Gene

KWMTBOMO12851  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012738

Annotation

PREDICTED:_peroxidase-like_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr22(-):1657215-1666368      View in EpiBrowser

Full name

Peroxidase      

Alternative Name

Chorion peroxidase

Location in the cell

Cytoplasmic   Reliability : 1.33

CDS

ATGTCTGCTGATGTAGTGTCTCTTCATGATACAGTTAAATATATTTTATGGAAGCCATATTGCTGTACGGCCAAAGGAAAAACTGATAGAGATTGTGTACAGAACAAAATACCTGATGATGACCCGGTGCACCGCTTCTCAGACATCAGGTGTCTGAACATGACGCGACCGGAGTCTTTTCAGTCCACTGGCTGTGTGAAAAATGGAACAGTTCCAGAAAGGATCGTATCGTCTACACCTCTGATCGACCTATCGATGATATATGGGAGCGTTTTAAAATCGCTACTGGCAAACGGAAGACTATTCAAAGGAGGCTTACTGAAGTATGAGAATTCTAATGGAAGAATCTGGCCTCCAAGTACCAAATCTCAAGCTAACCTTTGCTTTTTAAACGACAAGCCTAGAGAAACAAGATGTCATGCAACACCCGATATTGGTAGCAATACACTTGCTAGTGTCAATTTAATGAGTATTTGGTTTTGGAGGCACCACAATTTCATCGCGGAACAATTGGCAAAGATCAACCCGTGTTGGGATGACAATACGCTTTTTAATACAGCGAGAGACATAAATATCGCTGTAGCTCTACAGATATATCTTTATGAGCTGTTACCTCTTTTCTTGGGTCGTGACAATTTGGTCAGAGATGGTGTACTATCGCCTTCATTTGGATACAGAGATGCGTACAATCCTGAAATACTACCACAAGTTTCGCTCGAGTACCCGTTCGTCTTGCGATGGCTCCACAGCGTCCAGGAAGGCACCCTTAAAATGTACGACACAAAGGGATATTATCTCAAGCAGTATCCGATAGTGAACCTCACTTTGAGAACAGGCTTCTTCGATGTGGACAATAACATAGATTATATAACACAAGGAGCTTTCAGACAAGGCAGTGCTAATATTGACCATACAGCTGATCCTGATATCGTTGATATCGGCTTGGGTCCTCACCAAAGAGCATCAGATCTGATGACAAACGACATCTCCAAGAACAGATATTTTGGATTCCAGCCTTACGTTAAATACCACGAATTTTGCTTCGGTAAAACTATCAAGAAATGGGGAGACCTGGAAGGAGTAATTGACCCCGAGAGGATCGAAATACTCAAAGATTTGTACGAAGATGTTGAAGACATGGACCTCTTGGCCGGTATTTGGGTTGAGAGGCGCATTAAAGGTGGTTTCGTGCCGCCAACCTTCTACTGCTTGGTTGTGGAACAGCTAGTCCGCAATATTGTATCTGATAGACATTGGTACGAGAGCTCGAAAAGACCCAACGCCTTTAGTTTACAACAACTTTTCGAAATAAGGAAAGCTAGTATAGCTCGAATCCTTTGTGACGTTGGCGATAAGGTCACCGAAATACAGCCTCAAGCGTTCCTCAGACCGCATTCAAGAAACAGAATAAGTCGCTGCGAGAATATTCCCGGCATCGACTTCACAGCCTGGAAGGACTTCAAATGCAACGAACAGTACACCTGGCAATTATGCATAAAAGATACATTAAATCAATAA

Protein

MSADVVSLHDTVKYILWKPYCCTAKGKTDRDCVQNKIPDDDPVHRFSDIRCLNMTRPESFQSTGCVKNGTVPERIVSSTPLIDLSMIYGSVLKSLLANGRLFKGGLLKYENSNGRIWPPSTKSQANLCFLNDKPRETRCHATPDIGSNTLASVNLMSIWFWRHHNFIAEQLAKINPCWDDNTLFNTARDINIAVALQIYLYELLPLFLGRDNLVRDGVLSPSFGYRDAYNPEILPQVSLEYPFVLRWLHSVQEGTLKMYDTKGYYLKQYPIVNLTLRTGFFDVDNNIDYITQGAFRQGSANIDHTADPDIVDIGLGPHQRASDLMTNDISKNRYFGFQPYVKYHEFCFGKTIKKWGDLEGVIDPERIEILKDLYEDVEDMDLLAGIWVERRIKGGFVPPTFYCLVVEQLVRNIVSDRHWYESSKRPNAFSLQQLFEIRKASIARILCDVGDKVTEIQPQAFLRPHSRNRISRCENIPGIDFTAWKDFKCNEQYTWQLCIKDTLNQ

Description

Involved in the chorion hardening process, through protein cross-linking mediated by the formation of di- and tri-tyrosine bonds.

Catalytic Activity

2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O

Cofactor

heme b

Similarity

Belongs to the peroxidase family. XPO subfamily.

Keywords

Complete proteome   Disulfide bond   Glycoprotein   Heme   Hydrogen peroxide   Iron   Metal-binding   Oxidoreductase   Peroxidase   Reference proteome   Secreted   Signal  

Feature

chain  Peroxidase

Uniprot

A0A2A4IUC0   A0A2W1BYE5   A0A194Q9H2   A0A194RBC8   A0A194Q7Y0   A0A194RAP6   + More
I4DJ10   A0A194QDV6   A0A3S2NLC3   A0A2H1WGR9   A0A212ETD1   A0A2A4J7D3   A0A2W1BT67   A0A2H1W9U4   A0A2W1BT77   A0A2A4JI21   A0A088MGW5   A0A2H1W8U7   A0A2H1WAX3   A0A2H1WBG2   A0A2H1W4U4   H9JQT0   H9JT77   H9JT78   A0A437AS20   A0A2H1VUX0   A0A437ASV3   A0A0N0PED8   H9ISL1   A0A437AYB0   A0A3S2L850   A0A194Q3N0   A0A2A4IUP3   A0A2W1BQ93   A0A2A4JM77   A0A2W1BXH1   H9IT78   A0A3S2NMV9   A0A2A4IUD5   A0A2W1BS42   A0A2A4JMB0   A0A3S2M0V1   O96645   Q177U0   B4JHE0   Q16E76   A0A310SND6   A0A182FTE8   A0A182G7N2   B0XE84   B0WM28   W5JNS3   A0A182Q218   A0A182WXU8   A0A1S4H4U5   A0A182TM70   A0A182I5W9   A0A182KV49   A0A1W4VTT3   Q7QDZ3   A0A1A9W584   A0A182PRL2   A0A1Y9HDW6   A0A182KBY5   A0A1Y9H2I7   A0A182VL61   B4QWD4   B4IBN7   A0A0Q9WVU0   B4NJ86   B4KC82   A0A1A9Y5Z1   A0A0L0CRA6   A0A3B0JLT7   A0A1Y9IWB3   A0A182IZD9   B4G4K4   E1JIN0   Q01603   A0A182MPT8   A0A0B4KHM9   B5DWL8   B4M5J8   A0A2A3EU99   B3M2B4   A0A336MK45   B4PM93   A0A232F2X4   A0A2S2R1E6   A0A1B6MDD3   K7IYZ3   A0A088AE09   A0A0M4F792   D6WCM3  

EC Number

1.11.1.7

Pubmed

28756777    26354079    22651552    22118469    25191834    19121390    + More
11222958    17510324    17994087    26483478    20920257    23761445    12364791    20966253    26108605    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    1482687    15979004    14709175    15632085    17550304    28648823    20075255    18362917    19820115   

EMBL

NWSH01006580    PCG63355.1    KZ149907    PZC78257.1    KQ459324    KPJ01645.1    + More
KQ460416    KPJ14922.1    KPJ01647.1    KPJ14923.1    AK401278    BAM17900.1    KPJ01646.1    RSAL01000046    RVE50539.1    ODYU01008556    SOQ52260.1    AGBW02012596    OWR44740.1    NWSH01002854    PCG67434.1    PZC78258.1    ODYU01007226    SOQ49823.1    PZC78259.1    NWSH01001320    PCG71707.1    KJ995811    AIN39494.1    ODYU01007063    SOQ49501.1    ODYU01007325    SOQ50002.1    ODYU01007479    SOQ50286.1    ODYU01006337    SOQ48101.1    BABH01028746    BABH01028747    BABH01028748    BABH01034743    BABH01034744    BABH01034746    BABH01034747    RSAL01001640    RVE40744.1    ODYU01004596    SOQ44641.1    RSAL01000844    RVE41114.1    KQ459837    KPJ19761.1    BABH01013455    RSAL01000273    RVE43156.1    RVE41111.1    KQ459564    KPI99614.1    NWSH01006414    PCG63451.1    KZ149956    PZC76461.1    NWSH01001116    PCG72533.1    PZC76463.1    BABH01013458    BABH01013459    BABH01013460    RSAL01000231    RVE43837.1    NWSH01006200    PCG63597.1    PZC76464.1    PCG72532.1    RSAL01000083    RVE48485.1    AF098717    AAC97504.1    CH477371    EAT42428.1    CH916369    EDV93847.1    CH478998    EAT32533.1    KQ760645    OAD59676.1    JXUM01046680    KQ561486    KXJ78429.1    DS232811    EDS45917.1    DS231994    EDS30856.1    ADMH02000540    ETN66032.1    AXCN02001762    AAAB01008848    APCN01003535    EAA07042.4    CM000364    EDX12625.1    CH480827    EDW44795.1    CH964272    KRF99908.1    EDW83879.1    CH933806    EDW13691.2    JRES01000032    KNC34772.1    OUUW01000007    SPP83195.1    CH479179    EDW25175.1    AE014297    ACZ94929.1    X68131    AY541497    BK002598    AXCM01004244    AGB96034.1    CM000070    EDY68158.2    CH940652    EDW58924.2    KZ288187    PBC34719.1    CH902617    EDV42305.1    UFQT01001180    SSX29359.1    CM000160    EDW96959.1    NNAY01001189    OXU24803.1    GGMS01014387    MBY83590.1    GEBQ01006041    JAT33936.1    CP012526    ALC47695.1    KQ971317    EEZ99172.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    UP000005204    + More
UP000008820    UP000001070    UP000069272    UP000069940    UP000249989    UP000002320    UP000000673    UP000075886    UP000076407    UP000075902    UP000075840    UP000075882    UP000192221    UP000007062    UP000091820    UP000075885    UP000075900    UP000075881    UP000075884    UP000075903    UP000000304    UP000001292    UP000007798    UP000009192    UP000092443    UP000037069    UP000268350    UP000075920    UP000075880    UP000008744    UP000000803    UP000075883    UP000001819    UP000008792    UP000242457    UP000007801    UP000002282    UP000215335    UP000002358    UP000005203    UP000092553    UP000007266   

