Gene

KWMTBOMO12891  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014510

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_catalase-like_[Bombyx_mori]

Location

Bomo_Chr22(-):3609331-3612370      View in EpiBrowser

Full name

Catalase      

Location in the cell

Mitochondrial   Reliability : 1.364 Peroxisomal   Reliability : 1.083

CDS

ATGTTACGTTTGACGATAGCGTTGCTTGCGATGGTCGCGGTGGCAAAAACTGGGAACGAGCCAGCGCCGGCAGCCCAGCAGATAGTCGCGTTCAAACAGAGAACATCGGGGCCCATCGGTATTATGACAACGAGTGCTGGATCGCCAATCGAACTCAAAGATGCGAGTAGCACATTGAACTCAAATCTCATATTGAATGAATATTTTATGGATTCATTAACTCATATAGTAAGAGAGAGGATTCCCGAGAGGTTGGTGCATGCAAAAGCGGCTGGAGCATTCGGTTATTTTGAGGTTACGCATGATATTAAGAATATTTGTAAAGCCAAATTATTTAGTAAAATAGGAAAGAAAACTCCAGTGGCAGCAAGATTTTCTCCGGTGATAGTCCAAAGAGGAGGTACTGATACTTCAAGAGATGCGCGCGGGTTTGCTATTAAATTTTACACTGAAGACGGTAATTTTGATATCGTGGGATTCAATACGCCCATGTACGCGTACAAAGATCCACTGCTTTTTTCATCATTTGTGCGAGCTCTAAAACGAAATCCAGCTACTAATTTAGTAGACGGTAATACGCTATGGGACTTTTTGACGTTGCAACCGGAGAACTTACATATGTTTTTGCTCGTATTTGGGGATAGAGGTGTGCCAGATGGTTACAGGCATATGCCAGGGTTTAGCATTCAAACCTATCAAGTTGTGAATGAGAGTGGAGAGAAGCACTTTGTTAGATTTCATTTTATTCCTGACGCTGGCATAAAAAATCTAAACTCTAAACAAGCACAGAAAATATCCGGTATCGATCCAGATTACGCCACCAGAGATTTGTATAATGCGATAGGAAAGGGTAAATTTCCGAGCTGGTCTGTCAGTATCCAGATATTGACATTAGACGATGTGAAAAATGCAAAATTCGATGTTTTTGACGTGACGAAAGTATTACCCCAAGATGAATTTCCCCTAAAACCACTCGGTCGTTTGGTTTTGAACAAAAATCCGACGAACTATTTTGCAGAAGTAGAACAGTTGGCGTTTAACCCAGCAAATCTTGTGCCGGGCATTTTGGGAGGACCGACCAAAATTTTCGAAGCAAGACGTTTAGCTTACAGAGACGCTCAATATTACCGGTTAGGTGCTAACTTTAATAAAATACCGGTAAATTGTCCGATTCAAAATCACGTACTTGCTTACAATCGCGATGGTCGACCTCCCGTTAAGGATAATGGTAAAGATACCCCCAATTATTATCCTAACACGTTCAATGGACCGGTGCCTTACAAAGATGAGAATAGAGTTGACCTTATCGAGATATACCAAGATGATCCTAACAACTTCGATCAGGCTAGAGAGCTGTATATGAACGAAATGACGAAAGAGGAACGAAGCAGACTTGTCGAAAACATTCTGTATAGTCTTGGTGGTGCTATCGAAGAATTGCAGGATAGAGCAGTGAAAATTTTCACAATCATACACCCAGATCTTGGTTACAGAATATCTCAAGGTCTAAAAGTGAACCGAACGTCGTACTACCGGGATGATGAATGGCTTAATAATAATTAG

Protein

MLRLTIALLAMVAVAKTGNEPAPAAQQIVAFKQRTSGPIGIMTTSAGSPIELKDASSTLNSNLILNEYFMDSLTHIVRERIPERLVHAKAAGAFGYFEVTHDIKNICKAKLFSKIGKKTPVAARFSPVIVQRGGTDTSRDARGFAIKFYTEDGNFDIVGFNTPMYAYKDPLLFSSFVRALKRNPATNLVDGNTLWDFLTLQPENLHMFLLVFGDRGVPDGYRHMPGFSIQTYQVVNESGEKHFVRFHFIPDAGIKNLNSKQAQKISGIDPDYATRDLYNAIGKGKFPSWSVSIQILTLDDVKNAKFDVFDVTKVLPQDEFPLKPLGRLVLNKNPTNYFAEVEQLAFNPANLVPGILGGPTKIFEARRLAYRDAQYYRLGANFNKIPVNCPIQNHVLAYNRDGRPPVKDNGKDTPNYYPNTFNGPVPYKDENRVDLIEIYQDDPNNFDQARELYMNEMTKEERSRLVENILYSLGGAIEELQDRAVKIFTIIHPDLGYRISQGLKVNRTSYYRDDEWLNNN

Description

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic Activity

2 H2O2 = 2 H2O + O2

Cofactor

heme

Subunit

Homotetramer.

Similarity

Belongs to the catalase family.

Keywords

Complete proteome   Direct protein sequencing   Heme   Hydrogen peroxide   Iron   Metal-binding   Oxidoreductase   Peroxidase   Peroxisome   Reference proteome  

Feature

chain  Catalase

Uniprot

H9JY90   H9JT29   H9JY91   A0A0N0PDT6   A0A194Q886   A0A0L7L1C7   + More
A0A2H1V005   A0A2A4JP02   A0A3S2LYY1   A0A212F4X0   A0A0L7L5S1   A0A212F4W1   A0A2A4JNL0   A0A2H1W235   A0A2R2PTF8   A0A1V0QH47   A0A0L7KXM9   A0A2T7P5M1   T1FMR4   A0A194PRI4   A0A2H1WQ68   A0A1L8EEQ5   G5CDD8   A0A2Z4N440   H9U5T8   S4PA78   A0A1L8EEC3   A0A2S0RQP9   A0A1I8PLT9   J9HGP0   A0A212F436   A0A1S3JUG5   B3M869   I4DMH7   A0A0L0C8Y9   A0A3R7QHC4   A0A194QVH0   B3NHN7   T1E1G6   B2XQY0   H8XYP6   Q6R2J1   B4KEW9   A0A3B0K782   A0A286RZM9   H9BEW3   A0A034WTI4   A0A0C9Q530   A0A3B0JH35   A0A1I8MF15   A0A0M3QTJ1   A0A182GFN9   A0A0M4EF65   A0A0L7KZY0   T2FDK5   A0A0K8VAH0   A0A023EUF0   B3N7D9   T1PCG9   H9ITX1   A0A0S1SHH8   A0A0M4EK05   B4M9N1   A0A1I8PLM9   B4HYQ5   B4Q788   A0A0A1WYM5   A0A1W4UPD3   Q9VLI6   B4IFV9   A0A0K8TMT3   M9UWB5   A0A067RLP1   C0MII7   A0A1L7LQD2   B4J1T4   A0A3B0JYK5   A0EJ86   A0A0P4VT66   Q68AP5   N6UDL6   K4N1L2   B4N4F5   B4QPW5   A0A2S2PUK2   Q16J86   B3MLZ0   A0A2C9JBA3   A0AMY5   B4NXH2   A0A1S4JIQ3   B0WIN9   A0A1Q3FPN2   Q29JU0   B4GJ58   P17336   A0A2S2R3I9   A0A2H8TEJ7   Q2M0D6  

EC Number

1.11.1.6

Pubmed

19121390    26354079    26227816    22118469    23254933    23622113    + More
17510324    17994087    22651552    26108605    24330624    18353680    22293093    15325332    23142216    25348373    25315136    26483478    24945155    22936249    25830018    10731132    12537568    12537572    12537573    12537574    16110336    16951084    17569856    17569867    19126864    26109357    26109356    26369729    26457718    24845553    26760975    28076409    17189829    27129103    15763464    23537049    15562597    17550304    15632085    8660653    2362827    12537569    8500545   

EMBL

BABH01042963    BABH01030664    BABH01042965    BABH01042966    KQ460041    KPJ18348.1    + More
KQ459324    KPJ01604.1    JTDY01003585    KOB69303.1    ODYU01000045    SOQ34149.1    NWSH01000997    PCG73173.1    RSAL01000108    RVE47224.1    AGBW02010296    OWR48787.1    JTDY01002827    KOB70646.1    OWR48788.1    PCG73174.1    ODYU01005857    SOQ47155.1    KX079633    KX065288    ANA84065.1    KY701971    ARE67828.1    JTDY01004753    KOB67801.1    PZQS01000006    PVD28719.1    AMQM01003159    KB096023    ESO09072.1    KQ459594    KPI96061.1    ODYU01010180    SOQ55126.1    GFDG01001766    JAV17033.1    JN051294    AEP40969.1    MG397135    AWX63639.1    JQ663444    AFG31725.1    GAIX01003369    JAA89191.1    GFDG01001805    JAV16994.1    MF979105    AWA45968.1    CH478024    EJY58037.1    AGBW02010446    OWR48497.1    CH902618    EDV41008.1    AK402495    BAM19117.1    JRES01000836    KNC27864.1    QCYY01001316    ROT78899.1    KQ461108    KPJ09319.1    CH954178    EDV51832.1    GALA01001689    JAA93163.1    EU102287    ABW82155.1    HQ668089    AET34916.1    AY518322    JX162772    AAR99908.1    AFM68912.1    CH933807    EDW11938.1    OUUW01000006    SPP81496.1    MF737386    ASX95436.1    JQ009332    AFC98367.1    GAKP01001864    JAC57088.1    GBYB01009173    JAG78940.1    SPP81495.1    CP012523    ALC39003.1    JXUM01010672    JXUM01010673    KQ560314    KXJ83094.1    ALC39005.1    JTDY01004115    KOB68584.1    KF367466    AGV76059.1    GDHF01016433    JAI35881.1    GAPW01001047    JAC12551.1    CH954177    EDV58290.1    KA645638    AFP60267.1    BABH01007112    KR908786    ALM09355.1    CP012525    ALC44426.1    CH940654    EDW57907.1    CH480818    EDW52185.1    CM000361    CM002910    EDX04282.1    KMY89138.1    GBXI01010123    JAD04169.1    AE014134    AY058324    AM294019    AM294020    AM294021    AM294022    AM294024    AM294025    AM294026    AM294027    FM245150    FM245151    FM245152    FM245153    FM245155    FM245156    FM245157    FM245158    AAF52704.1    AAL13553.1    CAL25923.1    CAL25924.1    CAL25925.1    CAL25926.1    CAL25928.1    CAL25929.1    CAL25930.1    CAL25931.1    CAR93076.1    CAR93077.1    CAR93078.1    CAR93079.1    CAR93081.1    CAR93082.1    CAR93083.1    CAR93084.1    CH480834    EDW46546.1    GDAI01002147    JAI15456.1    KC485002    AGJ70294.1    KK852549    KDR21530.1    FM245159    CAR93085.1    FX983163    BAV93783.1    CH916366    EDV98014.1    OUUW01000002    SPP76188.1    DQ104435    AAZ50618.1    GDKW01001433    JAI55162.1    AB164195    BAD38853.1    APGK01039325    KB740969    KB632230    ENN76752.1    ERL90392.1    JX513905    AFV36369.1    CH964095    EDW79029.1    CM000363    CM002912    EDX10993.1    KMZ00447.1    GGMR01020510    MBY33129.1    EAT34333.1    CH902620    EDV31818.1    AM294023    CAL25927.1    CM000157    EDW88563.1    DS231951    EDS28616.1    GFDL01005612    JAV29433.1    CH379062    EAL32871.1    CH479184    EDW37372.1    U00145    X52286    AE014296    AY084154    GGMS01015355    MBY84558.1    GFXV01000706    MBW12511.1    CH379069    EAL30998.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000037510    UP000218220    UP000283053    + More
UP000007151    UP000245119    UP000015101    UP000095300    UP000008820    UP000085678    UP000007801    UP000037069    UP000283509    UP000008711    UP000009192    UP000268350    UP000095301    UP000092553    UP000069940    UP000249989    UP000008792    UP000001292    UP000000304    UP000192221    UP000000803    UP000027135    UP000001070    UP000019118    UP000030742    UP000007798    UP000076420    UP000002282    UP000002320    UP000001819    UP000008744   

PRIDE

H9JY90    H9JT29    H9JY91    H9ITX1    Q9VLI6    Q68AP5    + More
A0AMY5    P17336   

Pfam

PF00199   Catalase        + More
PF06628   Catalase-rel

Interpro

IPR024708   Catalase_AS        + More
IPR018028   Catalase       
IPR024711   Catalase_clade1/3       
IPR020835   Catalase_sf       
IPR011614   Catalase_core       
IPR037060   Catalase_core_sf       
IPR010582   Catalase_immune_responsive       
IPR040333   Catalase_3       
IPR002226   Catalase_haem_BS       
IPR019786   Zinc_finger_PHD-type_CS       
IPR019787   Znf_PHD-finger       
IPR013083   Znf_RING/FYVE/PHD       
IPR001965   Znf_PHD       
IPR011011   Znf_FYVE_PHD       

SUPFAM

SSF56634   SSF56634        + More
SSF57903   SSF57903       

Gene 3D

2.40.180.10     3.30.40.10    

CDD

cd08156  catalase_clade_3

ProteinModelPortal

H9JY90   H9JT29   H9JY91   A0A0N0PDT6   A0A194Q886   A0A0L7L1C7   + More
A0A2H1V005   A0A2A4JP02   A0A3S2LYY1   A0A212F4X0   A0A0L7L5S1   A0A212F4W1   A0A2A4JNL0   A0A2H1W235   A0A2R2PTF8   A0A1V0QH47   A0A0L7KXM9   A0A2T7P5M1   T1FMR4   A0A194PRI4   A0A2H1WQ68   A0A1L8EEQ5   G5CDD8   A0A2Z4N440   H9U5T8   S4PA78   A0A1L8EEC3   A0A2S0RQP9   A0A1I8PLT9   J9HGP0   A0A212F436   A0A1S3JUG5   B3M869   I4DMH7   A0A0L0C8Y9   A0A3R7QHC4   A0A194QVH0   B3NHN7   T1E1G6   B2XQY0   H8XYP6   Q6R2J1   B4KEW9   A0A3B0K782   A0A286RZM9   H9BEW3   A0A034WTI4   A0A0C9Q530   A0A3B0JH35   A0A1I8MF15   A0A0M3QTJ1   A0A182GFN9   A0A0M4EF65   A0A0L7KZY0   T2FDK5   A0A0K8VAH0   A0A023EUF0   B3N7D9   T1PCG9   H9ITX1   A0A0S1SHH8   A0A0M4EK05   B4M9N1   A0A1I8PLM9   B4HYQ5   B4Q788   A0A0A1WYM5   A0A1W4UPD3   Q9VLI6   B4IFV9   A0A0K8TMT3   M9UWB5   A0A067RLP1   C0MII7   A0A1L7LQD2   B4J1T4   A0A3B0JYK5   A0EJ86   A0A0P4VT66   Q68AP5   N6UDL6   K4N1L2   B4N4F5   B4QPW5   A0A2S2PUK2   Q16J86   B3MLZ0   A0A2C9JBA3   A0AMY5   B4NXH2   A0A1S4JIQ3   B0WIN9   A0A1Q3FPN2   Q29JU0   B4GJ58   P17336   A0A2S2R3I9   A0A2H8TEJ7   Q2M0D6  

PDB

1QQW     E-value=4.91325e-131,     Score=1199

KEGG

101746170    K03781 catalase [EC:1.11.1.6] | (RefSeq) catalase-like

PATHWAY

00380    Tryptophan metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)
04213    Longevity regulating pathway - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0004096   GO:0020037   GO:0046872   GO:0006979   GO:0042744   GO:0042542   GO:0005777   GO:0038001   GO:0036335   GO:0034976   GO:0048167   GO:0035206   GO:0003007   GO:0072593   GO:0008340   GO:0007568   GO:0016209   GO:0010181   GO:0016040   GO:0045181   GO:0050660   GO:0008152   GO:0016491   GO:0015930   GO:0055114  

PANTHER

PTHR11465  

Subcellular location

Peroxisome  

SignalP

Position:   1 - 15,         Likelihood:  0.966056

 

 

Length:

520

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00799999999999998

Exp number, first 60 AAs:

0.00651

Total prob of N-in:

0.00078

outside

1  -  520

 

 

Pi

376.971789

Theta

185.552462

Tajima's D

3.53878

CLR

0.379337

CSRT

0.994850257487126

Interpretation

Uncertain