Gene

KWMTBOMO12669

Pre Gene Modal

BGIBMGA001578

Annotation

hypothetical_protein_KGM_17018_[Danaus_plexippus]

Location

Bomo_Chr21(+):11140583-11144334      View in EpiBrowser

Full name

Glucose-6-phosphate isomerase      

Location in the cell

PlasmaMembrane   Reliability : 4.894

CDS

ATGTCGGTTGATTATACAATTTCAAGAAATCTAAGAGATGGAGGTATAGGAACGAGGCCTATCTCAAGCAACGGGTTATGGTGTTGTGCTTTACTGCCCGCATTATTAATCTCATACAATTTTTTGTACAAAGTGTCGCCACTTTATACACTAGTAGCTTACGTAGCTGTTGGTTTATTCTGCTACAGCATACTGTTTGTGGTATTCATTTCTGTATCATGTCTGGTACTCAGAGAGCCTATCTATGGAGGATGTATAGCATCTAGTCTTGTATCTGCTCTGATGAATTTTATATTTAATACACAAGGTTTAACAACATCATTGTCTTTCTCCCTCACAGCAGTGTACTTATATAGTACAATGCTAAGATGGTCTCTCACCAAATTCCCAAAGACATACACTATAGGAGAAGCCATGATTGTAACACAGGGTTTGACTTTATTCACCATTGCAGTTATTGGAAGGACCATGAATATATTACATGATCCTAACGAAGACATGAATTTAATAAGCAGCATTGTGCTTACAGCATTATCAACGGTTGGATTACTTATTACAGGTTTATGTGTGATATCGGAAAAACAAAGAAACATACAAACATTTAGTTATATGTTTGCAGTGGCTGCTTTGTTTGCTTTAGTCACCTTACATGTACTACTAGGATTAAATTGTGTATTCCGGATACTGAACTATATTTTTCTGAACCGAAACAGAGTTCAACTATTTGCGTTCTGGTTATTTCTACTTATGATATCTGTATTTTTGGTACTTACGCGAACCAAAAGTGCTGTAAAGGTGAATACTGTGACCAGAAAATCATTTCATTTATTGGCCTCGCTTGTTTTTATGTCAGGTATTATTTATGATGTTTATCTGACGAGCCTGGCTGCTGGAATTGGATTTGGATTGTTGATTTTAGTCGAGGCATTACGTAAGTTAAACATCACACCAATATCAGAAGCCCTGCAATCAGCTTTTGATGTCTACAGTGATGAGAAGGACATAGGAAGTTTCGCGATGACACCGATCTACTTGTATGTAGGCTTAGCATGTCCATTGATACTGGTGCCTAGTTATGAAGGAACAACTCTTGAGCTGCTCAGCGGAGTCCTCGCAACTGGGGTAGGAGATACAGCTGCCAGTTGGTTCGGTTCCAAATACGGCACGAAGAAGTGGACTAATAGTGAAAAAACAGTGGAGGGAACAATTGCTAATGTCTTGTCACAAGTTGCAACGGTTTATGTTTTGCATTTATTTGGTCTTCTAAGAAACAACACTGTGTTAATTAGAACGATGTTAGCTGCATCAATATCCAGTGTGGTCGAAGCGAAAACGGATCAGGTCGACAACCTAATACTTCCTCTAGTCACATTGTTAGTGTTTCAAATAAATTGGATGTTCGGCTAG

Protein

MSVDYTISRNLRDGGIGTRPISSNGLWCCALLPALLISYNFLYKVSPLYTLVAYVAVGLFCYSILFVVFISVSCLVLREPIYGGCIASSLVSALMNFIFNTQGLTTSLSFSLTAVYLYSTMLRWSLTKFPKTYTIGEAMIVTQGLTLFTIAVIGRTMNILHDPNEDMNLISSIVLTALSTVGLLITGLCVISEKQRNIQTFSYMFAVAALFALVTLHVLLGLNCVFRILNYIFLNRNRVQLFAFWLFLLMISVFLVLTRTKSAVKVNTVTRKSFHLLASLVFMSGIIYDVYLTSLAAGIGFGLLILVEALRKLNITPISEALQSAFDVYSDEKDIGSFAMTPIYLYVGLACPLILVPSYEGTTLELLSGVLATGVGDTAASWFGSKYGTKKWTNSEKTVEGTIANVLSQVATVYVLHLFGLLRNNTVLIRTMLAASISSVVEAKTDQVDNLILPLVTLLVFQINWMFG

Catalytic Activity

aldehydo-D-glucose 6-phosphate = keto-D-fructose 6-phosphate

Similarity

Belongs to the GPI family.

Uniprot

A0A2A4J010   A0A437BUW5   A0A212EK38   A0A2H1VR11   A0A1E1WDM3   A0A151IR70   + More
A0A158NUT6   F4WE33   A0A195BBG0   A0A151K0H3   A0A0A9X6W9   A0A151X4A0   A0A195CPG8   A0A067QG69   E2BJL3   B4MNV0   A0A026VWV9   A0A2J7RJT4   A0A3B0JP85   A0A1S4G712   B4GDA5   A0A023EX59   Q292L0   B3NPG7   N6SVE6   B4P5Y3   B3MDK7   A0A0L7RJR9   A0A139WMS4   A0A1B6D909   A0A1Y1KPY0   A0A154PLF5   A0A1L8DYD5   A0A2S2QB13   A0A3L8D633   A0A2S2Q3P1   A0A1Q3FCU4   A1ZAI1   B0W6U1   A0A1I8NE03   B4HT64   B5RIH4   B4QI11   A0A232ERN2   A0A0A1X8W1   K7J469   A0A1W4UKF2   A0A336KFT3   A0A336M1G4   A0A0L0BLT5   A0A182GZ47   B4J701   A0A1A9WJ03   A0A2P6L2B9   A0A0K8U0S0   A0A1J1IF95   A0A0K8UUQ8   A0A1I8NZP9   B4LLI1   A0A2A3EJG4   A0A1I8NZP6   A0A1B0AHR1   A0A1A9V5B3   A0A0K8VA74   A0A2J7RJV1   A0A1B0FMZ6   A0A023EU31   J9JRT5   W8ATC5   A0A182J380   A0A1J1IDN9   A0A1A9Y2Y5   A0A1B0B070   B4KRG2   A0A087ZPV5   A0A147BPS2   A0A1E1X696   A0A224YNK7   A0A310SRP9   W5JTC5   A0A131Y165   L7ML28   W8BS61   A0A182UQ80   A0A131XG60   Q7QCL2   A0A182HSA4   B7P8K5   A0A2M4APB2   A0A2M4APR8  

EC Number

5.3.1.9

Pubmed

22118469    21347285    21719571    25401762    26823975    24845553    + More
20798317    17994087    24508170    25474469    15632085    23185243    23537049    17550304    18362917    19820115    28004739    30249741    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25315136    22936249    28648823    25830018    20075255    26108605    26483478    24945155    24495485    29652888    28503490    28797301    20920257    23761445    25576852    28049606    12364791    14747013    17210077   

