    OWR48497.1    JXUM01010672    JXUM01010673    KQ560314    KXJ83094.1    GAPW01001047    JAC12551.1    CP012525    ALC44426.1    GFDL01005612    JAV29433.1    KQ461108    KPJ09319.1    GAKP01001864    JAC57088.1    GBYB01009173    JAG78940.1    ATLV01024156    KE525350    KFB50865.1    EAT34333.1    QCYY01001316    ROT78899.1    CH916366    EDV98014.1    EU102287    ABW82155.1    DQ104435    AAZ50618.1    JQ009332    AFC98367.1    AKCR02000011    PKK29303.1    KK684122    KFQ13842.1    CH954177    EDV58290.1    CH480834    EDW46546.1    GDKW01001433    JAI55162.1    MF979105    AWA45968.1    KA645638    AFP60267.1    GDHF01016433    JAI35881.1    KK449746    KFQ72844.1    KF367466    AGV76059.1    AXCM01002921    AXCM01002922    MF737386    ASX95436.1    CM000363    CM002912    EDX10993.1    KMZ00447.1    GFAH01000134    JAV48255.1    KR908786    ALM09355.1    OUUW01000006    SPP81496.1    KL287880    KFZ69041.1    KL410118    KFQ94150.1    LSYS01006880    OPJ74063.1    CH940647    EDW70371.1    CCAG010022811    EZ424145    ADD20421.1    KK826694    KFP73266.1    CH480818    EDW52185.1    CM000361    CM002910    EDX04282.1    KMY89138.1    AE014134    AY058324    AM294019    AM294020    AM294021    AM294022    AM294024    AM294025    AM294026    AM294027    FM245150    FM245151    FM245152    FM245153    FM245155    FM245156    FM245157    FM245158    AAF52704.1    AAL13553.1    CAL25923.1    CAL25924.1    CAL25925.1    CAL25926.1    CAL25928.1    CAL25929.1    CAL25930.1    CAL25931.1    CAR93076.1    CAR93077.1    CAR93078.1    CAR93079.1    CAR93081.1    CAR93082.1    CAR93083.1    CAR93084.1    FX983163    BAV93783.1    FM245159    CAR93085.1    SPP81495.1    ABLF02017906    BABH01007112    GBXI01010123    JAD04169.1    GDAI01002147    JAI15456.1    KL459319    KFV11595.1    KR072552    ALF39394.1    KK414861    KFQ84984.1    HQ668089    AET34916.1    NEDP02002733    OWF50197.1    U00145    X52286    AE014296    AY084154   

Proteomes

UP000005204    UP000053240    UP000053268    UP000037510    UP000218220    UP000007151    + More
UP000283053    UP000245119    UP000008820    UP000002320    UP000037069    UP000015101    UP000007801    UP000076420    UP000008711    UP000095300    UP000069940    UP000249989    UP000092553    UP000030765    UP000283509    UP000001070    UP000095301    UP000053872    UP000075900    UP000078200    UP000085678    UP000001292    UP000092445    UP000075883    UP000000304    UP000268350    UP000053283    UP000190648    UP000008792    UP000092444    UP000000803    UP000007819    UP000192221    UP000242188   

PRIDE

H9JT29    H9JY90    H9JY91    Q9VLI6    H9ITX1    P17336    + More

Pfam

PF06628   Catalase-rel        + More
PF00199   Catalase

Interpro

IPR020835   Catalase_sf        + More
IPR011614   Catalase_core       
IPR024711   Catalase_clade1/3       
IPR024708   Catalase_AS       
IPR018028   Catalase       
IPR010582   Catalase_immune_responsive       
IPR037060   Catalase_core_sf       
IPR040333   Catalase_3       
IPR002226   Catalase_haem_BS       
IPR019786   Zinc_finger_PHD-type_CS       
IPR019787   Znf_PHD-finger       
IPR013083   Znf_RING/FYVE/PHD       
IPR001965   Znf_PHD       
IPR011011   Znf_FYVE_PHD       

SUPFAM

SSF56634   SSF56634        + More
SSF57903   SSF57903       

Gene 3D

2.40.180.10     3.30.40.10    

CDD

cd08156  catalase_clade_3

ProteinModelPortal

H9JT29   H9JY90   A0A0N0PDT6   A0A194Q886   A0A0L7L1C7   A0A2H1V005   + More
A0A2A4JP02   A0A212F4X0   A0A3S2LYY1   H9JY91   A0A0L7L5S1   A0A212F4W1   A0A2A4JNL0   A0A2H1W235   A0A0L7KXM9   A0A2R2PTF8   A0A1V0QH47   A0A2T7P5M1   T1E1G6   J9HGP0   A0A194PRI4   G5CDD8   A0A2H1WQ68   A0A1L8EEQ5   B0WIN9   A0A0L0C8Y9   A0A1S4JIQ3   A0A1L8EEC3   T1FMR4   A0A2Z4N440   S4PA78   A0A2S2R3I9   A0A2S2PUK2   B3M869   A0A2C9JBA3   B3NHN7   A0A2H8TEJ7   I4DMH7   H9U5T8   A0A1I8PLT9   A0A212F436   A0A182GFN9   A0A023EUF0   A0A1I8PLM9   A0A0M4EK05   A0A1Q3FPN2   A0A194QVH0   A0A034WTI4   A0A0C9Q530   A0A084WKX1   Q16J86   A0A3R7QHC4   B4J1T4   A0A1I8MF15   B2XQY0   A0EJ86   H9BEW3   A0A2I0MHZ3   A0A091Q0T0   A0A182RFS2   A0A1A9V5X9   B3N7D9   A0A1S3JUG5   B4IFV9   A0A1B0A740   A0A0P4VT66   A0A2S0RQP9   T1PCG9   A0A0K8VAH0   A0A091TEG0   T2FDK5   A0A182MJ06   A0A286RZM9   B4QPW5   A0A1W7RAT2   A0A0S1SHH8   A0A3B0K782   A0A094NRL4   A0A091UW02   A0A1V4JPF3   B4LFX2   D3TRU3   A0A091N9S2   B4HYQ5   B4Q788   Q9VLI6   A0A1L7LQD2   C0MII7   A0A3B0JH35   J9JLF8   H9ITX1   A0A0A1WYM5   A0A0K8TMT3   A0A093C6Q8   A0A0N9E6Y9   A0A091U2I5   H8XYP6   A0A1W4UPD3   A0A210QN80   P17336  

PDB

1QQW     E-value=1.7661e-132,     Score=1211

KEGG

101743673    K03781 catalase [EC:1.11.1.6] | (RefSeq) catalase-like

PATHWAY

00380    Tryptophan metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)
04213    Longevity regulating pathway - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0004096   GO:0020037   GO:0006979   GO:0042744   GO:0042542   GO:0005777   GO:0038001   GO:0036335   GO:0034976   GO:0048167   GO:0035206   GO:0003007   GO:0072593   GO:0008340   GO:0007568   GO:0016209   GO:0010181   GO:0016040   GO:0045181   GO:0050660   GO:0008152   GO:0016491   GO:0015930   GO:0055114  

PANTHER

PTHR11465  

Subcellular location

Peroxisome  

Length:

485

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0016

Exp number, first 60 AAs:

0.00083

Total prob of N-in:

0.00039

outside

1  -  485

 

 

Pi

5.610854

Theta

37.642259

Tajima's D

-1.553353

CLR

0.488105

CSRT

0.0539973001349933

Interpretation

Uncertain