Silkworm Genome Informatics Database

Gene

KWMTBOMO12680 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001592

Annotation

vacuolar_ATP_synthase_subunit_D_[Bombyx_mori]

Location

Bomo_Chr21(+):11475913-11479303 View in EpiBrowser

Full name

V-type proton ATPase subunit D

Alternative Name

Vacuolar proton pump subunit D

Location in the cell

Cytoplasmic Reliability : 1.487 Mitochondrial Reliability : 1.153 Nuclear Reliability : 1.516

CDS

ATGAATATTGAAAATCGTTATCAAGTGACGGCTTCCCTGTTCATGTTAAAAGAAATAAAGCGCAGACAAGAACACGTAGATCGGGGCTATGAGCTTTTGAAAAGAAAAGCTGAGGGTCTACGAATTAAAGGTAGACAAGTGGCCTCGGAACTTATCGCAACTCATGGGCTGTTGAGCCATAAAATGAAAGAAGCTTACATGTCACTAGCGGCTATTAAGTTTACAAACGGAGAATCGAATGCATTGGTGCTTGAGAATGTCGAGCAGGCTCAAATACGTGTTCAGCGAATCACTGAGAATGTCTCGGGTGTTACGACGACGTACTTAGAAGCCGTCGAAGAGACAGGTGTGACTAATGCTCTTCAATACGCTGGCTTGGGCGCTGGTGGTCACCGCACCAGTGAGGCAAAGAAATCATTCAGAGAGGCCGTGCATCTTGTATTGAAGCTGGCATCTTTGAGAAAGACCTGCGTGCTACTGGACGAAGCTATTAGGATCGCCTGGAGGAAAGTCAATGGAATAGAAAAGGTCATTATGCCTAAATTGCGTAACACAGAACACTATATACTAGTCGAGATAGACGAATGCGAGAGGGAAGAATTTCATCGACTCAAGATGGTAAAAGCTAAAAAGTTAAAAAACAAAGCAATGGCTGTACATAAACCAATTAATCGACAAGGCGGTGATCACAGTGTATTGGATAGCAAGCCTTTGGTCCTGTCTTATGAAAAGTCTTCGGATGTTCTAATGAGCGTTTTACATCCGTGTCAGTCGTTGACCTCTTCGAGTGTATCTTTTGGAGACTGCAAGCCAATTTGCTACCCTCATAATTGGGATGACGATGATTTATTATTTTAG

Protein

MNIENRYQVTASLFMLKEIKRRQEHVDRGYELLKRKAEGLRIKGRQVASELIATHGLLSHKMKEAYMSLAAIKFTNGESNALVLENVEQAQIRVQRITENVSGVTTTYLEAVEETGVTNALQYAGLGAGGHRTSEAKKSFREAVHLVLKLASLRKTCVLLDEAIRIAWRKVNGIEKVIMPKLRNTEHYILVEIDECEREEFHRLKMVKAKKLKNKAMAVHKPINRQGGDHSVLDSKPLVLSYEKSSDVLMSVLHPCQSLTSSSVSFGDCKPICYPHNWDDDDLLF

Description

Subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity).

Subunit

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).

Similarity

Belongs to the V-ATPase D subunit family.

Keywords

Hydrogen ion transport Ion transport Transport

Feature

chain V-type proton ATPase subunit D

Uniprot

Q1HPT6 A0A2A4JPL8 A0A3S2M9Q5 A0A194QC24 A0A212F797 A0A194RIQ1 + More
A0A2H1VDR4 A0A0K8R796 A0A2R5LLI9 A0A1X7V4P9 L7M572 A0A131YAH9 A0A1Z5L7E6 A0A131XDI4 A0A182MBX6 A0A2L2XWR5 P57747 A0A293MZR3

Pubmed

19121390 26354079 22118469 25576852 28528879 28049606 + More
26561354

EMBL

BABH01006541 DQ443316 ABF51405.1 NWSH01000885 PCG73706.1 RSAL01000006 + More
RVE54249.1 KQ459193 KPJ03103.1 AGBW02009897 OWR49612.1 KQ460325 KPJ15821.1 ODYU01002009 SOQ38978.1 GADI01006783 JAA67025.1 GGLE01006246 MBY10372.1 GACK01005864 JAA59170.1 GEFM01000304 JAP75492.1 GFJQ02004059 JAW02911.1 GEFH01004421 JAP64160.1 AXCM01002501 IAAA01003490 IAAA01003491 IAAA01003492 LAA00509.1 AJ297976 GFWV01019917 MAA44645.1

Proteomes

UP000005204 UP000218220 UP000283053 UP000053268 UP000007151 UP000053240 + More
UP000007879 UP000075883

PRIDE

Q1HPT6 L7M572 P57747

Pfam

PF01813 ATP-synt_D

Interpro

IPR002699 V_ATPase_D

ProteinModelPortal

Q1HPT6 A0A2A4JPL8 A0A3S2M9Q5 A0A194QC24 A0A212F797 A0A194RIQ1 + More
A0A2H1VDR4 A0A0K8R796 A0A2R5LLI9 A0A1X7V4P9 L7M572 A0A131YAH9 A0A1Z5L7E6 A0A131XDI4 A0A182MBX6 A0A2L2XWR5 P57747 A0A293MZR3

PDB

6O7X E-value=2.14416e-26, Score=294

KEGG

733120 K02149 V-type H+-transporting ATPase subunit D | (RefSeq) vacuolar ATP synthase subunit D

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04145    Phagosome - Bombyx mori (domestic silkworm)
04150    mTOR signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0042626 GO:0006811 GO:0008270 GO:0006355 GO:0042132 GO:0042578 GO:0044249 GO:0006428 GO:0000049 GO:0006508 GO:0016286

PANTHER

PTHR11671

Length:

285

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00329

Exp number, first 60 AAs:

0.00093

Total prob of N-in:

0.14474

outside

1 - 285

Pi

30.982109

Theta

24.912156

Tajima's D

0.711097

CLR

0.224122

CSRT

0.582570871456427

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics