Gene

KWMTBOMO12826

Annotation

PREDICTED:_sodium_channel_protein_Nach-like_[Bombyx_mori]

Location

Bomo_Chr22(+):803490-805498      View in EpiBrowser

Full name

Pickpocket protein 28      

Location in the cell

Mitochondrial   Reliability : 1.357 Nuclear   Reliability : 1.639

CDS

ATGGCTAGTGCAGTCGTGCAACTAAGCCGAGGCTTGAAATTGACACTGAATATTCCCAATATAAAAAGATACAACATCACTGATGATCGTATACACAAGTTTTTCAACGGACTAGCCGGCTTAAAAGATAATGTTAAGCAGAGTAACAAGTTCACAGAAATTCTGGCCATATTGAAACATCACTACTTTACAATGGACACGATAATGGAAGAAGTCCATCAGAAATGCGAAAACTTGTTAATCTATTGCTCGTTCAATAGAAAGGAGAAGCGATGTGACAATCTGTTCAGTCTCATCAAGACTTATGAGGGTTACTGCTGTACTTTCAATTACGCTGCTTTGAATGATGCAACACTCGAACAACTAAGGAGTGAAAATATTGGCACCGAAGAAAACTAA

Protein

MASAVVQLSRGLKLTLNIPNIKRYNITDDRIHKFFNGLAGLKDNVKQSNKFTEILAILKHHYFTMDTIMEEVHQKCENLLIYCSFNRKEKRCDNLFSLIKTYEGYCCTFNYAALNDATLEQLRSENIGTEEN

Description

Osmosensitive ion channel that mediates the cellular and behavioral response to water. Plays an essential role in gustatory water reception. Part of a complex that plays a role in tracheal liquid clearance. Probable role in sodium transport.

Similarity

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.

Keywords

Cell membrane   Complete proteome   Ion channel   Ion transport   Membrane   Reference proteome   Sodium   Sodium channel   Sodium transport   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Pickpocket protein 28

Uniprot

A0A2W1BTN9   A0A437B3J7   A0A310S8T3   A0A2J7PVC7   E2C5F8   A0A0L7RC93   + More
A0A154PGC8   A0A1B0CK88   A0A1B0D5E9   A0A088AUE3   K7INU5   A0A232F9M1   B4N1A0   B3N2P2   B3NW89   A0A067RK43   B3N0C8   A0A0P8Y7G7   B4R639   B4IEU0   A0A0L0CNA8   Q86LG1   A0A1B0CQE6   A0A2A3EN15   T1GV49   A0A336KF41   A0A158NHD4   A0A195EF39   B3MDJ9   A0A0P8XQJ1   A0A0P9AG67   A0A1W4VHZ0   A0A195B026   A0A2A3E3T2   A0A1J1J775   A0A1J1IMJ5   A0A151IQ85   A0A2A4K008   A0A195D4L0   A0A088AAB1   W5J8U6   A0A2A4JYA3   A0A195DZ79   A0A182UZ03  

Pubmed

28756777    20798317    20075255    28648823    17994087    24845553    + More
26108605    12571352    10731132    12537572    12848938    20445050    20364123    21347285    20920257    23761445   

EMBL

KZ149953    PZC76567.1    RSAL01000176    RVE45032.1    KQ763832    OAD54711.1    + More
NEVH01020964    PNF20288.1    GL452770    EFN76771.1    KQ414617    KOC68351.1    KQ434899    KZC10892.1    AJWK01015896    AJWK01015897    AJVK01011749    NNAY01000660    OXU27138.1    CH963920    EDW78093.1    CH905151    EDV29966.2    CH954180    EDV46428.1    KK852632    KDR19810.1    CH902640    EDV38332.1    KPU77367.1    CM000366    EDX18143.1    CH480832    EDW46194.1    JRES01000147    KNC33805.1    AY226552    AY226553    AE014298    BT122074    AAF48671.3    AAO47378.1    ADE06680.1    AJWK01023482    KZ288205    PBC33128.1    CAQQ02149202    CAQQ02149203    CAQQ02149204    UFQS01000390    UFQT01000390    SSX03496.1    SSX23861.1    ADTU01015614    KQ979039    KYN23422.1    CH902619    EDV37462.1    KPU76840.1    KPU76839.1    KQ976694    KYM77645.1    KZ288392    PBC26348.1    CVRI01000074    CRL08251.1    CVRI01000052    CRK99689.1    KQ976782    KYN08319.1    NWSH01000360    PCG77000.1    KQ976870    KYN07823.1    ADMH02001945    ETN60381.1    PCG77001.1    KQ980050    KYN18027.1   

Proteomes

UP000283053    UP000235965    UP000008237    UP000053825    UP000076502    UP000092461    + More
UP000092462    UP000005203    UP000002358    UP000215335    UP000007798    UP000007801    UP000008711    UP000027135    UP000000304    UP000001292    UP000037069    UP000000803    UP000242457    UP000015102    UP000005205    UP000078492    UP000192221    UP000078540    UP000183832    UP000078542    UP000218220    UP000000673    UP000075903   

PRIDE

Q86LG1   

Pfam

PF00858   ASC        + More
PF00400   WD40
PF12894   ANAPC4_WD40

Interpro

IPR001873   ENaC        + More
IPR020903   ENaC_CS       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR017986   WD40_repeat_dom       
IPR024977   Apc4_WD40_dom       
IPR001680   WD40_repeat       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       

SUPFAM

SSF50978   SSF50978       

Gene 3D

2.130.10.10    

ProteinModelPortal

A0A2W1BTN9   A0A437B3J7   A0A310S8T3   A0A2J7PVC7   E2C5F8   A0A0L7RC93   + More
A0A154PGC8   A0A1B0CK88   A0A1B0D5E9   A0A088AUE3   K7INU5   A0A232F9M1   B4N1A0   B3N2P2   B3NW89   A0A067RK43   B3N0C8   A0A0P8Y7G7   B4R639   B4IEU0   A0A0L0CNA8   Q86LG1   A0A1B0CQE6   A0A2A3EN15   T1GV49   A0A336KF41   A0A158NHD4   A0A195EF39   B3MDJ9   A0A0P8XQJ1   A0A0P9AG67   A0A1W4VHZ0   A0A195B026   A0A2A3E3T2   A0A1J1J775   A0A1J1IMJ5   A0A151IQ85   A0A2A4K008   A0A195D4L0   A0A088AAB1   W5J8U6   A0A2A4JYA3   A0A195DZ79   A0A182UZ03  

KEGG

101744791    K03440 acid-sensing ion channel, other | (RefSeq) sodium channel protein Nach-like

GO

GO:0005272   GO:0016021   GO:0060025   GO:0035002   GO:0071462   GO:0042756   GO:0005886   GO:0009415   GO:0006814   GO:0016020   GO:0006508   GO:0015074   GO:0030429   GO:0004003   GO:0005634   GO:0006289   GO:0016286  

PANTHER

PTHR11690  

Subcellular location

Cell membrane  

Length:

132

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.08355

Exp number, first 60 AAs:

0.00103

Total prob of N-in:

0.19785

outside

1  -  132

 

 

Pi

201.470672

Theta

197.99036

Tajima's D

0.046457

CLR

0

CSRT

0.379581020948953

Interpretation

Uncertain