Gene

KWMTBOMO12736  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007173

Annotation

putative_Syntaxin-18_[Danaus_plexippus]

Location

Bomo_Chr21(-):13552485-13554189      View in EpiBrowser

Full name

GPI inositol-deacylase       + More
Syntaxin-18      

Location in the cell

Nuclear   Reliability : 3.022

CDS

ATGGATATAACACCATTATTTAAGGCTTGCATAAAAACTGTTAAAACTCGTAACAAGGCTTTCGGCATACACAGTCCGATTAGCGAAGATAAGCAACGCATATTGAGGGTGAAATCAAAAAATGCTTTCATGGCAACAGCTAAGGATATTTGTTCACAAATTACAAAGCTTAGGGACTTTTTATTGGAACACCGCGATAAATATTTAAGCTTCTTCAATAATGTTACTGGAGACGATATGTCTGATGAAGAGCGCGACCAAATAGACACCGGTGCGCAACGTATCATGAACACATGCTCACACCTGCTAAAAGAGTTCAGGAATGATAATCGAAGAACTACAGTGACCCCACAAACTAGGGAATATATGGACTCAGTCGTAGATTTAATTGATGCTTATTTAAAAGCTGTTTGTAAAGTGCATAGTGAATTGAAAGCAATGAGAGTTAAGCGAGCTTTAGATATGAGAAAATTGTCTAGACTTGAGCTACCAGCGACCAAATCTAGTATTCCTAATCCGTTTACACTAGATAAGGTAATAGAAAAAGAGAATGAGACAGAAGATGAAAAAGAAAATACAAAAACAAAATTAGACTTATCAGAGAATGAGATGGCAATTATGTCTGATGAAGGAGAGTTGACTTCAGAAGAGTTGCAAATGTTTGAGTCGGAGAATGTACAGCTGTTAAATGAACTAAACAGTATGACGGAAGAAGTTAAACAAATTGAAAGCAAAGTACTACACATTGCAGAACTTCAAGAAATATTTACTGAAAAGGTTTTACAACAAGAACAAGACATAGATAGAATATCGAATACAGTTGTCGGGGCAACTGAAAACGTTAAGGATGCCAATGAACAGATTAAGCAAGCTATACAAAGAAACGCAGGCCTAAGAGTATATGTTCTGTTCTTCTTACTGGTCATGTCGTTCAGTTTGCTGTTCCTAGATTGGTATAATGATTAA

Protein

MDITPLFKACIKTVKTRNKAFGIHSPISEDKQRILRVKSKNAFMATAKDICSQITKLRDFLLEHRDKYLSFFNNVTGDDMSDEERDQIDTGAQRIMNTCSHLLKEFRNDNRRTTVTPQTREYMDSVVDLIDAYLKAVCKVHSELKAMRVKRALDMRKLSRLELPATKSSIPNPFTLDKVIEKENETEDEKENTKTKLDLSENEMAIMSDEGELTSEELQMFESENVQLLNELNSMTEEVKQIESKVLHIAELQEIFTEKVLQQEQDIDRISNTVVGATENVKDANEQIKQAIQRNAGLRVYVLFFLLVMSFSLLFLDWYND

Description

Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

Similarity

Belongs to the GPI inositol-deacylase family.
Belongs to the syntaxin family.

Keywords

Coiled coil   Complete proteome   Endoplasmic reticulum   ER-Golgi transport   Membrane   Protein transport   Reference proteome   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Syntaxin-18

Uniprot

H9JCC8   S4NY43   A0A1E1VYH1   A0A0N1IER1   A0A194QG14   A0A2W1BK28   + More
A0A2A4JX64   A0A3S2P5X2   A0A2H1VLK1   A0A212FCM4   A0A0L7KTD5   A0A2P8YJH0   A0A2J7R1B9   A0A067RBV0   A0A1B6CVB8   A0A1B6IXZ2   A0A1B6LMT0   A0A0M9A980   A0A158NM72   A0A195BWY4   A0A151JLI5   A0A151X1X5   F4WK14   A0A151IE89   A0A151JTN8   A0A2A3ENI4   A0A1B6GGX0   A0A088A105   A0A0L7QUJ3   E9J4J2   A0A154PSE5   A0A0J7KWA0   A0A2D0QAZ0   E2C2S7   A0A3B4C8D5   E3TD31   E2ABW1   A0A3P8S1C0   A0A3Q4HLZ3   A0A3P8PF05   A0A3P9DNQ3   A0A3B4FAU8   A0A3Q2Q9M6   A0A3Q2W676   A0A3Q1JUH6   A0A3B5B3E2   A0A3Q3GZQ0   A0A147A0T3   A0A3B4Y9S8   N6U9N4   A0A0F8ACM9   E6ZG47   A0A091I341   A0A3Q1C9B9   A0A401NYE2   G3P074   A0A3B4VMC3   A0A0S7HVT3   A0A1S3FTR9   A0A3B5RFN9   A0A087XLM6   A0A3B3XXJ9   A0A3B3U4K1   A0A3Q3MH21   E0VJI0   A0A1Y1L5E4   V9KWT3   A0A401SAA2   H2MQE0   A0A3Q1G422   A0A3L8DKV4   A0A026WGF9   A0A3P9KSA1   A0A3Q2ZAQ7   A0A3P9MVI9   A0A2U9BGI8   I3KTK6   A0A3Q2DPZ2   A0A3S2MCD1   A0A1S3L997   A0A3P9HFS6   A0A3B4VMC8   A0A218VCW3   A0A2I4BBN6   E1C1M8   F6R8M8   A0A151P9V2   W5MV18   A0A452IR59   A0A2K5ID15   A0A3B5JZ15   A0A1W4WHH3   A0A1A8IQP9   Q4VBI7   A0A1A8C6F6   A0A1A7ZQV6   A0A1A8EYI7   A0A023F083   A0A3B3RJ61   H3D095  

