Gene

KWMTBOMO12653

Pre Gene Modal

BGIBMGA001572

Annotation

PREDICTED:_probable_ATP-dependent_RNA_helicase_DHX34_[Bombyx_mori]

Location

Bomo_Chr21(+):10295165-10318598      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit M      

Location in the cell

Nuclear   Reliability : 4.101

CDS

ATGAGCTACGACCCGACATCGAAGATGCAGAGGTTAAAAGAGTTTTGGATATCGAAGGCCAGCGCCGACCAAAGGAAAGGTCGTGCCGGAAGAACGGGTCCCGGCGTCTGCTATAGGATATATTCCGAACAACAGTACACGGATATGGAGCCGTTCAGTACTCCAGAGGTGTCCAGGGTCCCGCTGGCCTCTCTGCTCCTGTTGATGAGCTCTTTAGGGGTGAACGACGTCAGGCGCTTCCCTTTCATCGATACTCCGCCCGAGGAGAGCATCGAGAATGCTCTGTTGGAGCTCAAACAGCATGGCGCTTTAACATCGAACGAGAAATTAACAGCGCTAGGGAAAGCTTTATCGAATCTGCCAGTTGAAGTTTCATTAGCGAAAGCTCTGGTCATCGGGAGCGCAACTTTACAGACGCACAAGAGAGACTCTGCTCTCGCGTTGACCGCCGCTTTAGGGATTCGTTCCATTTTCACCACTAGAGCGCACCGAGATTTCGATTGTGAGAATGCAAGGAAGCCTGATGAATCAGACCACGGCGACCCGCTGACATTACTGTCCTTGTACTGCGCTTGGTTGCGTGTCAAAGCCGAGGAGCGCGGCGGGAGAAGCTGGTGCAAGAGGCGGGGCATCGAGGAACAGCGACTTTACGAGCTGACTAAATTGGCGGCACAACTAAGGGGCCTCTTGCAGGACAACAATCTATCTGAGACTCCTGAACCGGAGACGATGTCTTCAGCGGAGAGGGCGTTACGTCACGGCCAGATGAAACAGCTCAAGGACATGAGGAGGCAATACAAACAGAAATCGGCTGAAGATTCGAAACGCAAGAAACGTTTGAAGATAGACTCGTGGGAGATCGTCGACGAGAATGAGAACGAGGATGACAATGTTTTCGATATAAGGGACATTGAATTCCGTATGAGCAACGACGCTCAGAGGATCCAGGCTCTGATATCCGGCTCCAGCGCGTCCAGTGGACGGGACCTTGTCATGCTGAAGATTGTGTTAGCCAGAGCGCTGTACCCACAAGTAGCAGTTGCCGATGAATTCAATTATTGCAAGTCCGTAGCCGAACAATTGTACCACACTTGGAGTAAGCCCTTCGTGTTCCTACACCCCACCTCGTATTTCGGGAAGCAGCCCCGCGTGCTGATGCTGACGGAGGCGGACATACAGACGGACCCGCCCGCCGGGTACAAGAGTAAACTACCCTTGTCAGCAAAACACCAGTTACTGTGTTATTTGTCTCTGCTCGAAACAACTAAGCCGTACATTGTGAATTCCATGAGGATGCCGGCCGCACAGACCCTGCTGCTATTGGCGCATTCCATTGATACCAATATAGGATTTACAAGGATAGTATGTGACTCGTGGCTCCTGTTGGAGTTTCCTTATCCTGAAACCGGGTTAAATCTGCTGATGAAAGCTGTTAGGCTGAGACGGAGGTGGAACGATCTGGTGAACCGACGACTTGCAGACGCGAACCCAGCGAAGACCGTGGAATCGGAATTGGAGAAACAGAAGCACTCAAAGTCGTCGTACGAGGAAACACAGTACGAGCTGTCCTGCGATATCAGTTCGTACATGAACAGCGAAGTTTATTATACGATCAAGAGATTACTACCGGGCGACCTAAAGATATTGTACTACGGTAATGATGAAGCGCATCCAAATATCGACCCTAATCCGTTCGAAGAAGGCTTCGAATGTCGACCTCACGAGAAGAAAGGCGGTGTCTACGTCACCGATAATATCGTTTATAATTGCGTCGTCGACACAGATTGGAGTTACAACACGTACCAAGAAACTTATGGTTTACCTTGGACGTGTGAGAAATGCGAGATGTCGATGTGTCTGTCGCCGCTGGAGAGACTGCAACACAAACTGTTCACTTGTTCGGCGAGAGCGGTGAAAGAGGAACCCGGCCCTAGTAAAACTGTAAAGGAGAATAAACCTAATTGCAAGGAGTTTAAGTGCGAGAATTGCGAGGCGGTTTTGTATTCGACTCCGGTCGATATATTGAGACATAAGAAAACGTGTAAAAAGAAATAA

Protein

MSYDPTSKMQRLKEFWISKASADQRKGRAGRTGPGVCYRIYSEQQYTDMEPFSTPEVSRVPLASLLLLMSSLGVNDVRRFPFIDTPPEESIENALLELKQHGALTSNEKLTALGKALSNLPVEVSLAKALVIGSATLQTHKRDSALALTAALGIRSIFTTRAHRDFDCENARKPDESDHGDPLTLLSLYCAWLRVKAEERGGRSWCKRRGIEEQRLYELTKLAAQLRGLLQDNNLSETPEPETMSSAERALRHGQMKQLKDMRRQYKQKSAEDSKRKKRLKIDSWEIVDENENEDDNVFDIRDIEFRMSNDAQRIQALISGSSASSGRDLVMLKIVLARALYPQVAVADEFNYCKSVAEQLYHTWSKPFVFLHPTSYFGKQPRVLMLTEADIQTDPPAGYKSKLPLSAKHQLLCYLSLLETTKPYIVNSMRMPAAQTLLLLAHSIDTNIGFTRIVCDSWLLLEFPYPETGLNLLMKAVRLRRRWNDLVNRRLADANPAKTVESELEKQKHSKSSYEETQYELSCDISSYMNSEVYYTIKRLLPGDLKILYYGNDEAHPNIDPNPFEEGFECRPHEKKGGVYVTDNIVYNCVVDTDWSYNTYQETYGLPWTCEKCEMSMCLSPLERLQHKLFTCSARAVKEEPGPSKTVKENKPNCKEFKCENCEAVLYSTPVDILRHKKTCKKK

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Similarity

Belongs to the eIF-3 subunit M family.

Uniprot

H9IWE1   A0A194RIL9   A0A194QCI8   A0A437BVI8   A0A2A4JIC2   A0A2H1VVT9   + More
A0A2H1WG22   E2BBB5   A0A0L7RFZ6   E9IA45   A0A154P2V7   A0A195ED09   A0A3L8E3F6   A0A026W426   A0A151JX31   F4X447   A0A0N0BHN3   A0A087ZVP3   A0A2A3E913   A0A310SER1   Q16ZW5   A0A182Q8L6   A0A232ELE6   K7IZR6   A0A182NSC3   A0A182F869   A0A182VR46   A0A182YGA7   A0A067QZV6   A0A182H8U1   A0A182JQJ0   A0A182RXI4   A0A1S4GCB0   Q7PXC6   A0A182L8W0   A0A182T6X9   W5J946   A0A182U3Q7   A0A182PSG2   A0A182X9N5   A0A182VJV8   E2A8T0   A0A2C9GQI6   A0A084VS66   A0A2J7QV15   A0A182J6Q0   A0A2J7QV18   A0A182MDT4   A0A151HZP2   A0A1B6D6A9   A0A0J7NJI1   B0XEL6   A0A2P8YLP0   A0A151WRX8   A0A336LMF3   A0A1B6GWG1   A0A1J1IBQ6   J9K3B6   A0A034VIS3   W8AWC2   A0A2J7QV12   A0A2S2QVX1   A0A0A1XG36   A0A1B6EK33   A0A0K8U1W1   A0A146L351   A0A0A9XYB6   A0A023F2W4   A0A1I8NLN9   A0A224XAE4   E9GJF2   A0A0P5HVU0   A0A0P5QV34   A0A0P5MVP6   A0A0P5VEA8   A0A0P6CJ48   A0A0P4YE01   A0A0V0GAR2   A0A0P5B119   A0A1A9WXX5   A0A0P5LCN2   A0A0P6GGA5   B4NPI6   A0A0P5IYB9   A0A151IDH4   A0A1A9XAY2   A0A1A9UY04   A0A1S4ESB8   A0A2S2Q2J9   A0A0P5UEA8   A0A1B0BK13   B4JX25   B4PZI5   T1HSD3   B3NVN1   A0A0P6FCC7   A0A0P5ZKG5  

Pubmed

19121390    26354079    20798317    21282665    30249741    24508170    + More
21719571    17510324    28648823    20075255    25244985    24845553    26483478    12364791    20966253    20920257    23761445    24438588    29403074    25348373    24495485    25830018    26823975    25401762    25474469    21292972    17994087    17550304   

EMBL

BABH01006434    BABH01006435    BABH01006436    BABH01006437    BABH01006438    KQ460325    + More
KPJ15791.1    KQ459193    KPJ03134.1    RSAL01000006    RVE54271.1    NWSH01001367    PCG71516.1    ODYU01004750    SOQ44961.1    ODYU01008430    SOQ52030.1    GL446968    EFN87023.1    KQ414599    KOC69749.1    GL761987    EFZ22560.1    KQ434808    KZC06163.1    KQ979074    KYN23088.1    QOIP01000001    RLU27280.1    KK107447    EZA50758.1    KQ981607    KYN39402.1    GL888625    EGI58771.1    KQ435750    KOX76241.1    KZ288327    PBC27954.1    KQ769895    OAD52775.1    CH477482    EAT40211.1    AXCN02000207    NNAY01003583    OXU19151.1    KK853055    KDR11967.1    JXUM01029658    KQ560860    KXJ80603.1    AAAB01008987    EAA01125.4    ADMH02002026    ETN59898.1    GL437663    EFN70159.1    APCN01000846    ATLV01015825    KE525036    KFB40810.1    NEVH01010479    PNF32426.1    PNF32425.1    AXCM01016731    KQ976687    KYM78133.1    GEDC01016074    GEDC01014764    JAS21224.1    JAS22534.1    LBMM01004265    KMQ92645.1    DS232844    EDS26077.1    PYGN01000508    PSN45175.1    KQ982796    KYQ50604.1    UFQS01000011    UFQT01000011    SSW97151.1    SSX17537.1    GECZ01003056    JAS66713.1    CVRI01000047    CRK97635.1    ABLF02011999    ABLF02012000    GAKP01017494    JAC41458.1    GAMC01017517    JAB89038.1    PNF32424.1    GGMS01012661    MBY81864.1    GBXI01004417    JAD09875.1    GECZ01031494    JAS38275.1    GDHF01031617    GDHF01015805    JAI20697.1    JAI36509.1    GDHC01016504    JAQ02125.1    GBHO01021334    GBHO01021331    JAG22270.1    JAG22273.1    GBBI01003164    JAC15548.1    GFTR01008532    JAW07894.1    GL732547    EFX80446.1    GDIQ01222280    GDIQ01143354    GDIQ01066196    JAK29445.1    GDIQ01109266    JAL42460.1    GDIQ01152856    GDIQ01112670    JAK98869.1    GDIP01103022    LRGB01001253    JAM00693.1    KZS13274.1    GDIP01014116    JAM89599.1    GDIP01232406    JAI90995.1    GECL01001634    JAP04490.1    GDIP01191522    JAJ31880.1    GDIQ01171648    JAK80077.1    GDIQ01036146    JAN58591.1    CH964291    EDW86426.2    GDIQ01208142    JAK43583.1    KQ977939    KYM98527.1    GGMS01002785    MBY71988.1    GDIP01114273    JAL89441.1    JXJN01015766    CH916376    EDV95301.1    CM000162    EDX02141.1    ACPB03000025    CH954180    EDV46696.1    GDIQ01049801    JAN44936.1    GDIP01043740    JAM59975.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000283053    UP000218220    UP000008237    + More
UP000053825    UP000076502    UP000078492    UP000279307    UP000053097    UP000078541    UP000007755    UP000053105    UP000005203    UP000242457    UP000008820    UP000075886    UP000215335    UP000002358    UP000075884    UP000069272    UP000075920    UP000076408    UP000027135    UP000069940    UP000249989    UP000075881    UP000075900    UP000007062    UP000075882    UP000075901    UP000000673    UP000075902    UP000075885    UP000076407    UP000075903    UP000000311    UP000075840    UP000030765    UP000235965    UP000075880    UP000075883    UP000078540    UP000036403    UP000002320    UP000245037    UP000075809    UP000183832    UP000007819    UP000095300    UP000000305    UP000076858    UP000091820    UP000007798    UP000078542    UP000092443    UP000078200    UP000079169    UP000092460    UP000001070    UP000002282    UP000015103    UP000008711   

PRIDE

H9IWE1   

Pfam

PF00270   DEAD        + More
PF07717   OB_NTP_bind
PF00271   Helicase_C
PF04408   HA2
PF04188   Mannosyl_trans2
PF03098   An_peroxidase
PF01399   PCI
PF18005   eIF3m_C_helix
PF08022   FAD_binding_8
PF01794   Ferric_reduct
PF08030   NAD_binding_6

Interpro

IPR027417   P-loop_NTPase        + More
IPR007502   Helicase-assoc_dom       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR011709   DUF1605       
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR042035   DEAH_win-hel_dom       
IPR002464   DNA/RNA_helicase_DEAH_CS       
IPR007315   PIG-V/Gpi18       
IPR019791   Haem_peroxidase_animal       
IPR037120   Haem_peroxidase_sf_animal       
IPR010255   Haem_peroxidase_sf       
IPR027528   eIF3m       
IPR000717   PCI_dom       
IPR040750   eIF3m_C_helix       
IPR018527   Rubredoxin_Fe_BS       
IPR011992   EF-hand-dom_pair       
IPR017938   Riboflavin_synthase-like_b-brl       
IPR002048   EF_hand_dom       
IPR013112   FAD-bd_8       
IPR017927   FAD-bd_FR_type       
IPR029595   DUOX1/Duox       
IPR013130   Fe3_Rdtase_TM_dom       
IPR018247   EF_Hand_1_Ca_BS       
IPR013121   Fe_red_NAD-bd_6       
IPR039261   FNR_nucleotide-bd       

SUPFAM

SSF52540   SSF52540        + More
SSF48113   SSF48113       
SSF47473   SSF47473       
SSF63380   SSF63380       
SSF52343   SSF52343       

Gene 3D

1.10.10.2130     1.10.640.10     3.40.50.80    

CDD

cd00079  HELICc
cd00051  EFh

ProteinModelPortal

H9IWE1   A0A194RIL9   A0A194QCI8   A0A437BVI8   A0A2A4JIC2   A0A2H1VVT9   + More
A0A2H1WG22   E2BBB5   A0A0L7RFZ6   E9IA45   A0A154P2V7   A0A195ED09   A0A3L8E3F6   A0A026W426   A0A151JX31   F4X447   A0A0N0BHN3   A0A087ZVP3   A0A2A3E913   A0A310SER1   Q16ZW5   A0A182Q8L6   A0A232ELE6   K7IZR6   A0A182NSC3   A0A182F869   A0A182VR46   A0A182YGA7   A0A067QZV6   A0A182H8U1   A0A182JQJ0   A0A182RXI4   A0A1S4GCB0   Q7PXC6   A0A182L8W0   A0A182T6X9   W5J946   A0A182U3Q7   A0A182PSG2   A0A182X9N5   A0A182VJV8   E2A8T0   A0A2C9GQI6   A0A084VS66   A0A2J7QV15   A0A182J6Q0   A0A2J7QV18   A0A182MDT4   A0A151HZP2   A0A1B6D6A9   A0A0J7NJI1   B0XEL6   A0A2P8YLP0   A0A151WRX8   A0A336LMF3   A0A1B6GWG1   A0A1J1IBQ6   J9K3B6   A0A034VIS3   W8AWC2   A0A2J7QV12   A0A2S2QVX1   A0A0A1XG36   A0A1B6EK33   A0A0K8U1W1   A0A146L351   A0A0A9XYB6   A0A023F2W4   A0A1I8NLN9   A0A224XAE4   E9GJF2   A0A0P5HVU0   A0A0P5QV34   A0A0P5MVP6   A0A0P5VEA8   A0A0P6CJ48   A0A0P4YE01   A0A0V0GAR2   A0A0P5B119   A0A1A9WXX5   A0A0P5LCN2   A0A0P6GGA5   B4NPI6   A0A0P5IYB9   A0A151IDH4   A0A1A9XAY2   A0A1A9UY04   A0A1S4ESB8   A0A2S2Q2J9   A0A0P5UEA8   A0A1B0BK13   B4JX25   B4PZI5   T1HSD3   B3NVN1   A0A0P6FCC7   A0A0P5ZKG5  

PDB

6QIC     E-value=9.50002e-27,     Score=301

KEGG

101744276    K20101 ATP-dependent RNA helicase DHX34 [EC:3.6.4.13] | (RefSeq) probable ATP-dependent RNA helicase

GO

GO:0003676   GO:0004386   GO:0005524   GO:0016787   GO:0016021   GO:0006506   GO:0004584   GO:0003723   GO:0000184   GO:0034459   GO:0006979   GO:0004601   GO:0020037   GO:0003743   GO:0001732   GO:0016282   GO:0033290   GO:0071541   GO:0046872   GO:0050665   GO:0016174   GO:0005509   GO:0000287   GO:0004749   GO:0009165   GO:0009156   GO:0044249   GO:0006428   GO:0000049   GO:0006508   GO:0016286  

PANTHER

PTHR11972:SF126  

Subcellular location

Cytoplasm  

Length:

684

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0566200000000001

Exp number, first 60 AAs:

0.00805

Total prob of N-in:

0.00415

outside

1  -  684

 

 

Pi

191.559602

Theta

141.287185

Tajima's D

1.016779

CLR

0.4569

CSRT

0.664766761661917

Interpretation

Uncertain