Gene

KWMTBOMO12768

Pre Gene Modal

BGIBMGA007201

Annotation

PREDICTED:_katanin_p60_ATPase-containing_subunit_A-like_2_[Amyelois_transitella]

Location

Bomo_Chr21(+):14063544-14066001      View in EpiBrowser

Full name

Katanin p60 ATPase-containing subunit A-like 2      

Alternative Name

p60 katanin-like 2

Location in the cell

Cytoplasmic   Reliability : 1.601

CDS

ATGGTGGATTTTTCAGAGATACAGAACACATCTACAGCTCTTGACAGGAAATCGTTAGCCGGCTTCTTGACCAGCGCTGCTCCTGAAAAGAAGCAGTTGGCGGAGCTTCTGTACCAAAATATTATCAGGAGTTCAGGAGTAACGTGGGACGATATTAGAGGCTTGAATTCGGCCAAGAGTTTGTTGATGGAGTCCGTCATATATCCTGTTAGGTACCCGGATGTGTTTACCGGGCTTCTCGAGCCCTGGCGAGGGGTGCTGCTTCACGGTCCTCCAGGCACAGGCAAGACACTGCTCGCGAAAGCAGTGGCCAGTGAAAGCTGCTGCACTTTCTTTAATATATCTTGCAGCACGATCGTTAACAAATGGAGAGGCGAGTCTGAGAAGATTGTAAAGGTTTTATTCGAAATGGCATCGTACTACTCGCCGTCGATAATCTTCATAGACGAAGTGGAGACTCTGGCCTCGGATCGATCTGCTGCTGGCGAACACGAGGCTTCCCGGAGATTGAAGTCCCAACTTCTAACGGAACTGGACGGCATAAATGAGAGAGAAGGCATTGTATTTTTACTGGCCAATTCTAATATGCCTTGGGATTTGGACCCGGCTATGTTGAGACGTCTAGAAAAAAGGATTCACATTCCGCTGCCGGACGCAAAAACGCGCGAAGAGCTCTTCCGGAAGTTTCTGAATAGCAGAAACATCGAGCTGTATCCTAAGATGGATTATAAGGAGTTAGCTTCGAAGACCGAAGGCTATTCGGGCAGCGACATCAAGCTGGTGTGTAAGGAGGCGCTGATGTCCACCGTGAGGAAATTGTTACCGAATTTACCGGGAAACAGTACGTGTGAGATTTTTATTGTTATGTCACTAGAGAAATGTCATAATTACATTTAA

Protein

MVDFSEIQNTSTALDRKSLAGFLTSAAPEKKQLAELLYQNIIRSSGVTWDDIRGLNSAKSLLMESVIYPVRYPDVFTGLLEPWRGVLLHGPPGTGKTLLAKAVASESCCTFFNISCSTIVNKWRGESEKIVKVLFEMASYYSPSIIFIDEVETLASDRSAAGEHEASRRLKSQLLTELDGINEREGIVFLLANSNMPWDLDPAMLRRLEKRIHIPLPDAKTREELFRKFLNSRNIELYPKMDYKELASKTEGYSGSDIKLVCKEALMSTVRKLLPNLPGNSTCEIFIVMSLEKCHNYI

Description

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.

Catalytic Activity

n ATP + n H(2)O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.

Similarity

Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
Belongs to the AAA ATPase family.

Keywords

ATP-binding   Complete proteome   Cytoplasm   Cytoskeleton   Isomerase   Microtubule   Nucleotide-binding   Reference proteome  

Feature

chain  Katanin p60 ATPase-containing subunit A-like 2

Uniprot

H9JCF6   A0A2A4JZ04   A0A2W1BJJ4   A0A2H1VSS4   A0A3S2NRB3   A0A194QGC4   + More
A0A0N1I658   A0A0L7LMX4   A0A093CM88   A0A091HSD3   A0A093H1L3   A0A091XSW2   A0A093NWI0   A0A093F191   A0A091FMX8   A0A1D5PYL3   A0A452IR85   A0A087R0C7   A0A091R3G7   A0A287LA55   A0A3Q1DGH0   A0A151MWE3   A0A151MWD8   A0A151MWJ9   A0A1U7SYC0   A0A1U7SNC2   A0A3Q0FVD5   A0A151MWJ4   A0A446NMV2   A0A1U7SJF4   A0A1U7SVS7   A0A0A9X5I1   A0A091PIV4   A0A287LA64   A0A1S3H1Z5   A0A3B5A0K8   M7BWC8   A0A453FJE9   A0A287LA62   A0A287LA49   A0A287LA51   A0A2I0M0J5   A0A453FJA8   A0A0E0JNW0   A0A1B6LXB5   A0A287LM58   A0A0Q3Q527   A0A453FJB3   A0A287LM65   A0A346BPW1   A0A287LA42   A0A287LM72   A0A2S3HRK8   A0A2T7DGM5   A0A093FJU1   A0A287LA47   A0A453FE27   A0A453FJC5   A0A287LA66   A0A077RV52   A0A287LM59   A0A453FJF8   A0A3B6FTL6   A0A446PZR2   A0A287LA73   A0A3B6EJQ5   A0A446NPQ9   A2DGJ5   A0A1L8I2W9   A0A453FJF4   A0A453FJ91   A0A287LM47   I1NRR8   W5CPE3   A0A3P9INE9   A0A346BPW0   A0JMA9   A0A453FE23   A0A3B4XPP7   A0A287LM51   A0A3P8RXY2   Q7XXR9   A0A446NML9   A0A453FE39   F6SG18   F7D733   A0A453FJF9   A0A453FJA1   A0A093GMT0   A0A0P6JA20   A0A3Q1GZL5   A0A453FJC0   H2M8T2   B9EZQ8   A0A1B6HFD7   A0A1D6NB67   A0A3B6EM09   A0A446NMM0   A0A0D3EU60   A0A3P9KIQ6  

EC Number

5.6.1.1

Pubmed

19121390    28756777    26354079    26227816    15592404    28562605    + More
23075845    22293439    25401762    23624526    25035499    29158546    23371554    25035497    17218520    27762356    17554307    12447438    16100779    15659629    16381971    23299411    24280374    20431018    15685292   

EMBL

BABH01031599    BABH01031600    NWSH01000408    PCG76612.1    KZ150013    PZC75038.1    + More
ODYU01004213    SOQ43848.1    RSAL01000317    RVE42588.1    KQ458981    KPJ04469.1    KQ460882    KPJ11471.1    JTDY01000530    KOB76780.1    KL243741    KFV13432.1    KL217725    KFO98032.1    KL205903    KFV76438.1    KK735820    KFR16046.1    KL224987    KFW66340.1    KL475525    KFV20461.1    KL447179    KFO70514.1    AC197816    KL226008    KFM06931.1    KK689707    KFQ16084.1    AKHW03004724    KYO28871.1    KYO28873.1    KYO28872.1    KYO28874.1    LT934115    VAH63380.1    GBHO01028375    JAG15229.1    KL390499    KFP91450.1    KB514475    EMP40130.1    AKCR02000053    PKK23202.1    GEBQ01011660    JAT28317.1    LMAW01001525    KQK83300.1    MH036374    AXL66108.1    CM008050    PAN28450.1    CM009753    PUZ54718.1    KK633237    KFV56900.1    HG670306    CDM81692.1    CDM84230.1    LT934116    VAH79831.1    VAH64062.1    DS113198    EAY20382.1    CM004466    OCU02704.1    CBUC010000081    CDJ26359.1    CDM82078.1    MH036373    AXL66107.1    BC125808    AB110177    AP003375    AP008207    AP014957    BAC78569.1    BAD87507.1    BAF06207.1    BAS74414.1    VAH63378.1    AAMC01058987    AAMC01058988    AAMC01058989    AAMC01058990    AAMC01058991    AAMC01058992    AAMC01058993    AAMC01058994    AAMC01058995    KL216209    KFV68282.1    GEBF01006421    JAN97211.1    CM000138    EEE55402.1    GECU01034318    JAS73388.1    CM007649    ONM37782.1    VAH63377.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000053240    UP000037510    + More
UP000054308    UP000053584    UP000053605    UP000054081    UP000053760    UP000000539    UP000291020    UP000053286    UP000011116    UP000257160    UP000050525    UP000189705    UP000085678    UP000261400    UP000031443    UP000015105    UP000053872    UP000026962    UP000051836    UP000243499    UP000244336    UP000019116    UP000001542    UP000186698    UP000007306    UP000265200    UP000008143    UP000261360    UP000265080    UP000059680    UP000053875    UP000265040    UP000001038    UP000007305    UP000026960    UP000265180   

PRIDE

H9JCF6    W5CPE3    A0JMA9   

Pfam

PF17862   AAA_lid_3        + More
PF00004   AAA
PF08513   LisH

Interpro

IPR006594   LisH        + More
IPR003593   AAA+_ATPase       
IPR041569   AAA_lid_3       
IPR003959   ATPase_AAA_core       
IPR027417   P-loop_NTPase       
IPR027497   Katanin_p60_AL2       
IPR003960   ATPase_AAA_CS       

SUPFAM

SSF52540   SSF52540       

ProteinModelPortal

H9JCF6   A0A2A4JZ04   A0A2W1BJJ4   A0A2H1VSS4   A0A3S2NRB3   A0A194QGC4   + More
A0A0N1I658   A0A0L7LMX4   A0A093CM88   A0A091HSD3   A0A093H1L3   A0A091XSW2   A0A093NWI0   A0A093F191   A0A091FMX8   A0A1D5PYL3   A0A452IR85   A0A087R0C7   A0A091R3G7   A0A287LA55   A0A3Q1DGH0   A0A151MWE3   A0A151MWD8   A0A151MWJ9   A0A1U7SYC0   A0A1U7SNC2   A0A3Q0FVD5   A0A151MWJ4   A0A446NMV2   A0A1U7SJF4   A0A1U7SVS7   A0A0A9X5I1   A0A091PIV4   A0A287LA64   A0A1S3H1Z5   A0A3B5A0K8   M7BWC8   A0A453FJE9   A0A287LA62   A0A287LA49   A0A287LA51   A0A2I0M0J5   A0A453FJA8   A0A0E0JNW0   A0A1B6LXB5   A0A287LM58   A0A0Q3Q527   A0A453FJB3   A0A287LM65   A0A346BPW1   A0A287LA42   A0A287LM72   A0A2S3HRK8   A0A2T7DGM5   A0A093FJU1   A0A287LA47   A0A453FE27   A0A453FJC5   A0A287LA66   A0A077RV52   A0A287LM59   A0A453FJF8   A0A3B6FTL6   A0A446PZR2   A0A287LA73   A0A3B6EJQ5   A0A446NPQ9   A2DGJ5   A0A1L8I2W9   A0A453FJF4   A0A453FJ91   A0A287LM47   I1NRR8   W5CPE3   A0A3P9INE9   A0A346BPW0   A0JMA9   A0A453FE23   A0A3B4XPP7   A0A287LM51   A0A3P8RXY2   Q7XXR9   A0A446NML9   A0A453FE39   F6SG18   F7D733   A0A453FJF9   A0A453FJA1   A0A093GMT0   A0A0P6JA20   A0A3Q1GZL5   A0A453FJC0   H2M8T2   B9EZQ8   A0A1B6HFD7   A0A1D6NB67   A0A3B6EM09   A0A446NMM0   A0A0D3EU60   A0A3P9KIQ6  

PDB

6B5C     E-value=6.64093e-69,     Score=661

KEGG

101739866    K07767 katanin p60 ATPase-containing subunit A1 [EC:5.6.1.1] | (RefSeq) katanin p60 ATPase-containin

GO

GO:0005524   GO:0000922   GO:0016853   GO:0005737   GO:0051013   GO:0008017   GO:0005874   GO:0005634   GO:0016887   GO:0031122   GO:0008568   GO:0005819   GO:0016787   GO:0005488   GO:0016301   GO:0016303   GO:0046854   GO:0048015   GO:0004003   GO:0006289   GO:0016286  

Subcellular location

Cytoplasm   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.
Cytoskeleton   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.
Spindle   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.
Spindle pole   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.

Length:

298

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00781000000000001

Exp number, first 60 AAs:

8e-05

Total prob of N-in:

0.03153

outside

1  -  298

 

 

Pi

30.368611

Theta

26.317493

Tajima's D

0.309275

CLR

0

CSRT

0.465876706164692

Interpretation

Uncertain