Silkworm Genome Informatics Database

Gene

KWMTBOMO12767

Pre Gene Modal

BGIBMGA007201

Annotation

PREDICTED:_katanin_p60_ATPase-containing_subunit_A-like_2_[Amyelois_transitella]

Location

Bomo_Chr21(+):14061104-14062838 View in EpiBrowser

Full name

Katanin p60 ATPase-containing subunit A-like 2

Alternative Name

p60 katanin-like 2

Location in the cell

Nuclear Reliability : 2.975

CDS

ATGACGACTAATAATAGACCCATGAGCAAAATGAGAATGATCGAGTCGAAAGAAGCCTTATTCAGAGCAAGGAAACGTATACTCAAGTACATGGTTCTTGGTTATTTGAAGCAGGAGGGATATCTGCTAACAGCAGAGACTTTTAACACAGAAGCGAATCTTACAGGAGAGTATGAAGTCTGCGACAATATTGACTTGGATATTATACTCCAGGATTATTGCAGCTATTATCTTATACGATTTAACAAGCAGCCCCAGTTCTGTCGTAAAGTGGAGGAGAAACCAGTACGTCCGCAGACCAGGAGGGTGAAGCCAGAACGAAGCCAAGTTCTCGATGTGGTCGAGAAAAATGATCTGGATTTACCTTCTACTTTCACTGTAACGAGTTTACTGAAGGTAAAATCGTCTTTTAATATGAATTTCAGGATGATGATAGCTTTAGATATCTGA

Protein

MTTNNRPMSKMRMIESKEALFRARKRILKYMVLGYLKQEGYLLTAETFNTEANLTGEYEVCDNIDLDIILQDYCSYYLIRFNKQPQFCRKVEEKPVRPQTRRVKPERSQVLDVVEKNDLDLPSTFTVTSLLKVKSSFNMNFRMMIALDI

Description

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.

Catalytic Activity

n ATP + n H(2)O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.

Similarity

Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
Belongs to the AAA ATPase family.

Uniprot

H9JCF6 A0A2A4JZ04 A0A2W1BJJ4 A0A212EQX1 A0A2H1VSS4 A0A3S2NRB3 + More
A0A0N1I658 A0A0L7LMX4 A0A194QGC4 A0A2J7RJS6 A0A182QCL9 A0A067QGJ5 A0A2C9JJS6 U4UBM6 A0A182YID3 A0A2C9JJS9 A0A1D5PYL3 G1MZ41 I3LEM5 A0A2Y9TAY9 A0A226P001 A0A1I8GHE0 A0A2K6ETX6 A0A2Y9TGW6 A0A2R7WS77

EC Number

5.6.1.1

Pubmed

19121390 28756777 22118469 26354079 26227816 24845553 + More
15562597 23537049 25244985 15592404 20838655 30723633 24621616 26392545

EMBL

BABH01031599 BABH01031600 NWSH01000408 PCG76612.1 KZ150013 PZC75038.1 + More
AGBW02013204 OWR43875.1 ODYU01004213 SOQ43848.1 RSAL01000317 RVE42588.1 KQ460882 KPJ11471.1 JTDY01000530 KOB76780.1 KQ458981 KPJ04469.1 NEVH01002988 PNF41094.1 AXCN02000285 KK853510 KDR07071.1 KB632281 ERL91324.1 AC197816 AEMK02000004 DQIR01030668 HCZ86143.1 AWGT02000242 OXB72932.1 KK855318 PTY21980.1

Proteomes

UP000005204 UP000218220 UP000007151 UP000283053 UP000053240 UP000037510 + More
UP000053268 UP000235965 UP000075886 UP000027135 UP000076420 UP000030742 UP000076408 UP000000539 UP000001645 UP000008227 UP000248484 UP000198419 UP000095280 UP000233160

PRIDE

H9JCF6 I3LEM5

Pfam

PF17862   AAA_lid_3        + More
PF00004   AAA
PF08513   LisH

Interpro

IPR006594   LisH        + More
IPR003593   AAA+_ATPase
IPR041569   AAA_lid_3
IPR003959   ATPase_AAA_core
IPR027417   P-loop_NTPase
IPR027497   Katanin_p60_AL2
IPR003960   ATPase_AAA_CS

SUPFAM

SSF52540 SSF52540

ProteinModelPortal

H9JCF6 A0A2A4JZ04 A0A2W1BJJ4 A0A212EQX1 A0A2H1VSS4 A0A3S2NRB3 + More
A0A0N1I658 A0A0L7LMX4 A0A194QGC4 A0A2J7RJS6 A0A182QCL9 A0A067QGJ5 A0A2C9JJS6 U4UBM6 A0A182YID3 A0A2C9JJS9 A0A1D5PYL3 G1MZ41 I3LEM5 A0A2Y9TAY9 A0A226P001 A0A1I8GHE0 A0A2K6ETX6 A0A2Y9TGW6 A0A2R7WS77

KEGG

101739866 K07767 katanin p60 ATPase-containing subunit A1 [EC:5.6.1.1] | (RefSeq) katanin p60 ATPase-containin

GO

GO:0005524 GO:0000922 GO:0016853 GO:0005737 GO:0051013 GO:0008017 GO:0005874 GO:0005634 GO:0016887 GO:0031122 GO:0008568 GO:0005515 GO:0005488 GO:0016301 GO:0016303 GO:0046854 GO:0048015 GO:0004003 GO:0006289 GO:0016286

Subcellular location

Cytoplasm   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.
Cytoskeleton   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.
Spindle   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.
Spindle pole   Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.   With evidence from 1 publications.

Length:

149

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0194

Exp number, first 60 AAs:

0.016

Total prob of N-in:

0.53932

inside

1 - 149

Pi

30.737699

Theta

30.591506

Tajima's D

-0.219744

CLR

0.994516

CSRT

0.312734363281836

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics