Gene

KWMTBOMO12685  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001395

Annotation

proteasome_beta_3_subunit_[Bombyx_mori]

Location

Bomo_Chr21(-):11524305-11526262      View in EpiBrowser

Full name

Proteasome subunit beta      

Location in the cell

Cytoplasmic   Reliability : 1.024 Mitochondrial   Reliability : 1.089

CDS

ATGTCGATACTAGCGTATAACGGGGGTGCGGTAGTCGCCATGAAGGGCCAAGACTGTGTGGCCATCGCTACGGACAAGCGGTTTGGTATACAAGCTCAAACAGTATCAACCAACTTCCCAAAAGTATTCCAAATGGGACCCACATTGTATGTAGGCCTTCCCGGTCTCGCGACTGACACCCAAACTGTATTTCAGAGACTGAAATTTAGAATGAACTTGTATGAATTAAAAGAAAACAGAATGATGCGGCCTAAAACATTCTCAGCGATGTTGTCAAACTTATTGTATGAACGACGTTTCGGCCCTTACTTTATTGAACCTGTCATAGCTGGTCTAGATCCCTATGATAACCAACCTTATGTCTGTAACATGGACTTGATTGGTTGCCCAAATGAACCTGAAGATTTTGTGGTATCGGGCACCTGTTCTGAACAGCTGTATGGTATGTGTGAAGCTCTCTGGGAGCCCAACTTGAAGCCAGATGAACTCTTTGAGACAATCTCACAGGCTCTGGTGAATGCGGCAGATCGTGACGCCATCTCCGGTTGGGGTGCCGTTGTTTACATCATTGAAAAAGACAAGATCACTGAGAAACACGTCAAGACTAGGATGGATTAA

Protein

MSILAYNGGAVVAMKGQDCVAIATDKRFGIQAQTVSTNFPKVFQMGPTLYVGLPGLATDTQTVFQRLKFRMNLYELKENRMMRPKTFSAMLSNLLYERRFGPYFIEPVIAGLDPYDNQPYVCNMDLIGCPNEPEDFVVSGTCSEQLYGMCEALWEPNLKPDELFETISQALVNAADRDAISGWGAVVYIIEKDKITEKHVKTRMD

Catalytic Activity

Cleavage of peptide bonds with very broad specificity.

Subunit

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

Similarity

Belongs to the peptidase T1B family.

Feature

chain  Proteasome subunit beta

Uniprot

Q1HPR0   A0A2H1VUK5   A0A2A4JNY1   A0A437BUV0   A0A194RIQ5   A0A194QC19   + More
S4NT17   H9IVW4   A0A2P8YLE9   A0A067RJ92   A0A2J7RFJ1   A0A2T7PBT1   K7JC08   D2A5A1   A0A1W4XFI1   A0A0T6BAZ8   V4AJC9   V5GM13   A0A151WYL3   A0A151IIQ8   A0A195EYS2   A0A2C9JZ57   E9ICR6   A0A195BNA6   F4X523   A0A3S1BSJ8   A0A0B6ZG89   T1JN02   A0A026W287   J3JXN9   A0A1B6E894   E9HLR0   E2ALH3   A0A1Y1MF35   A0A0P5AFJ0   V9ILZ0   A0A088AMG0   A0A0P5T212   A0A232EM84   A0A0P5YKD4   A0A0P4Z770   A0A0P6INK4   A0A0P5Q6I9   A0A0N1IU27   A0A310SIZ8   A0A2A3EJE7   A0A0P5AND1   A0A0N8A073   C3YW11   A0A1B6MAX2   A0A1B6GER5   A0A1B6HFJ0   A0A0L8HDV8   B4KBU9   A0A1S3H261   A0A2M3ZH14   A0A2M4AFA9   Q5PQ24   A0A182Y3R1   A0A182T1G9   A0A182VZK3   A0A182QZP6   T1DPX8   A0A182LWJ0   D1GYZ2   D1GXV1   W5JEL5   Q5M999   A0A0A9XCS1   A0A182F7I3   A0A2M4AFX9   A0A182RIL9   A0A182NRV5   A0A0M4END8   A0A087SW53   A0A084VD39   A0A182V9Z4   A0A182TPX9   A0A182LA20   A0A182WSR4   Q7PY13   A0A182HLL8   A0A182JRZ2   A0A182PSK7   B4M460   Q294H4   B4GL36   A0A3B1JZ42   A0A182JN65   A0A023F968   B3M207   B4JFR3   A0A069DQ22   A0A0P4W204   R4FPU8   A0A3P8WJ28   A0A1Q3FCX8   B0W355   B4PTY8   B4HKX9  

EC Number

3.4.25.1

Pubmed

26354079    23622113    19121390    29403074    24845553    20075255    + More
18362917    19820115    23254933    15562597    21282665    21719571    24508170    30249741    22516182    23537049    21292972    20798317    28004739    28648823    18563158    17994087    27762356    25244985    20920257    23761445    25401762    26823975    24438588    20966253    12364791    14747013    17210077    15632085    25329095    25474469    26334808    27129103    24487278    17550304   

EMBL

DQ443342    ABF51431.1    ODYU01004363    SOQ44162.1    NWSH01000885    PCG73701.1    + More
RSAL01000006    RVE54244.1    KQ460325    KPJ15826.1    KQ459193    KPJ03098.1    GAIX01012351    JAA80209.1    BABH01006545    PYGN01000511    PSN45080.1    KK852439    KDR23887.1    NEVH01004413    PNF39598.1    PZQS01000005    PVD30870.1    AAZX01013508    KQ971345    EFA05105.1    LJIG01002438    KRT84502.1    KB201313    ESO97202.1    GALX01003347    JAB65119.1    KQ982649    KYQ52969.1    KQ977459    KYN02556.1    KQ981905    KYN33445.1    GL762354    EFZ21650.1    KQ976432    KYM87518.1    GL888680    EGI58480.1    RQTK01000101    RUS87774.1    HACG01020693    CEK67558.1    JH431954    KK107538    QOIP01000005    EZA49149.1    RLU23027.1    APGK01019082    BT128009    KB740092    KB632429    AEE62971.1    ENN81420.1    ERL95474.1    GEDC01003162    JAS34136.1    GL732680    EFX67334.1    GL440607    EFN65731.1    GEZM01037799    JAV81927.1    GDIP01199546    JAJ23856.1    JR050837    AEY61364.1    GDIP01132163    LRGB01002490    JAL71551.1    KZS07302.1    NNAY01003417    OXU19447.1    GDIP01070564    JAM33151.1    GDIP01218502    GDIP01194003    GDIP01154711    GDIP01061419    JAJ04900.1    GDIQ01002743    JAN91994.1    GDIQ01125207    JAL26519.1    KQ435711    KOX79601.1    KQ762882    OAD55362.1    KZ288248    PBC31151.1    GDIP01196452    JAJ26950.1    GDIP01195353    JAJ28049.1    GG666559    EEN55465.1    GEBQ01006920    JAT33057.1    GECZ01008845    JAS60924.1    GECU01034192    JAS73514.1    KQ418431    KOF87347.1    CH933806    EDW15801.1    GGFM01007073    MBW27824.1    GGFK01006007    MBW39328.1    BC087395    CM004483    AAH87395.1    OCT59933.1    AXCN02000250    GAMD01002934    JAA98656.1    AXCM01000082    FN546731    CBE67030.1    FN546340    FN546341    FN546342    FN546343    FN546344    FN546345    FN546346    FN546347    FN546348    FN546349    FN546350    FN546351    CBE66639.1    CBE66640.1    CBE66641.1    CBE66642.1    CBE66643.1    CBE66644.1    CBE66645.1    CBE66646.1    CBE66647.1    CBE66648.1    CBE66649.1    CBE66650.1    ADMH02001371    ETN62797.1    BC087457    CM004482    AAH87457.1    OCT62109.1    GBHO01028714    GBRD01003860    GDHC01015562    JAG14890.1    JAG61961.1    JAQ03067.1    GGFK01006368    MBW39689.1    CP012526    ALC47115.1    KK112225    KFM57092.1    ATLV01011146    KE524645    KFB35883.1    AAAB01008987    EAA00889.2    APCN01000909    CH940652    EDW59421.1    CM000070    EAL28990.1    CH479185    EDW38260.1    GBBI01000671    JAC18041.1    CH902617    EDV43331.1    CH916369    EDV93544.1    GBGD01002954    JAC85935.1    GDKW01000938    JAI55657.1    ACPB03009472    GAHY01000709    JAA76801.1    GFDL01009610    JAV25435.1    DS231830    EDS30763.1    CM000160    EDW96599.1    CH480815    EDW42943.1   

Proteomes

UP000218220    UP000283053    UP000053240    UP000053268    UP000005204    UP000245037    + More
UP000027135    UP000235965    UP000245119    UP000002358    UP000007266    UP000192223    UP000030746    UP000075809    UP000078542    UP000078541    UP000076420    UP000078540    UP000007755    UP000271974    UP000053097    UP000279307    UP000019118    UP000030742    UP000000305    UP000000311    UP000005203    UP000076858    UP000215335    UP000053105    UP000242457    UP000001554    UP000053454    UP000009192    UP000085678    UP000186698    UP000076408    UP000075901    UP000075920    UP000075886    UP000075883    UP000000673    UP000069272    UP000075900    UP000075884    UP000092553    UP000054359    UP000030765    UP000075903    UP000075902    UP000075882    UP000076407    UP000007062    UP000075840    UP000075881    UP000075885    UP000008792    UP000001819    UP000008744    UP000018467    UP000075880    UP000007801    UP000001070    UP000015103    UP000265120    UP000002320    UP000002282    UP000001292   

PRIDE

Q1HPR0    H9IVW4    A0A088AMG0   

Pfam

PF00227   Proteasome

Interpro

IPR033811   Proteasome_beta_3        + More
IPR023333   Proteasome_suB-type       
IPR001353   Proteasome_sua/b       
IPR016050   Proteasome_bsu_CS       
IPR029055   Ntn_hydrolases_N       

SUPFAM

SSF56235   SSF56235       

Gene 3D

3.60.20.10    

CDD

cd03759  proteasome_beta_type_3

ProteinModelPortal

Q1HPR0   A0A2H1VUK5   A0A2A4JNY1   A0A437BUV0   A0A194RIQ5   A0A194QC19   + More
S4NT17   H9IVW4   A0A2P8YLE9   A0A067RJ92   A0A2J7RFJ1   A0A2T7PBT1   K7JC08   D2A5A1   A0A1W4XFI1   A0A0T6BAZ8   V4AJC9   V5GM13   A0A151WYL3   A0A151IIQ8   A0A195EYS2   A0A2C9JZ57   E9ICR6   A0A195BNA6   F4X523   A0A3S1BSJ8   A0A0B6ZG89   T1JN02   A0A026W287   J3JXN9   A0A1B6E894   E9HLR0   E2ALH3   A0A1Y1MF35   A0A0P5AFJ0   V9ILZ0   A0A088AMG0   A0A0P5T212   A0A232EM84   A0A0P5YKD4   A0A0P4Z770   A0A0P6INK4   A0A0P5Q6I9   A0A0N1IU27   A0A310SIZ8   A0A2A3EJE7   A0A0P5AND1   A0A0N8A073   C3YW11   A0A1B6MAX2   A0A1B6GER5   A0A1B6HFJ0   A0A0L8HDV8   B4KBU9   A0A1S3H261   A0A2M3ZH14   A0A2M4AFA9   Q5PQ24   A0A182Y3R1   A0A182T1G9   A0A182VZK3   A0A182QZP6   T1DPX8   A0A182LWJ0   D1GYZ2   D1GXV1   W5JEL5   Q5M999   A0A0A9XCS1   A0A182F7I3   A0A2M4AFX9   A0A182RIL9   A0A182NRV5   A0A0M4END8   A0A087SW53   A0A084VD39   A0A182V9Z4   A0A182TPX9   A0A182LA20   A0A182WSR4   Q7PY13   A0A182HLL8   A0A182JRZ2   A0A182PSK7   B4M460   Q294H4   B4GL36   A0A3B1JZ42   A0A182JN65   A0A023F968   B3M207   B4JFR3   A0A069DQ22   A0A0P4W204   R4FPU8   A0A3P8WJ28   A0A1Q3FCX8   B0W355   B4PTY8   B4HKX9  

PDB

1IRU     E-value=1.23067e-86,     Score=811

KEGG

732999    K02735 20S proteasome subunit beta 3 [EC:3.4.25.1] | (RefSeq) proteasome beta 3 subunit

PATHWAY

03050    Proteasome - Bombyx mori (domestic silkworm)

GO

GO:0005737   GO:0005634   GO:0004298   GO:0043161   GO:0019774   GO:0004175   GO:0010498   GO:0010499   GO:0005839   GO:0000502   GO:0016021   GO:0051603   GO:0006428   GO:0000049   GO:0006508   GO:0016286  

PANTHER

PTHR11599:SF62  

Subcellular location

Cytoplasm  
Nucleus  

Length:

205

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.19842

Exp number, first 60 AAs:

0.16227

Total prob of N-in:

0.06927

outside

1  -  205

 

 

Pi

16.832272

Theta

15.936642

Tajima's D

-0.204903

CLR

0

CSRT

0.31938403079846

Interpretation

Uncertain