Silkworm Genome Informatics Database

Gene

KWMTBOMO12771 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007203

Annotation

PREDICTED:_ras-specific_guanine_nucleotide-releasing_factor_1-like_[Bombyx_mori]

Location

Bomo_Chr21(+):14081964-14126873 View in EpiBrowser

Location in the cell

Nuclear Reliability : 3.94

CDS

ATGTTGAGTCCCAAGATTCAGCGCTCAGTTAGAGTCAATGACGGCCAGCTCCTTGCGCTATCTGATAGAGCGCAATTTGACCACTCACAGGCCGGGTACTTGCACAAGCGGAGTTCCGACAACACGAAATGGCAGTTAAGATGGTTCGTTCTGTATCAGAACATTCTGTTTTATTACGAATCGGAGAACAACACTCGTCCCACTGGCGTGCTCCTGCTGGAAGGATCATACTGCGAGAGACTTAGCAAATCGCCCATGGAACGCAATGCTTCGTTCTGTTTCACGATCTCGTACCGTCGTGAGAGTCAGAGGCAGTACGAGCTGCGGGCAGCTTCCGAAGTGGATTGCGTGCACTGGGTGGACGCCATCAGGGAGGCGAGTTTCAACAAGCTGCTCCTCCAAAAAGAGGAGTTGGAGCAGAAGCAGCTGCATCTTCTGCAGGTGGTCGAGAGCGAGCGCACTTCCCGATGGCAGTACGCGCAGCAGTGCGATGAACTGGCCAACGAGGTCAAAAAATTACGGGCTGAGCTGTGTTCGTATAAGAAAGAGCACGAGCCCTCGACGAGAGCTGCGTCTGAGTCCAGCTCATCGCCCGGTCATTCACCGGAGATAGATCCGGTGGAGCTCCGGAAGATAAAAAAAGTACAGAGTTTCTTCAGAGGCTGGTTGTGCAGAAGGCGCTGGAAGCAGATTGTGGACCAGTACATCAAGAGTCCACACGCCGAGAGCATGAGGAAACGAAACAGTCTTGTTTTCAAAATGGTTGAAGCCGAAGAAGAATATCTGGAACAATTGGAGATACTGGTAACATGTTTCCTTCGCCCGTTCAAAATGGCAGCCAGTTCGAAGAAGCCACCTTGCACGCACGAGGACGTAAACTCCATATTCCTGAACAGCGAGACGGTTCTGTTCCTCCACCAGATCTTCTTCAAGGGTTTGACTTCTAGAATGGAGTCCTGGCCCACGCTCGTGTTGGGAGACTTATTCGACATGCTCCTACCGATGCTGACCATCTACCAGGAGTACGTGAGGAACCATCATTATTCGCTACAAGTTCTGACGGAGTGCAAGCAGAGTCAGCCCTTTGCTCATCTGCTGACACGCCTCGAAAGCAAGCCCGCTTGTCAGGGACGATCGTTGGAGACTTTCCTCACTTATCCAATGCATCAGATACCGCGTTACATAATAACTCTGCACGAGCTATTGGCGCACACTCCGCACGACCACGTGGAGCGACGCAGCCTCCAGCACGCGCGGGCGCAGCTAGAAGAACTCTCCAGGCAGATGCACGACGAGGTGAGCGAGACAGAGAACCTTCGCAAAAACCTCGCCGTGGAGCGGATGATCATCGAGGGCTGCGACATTCTGCTGGACGTCAACCAAGTCTTCATTCGGCAAGGTACATTGTCGCAAGTGGTGGGTAAAGGCAGACGAGCGTCGCTCCAGGCTCGACAGGCGTTCCTCTTCAGCAACCACCTGCTGCTGACCACACGAGCAGCTGGGGGCAGGCTGCACCTGCCTGCTGCCGGGAGGCTGCCCCTGCACGACGCCTTGCTCATCGAAGACCCGTCAAACCACGACGACGACGATTCCACATCAGTGTGTTCGTCTCCCGGGGGGGACATGTACCAGGGGAAAGATTTTAAGATCCGCGTAGAAGTGAAGGGAGAACAGATCTGCGCGCACTTAGTGGCGGCGACGGTGGAGGAGAAGGCGGCGTGGACGAGCGAGCTGGCGCAGTGCATGGAGAGCGCGGCGCTGACGGCGCTGCTGCGCGCGTGCGGCGCGTGCGGCGGCGCCTCCGCCAGTCTGCCCGCCTGCCGCTCCGACCGAGCGCTCTTCACCGACGATGTCGACATCCGCTTCAGCAGGACGCTCAACTCCTGCAAGGTGCCGCAGATCCGGTCCGCCACGCCGCAGCGCCTGCTGCAGAGACTCACCGACCTGCGCTTCCTGTCCGTGGACTTCCTGAACACATTCCTGCTCACCTACCGCGTGTTCACGGACGGCGTGGCGGTGCTGGAGGCTCTCAAGCAGGTCTTCTACGAGCAGTCGCAGCAGGAGATGGAGCTGGCCCCACCGCCGGATGCCACTAGGAAGACCAGTGCCGCAAGCACCGTCTCTGGTTACGGGTCGGAGTACAGCGATCGCGATTGGCAGTCGCGTTTCTGGAGGGCTTCTAGAAAGAGCGAGGAAGAAGATAAGTTGTCTCCGTACCTGATGGCCCCGTCGCGAAGAACGTCCTCAGTCAGTAAGGGAGGCAAGGAGACCGAGGAGGACAACAGTCACTTGACCATACCCAAAATAATGGCGACGTCGTCTAGCAATGAAACGTTGAAAGGCACGTCGCCGTCATCTCCTGGCGCCCTCAGCTCCGTGACCCTGGTCGGGAGCCCCAAGAAGCCCGGCCCGGACGACGGCGCTAAGTCAGACCGCAAGTCTCCCACCAAGGACAACGACGCAGCTGCTGCCATCATGAAGGACGAAAGCATCGAGATGGTGGACCAGAGCGACGAGGACATCAAGTACAAGGAAGAAGAACAGGAGAAGAATAAATACAAGACGGATGATAAGTTTAAGCTGTCGCAGCGGTTCTCAGAGCGCGTTCGGACATCGTCGGAGAGTCCACGTCGCCTCCAGCCCTCGGCGGCCACCGCGGCGTCCGAGGCCAGGCGCTGCTCCGAGAGCGCGCGGGACTCCGGCGCCGCCGCCCCAGAGGAGCCCAGGAGAGCGTCCGATTCGGGAACTAGGTTTGGTGGTAGAAGGTCTGTTAGCGAGCGACGCTACACCAACTCGTCGATCAACAGCGAGCGACGCCGCTACTGGGGGGGCTCCGAGCCGCGCTCCTCCGTAACCTCACAGATATCACAAGTCACGCAGAACTACCGCCGCGAGACCAGCCAGCCCAAAGCAGGAGTGGTCATTACCTCGTTCCGCCAATCGCACCGGAGGAGCAGTACATCGACGGCGGCTGTCGCTTTTGCTGTCGCGACTTCCGCGTCGTCCAACCCGCGCTCCCCCCCGCCGACCTCCCCGCCGCCCGCGCGACGCGACTCCGTCATATCCACCGCCGCCACCATGAGGGTGCTCAACGTGCTGCGACACTGGATCTCTAAGCACTCGTACGACTTCTGGTCCAACGAGCGTCTCCGGGGCTTGACCATGGACTTCCTCAAGGAGATCGAGGGTAGCCCGGGCCTGCTGCCGGCGGAGCACAAGGCAGCGGCCCAGCTGCTTCGTCTGCTGGAGCGAGCGCCGGACCGGACCGTCGACCTGAAAGCGCTGTTTGCGGCACCCCCTGTTCCGACTAAAGAGAGCGTAGAAACACTATCAGCCCTGGAGATAGCAGAGCAGATGACCTATCTCGACTACCAAATATTCAGCTCTATCAACAGCGAGGAGTTCCTCGGCCAGGCGTGGACGAAGGCGGACAAGGCGGAACGCGCGCCGCACATCCTCATGATGACCTCCCACTTCAATCACATCTCGAATCTGGTTATTTCGGAAATACTCAGGAAATACACTCTGGCGGGTCGCGTGGCGGCCATCGAGAAGTGGGCGGCGGTGGCGGACATCGCGCGCTGCCTCCACAACTTCAACGGCGTCCTTCAGGTGTGCGCGGCGTTGTCCAACACCTCCGTGTACCGACTCAAGAAGACCTGGGACAAGGTGTCGAAAACGAGCCGCCACACGATCGAGCGCATGCAGACCATCATATCGTCAGAGTGCCGCTTCAGAATACTAAGAGACGCCTTGCACAGGTGCGACCCCCCCTGCATCCCCTACCTGGGCATGTACCTGTCCGACTTGTCATTCATCGACGAAGGCACGTCCAACTACACTCCCGACGGTCTACTCAACTTCTCCAAAATGAGAATGATTGCTCACGTTATCCGTGAAATAAGAAATTTCCAGCAAACTCCATACAAAATCGAACACATCCCAAAGGTGTGCGACTTCCTGCTTGAGCGGTCGCTGATCATCCCCGAGGAGCGGCAGTACACGCTGTCGCTGGAGCTGGAGCCGCGGGCGGCGCGCGGGTCGGGCGCGGGGCTGAGCTCCCCCGCGTCCTAG

