Gene

KWMTBOMO12735  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007173

Annotation

PREDICTED:_UPF0528_protein_CG10038_[Amyelois_transitella]

Location

Bomo_Chr21(-):13549781-13552009      View in EpiBrowser

Full name

GPI inositol-deacylase      

Location in the cell

Cytoplasmic   Reliability : 1.292 Nuclear   Reliability : 1.556

CDS

ATGGAGGGAACGAAAACTATGAAGGAACTGGGATACATATTTGATTCAAATGGTCAAGTAAGAAAAATTGGAGCTGATGGACAGCCAACAGATGAACCATTCCAATTTGTTGTGAGCAATGATCACCAGGAATGCCAAGCTCATTATGAAGAACTTGGCTCAGCAATCACCAATTATGTTTATGATATTCTTCAGACTCAGATTGGATTGCAAAAGTTACCAATCCCAAAGGATTCAAATGATGGAACATTTATTTTTGTTTCAAAAGATTATGATAAAAAAGATGTTCTGTTAATATTGATTCACGGATCAGGCGTTGTGCGAGCTGGTCAGTGGGCTAGATCCCTCATAATCAATGAATCGTTGGACAAAGGATCTCAGATTCCGTATATCAAGAAGGCTTTGGCCAAAGACTATGGAGTAGTGGTACTAAATACAAATGACAATCACACAGCAGATGGAAAGACCATTCTCAACAGTAGCACCGCTGAGGAACATGCCCTTTACGCATGGCTGAACTACATATCCAATGCGAATGCAAGTTCCATACTCATTGTAGCACATAGTTATGGTGGGGTTGTCACGGTTTCTCTGGCAGAAGAGGTGCAAAATGACTTTGAAGACAGAGTAAAGGCCATTGCTTTTACTGACTCTGTACATTCCTATTCTAATAAGAAGCTTACAAACTTTTTGAAACAGGTTACAAAGAATTGGATATCTAGTCAGACACCGCTGGATACACCTCTCAGAACTCCTGATTTCGATATAACCAGACTTTCAGCAGGTCATGAGAAACATGAAATGACATCATACATGTGTATGGATTCTGTTTTTAAATACTTTGATGAAATACTAAATATGGATTAA

Protein

MEGTKTMKELGYIFDSNGQVRKIGADGQPTDEPFQFVVSNDHQECQAHYEELGSAITNYVYDILQTQIGLQKLPIPKDSNDGTFIFVSKDYDKKDVLLILIHGSGVVRAGQWARSLIINESLDKGSQIPYIKKALAKDYGVVVLNTNDNHTADGKTILNSSTAEEHALYAWLNYISNANASSILIVAHSYGGVVTVSLAEEVQNDFEDRVKAIAFTDSVHSYSNKKLTNFLKQVTKNWISSQTPLDTPLRTPDFDITRLSAGHEKHEMTSYMCMDSVFKYFDEILNMD

Description

Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

Similarity

Belongs to the GPI inositol-deacylase family.

Uniprot

H9JCC8   A0A2W1BJL6   A0A2A4JWV8   A0A2H1VLK1   A0A1E1W5T2   A0A3S2P5X2   + More
S4PXI8   A0A0N1I822   A0A194QGE3   A0A0L7KTD5   A0A212FCM4   A0A224XTD7   A0A069DRP7   A0A023F8K8   R4FN09   A0A1B0GIA4   B0WSG8   A0A1Q3FCJ1   A0A1Q3FCP4   A0A411G7X9   A0A182TET4   A0A084VBK7   A0A182UYC7   A0A182Q5K1   A0A182IL43   A0A182P044   A0A182HSS0   A0A182YHQ2   Q7PGI6   F5HKW1   A0A182XAW6   A0A182LEV6   A0A131Y220   B7PYI4   A0A0L0CCF9   V5IES4   A0A182NRN4   A0A182K6J9   Q1HR15   W5J797   Q174E7   Q174E8   A0A1S4FEX9   A0A1S4FF73   A0A182FSP5   A0A336LLT8   A0A0P4VZ19   A0A0P4VU20   A0A2M4APV3   A0A2M4AQI9   A0A293LNW8   A0A2M4AQC6   A0A067RS02   A0A0P5SS43   A0A034W0P5   A0A0P5IST6   A0A162C7I6   T1P8P1   A0A182H049   A0A0N8ACB7   A0A0A1WK31   A0A0N8B1E9   A0A1I8MQ93   A0A034W3A3   A0A2B4RGB0   W8BVI7   A0A0P4XF55   A0A0A1WHB7   A0A1V9XJ35   A0A0N8EKF4   W8B7Y2   A0A0P5ES30   A0A1I8NS57   A0A2R5LD69   A0A1S4EHA6   W8C535   A0A0P6DXZ8   E9FWJ2   A0A0K8VZ49   A0A0P5M204   A0A182SA10   A0A131YVS0   A0A182RS50   A0A224YFQ4   A0A1A9VBG1   L7M4Q1   A0A1B0B3Q7   A0A1A9WJG5   R7UDD5   Q295Q8   A0A182VWV0   A0A0R3NIV0   B4GFU3   A0A1B0G5F0   A0A0L8I9T8   A0A182MVT1   A0A0P5YTH7   K1R8U3   A0A3B0KKX4   A0A0P5QIN2  

EC Number

3.1.-.-

Pubmed

19121390    28756777    23622113    26354079    26227816    22118469    + More
26334808    25474469    24438588    25244985    12364791    14747013    17210077    20966253    26108605    25765539    17204158    20920257    23761445    17510324    24845553    25348373    26483478    25830018    25315136    24495485    28327890    21292972    26830274    28797301    25576852    23254933    15632085    17994087    22992520   

EMBL

BABH01031549    KZ150005    PZC75239.1    NWSH01000508    PCG75983.1    ODYU01002960    + More
SOQ41124.1    GDQN01008740    JAT82314.1    RSAL01000317    RVE42595.1    GAIX01004963    JAA87597.1    KQ460882    KPJ11493.1    KQ458981    KPJ04489.1    JTDY01005870    KOB66532.1    AGBW02009157    OWR51496.1    GFTR01005053    JAW11373.1    GBGD01002141    JAC86748.1    GBBI01001022    JAC17690.1    ACPB03020702    GAHY01001514    JAA75996.1    AJWK01013619    DS232071    EDS33826.1    GFDL01009768    JAV25277.1    GFDL01009725    JAV25320.1    MH366192    QBB02001.1    ATLV01008177    KE524456    KFB35351.1    AXCN02000007    APCN01000336    AAAB01008859    EAA44919.5    EGK96864.1    EGK96863.1    GEFM01003274    JAP72522.1    ABJB010210014    DS820118    EEC11656.1    JRES01000608    KNC29940.1    GANP01009682    JAB74786.1    DQ440279    ABF18312.1    ADMH02002125    ETN58740.1    CH477412    EAT41447.1    EAT41446.1    UFQS01000012    UFQT01000012    SSW97227.1    SSX17613.1    GDRN01096866    GDRN01096864    JAI59255.1    GDRN01096869    GDRN01096868    GDRN01096867    GDRN01096863    GDRN01096862    JAI59257.1    GGFK01009505    MBW42826.1    GGFK01009720    MBW43041.1    GFWV01004788    MAA29518.1    GGFK01009663    MBW42984.1    KK852460    KDR23485.1    GDIP01136106    JAL67608.1    GAKP01010723    JAC48229.1    GDIQ01208466    JAK43259.1    LRGB01001361    KZS12442.1    KA645141    AFP59770.1    JXUM01100744    KQ564594    KXJ72041.1    GDIP01161401    JAJ62001.1    GBXI01014888    JAC99403.1    GDIQ01222267    JAK29458.1    GAKP01010724    JAC48228.1    LSMT01000529    PFX16651.1    GAMC01009229    JAB97326.1    GDIP01242010    JAI81391.1    GBXI01016035    JAC98256.1    MNPL01009920    OQR73451.1    GDIQ01018036    JAN76701.1    GAMC01009230    JAB97325.1    GDIP01144156    JAJ79246.1    GGLE01003249    MBY07375.1    GAMC01009231    JAB97324.1    GDIQ01070626    JAN24111.1    GL732526    EFX87903.1    GDHF01018842    GDHF01008469    JAI33472.1    JAI43845.1    GDIQ01164641    JAK87084.1    GEDV01005967    JAP82590.1    GFPF01004659    MAA15805.1    GACK01005718    JAA59316.1    JXJN01007968    AMQN01008283    KB302699    ELU03974.1    CM000070    EAL28650.3    KRT00914.1    CH479182    EDW34478.1    CCAG010000308    KQ416193    KOF98261.1    AXCM01005500    GDIP01067017    JAM36698.1    JH818603    EKC30411.1    OUUW01000008    SPP84438.1    GDIQ01134645    JAL17081.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000053268    UP000037510    + More
UP000007151    UP000015103    UP000092461    UP000002320    UP000075902    UP000030765    UP000075903    UP000075886    UP000075880    UP000075885    UP000075840    UP000076408    UP000007062    UP000076407    UP000075882    UP000001555    UP000037069    UP000075884    UP000075881    UP000000673    UP000008820    UP000069272    UP000027135    UP000076858    UP000069940    UP000249989    UP000095301    UP000225706    UP000192247    UP000095300    UP000079169    UP000000305    UP000075901    UP000075900    UP000078200    UP000092460    UP000091820    UP000014760    UP000001819    UP000075920    UP000008744    UP000092444    UP000053454    UP000075883    UP000005408    UP000268350   

PRIDE

H9JCC8   

Pfam

PF10496   Syntaxin-18_N        + More
PF09757   Arb2
PF07819   PGAP1
PF00561   Abhydrolase_1
PF00326   Peptidase_S9
PF10189   Ints3

Interpro

IPR000727   T_SNARE_dom        + More
IPR010989   SNARE       
IPR029058   AB_hydrolase       
IPR019529   Syntaxin-18_N       
IPR019154   Arb2_domain       
IPR012908   PGAP1-like       
IPR000073   AB_hydrolase_1       
IPR001375   Peptidase_S9       
IPR019333   Int_cplx_su3       

SUPFAM

SSF53474   SSF53474        + More
SSF47661   SSF47661       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9JCC8   A0A2W1BJL6   A0A2A4JWV8   A0A2H1VLK1   A0A1E1W5T2   A0A3S2P5X2   + More
S4PXI8   A0A0N1I822   A0A194QGE3   A0A0L7KTD5   A0A212FCM4   A0A224XTD7   A0A069DRP7   A0A023F8K8   R4FN09   A0A1B0GIA4   B0WSG8   A0A1Q3FCJ1   A0A1Q3FCP4   A0A411G7X9   A0A182TET4   A0A084VBK7   A0A182UYC7   A0A182Q5K1   A0A182IL43   A0A182P044   A0A182HSS0   A0A182YHQ2   Q7PGI6   F5HKW1   A0A182XAW6   A0A182LEV6   A0A131Y220   B7PYI4   A0A0L0CCF9   V5IES4   A0A182NRN4   A0A182K6J9   Q1HR15   W5J797   Q174E7   Q174E8   A0A1S4FEX9   A0A1S4FF73   A0A182FSP5   A0A336LLT8   A0A0P4VZ19   A0A0P4VU20   A0A2M4APV3   A0A2M4AQI9   A0A293LNW8   A0A2M4AQC6   A0A067RS02   A0A0P5SS43   A0A034W0P5   A0A0P5IST6   A0A162C7I6   T1P8P1   A0A182H049   A0A0N8ACB7   A0A0A1WK31   A0A0N8B1E9   A0A1I8MQ93   A0A034W3A3   A0A2B4RGB0   W8BVI7   A0A0P4XF55   A0A0A1WHB7   A0A1V9XJ35   A0A0N8EKF4   W8B7Y2   A0A0P5ES30   A0A1I8NS57   A0A2R5LD69   A0A1S4EHA6   W8C535   A0A0P6DXZ8   E9FWJ2   A0A0K8VZ49   A0A0P5M204   A0A182SA10   A0A131YVS0   A0A182RS50   A0A224YFQ4   A0A1A9VBG1   L7M4Q1   A0A1B0B3Q7   A0A1A9WJG5   R7UDD5   Q295Q8   A0A182VWV0   A0A0R3NIV0   B4GFU3   A0A1B0G5F0   A0A0L8I9T8   A0A182MVT1   A0A0P5YTH7   K1R8U3   A0A3B0KKX4   A0A0P5QIN2  

PDB

5IKK     E-value=2.05197e-05,     Score=113

KEGG

101737392    no KO assigned | (RefSeq) protein FAM172A

GO

GO:0016020   GO:0016192   GO:0016021   GO:0015031   GO:0005789   GO:0016787   GO:0031048   GO:0005634   GO:0008236   GO:0016788   GO:0004521   GO:0042274   GO:0004386   GO:0005515   GO:0003677   GO:0004003   GO:0006289   GO:0016286  

PANTHER

PTHR13587  

Subcellular location

Endoplasmic reticulum membrane  

Length:

288

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.21513

Exp number, first 60 AAs:

9e-05

Total prob of N-in:

0.05960

outside

1  -  288

 

 

Pi

14.008655

Theta

14.683272

Tajima's D

0.071377

CLR

0

CSRT

0.400729963501825

Interpretation

Uncertain