Gene

KWMTBOMO12651

Pre Gene Modal

BGIBMGA001571

Annotation

PREDICTED:_glutathione_S-transferase_epsilon_6_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr21(+):10278695-10282046      View in EpiBrowser

Full name

Glutathione S-transferase 1      

Alternative Name

GST class-theta

Location in the cell

Mitochondrial   Reliability : 1.05 Nuclear   Reliability : 1.747

CDS

ATGACTCCGATATTATACAAGACTGACGCCAGTCCGCCTGCTAGGGCTGTGATGATGATTGTTGATATATTGGGACTAAAAGTTGACGAGCAGGAACTGAATCCAATATTACGCCAACAAGACACACCGGAATTTAAAAAAAAAAATCCAATGAGAACTATTCCTATATTAGAGGAAGGAGATTTCTACCTCGCGGATAGTCACGCCATTATGTTGTACTTGATCGATAAATACGGTAAACCGGAACACGCTCATCTCTATCCGAGCGAGAAAAGGAAACGAGCTACAATAAATCAACGACTTTTCTTTGACTGCGGAGTGCTATTCCCTAGATTGAGGGCCGTTATGGCACCAACGTACGCAGGAAAATTAGCGGAATTGAATCGAAACATGATCAAGAACATCGAGGATGCTTATTCAATAATGGAATCCTATCTAACAGAGAATTTGTATCTAGCTGATGAAGTTGTCACTGTAGCGGACATAAGCGCAATAACGACTATTTCGTCTTTGAACGGCTTGTACCCGGTAGATGAGAAAAGATATCCAAAACTTAGCAAATGGATAAACAGAATGAACGATAAAGAATATTGTAGAAAGATCAACACTCCCGGAAGCGAGCTACATGTGGCCGGTTTGATAGCCTTAATGGACAATACTAAACACAATCAGCAATCAAAACTTTAG

Protein

MTPILYKTDASPPARAVMMIVDILGLKVDEQELNPILRQQDTPEFKKKNPMRTIPILEEGDFYLADSHAIMLYLIDKYGKPEHAHLYPSEKRKRATINQRLFFDCGVLFPRLRAVMAPTYAGKLAELNRNMIKNIEDAYSIMESYLTENLYLADEVVTVADISAITTISSLNGLYPVDEKRYPKLSKWINRMNDKEYCRKINTPGSELHVAGLIALMDNTKHNQQSKL

Catalytic Activity

glutathione + RX = a halide anion + an S-substituted glutathione + H(+)

Subunit

Homodimer.

Similarity

Belongs to the GST superfamily.
Belongs to the GST superfamily. Theta family.

Keywords

Transferase  

Feature

chain  Glutathione S-transferase 1

Uniprot

B0LKP5   A0A194QI58   A0A3G1ZLA7   A0A075X2V3   A0A2H1VVV0   A0A194RE93   + More
A0A1W6I4K8   A0A0K0XRU6   A0A1P8L0U3   A0A077D9Y8   A0A3S2P106   A0A212F3G0   A0A0N1PIE3   O77409   Q2ABX5   X5CYF6   A0A1C9EGF0   A0A1L8D6F5   A0A1C9EGF2   A0A075X3R3   H9IYE6   A0A3G1ZLA5   A0A2W1BZ02   A0A0K8TUF8   Q2I0J3   A0A0L7LI53   A0A2H1WX04   X5CHJ9   A0A2A4IXK8   A0A077DB43   A0A2A4IXQ2   A0A0K0XRK4   A0A077D6F2   A0A2H1WIN4   B0LB15   A0A3G1ZLA9   A0A212FES8   A0A2H1WDA0   A0FKH1   A0A2H1WDG8   A0A2A4JI76   A0A0K8TVL2   A0A3G1T1G1   A0FKH2   A0A3G1ZLA8   A0A3G1ZLC2   B0LB16   D2I930   X5CCB3   A0A3G1ZLC3   D0UH25   A0A075X8X2   A0A3G1ZLB1   A0A2H1WKL0   A0A0K8TV08   A0A1P8L0S2   V5QP65   V5GSL4   A0A2H1WD57   A0A3G1ZLB5   A0A3G1ZLB4   A0A0D3M5V9   A0A3G1ZLB6   B0L4I1   X5D048   Q1EGY7   A0A075X244   A0A075X250   A0A0D3M5T7   A0A3G1ZLA6   A0A3B0ERN2   A0A2H1WPK9   A0A0K8TVK6   A0A3G1ZLB8   P46430   A0A1W6I4K6   A0A2H1WK31   A0A3G1ZLC0   A0A0K0XRM5   B4LNI6   A0A1P8PEV6   V5I823   A0A075X2I7   A0A3S2LLI2   A0A2R4FXF5   A0A1P8PEV4   A0A3G1RJ81   A0A1L8EHK4   A0A1L8EHS3   B4P4F3   A0A182PZ41   A0A1I8Q311   A0A2H1WKF1   A0A0L0CBD3   B4LCA0   A0A075X2W2   B4J5T2   A0A0A1WUT1   B4KM88   A0A0M4RGU3  

EC Number

2.5.1.18

Pubmed

26354079    30319435    26198868    22118469    9755475    19121390    + More
28756777    26017144    26227816    23803169    19715699    17966126    7742833    17994087    27742358    29912411    17550304    26108605    25830018   

EMBL

EU216543    ABY66600.1    KQ459193    KPJ03136.1    MH177584    AYM01156.1    + More
KF482956    AIH07580.1    ODYU01004750    SOQ44959.1    KQ460325    KPJ15789.1    KX500034    ARM39004.1    KP938861    AKS40342.1    KX229709    APW77570.1    KM099181    AIL29311.1    RSAL01000006    RVE54273.1    AGBW02010569    OWR48264.1    LADI01008471    KPJ20693.1    U66342    AAC35245.1    AB232916    GEYN01000102    BAE80117.1    JAV02027.1    KF929204    AHW45902.1    KX778609    AON96571.1    GEYN01000101    JAV02028.1    AON96572.1    KF482958    AIH07582.1    BABH01020533    MH177586    AYM01158.1    KZ149938    PZC77013.1    GCVX01000118    JAI18112.1    DQ355376    ABC79692.1    JTDY01000981    KOB75213.1    ODYU01011645    SOQ57522.1    KF929203    AHW45901.1    NWSH01004968    PCG64545.1    KM099182    AIL29312.1    NWSH01005772    PCG63962.1    KP938863    AKS40344.2    KM099183    AIL29313.1    ODYU01008927    SOQ52931.1    EF506488    ABS56976.1    MH177583    AYM01155.1    AGBW02008896    OWR52256.1    ODYU01007862    SOQ51007.1    EF026111    ABK20174.1    SOQ51006.1    NWSH01001309    PCG71767.1    GCVX01000120    JAI18110.1    MG992377    AXY94815.1    EF026112    ABK20175.1    MH177581    AYM01153.1    MH177596    AYM01168.1    EF506489    AB738325    ABS56977.1    BAM76808.1    GQ131803    ACZ73898.1    KF929207    AHW45905.1    MH177594    AYM01166.1    GQ856239    ACX85225.1    KF482957    AIH07581.1    MH177582    AYM01154.1    ODYU01009190    SOQ53442.1    GCVX01000107    JAI18123.1    KX229711    APW77572.1    KF595078    AHB18378.1    GALX01003869    JAB64597.1    SOQ51008.1    MH177592    AYM01164.1    MH177580    AYM01152.1    KJ468613    AIB07714.1    MH177589    AYM01161.1    EF370472    ABQ53630.1    KF929205    AHW45903.1    AY506545    AAS79891.1    KF482959    AIH07583.1    KF482964    AIH07588.1    KJ468614    AIB07715.1    MH177585    AYM01157.1    RBVL01000267    RKO09898.1    ODYU01010121    SOQ55005.1    GCVX01000125    JAI18105.1    MH177587    AYM01159.1    L32091    KX500033    ARM39003.1    SOQ53443.1    MH177588    AYM01160.1    KP938862    AKS40343.1    CH940648    EDW62166.1    KU522318    APX61037.1    GALX01005435    JAB63031.1    KF482960    AIH07584.1    RSAL01000067    RVE49301.1    MF034820    AVT42186.1    KU522319    APX61038.1    MG879008    AWX68888.1    GFDG01000651    JAV18148.1    GFDG01000650    JAV18149.1    CM000158    EDW91639.1    ODYU01009192    SOQ53446.1    JRES01000655    KNC29542.1    CH940647    EDW68745.1    KF482966    AIH07590.1    CH916367    EDW01858.1    GBXI01011665    JAD02627.1    CH933808    EDW08752.1    KR107238    ALF04573.1   