EC Number

3.1.-.-

Pubmed

19121390    23622113    26354079    28756777    22118469    26227816    + More
29403074    24845553    21347285    21719571    21282665    20798317    20634964    25186727    23537049    25835551    30297745    23542700    20566863    28004739    24402279    17554307    30249741    24508170    15592404    20431018    22293439    28562605    21551351    25474469    29240929    15496914   

EMBL

BABH01031549    GAIX01013945    JAA78615.1    GDQN01011333    JAT79721.1    KQ460882    + More
KPJ11492.1    KQ458981    KPJ04488.1    KZ150005    PZC75238.1    NWSH01000508    PCG75982.1    RSAL01000317    RVE42595.1    ODYU01002960    SOQ41124.1    AGBW02009157    OWR51496.1    JTDY01005870    KOB66532.1    PYGN01000551    PSN44400.1    NEVH01008208    PNF34624.1    PNF34626.1    KK852804    KDR16158.1    GEDC01020125    GEDC01017041    GEDC01016849    GEDC01003051    JAS17173.1    JAS20257.1    JAS20449.1    JAS34247.1    GECU01015899    JAS91807.1    GEBQ01014926    JAT25051.1    KQ435716    KOX79066.1    ADTU01020331    KQ976395    KYM93092.1    KQ979011    KYN26625.1    KQ982584    KYQ54405.1    GL888190    EGI65464.1    KQ977890    KYM98985.1    KQ981873    KYN34024.1    KZ288215    PBC32601.1    GECZ01008093    JAS61676.1    KQ414735    KOC62285.1    GL768105    EFZ12275.1    KQ435127    KZC14793.1    LBMM01002638    KMQ94539.1    GL452203    EFN77762.1    GU588261    ADO28217.1    GL438386    EFN69056.1    GCES01014498    JAR71825.1    APGK01043560    KB741015    KB632161    ENN75317.1    ERL89245.1    KQ042685    KKF11541.1    FQ310506    CBN81147.1    KL218144    KFP02637.1    BFAA01002888    GCB65889.1    GBYX01436381    JAO44959.1    AYCK01005639    AYCK01005640    DS235222    EEB13536.1    GEZM01066267    JAV68028.1    JW870607    AFP03125.1    BEZZ01000161    GCC27337.1    QOIP01000007    RLU20539.1    KK107238    EZA54781.1    CP026248    AWP03155.1    AERX01006897    CM012441    RVE72570.1    MUZQ01000010    OWK63688.1    AADN05000017    AAMC01088192    AAMC01088193    AAMC01088194    AAMC01088195    AAMC01088196    AAMC01088197    AAMC01088198    AAMC01088199    AAMC01088200    AKHW03000533    KYO45750.1    AHAT01001185    AHAT01001186    AHAT01001187    HAED01013205    HAEE01008207    SBQ99650.1    BC095763    AAH95763.1    HADZ01010707    HAEA01016296    SBP74648.1    HADY01006206    HAEJ01015231    SBP44691.1    HAEB01004392    SBQ50919.1    GBBI01003807    JAC14905.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000283053    UP000007151    + More
UP000037510    UP000245037    UP000235965    UP000027135    UP000053105    UP000005205    UP000078540    UP000078492    UP000075809    UP000007755    UP000078542    UP000078541    UP000242457    UP000005203    UP000053825    UP000076502    UP000036403    UP000221080    UP000008237    UP000261440    UP000000311    UP000265080    UP000261580    UP000265100    UP000265160    UP000261460    UP000265000    UP000264840    UP000265040    UP000261400    UP000261660    UP000261360    UP000019118    UP000030742    UP000054308    UP000257160    UP000288216    UP000007635    UP000261420    UP000081671    UP000002852    UP000028760    UP000261480    UP000261500    UP000261640    UP000009046    UP000287033    UP000001038    UP000257200    UP000279307    UP000053097    UP000265180    UP000264800    UP000242638    UP000246464    UP000005207    UP000265020    UP000087266    UP000265200    UP000197619    UP000192220    UP000000539    UP000008143    UP000050525    UP000018468    UP000291020    UP000233080    UP000005226    UP000192223    UP000000437    UP000261540    UP000007303   

PRIDE

H9JCC8   

Pfam

PF10496   Syntaxin-18_N        + More
PF07819   PGAP1
PF09757   Arb2

Interpro

IPR000727   T_SNARE_dom        + More
IPR010989   SNARE       
IPR029058   AB_hydrolase       
IPR019529   Syntaxin-18_N       
IPR019154   Arb2_domain       
IPR012908   PGAP1-like       
IPR006012   Syntaxin/epimorphin_CS       

SUPFAM

SSF53474   SSF53474        + More
SSF47661   SSF47661       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9JCC8   S4NY43   A0A1E1VYH1   A0A0N1IER1   A0A194QG14   A0A2W1BK28   + More
A0A2A4JX64   A0A3S2P5X2   A0A2H1VLK1   A0A212FCM4   A0A0L7KTD5   A0A2P8YJH0   A0A2J7R1B9   A0A067RBV0   A0A1B6CVB8   A0A1B6IXZ2   A0A1B6LMT0   A0A0M9A980   A0A158NM72   A0A195BWY4   A0A151JLI5   A0A151X1X5   F4WK14   A0A151IE89   A0A151JTN8   A0A2A3ENI4   A0A1B6GGX0   A0A088A105   A0A0L7QUJ3   E9J4J2   A0A154PSE5   A0A0J7KWA0   A0A2D0QAZ0   E2C2S7   A0A3B4C8D5   E3TD31   E2ABW1   A0A3P8S1C0   A0A3Q4HLZ3   A0A3P8PF05   A0A3P9DNQ3   A0A3B4FAU8   A0A3Q2Q9M6   A0A3Q2W676   A0A3Q1JUH6   A0A3B5B3E2   A0A3Q3GZQ0   A0A147A0T3   A0A3B4Y9S8   N6U9N4   A0A0F8ACM9   E6ZG47   A0A091I341   A0A3Q1C9B9   A0A401NYE2   G3P074   A0A3B4VMC3   A0A0S7HVT3   A0A1S3FTR9   A0A3B5RFN9   A0A087XLM6   A0A3B3XXJ9   A0A3B3U4K1   A0A3Q3MH21   E0VJI0   A0A1Y1L5E4   V9KWT3   A0A401SAA2   H2MQE0   A0A3Q1G422   A0A3L8DKV4   A0A026WGF9   A0A3P9KSA1   A0A3Q2ZAQ7   A0A3P9MVI9   A0A2U9BGI8   I3KTK6   A0A3Q2DPZ2   A0A3S2MCD1   A0A1S3L997   A0A3P9HFS6   A0A3B4VMC8   A0A218VCW3   A0A2I4BBN6   E1C1M8   F6R8M8   A0A151P9V2   W5MV18   A0A452IR59   A0A2K5ID15   A0A3B5JZ15   A0A1W4WHH3   A0A1A8IQP9   Q4VBI7   A0A1A8C6F6   A0A1A7ZQV6   A0A1A8EYI7   A0A023F083   A0A3B3RJ61   H3D095  

KEGG

101737678    K08492 syntaxin 18 | (RefSeq) syntaxin-18

PATHWAY

04130    SNARE interactions in vesicular transport - Bombyx mori (domestic silkworm)
04145    Phagosome - Bombyx mori (domestic silkworm)

GO

GO:0016020   GO:0016192   GO:0016021   GO:0015031   GO:0005789   GO:0016787   GO:0005623   GO:0005484   GO:0006886   GO:0090158   GO:1902953   GO:0019904   GO:1903358   GO:0005783   GO:1902117   GO:0031201   GO:0006890   GO:0005515   GO:0004386   GO:0003677   GO:0004003   GO:0005634   GO:0006289   GO:0016286  

Subcellular location

Endoplasmic reticulum membrane  

Length:

321

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.37588

Exp number, first 60 AAs:

0

Total prob of N-in:

0.84361

inside

1  -  296

TMhelix

297  -  319

outside

320  -  321

 

 

Pi

15.686666

Theta

20.134026

Tajima's D

-0.624381

CLR

1.03819

CSRT

0.212189390530473

Interpretation

Uncertain