Gene

KWMTBOMO12877

Pre Gene Modal

BGIBMGA012702

Annotation

Elongation_of_very_long_chain_fatty_acids_protein_6_[Papilio_xuthus]

Location

Bomo_Chr22(-):2855539-2902426      View in EpiBrowser

Full name

Elongation of very long chain fatty acids protein      

Alternative Name

Very-long-chain 3-oxoacyl-CoA synthase

Location in the cell

PlasmaMembrane   Reliability : 4.219

CDS

ATGTTCGTGCTATCGAAGCTTCCAGAACTCGGCGATACGGTTTTCATCGTCCTACGCAAGAAGCCGCTGATCTTCCTCCACTGGTACCACCACATCACGGTCCTGCTGTACACTTGGTATTCGTTCACTGAATACACATCGTCGGCGCGCTGGTTCGTCGTCATGAACTATTGTGTGCACAGCGTGATGTACTCGTACTACGCGCTCGTCAGTATGGGTAGGTACCCGCCGAAAGCCCTCGCCATGACCATCACCGTCCTCCAACTGACCCAGATGATCGTCGGCTGCGCGATCAACATCTGGGCGCACAACTACATGACGACCACTCCCTCGCACACGTGCCACATCAGCCAGATAAACATCAAGCTGTCGATGGCGATGTACTTCTCGTATTTCGTGCTTTTCGCTCAGTTCTTCTACAAAGCGTATCTGTCGCCGAAGAAAGGTAAGAAGGCCAAGGTGGAGCCCCCGAGTCCGACAAAACACGAGTCAATCAAGAATTACAACGGCTACCCGAGACAGAGGAACGGACTCGTGTCCACCCACTAG

Protein

MFVLSKLPELGDTVFIVLRKKPLIFLHWYHHITVLLYTWYSFTEYTSSARWFVVMNYCVHSVMYSYYALVSMGRYPPKALAMTITVLQLTQMIVGCAINIWAHNYMTTTPSHTCHISQINIKLSMAMYFSYFVLFAQFFYKAYLSPKKGKKAKVEPPSPTKHESIKNYNGYPRQRNGLVSTH

Catalytic Activity

a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA

Similarity

Belongs to the ELO family.

Feature

chain  Elongation of very long chain fatty acids protein

Uniprot

H9JT40   A0A2A4ITZ0   A0A194Q7V2   A0A194RC88   A0A2H1WNI3   A0A437BA05   + More
A0A212EVY4   A0A0L7L5V4   A0A182TI96   A0A182UM85   A0A182GFC0   A0A182PS01   A0A182KDZ3   A0A182WBX1   A0A182FFD5   A0A182WXB7   A0A182NIX0   A0A182SGF5   A0A182I4A6   W5JRV0   A0A182RU46   A0A182MRZ2   B0W865   A0A182Y7W3   A0A1Q3EU56   Q16K45   A0A2M4CSC8   A0A2M4CSK5   A0A1Q3EU49   A0A084WMK6   A0A2M3ZGN5   A0A2M4ANL8   A0NEU5   A0A182LKM7   A0A182Q2F7   A0A182JF31   A0A1Q3EU55   A0A0T6B571   A0A1A9XJW2   T1E2T6   B3M4F5   A0A1B0C6Q1   A0A1A9ZDX4   B4N3N2   A0A0L0CCK8   A0A1A9UKQ7   T1PDA6   A0A1A9WLL6   A0A0K8TTU1   W8BNJ9   A0A1B6JUT5   A0A1B0GF82   A0A1B6KG55   A0A1B0GJM8   A0A1L8DYA2   A0A0A1XGT7   B4LCZ0   A0A1B6FW47   B4J008   B4QMW6   A0A3B0JYJ2   Q29D49   A0A034W036   B4H7Z3   B4L9R7   A0A1L8DYF2   A0A0K8UH80   A0A0A9YMM0   A0A1W4UVX7   A0A0M4EBJ9   D3TQD9   A0A0K8T5K1   A0A1B6D0Y9   A0A0J9RWW9   B3NDJ3   B4PKB6   A0A1I8Q6M2   B4HJR2   A0A0N9E725   Q9VV87   D6WNP4   A0A336LP70   A0A0C9R1Z5   A0A3Q8FT76   A0A0J7KLD8   A0A1W4WHB5   A0A1J1HXA9   J3JVT6   A0A224XUX0   E2C9A0   A0A023FB42   A0A0N7Z8M3   R4G3B9   A0A2P8Y8F0   E2A0C7   A0A171AB57   E0W383   E9J1I3   A0A1S4N1H7   A0A026W486  

EC Number

2.3.1.199

Pubmed

19121390    26354079    22118469    26227816    26483478    20920257    + More
23761445    25244985    17510324    24438588    12364791    14747013    17210077    20966253    24330624    17994087    18057021    26108605    25315136    26369729    24495485    25830018    15632085    25348373    25401762    26823975    20353571    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18362917    19820115    22516182    23537049    20798317    25474469    27129103    29403074    20566863    21282665    24508170   

EMBL

BABH01030719    NWSH01008323    PCG62603.1    KQ459324    KPJ01617.1    KQ460416    + More
KPJ14895.1    ODYU01009904    SOQ54633.1    RSAL01000108    RVE47234.1    AGBW02012108    OWR45643.1    JTDY01002727    KOB70842.1    JXUM01000859    APCN01002295    ADMH02000355    ETN66851.1    AXCM01009103    AXCM01009104    DS231857    EDS38690.1    GFDL01016208    JAV18837.1    CH477978    EAT34657.1    GGFL01004066    MBW68244.1    GGFL01004067    MBW68245.1    GFDL01016206    JAV18839.1    ATLV01024481    KE525352    KFB51450.1    GGFM01006965    MBW27716.1    GGFK01009059    MBW42380.1    AAAB01008960    EAU76616.2    AXCN02000475    AXCN02000476    GFDL01016205    JAV18840.1    LJIG01009799    KRT82357.1    GALA01001005    JAA93847.1    CH902618    EDV40449.1    KPU78579.1    JXJN01026846    CH964095    EDW79237.1    JRES01000681    KNC29194.1    KA646772    AFP61401.1    GDAI01000238    JAI17365.1    GAMC01003870    JAC02686.1    GECU01021675    GECU01005043    JAS86031.1    JAT02664.1    CCAG010012770    GEBQ01029582    JAT10395.1    AJWK01021986    AJWK01021987    GFDF01002644    JAV11440.1    GBXI01011729    GBXI01008374    GBXI01004120    GBXI01003116    GBXI01000042    JAD02563.1    JAD05918.1    JAD10172.1    JAD11176.1    JAD14250.1    CH940647    EDW68851.1    GECZ01028707    GECZ01026305    GECZ01020106    GECZ01018437    GECZ01015612    GECZ01015596    GECZ01015344    GECZ01013867    GECZ01010604    GECZ01005574    GECZ01000493    JAS41062.1    JAS43464.1    JAS49663.1    JAS51332.1    JAS54157.1    JAS54173.1    JAS54425.1    JAS55902.1    JAS59165.1    JAS64195.1    JAS69276.1    CH916366    EDV96780.1    CM000363    EDX10758.1    OUUW01000012    SPP87135.1    CH379070    EAL30565.1    GAKP01011457    JAC47495.1    CH479219    EDW34783.1    CH933816    EDW17115.1    GFDF01002645    JAV11439.1    GDHF01032082    GDHF01026333    GDHF01026295    GDHF01025758    GDHF01024431    GDHF01022118    GDHF01020768    GDHF01003152    JAI20232.1    JAI25981.1    JAI26019.1    JAI26556.1    JAI27883.1    JAI30196.1    JAI31546.1    JAI49162.1    GBHO01018220    GBHO01010734    GBHO01010733    GDHC01021113    GDHC01017271    GDHC01010152    JAG25384.1    JAG32870.1    JAG32871.1    JAP97515.1    JAQ01358.1    JAQ08477.1    CP012525    ALC44854.1    EZ423641    ADD19917.1    GBRD01005008    GBRD01005007    GBRD01005006    GBRD01005004    JAG60814.1    GEDC01017968    GEDC01014321    JAS19330.1    JAS22977.1    CM002912    KMZ00088.1    CH954178    EDV52055.1    CM000159    EDW94814.1    CH480815    EDW41789.1    KR139924    ALF39428.1    AE014296    AF265296    AH009765    AF279257    AY061121    AAF49430.2    AAF75771.1    AAG02080.1    AAL28669.1    KQ971342    EFA03752.1    UFQT01000040    SSX18591.1    GBYB01000881    JAG70648.1    MG573188    AWJ25050.1    LBMM01005943    KMQ91077.1    CVRI01000035    CRK92661.1    APGK01037118    BT127354    KB740948    KB631899    AEE62316.1    ENN77236.1    ERL87005.1    GFTR01004647    JAW11779.1    GL453806    EFN75445.1    GBBI01000569    JAC18143.1    GDKW01002947    JAI53648.1    ACPB03017886    GAHY01002335    JAA75175.1    PYGN01000807    PSN40536.1    GL435569    EFN73130.1    GEMB01001284    JAS01870.1    DS235882    EEB20089.1    GL767671    EFZ13312.1    AAZO01007337    AAZO01007338    AAZO01007339    KK107455    EZA50416.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    + More
UP000037510    UP000075902    UP000075903    UP000069940    UP000075885    UP000075881    UP000075920    UP000069272    UP000076407    UP000075884    UP000075901    UP000075840    UP000000673    UP000075900    UP000075883    UP000002320    UP000076408    UP000008820    UP000030765    UP000007062    UP000075882    UP000075886    UP000075880    UP000092443    UP000007801    UP000092460    UP000092445    UP000007798    UP000037069    UP000078200    UP000095301    UP000091820    UP000092444    UP000092461    UP000008792    UP000001070    UP000000304    UP000268350    UP000001819    UP000008744    UP000009192    UP000192221    UP000092553    UP000008711    UP000002282    UP000095300    UP000001292    UP000000803    UP000007266    UP000036403    UP000192223    UP000183832    UP000019118    UP000030742    UP000008237    UP000015103    UP000245037    UP000000311    UP000009046    UP000053097   

PRIDE

H9JT40    Q9VV87   

Pfam

PF01151   ELO

Interpro

IPR002076   ELO_fam        + More
IPR030457   ELO_CS       
IPR036259   MFS_trans_sf       

SUPFAM

SSF103473   SSF103473       

ProteinModelPortal

H9JT40   A0A2A4ITZ0   A0A194Q7V2   A0A194RC88   A0A2H1WNI3   A0A437BA05   + More
A0A212EVY4   A0A0L7L5V4   A0A182TI96   A0A182UM85   A0A182GFC0   A0A182PS01   A0A182KDZ3   A0A182WBX1   A0A182FFD5   A0A182WXB7   A0A182NIX0   A0A182SGF5   A0A182I4A6   W5JRV0   A0A182RU46   A0A182MRZ2   B0W865   A0A182Y7W3   A0A1Q3EU56   Q16K45   A0A2M4CSC8   A0A2M4CSK5   A0A1Q3EU49   A0A084WMK6   A0A2M3ZGN5   A0A2M4ANL8   A0NEU5   A0A182LKM7   A0A182Q2F7   A0A182JF31   A0A1Q3EU55   A0A0T6B571   A0A1A9XJW2   T1E2T6   B3M4F5   A0A1B0C6Q1   A0A1A9ZDX4   B4N3N2   A0A0L0CCK8   A0A1A9UKQ7   T1PDA6   A0A1A9WLL6   A0A0K8TTU1   W8BNJ9   A0A1B6JUT5   A0A1B0GF82   A0A1B6KG55   A0A1B0GJM8   A0A1L8DYA2   A0A0A1XGT7   B4LCZ0   A0A1B6FW47   B4J008   B4QMW6   A0A3B0JYJ2   Q29D49   A0A034W036   B4H7Z3   B4L9R7   A0A1L8DYF2   A0A0K8UH80   A0A0A9YMM0   A0A1W4UVX7   A0A0M4EBJ9   D3TQD9   A0A0K8T5K1   A0A1B6D0Y9   A0A0J9RWW9   B3NDJ3   B4PKB6   A0A1I8Q6M2   B4HJR2   A0A0N9E725   Q9VV87   D6WNP4   A0A336LP70   A0A0C9R1Z5   A0A3Q8FT76   A0A0J7KLD8   A0A1W4WHB5   A0A1J1HXA9   J3JVT6   A0A224XUX0   E2C9A0   A0A023FB42   A0A0N7Z8M3   R4G3B9   A0A2P8Y8F0   E2A0C7   A0A171AB57   E0W383   E9J1I3   A0A1S4N1H7   A0A026W486  

KEGG

101741480    K10203 elongation of very long chain fatty acids protein 6 [EC:2.3.1.199] | (RefSeq) elongation of v

PATHWAY

00062    Fatty acid elongation - Bombyx mori (domestic silkworm)
01040    Biosynthesis of unsaturated fatty acids - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0102336   GO:0006633   GO:0102337   GO:0102756   GO:0016021   GO:0102338   GO:0042761   GO:0030148   GO:0019367   GO:0034626   GO:0009922   GO:0030176   GO:0034625   GO:0005741   GO:0007283   GO:0042759   GO:0030497   GO:0003743   GO:0005737   GO:0006413   GO:0015074   GO:0030429   GO:0004003   GO:0005634   GO:0006289   GO:0016286  

PANTHER

PTHR11157  

Length:

182

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

81.84954

Exp number, first 60 AAs:

29.23949

Total prob of N-in:

0.10097

POSSIBLE N-term signal

sequence

outside

1  -  23

TMhelix

24  -  41

inside

42  -  47

TMhelix

48  -  70

outside

71  -  79

TMhelix

80  -  102

inside

103  -  122

TMhelix

123  -  140

outside

141  -  182

 

 

Pi

206.581979

Theta

172.041462

Tajima's D

1.038005

CLR

0.135762

CSRT

0.675666216689165

Interpretation

Uncertain