Proteomes

UP000053268    UP000053240    UP000283053    UP000007151    UP000005204    UP000037510    + More
UP000218220    UP000276569    UP000008792    UP000002282    UP000075885    UP000095300    UP000037069    UP000001070    UP000009192   

PRIDE

B0LKP5    H9IYE6    Q2I0J3    B0LB15    B0LB16   

Pfam

PF13417   GST_N_3        + More
PF00043   GST_C
PF14572   Pribosyl_synth
PF13793   Pribosyltran_N
PF02798   GST_N
PF14497   GST_C_3

Interpro

IPR036282   Glutathione-S-Trfase_C_sf        + More
IPR036249   Thioredoxin-like_sf       
IPR004045   Glutathione_S-Trfase_N       
IPR040079   Glutathione_S-Trfase       
IPR010987   Glutathione-S-Trfase_C-like       
IPR004046   GST_C       
IPR000836   PRibTrfase_dom       
IPR029057   PRTase-like       
IPR005946   Rib-P_diPkinase       
IPR000842   PRib_PP_synth_CS       
IPR029099   Pribosyltran_N       

SUPFAM

SSF52833   SSF52833        + More
SSF47616   SSF47616       
SSF53271   SSF53271       

CDD

cd06223  PRTases_typeI

ProteinModelPortal

B0LKP5   A0A194QI58   A0A3G1ZLA7   A0A075X2V3   A0A2H1VVV0   A0A194RE93   + More
A0A1W6I4K8   A0A0K0XRU6   A0A1P8L0U3   A0A077D9Y8   A0A3S2P106   A0A212F3G0   A0A0N1PIE3   O77409   Q2ABX5   X5CYF6   A0A1C9EGF0   A0A1L8D6F5   A0A1C9EGF2   A0A075X3R3   H9IYE6   A0A3G1ZLA5   A0A2W1BZ02   A0A0K8TUF8   Q2I0J3   A0A0L7LI53   A0A2H1WX04   X5CHJ9   A0A2A4IXK8   A0A077DB43   A0A2A4IXQ2   A0A0K0XRK4   A0A077D6F2   A0A2H1WIN4   B0LB15   A0A3G1ZLA9   A0A212FES8   A0A2H1WDA0   A0FKH1   A0A2H1WDG8   A0A2A4JI76   A0A0K8TVL2   A0A3G1T1G1   A0FKH2   A0A3G1ZLA8   A0A3G1ZLC2   B0LB16   D2I930   X5CCB3   A0A3G1ZLC3   D0UH25   A0A075X8X2   A0A3G1ZLB1   A0A2H1WKL0   A0A0K8TV08   A0A1P8L0S2   V5QP65   V5GSL4   A0A2H1WD57   A0A3G1ZLB5   A0A3G1ZLB4   A0A0D3M5V9   A0A3G1ZLB6   B0L4I1   X5D048   Q1EGY7   A0A075X244   A0A075X250   A0A0D3M5T7   A0A3G1ZLA6   A0A3B0ERN2   A0A2H1WPK9   A0A0K8TVK6   A0A3G1ZLB8   P46430   A0A1W6I4K6   A0A2H1WK31   A0A3G1ZLC0   A0A0K0XRM5   B4LNI6   A0A1P8PEV6   V5I823   A0A075X2I7   A0A3S2LLI2   A0A2R4FXF5   A0A1P8PEV4   A0A3G1RJ81   A0A1L8EHK4   A0A1L8EHS3   B4P4F3   A0A182PZ41   A0A1I8Q311   A0A2H1WKF1   A0A0L0CBD3   B4LCA0   A0A075X2W2   B4J5T2   A0A0A1WUT1   B4KM88   A0A0M4RGU3  

PDB

3VWX     E-value=2.33087e-36,     Score=378

KEGG

100141445    K00799 glutathione S-transferase [EC:2.5.1.18] | (RefSeq) GSTe6, GST12; glutathione S-transferase ep

PATHWAY

00480    Glutathione metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016740   GO:0004364   GO:0009156   GO:0009116   GO:0009165   GO:0016301   GO:0000287   GO:0004749   GO:0016021   GO:0006749   GO:0005515   GO:0044249   GO:0006428   GO:0000049   GO:0006508   GO:0016286  

PANTHER

PTHR10210  

Length:

228

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.12229

Exp number, first 60 AAs:

0.00145

Total prob of N-in:

0.09617

outside

1  -  228

 

 

Pi

258.925751

Theta

216.406923

Tajima's D

-1.014224

CLR

0.19139

CSRT

0.134093295335233

Interpretation

Uncertain