EMBL

NWSH01004755    PCG64703.1    RSAL01000006    RVE54263.1    AGBW02014323    OWR41859.1    + More
ODYU01003897    SOQ43228.1    GDQN01005995    GDQN01001206    JAT85059.1    JAT89848.1    KQ981144    KYN09154.1    ADTU01026698    GL888102    EGI67471.1    KQ976532    KYM81534.1    KQ981296    KYN43110.1    GBHO01027137    GBRD01003130    GDHC01018861    JAG16467.1    JAG62691.1    JAP99767.1    KQ982557    KYQ55048.1    KQ977481    KYN02387.1    KK853510    KDR07080.1    GL448571    EFN84170.1    CH963848    EDW73789.2    KK107722    EZA48006.1    NEVH01002988    PNF41090.1    OUUW01000001    SPP74471.1    CH479181    EDW31581.1    GBBI01004777    JAC13935.1    CM000071    EAL24852.1    KRT01628.1    CH954179    EDV55734.1    APGK01055062    KB741259    ENN71694.1    CM000158    EDW91899.1    CH902619    EDV37470.1    KQ414579    KOC71115.1    KQ971312    KYB29183.1    GEDC01015117    GEDC01012662    GEDC01007329    GEDC01003955    JAS22181.1    JAS24636.1    JAS29969.1    JAS33343.1    GEZM01077271    JAV63344.1    KQ434967    KZC12699.1    GFDF01002665    JAV11419.1    GGMS01005713    MBY74916.1    QOIP01000012    RLU15704.1    GGMS01003145    MBY72348.1    GFDL01009649    JAV25396.1    AE013599    AAF57978.1    DS231849    EDS36922.1    CH480816    EDW48165.1    BT044098    ACH92163.1    CM000362    CM002911    EDX07382.1    KMY94297.1    NNAY01002569    OXU21029.1    GBXI01007174    JAD07118.1    AAZX01011384    UFQS01000316    UFQT01000316    SSX02772.1    SSX23143.1    UFQT01000289    SSX22839.1    JRES01001669    KNC21016.1    JXUM01098672    KQ564439    KXJ72269.1    CH916367    EDW00989.1    MWRG01002363    PRD32734.1    GDHF01031995    JAI20319.1    CVRI01000047    CRK97670.1    GDHF01022003    JAI30311.1    CH940648    EDW61933.2    KZ288238    PBC31339.1    GDHF01016844    GDHF01006301    JAI35470.1    JAI46013.1    PNF41089.1    CCAG010017066    GAPW01001172    JAC12426.1    ABLF02013049    ABLF02013050    ABLF02013051    GAMC01014490    JAB92065.1    CRK97668.1    JXJN01006586    CH933808    EDW09378.1    GEGO01002636    JAR92768.1    GFAC01004460    JAT94728.1    GFPF01007369    MAA18515.1    KQ760832    OAD58880.1    ADMH02000547    ETN65984.1    GEFM01004030    JAP71766.1    GACK01001051    JAA63983.1    GAMC01014491    JAB92064.1    GEFH01002582    JAP65999.1    AAAB01008859    EAA07721.4    APCN01000256    ABJB010214712    DS658362    EEC02927.1    GGFK01009276    MBW42597.1    GGFK01009277    MBW42598.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000078492    UP000005205    UP000007755    + More
UP000078540    UP000078541    UP000075809    UP000078542    UP000027135    UP000008237    UP000007798    UP000053097    UP000235965    UP000268350    UP000008744    UP000001819    UP000008711    UP000019118    UP000002282    UP000007801    UP000053825    UP000007266    UP000076502    UP000279307    UP000000803    UP000002320    UP000095301    UP000001292    UP000000304    UP000215335    UP000002358    UP000192221    UP000037069    UP000069940    UP000249989    UP000001070    UP000091820    UP000183832    UP000095300    UP000008792    UP000242457    UP000092445    UP000078200    UP000092444    UP000007819    UP000075880    UP000092443    UP000092460    UP000009192    UP000005203    UP000000673    UP000075903    UP000007062    UP000075840    UP000001555   

PRIDE

A1ZAI1   

Pfam

PF00342   PGI        + More
PF00400   WD40

Interpro

IPR032974   Polypren_kinase        + More
IPR026566   DOLK       
IPR018189   Phosphoglucose_isomerase_CS       
IPR001672   G6P_Isomerase       
IPR035476   SIS_PGI_1       
IPR023096   G6P_Isomerase_C       
IPR035482   SIS_PGI_2       
IPR001680   WD40_repeat       
IPR001632   Gprotein_B       
IPR017986   WD40_repeat_dom       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR036322   WD40_repeat_dom_sf       
IPR019775   WD40_repeat_CS       
IPR016346   Guanine_nucleotide-bd_bsu       
IPR020472   G-protein_beta_WD-40_rep       