Protein

MLSPKIQRSVRVNDGQLLALSDRAQFDHSQAGYLHKRSSDNTKWQLRWFVLYQNILFYYESENNTRPTGVLLLEGSYCERLSKSPMERNASFCFTISYRRESQRQYELRAASEVDCVHWVDAIREASFNKLLLQKEELEQKQLHLLQVVESERTSRWQYAQQCDELANEVKKLRAELCSYKKEHEPSTRAASESSSSPGHSPEIDPVELRKIKKVQSFFRGWLCRRRWKQIVDQYIKSPHAESMRKRNSLVFKMVEAEEEYLEQLEILVTCFLRPFKMAASSKKPPCTHEDVNSIFLNSETVLFLHQIFFKGLTSRMESWPTLVLGDLFDMLLPMLTIYQEYVRNHHYSLQVLTECKQSQPFAHLLTRLESKPACQGRSLETFLTYPMHQIPRYIITLHELLAHTPHDHVERRSLQHARAQLEELSRQMHDEVSETENLRKNLAVERMIIEGCDILLDVNQVFIRQGTLSQVVGKGRRASLQARQAFLFSNHLLLTTRAAGGRLHLPAAGRLPLHDALLIEDPSNHDDDDSTSVCSSPGGDMYQGKDFKIRVEVKGEQICAHLVAATVEEKAAWTSELAQCMESAALTALLRACGACGGASASLPACRSDRALFTDDVDIRFSRTLNSCKVPQIRSATPQRLLQRLTDLRFLSVDFLNTFLLTYRVFTDGVAVLEALKQVFYEQSQQEMELAPPPDATRKTSAASTVSGYGSEYSDRDWQSRFWRASRKSEEEDKLSPYLMAPSRRTSSVSKGGKETEEDNSHLTIPKIMATSSSNETLKGTSPSSPGALSSVTLVGSPKKPGPDDGAKSDRKSPTKDNDAAAAIMKDESIEMVDQSDEDIKYKEEEQEKNKYKTDDKFKLSQRFSERVRTSSESPRRLQPSAATAASEARRCSESARDSGAAAPEEPRRASDSGTRFGGRRSVSERRYTNSSINSERRRYWGGSEPRSSVTSQISQVTQNYRRETSQPKAGVVITSFRQSHRRSSTSTAAVAFAVATSASSNPRSPPPTSPPPARRDSVISTAATMRVLNVLRHWISKHSYDFWSNERLRGLTMDFLKEIEGSPGLLPAEHKAAAQLLRLLERAPDRTVDLKALFAAPPVPTKESVETLSALEIAEQMTYLDYQIFSSINSEEFLGQAWTKADKAERAPHILMMTSHFNHISNLVISEILRKYTLAGRVAAIEKWAAVADIARCLHNFNGVLQVCAALSNTSVYRLKKTWDKVSKTSRHTIERMQTIISSECRFRILRDALHRCDPPCIPYLGMYLSDLSFIDEGTSNYTPDGLLNFSKMRMIAHVIREIRNFQQTPYKIEHIPKVCDFLLERSLIIPEERQYTLSLELEPRAARGSGAGLSSPAS

Uniprot

A0A3S2L053 A0A0N1PHG8 A0A194QLZ0 A0A212FI89 A0A067QM88

Pubmed

26354079 22118469 24845553

EMBL

RSAL01000317 RVE42586.1 KQ460882 KPJ11473.1 KQ458981 KPJ04471.1 + More
AGBW02008415 OWR53454.1 KK853179 KDR10231.1

Proteomes

UP000283053 UP000053240 UP000053268 UP000007151 UP000027135

Pfam

PF00621   RhoGEF        + More
PF00169   PH
PF00618   RasGEF_N
PF00617   RasGEF

Interpro

IPR036964   RASGEF_cat_dom_sf        + More
IPR008937   Ras-like_GEF
IPR035899   DBL_dom_sf
IPR000219   DH-domain
IPR001849   PH_domain
IPR023578   Ras_GEF_dom_sf
IPR000048   IQ_motif_EF-hand-BS
IPR001895   RASGEF_cat_dom
IPR000651   Ras-like_Gua-exchang_fac_N
IPR011993   PH-like_dom_sf
IPR030745   RasGRF1
IPR019804   Ras_G-nucl-exch_fac_CS

SUPFAM

SSF48366 SSF48366 + More
SSF48065 SSF48065

Gene 3D

1.10.840.10 1.20.900.10 2.30.29.30

CDD

cd00160 RhoGEF
cd00155 RasGEF

ProteinModelPortal

A0A3S2L053 A0A0N1PHG8 A0A194QLZ0 A0A212FI89 A0A067QM88

PDB

2IJE E-value=6.45835e-80, Score=762

KEGG

101743588 K04349 Ras-specific guanine nucleotide-releasing factor 1 | (RefSeq) ras-specific guanine nucleotide

GO

GO:0005085 GO:0005089 GO:0035023 GO:0007264 GO:0005515 GO:0048015 GO:0004003 GO:0005634 GO:0006289 GO:0016286

PANTHER

PTHR23113 PTHR23113:SF193

Length:

1357

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01114

Exp number, first 60 AAs:

0.00289

Total prob of N-in:

0.00034

outside

1 - 1357

Pi

21.889899

Theta

19.949216

Tajima's D

-1.238456

CLR

0.712062

CSRT

0.0975951202439878

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics