Gene

KWMTBOMO12755

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr21(-):13901799-13903663      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 1.77

CDS

ATGGTCAGGAACGACAGACTCTCTGCTCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGCATGGGAAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGACTTGACGCGTTAGTTGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGAGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGACTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTACCCCGTCTCGTCAGGATACCGCTGAAGCCATAGACATCTTAACGGAACTCCTTAGAGCTAAGAACGCCTCAATACGCGCCTACGACAGGTATCCTACCGCGGGAAATCGTATTCGAATGCGTGCCCTACAACGCAACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGACAAAGCAGAGTTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGTCTCCTTGCCACCCTCGGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATGTCTAACCGCGATATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAA

Protein

MVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLSLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSTPSRQDTAEAIDILTELLRAKNASIRAYDRYPTAGNRIRMRALQRNVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDDKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRVSLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGMSNRDIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGAPPHGAHSCGA

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   D7EM17   K7IN67   A0A139WA11   X1WQI9   A0A087THU2   A0A023EYS8   A0A1B6MIM7   A0A2S2QEE0   A0A2S2NJB5   A0A087U3K8   V5GNJ2   X1WNI2   A0A087T3W0   A0A2S2PPK8   X1X0M4   T1ID59   A0A1Y1K0C8   J9LC21   A0A2S2PEZ9   A0A2S2PJ52   A0A224X6Q4   J9MAC6   A0A2S2NCK2   V5GNF3   A0A224XB44   A0A2A4IUM2   X1WZH0   A0A2J7R7D0   A0A087UCW3   A0A224X6T4   A0A2S2PA10   X1WLB2   J9KKL6   X1WKS2   A0A2S2N6Q7   A0A2H8TF37   X1WXR6   J9MAR0   X1WVL6   J9JZG6   J9M522   A0A224XI99   A0A087UB64   A0A2J7QR37   A0A2J7RE85   A0A2J7QY69   A0A2J7PBY3   A0A2M4AQK3   A0A2M4AQV0   A0A2J7RB85   A0A2J7PP17   J9JS95   A0A1Y1LKN6   X1WK15   J9LFC9   X1WIX8   J9LK81   J9KPF1   A0A224X6U5   A0A069DZL8   A0A2S2P6H1   J9KLB1   A0A2J7PU96   A0A2S2QDN9   A0A1Y1MT28   A0A1Y1KFT3   A0A224X6S1   A0A2S2R7N0   A0A1Y1KFR3   A0A232ENU1   A0A2G3AQH2   N6UXC7   A0A3S2NJ07   J9M1C3   A0A2J7QB68   A0A146KV64   A0A2S2NPT6   P21328   A0A087UGF5   A0A2S2NPG3   A0A2J7RQ60   A0A2S2PJG2   J9LVT4   A0A2S2Q2R8   A0A224XJI0   A0A2S2P7B2   A0A224X746   A0A2J7RMG0   A0A224XF24   A0A0J7K3N0   Q24335   P21329  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
20075255    25474469    26334808    28648823    29089032    23537049    26823975    2463954    3040362    1714378    2441397    1701254   

EMBL

U07847    AAA17752.1    AB055391    BAB21761.1    AB018558    BAA76304.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ973412    EFA12510.2    KQ971729    KYB24751.1    ABLF02022418    KK115285    KFM64681.1    GBBI01004395    JAC14317.1    GEBQ01004157    JAT35820.1    GGMS01006359    MBY75562.1    GGMR01004661    MBY17280.1    KK118005    KFM71947.1    GALX01005299    JAB63167.1    ABLF02008153    ABLF02008462    ABLF02008464    KK113281    KFM59799.1    GGMR01018716    MBY31335.1    ABLF02065839    ACPB03027378    GEZM01099921    GEZM01099920    GEZM01099918    GEZM01099906    JAV53125.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGMR01015412    MBY28031.1    GGMR01016297    MBY28916.1    GFTR01008279    JAW08147.1    ABLF02007779    ABLF02007782    ABLF02050375    GGMR01002322    MBY14941.1    GALX01005359    JAB63107.1    GFTR01008262    JAW08164.1    NWSH01007753    PCG62823.1    ABLF02034467    NEVH01006736    PNF36716.1    KK119261    KFM75202.1    GFTR01008261    JAW08165.1    GGMR01013409    MBY26028.1    ABLF02042518    ABLF02057746    ABLF02015631    ABLF02021986    ABLF02021987    ABLF02021991    ABLF02005245    ABLF02013477    ABLF02047385    ABLF02066435    GGMR01000226    MBY12845.1    GFXV01000908    MBW12713.1    ABLF02008605    ABLF02008608    ABLF02008609    ABLF02008610    ABLF02017023    ABLF02037715    ABLF02042385    ABLF02037436    ABLF02024246    GFTR01008256    JAW08170.1    KK119069    KFM74603.1    NEVH01011985    PNF31054.1    NEVH01005277    PNF39135.1    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    GGFK01009732    MBW43053.1    GGFK01009846    MBW43167.1    NEVH01005923    PNF38085.1    NEVH01023280    PNF18085.1    ABLF02028535    ABLF02028545    GEZM01053022    JAV74219.1    ABLF02012584    ABLF02013765    ABLF02024884    ABLF02023911    ABLF02017874    ABLF02027031    ABLF02023551    ABLF02023561    ABLF02041767    GFTR01008251    JAW08175.1    GBGD01000415    JAC88474.1    GGMR01012189    MBY24808.1    ABLF02040174    ABLF02040183    ABLF02055266    NEVH01021205    PNF19912.1    GGMS01006655    MBY75858.1    GEZM01021881    JAV88842.1    GEZM01084970    JAV60359.1    GFTR01008271    JAW08155.1    GGMS01016818    MBY86021.1    GEZM01084969    JAV60363.1    NNAY01003095    OXU19992.1    MCIT02004487    PHT96476.1    APGK01002019    KB734578    ENN83542.1    RSAL01000708    RVE41206.1    ABLF02006577    ABLF02015943    ABLF02049076    ABLF02052356    NEVH01016302    PNF25823.1    GDHC01018248    JAQ00381.1    GGMR01006581    MBY19200.1    M22874    M38643    KK119692    KFM76444.1    GGMR01006408    MBY19027.1    NEVH01001347    PNF42966.1    GGMR01016905    MBY29524.1    ABLF02003241    ABLF02003242    ABLF02025904    GGMS01002786    MBY71989.1    GFTR01008257    JAW08169.1    GGMR01012676    MBY25295.1    GFTR01008151    JAW08275.1    NEVH01002556    PNF42024.1    GFTR01008038    JAW08388.1    LBMM01015125    KMQ84919.1    M17214    AAA28508.1    M38437   

Proteomes

UP000053268    UP000007266    UP000002358    UP000007819    UP000054359    UP000015103    + More
UP000218220    UP000235965    UP000215335    UP000224522    UP000019118    UP000283053    UP000036403   

PRIDE

Q93137    Q9BPQ0    Q9XXW0    P21328    Q24335    P21329    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2
PF03564   DUF1759
PF18701   DUF5641
PF00665   rve
PF05380   Peptidase_A17
PF17921   Integrase_H2C2
PF05585   DUF1758
PF14291   DUF4371

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       
IPR041588   Integrase_H2C2       
IPR036397   RNaseH_sf       
IPR005312   DUF1759       
IPR040676   DUF5641       
IPR008737   Peptidase_asp_put       
IPR008042   Retrotrans_Pao       
IPR012337   RNaseH-like_sf       
IPR001584   Integrase_cat-core       
IPR025398   DUF4371       

SUPFAM

SSF56219   SSF56219        + More
SSF53098   SSF53098       

Gene 3D

3.60.10.10     3.30.420.10    

ProteinModelPortal

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   D7EM17   K7IN67   A0A139WA11   X1WQI9   A0A087THU2   A0A023EYS8   A0A1B6MIM7   A0A2S2QEE0   A0A2S2NJB5   A0A087U3K8   V5GNJ2   X1WNI2   A0A087T3W0   A0A2S2PPK8   X1X0M4   T1ID59   A0A1Y1K0C8   J9LC21   A0A2S2PEZ9   A0A2S2PJ52   A0A224X6Q4   J9MAC6   A0A2S2NCK2   V5GNF3   A0A224XB44   A0A2A4IUM2   X1WZH0   A0A2J7R7D0   A0A087UCW3   A0A224X6T4   A0A2S2PA10   X1WLB2   J9KKL6   X1WKS2   A0A2S2N6Q7   A0A2H8TF37   X1WXR6   J9MAR0   X1WVL6   J9JZG6   J9M522   A0A224XI99   A0A087UB64   A0A2J7QR37   A0A2J7RE85   A0A2J7QY69   A0A2J7PBY3   A0A2M4AQK3   A0A2M4AQV0   A0A2J7RB85   A0A2J7PP17   J9JS95   A0A1Y1LKN6   X1WK15   J9LFC9   X1WIX8   J9LK81   J9KPF1   A0A224X6U5   A0A069DZL8   A0A2S2P6H1   J9KLB1   A0A2J7PU96   A0A2S2QDN9   A0A1Y1MT28   A0A1Y1KFT3   A0A224X6S1   A0A2S2R7N0   A0A1Y1KFR3   A0A232ENU1   A0A2G3AQH2   N6UXC7   A0A3S2NJ07   J9M1C3   A0A2J7QB68   A0A146KV64   A0A2S2NPT6   P21328   A0A087UGF5   A0A2S2NPG3   A0A2J7RQ60   A0A2S2PJG2   J9LVT4   A0A2S2Q2R8   A0A224XJI0   A0A2S2P7B2   A0A224X746   A0A2J7RMG0   A0A224XF24   A0A0J7K3N0   Q24335   P21329  

KEGG

105842617    no KO assigned | (RefSeq) uncharacterized LOC105842617

GO

GO:0003964   GO:0004519   GO:0016021   GO:0003676   GO:0015074  

Length:

434

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

14.30697

Exp number, first 60 AAs:

0.05318

Total prob of N-in:

0.11027

outside

1  -  434

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

25.211895

CSRT

0

Interpretation

Uncertain