PRIDE

H9JQT0    H9JT77    H9JT78    H9ISL1    H9IT78    Q01603    + More

Pfam

PF03098   An_peroxidase        + More
PF00083   Sugar_tr
PF00075   RNase_H

Interpro

IPR010255   Haem_peroxidase_sf        + More
IPR029585   Pxd-like       
IPR019791   Haem_peroxidase_animal       
IPR037120   Haem_peroxidase_sf_animal       
IPR005828   MFS_sugar_transport-like       
IPR036259   MFS_trans_sf       
IPR020846   MFS_dom       
IPR036397   RNaseH_sf       
IPR002156   RNaseH_domain       
IPR012337   RNaseH-like_sf       

SUPFAM

SSF48113   SSF48113        + More
SSF103473   SSF103473       
SSF53098   SSF53098       

Gene 3D

1.10.640.10     3.30.420.10    

CDD

cd06174  MFS

ProteinModelPortal

A0A2A4IUC0   A0A2W1BYE5   A0A194Q9H2   A0A194RBC8   A0A194Q7Y0   A0A194RAP6   + More
I4DJ10   A0A194QDV6   A0A3S2NLC3   A0A2H1WGR9   A0A212ETD1   A0A2A4J7D3   A0A2W1BT67   A0A2H1W9U4   A0A2W1BT77   A0A2A4JI21   A0A088MGW5   A0A2H1W8U7   A0A2H1WAX3   A0A2H1WBG2   A0A2H1W4U4   H9JQT0   H9JT77   H9JT78   A0A437AS20   A0A2H1VUX0   A0A437ASV3   A0A0N0PED8   H9ISL1   A0A437AYB0   A0A3S2L850   A0A194Q3N0   A0A2A4IUP3   A0A2W1BQ93   A0A2A4JM77   A0A2W1BXH1   H9IT78   A0A3S2NMV9   A0A2A4IUD5   A0A2W1BS42   A0A2A4JMB0   A0A3S2M0V1   O96645   Q177U0   B4JHE0   Q16E76   A0A310SND6   A0A182FTE8   A0A182G7N2   B0XE84   B0WM28   W5JNS3   A0A182Q218   A0A182WXU8   A0A1S4H4U5   A0A182TM70   A0A182I5W9   A0A182KV49   A0A1W4VTT3   Q7QDZ3   A0A1A9W584   A0A182PRL2   A0A1Y9HDW6   A0A182KBY5   A0A1Y9H2I7   A0A182VL61   B4QWD4   B4IBN7   A0A0Q9WVU0   B4NJ86   B4KC82   A0A1A9Y5Z1   A0A0L0CRA6   A0A3B0JLT7   A0A1Y9IWB3   A0A182IZD9   B4G4K4   E1JIN0   Q01603   A0A182MPT8   A0A0B4KHM9   B5DWL8   B4M5J8   A0A2A3EU99   B3M2B4   A0A336MK45   B4PM93   A0A232F2X4   A0A2S2R1E6   A0A1B6MDD3   K7IYZ3   A0A088AE09   A0A0M4F792   D6WCM3  

PDB

6BMT     E-value=4.56872e-22,     Score=259

KEGG

101743638    K19511 peroxidase [EC:1.11.1.7] | (RefSeq) peroxidase-like

GO

GO:0042600   GO:0020037   GO:0004601   GO:0006979   GO:0016021   GO:0022857   GO:0046872   GO:0007306   GO:0005576   GO:0042744   GO:0051082   GO:0015074   GO:0030429   GO:0004003   GO:0005634   GO:0006289   GO:0016286   GO:0055114  

PANTHER

PTHR11475:SF86  

Subcellular location

Secreted  

Length:

505

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.12071

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00628

outside

1  -  505

 

 

Pi

215.824062

Theta

185.457818

Tajima's D

1.224901

CLR

0.006471

CSRT

0.72316384180791

Interpretation

Uncertain