SUPFAM

SSF50978   SSF50978       

Gene 3D

1.10.1390.10     2.130.10.10    

CDD

cd05015  SIS_PGI_1
cd05016  SIS_PGI_2

ProteinModelPortal

A0A2A4J010   A0A437BUW5   A0A212EK38   A0A2H1VR11   A0A1E1WDM3   A0A151IR70   + More
A0A158NUT6   F4WE33   A0A195BBG0   A0A151K0H3   A0A0A9X6W9   A0A151X4A0   A0A195CPG8   A0A067QG69   E2BJL3   B4MNV0   A0A026VWV9   A0A2J7RJT4   A0A3B0JP85   A0A1S4G712   B4GDA5   A0A023EX59   Q292L0   B3NPG7   N6SVE6   B4P5Y3   B3MDK7   A0A0L7RJR9   A0A139WMS4   A0A1B6D909   A0A1Y1KPY0   A0A154PLF5   A0A1L8DYD5   A0A2S2QB13   A0A3L8D633   A0A2S2Q3P1   A0A1Q3FCU4   A1ZAI1   B0W6U1   A0A1I8NE03   B4HT64   B5RIH4   B4QI11   A0A232ERN2   A0A0A1X8W1   K7J469   A0A1W4UKF2   A0A336KFT3   A0A336M1G4   A0A0L0BLT5   A0A182GZ47   B4J701   A0A1A9WJ03   A0A2P6L2B9   A0A0K8U0S0   A0A1J1IF95   A0A0K8UUQ8   A0A1I8NZP9   B4LLI1   A0A2A3EJG4   A0A1I8NZP6   A0A1B0AHR1   A0A1A9V5B3   A0A0K8VA74   A0A2J7RJV1   A0A1B0FMZ6   A0A023EU31   J9JRT5   W8ATC5   A0A182J380   A0A1J1IDN9   A0A1A9Y2Y5   A0A1B0B070   B4KRG2   A0A087ZPV5   A0A147BPS2   A0A1E1X696   A0A224YNK7   A0A310SRP9   W5JTC5   A0A131Y165   L7ML28   W8BS61   A0A182UQ80   A0A131XG60   Q7QCL2   A0A182HSA4   B7P8K5   A0A2M4APB2   A0A2M4APR8  

KEGG

101745247    K00902 dolichol kinase [EC:2.7.1.108] | (RefSeq) dolichol kinase

PATHWAY

00510    N-Glycan biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004168   GO:0016021   GO:0043048   GO:0030176   GO:0006094   GO:0006096   GO:0004347   GO:0007165   GO:0016301  

PANTHER

PTHR13205:SF15   PTHR13205   PTHR11469   PTHR19850  

Length:

468

Number of predicted TMHs:

12

Exp number of AAs in TMHs:

265.76298

Exp number, first 60 AAs:

32.59357

Total prob of N-in:

0.95791

POSSIBLE N-term signal

sequence

inside

1  -  20

TMhelix

21  -  43

outside

44  -  52

TMhelix

53  -  75

inside

76  -  79

TMhelix

80  -  99

outside

100  -  103

TMhelix

104  -  126

inside

127  -  132

TMhelix

133  -  154

outside

155  -  168

TMhelix

169  -  191

inside

192  -  203

TMhelix

204  -  226

outside

227  -  240

TMhelix

241  -  258

inside

259  -  278

TMhelix

279  -  301

outside

302  -  334

TMhelix

335  -  357

inside

358  -  363

TMhelix

364  -  383

outside

384  -  402

TMhelix

403  -  422

inside

423  -  468

 

 

Pi

16.560539

Theta

21.096077

Tajima's D

-0.58949

CLR

2.231543

CSRT

0.218839058047098

Interpretation

Uncertain