Gene

KWMTBOMO12632

Pre Gene Modal

BGIBMGA001560

Annotation

PREDICTED:_ras_GTPase-activating_protein_1_[Bombyx_mori]

Location

Bomo_Chr21(+):9726594-9740736      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.251

CDS

ATGGCTGATTTAATTCGAGCTATGGGGGCGCCCATAGGACCCCCTGTAAAGGACAAATTAGGATCTCCATCCACTGAATCAGAAGACGGGGGTGGTGACATTGCCGAATTGGCAGCTGAATTAGAGTTAGACGAAGCAGACGGACCAAGCACTAATGGTGAGCGTCAAGCCGTGCTGGCCCCGCCGGAGACTGAATGGTACCACGGCCGTCTAGACAGGTATACATCTGAGGAGCGTCTGTGGGCTGCCAGCAAACAAGGAAGCTACTTGGTGCGTGAGAGTGATCGTAAACCAGGATCATATGTTCTGAGTTATTTAGGACGCACAGGAATTAATCACTTCAGGATAACAGCGGTGTGTGGAGATTACTACATTGGAGGTCGACAGTTTGATTCTTTAACTGAACTTGTGGGCTTCTACAGTCACTGTTCTGACTTATTGAAAAGAGAACGACTGGTAGAGCCAGTACCACCACCAGAACCAGTGAACGATAAGAAGAGGGTTGTTGCAATTTTACCTTATACAAAAATGCCCGACACTGATGAATTGACTTTTCAAAAGGGCGACATCTTTTTTGTACATAATGACATGGGTGATGGATGGCTCTGGGTCACAGCTCATAGGACCGGTGAACAGGGAATGATATTTAGAGAGTTGGTTGAAGATCTGGATCCTTCTATCGATCCAAACACGGTATTTTCGTGGTTCCATCCAAACTGTACCAAGAGTGAAGCAGTTGACATGCTAGTCAAGGCGGGCCCTGGAAGTTTCCTCGTCAGACCATCTGATAATTCTCCAGGAGACTATTCTTTGTTCTTTCACATTAACAACCAGATTCAAAGGTTCAGGATTGAGAAGAAGGGCGTCAGGTACTTGATGGGAGGTCGAACCTTTGAGTGCTTGGATGCTGTGATCAATAGATATAGGAAAGAACAAATTGTTGAAGGACACACTTTAGGTCAGCCGCTTATTGCGGAAGGTCACACTATCGAGCCGCAGCAAAGTACAACAGGGGCTGCAGCTGAAAAGATATATGCAACATTACGCGAATGTCGAGATCAGATCGGTCTGAAAAAGACGAAAGGAATCAAGCACTATGGGTATCTGAACAAGAAATCTGACAAGGGTGCTAAAAAATGGAAGCCTTTATACTGTGTGCTATTACAGGAAGGAACCGACACACATTTGTATTTTTACGATTCGCCGAAAAGGACCAAACCAAAAGGACTCATCGATCTATCATGCGCATATCTTTACCAGGTTCACGAATCACTTTGGGAAAAGGAGTTTTGTTTCCAACTCGTCGAACGTGCCCTACCATGTCTCTCTACACATACATTCTTGGCTGCCAATACTGCTACTGAGGAGAGGGCCTGGATTGAGGCTCTAAGACCTTTATGTGTGCCGCAGCAAGCACGACACCAGTGCAAGGTGGGGCGCGTGTCGTGGGTGCGTTGGCTGCGCGTGCGTTGCCTGACGGCGCACCGGCTGCCCGCCCGCCTGGCGCCGCGCCCGCACCTGCGCGTGCTGCTGGGCGCCGCGCCCGTCGCCCGCACCCGCCCGCGCCCCTCGCCCGATCCGCACTGGGACGACGAGTTCTTCTTCGATGATATGCCTCCAGATGTAACTTCATTTACAATTACCGTACATAATACAGGGAAAAGAGGAAAAGAATCTGAAGTGGCTGAACTGACTATAGAACTCGCAAATTTGGCAAACGGTGAAGAAATAGAAGAATGGTATCCCTTAGTAGGAATGACTCCTATTGGGGAGTGGGGATCCTTGAGACTGCGGATAAGGTATATGCAAGAATTAGTAATGCCTCGTGAAGAGTACAACCCGCTTCGTCAATTGTTGCTGGAACCGGGCATTCCGGCTGTGAAGGCGTTAGCAGATCTTTGCAGGACCGATCGACAACCTTTGGCAACATCGGTGCTGAACACGTTCGCGGAGTGCGGGCGCGGCGCGGAGCTGGCCCGCGAGCTCACGTGCGCGGAGGTGGCGCGCGAGGGCGACCACAAGACGCTGTTCCGCGGCGCCTCGCTCGCCACCGCCGTGCTCGACGAGTTCATGCGCGCCCACTGCAAGCCCTTCCTACAGGCGGCGATTTCGGAAACCATTCAAAAGCTGATTGATTCTAAACAGACAGCAGAATTGAATCCCACTAAGATGGATTCACCTGACGACGCGTGTAACAATGCTGAATTTTTACTTATGATTCTCGATCAGATTACCCTATCAATATTTACTTCACCGGAAGCATGCCCTAAGCCGGTGAGATATCTGTGCGGGTGTCTGCAGCGAGCCGCGGTCGCCAAGTGGCCCAACGAACGCTTTGTACGCACCAGGGTCGTCTCAGGGTTCATATTCCTGCGGCTGATCTGTCCGGCGCTGGTGGAGCCGCGAGCGTGGACGCTGGTGCAGCGGGCGCCGCCCCCGCACGCGCAGCGCTCGCTGCTCATGGTCGCCAAGTGTCTGCAGAACCTCGCCAACCTCGTCGAGTTCGGAGCCAAGGAACCTTACATGGAAGTAGTGAATCCGTTCATCTTAAAGAACAAAGAGAGGATGGTCGTCTTCCTAGATCAACTGAGTAACGTGCCAGATCCTGGAAATTCGCCGCCCAATTCTAATGTCAATTTTGAAATCGCAAAAGAGCTAGCGACTCTCCATCATATTTGTGTGGCGCATTTGACTGAGCTTCAAGGATTGGCTAAGAACCAACCGGCGATACGTAAACTTGTCACCGTGACCGAGATGCTCACTAAACATAAGCAAAAATATCTAGAGATGATCAGATAA

Protein

MADLIRAMGAPIGPPVKDKLGSPSTESEDGGGDIAELAAELELDEADGPSTNGERQAVLAPPETEWYHGRLDRYTSEERLWAASKQGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYYIGGRQFDSLTELVGFYSHCSDLLKRERLVEPVPPPEPVNDKKRVVAILPYTKMPDTDELTFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVEDLDPSIDPNTVFSWFHPNCTKSEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHTLGQPLIAEGHTIEPQQSTTGAAAEKIYATLRECRDQIGLKKTKGIKHYGYLNKKSDKGAKKWKPLYCVLLQEGTDTHLYFYDSPKRTKPKGLIDLSCAYLYQVHESLWEKEFCFQLVERALPCLSTHTFLAANTATEERAWIEALRPLCVPQQARHQCKVGRVSWVRWLRVRCLTAHRLPARLAPRPHLRVLLGAAPVARTRPRPSPDPHWDDEFFFDDMPPDVTSFTITVHNTGKRGKESEVAELTIELANLANGEEIEEWYPLVGMTPIGEWGSLRLRIRYMQELVMPREEYNPLRQLLLEPGIPAVKALADLCRTDRQPLATSVLNTFAECGRGAELARELTCAEVAREGDHKTLFRGASLATAVLDEFMRAHCKPFLQAAISETIQKLIDSKQTAELNPTKMDSPDDACNNAEFLLMILDQITLSIFTSPEACPKPVRYLCGCLQRAAVAKWPNERFVRTRVVSGFIFLRLICPALVEPRAWTLVQRAPPPHAQRSLLMVAKCLQNLANLVEFGAKEPYMEVVNPFILKNKERMVVFLDQLSNVPDPGNSPPNSNVNFEIAKELATLHHICVAHLTELQGLAKNQPAIRKLVTVTEMLTKHKQKYLEMIR

Uniprot

H9IWC9   A0A194Q2Z2   A0A2H1VH02   A0A2A4JL14   A0A3S2LUW3   A0A212ESZ5   + More
A0A1Y1MPT5   A0A1W4XQB0   Q17P86   A0A084VRI2   A0A182NR45   A0A182J5D4   A0A182R0J3   A0A182FQY1   A0A2M4AAP4   A0A182MWC7   W5JG12   D6X3K0   A0A182RT13   A0A182K4P8   A0A182XAC3   A0A182VDX1   A0A182LE25   A0A182PCK5   A0A1I8JTM2   Q7QCN5   A0A182VZT1   A0A1B0FDR5   A0A1Q3F559   B0W6Q2   T1PEB8   A0A1I8M310   A0A1B0A263   A0A026VVT8   F4X8P6   A0A1A9VSA2   A0A195DRE3   A0A195FDE9   A0A3B0JWH3   A0A1I8PZ49   A0A158NBH5   A0A1A9WSY8   A0A1I8M309   U4UV51   A0A1B0BFW3   A0A1I8PZ37   A0A151IGX6   A0A1A9X701   U5EW97   A0A1I8PYZ7   B4HBS4   A0A034VMS3   A0A0K8W7W9   B4MA59   A0A0K8VBD4   A0A034VM24   A0A0L7QL00   B3MPU9   A0A2A3ESS7   A0A088AUZ6   B4L6Y7   A0A0N0BD73   A0A2J7PHS7   T1HM83   B4JX41   A0A1B6D7R6   A0A067RS08   B3NXF8   Q8IR23   B4PXB0   A0A0C9RBS9   A0A069DXG6   B4MT91   A0A1W4V3Z9   A0A0Q9X0G6   A0A0Q9WPT8   A0A0A1XKJ0   A0A0A1WZU5   B4IMH0   A0A023F5P7   W8AYH6   W8B9U1   A0A2J7PHT9   A0A195B9N7   A0A224XEB0   A0A182Y3Z2   A0A0A9XQH9   A0A224XHR7   E2A1F6   A0A1J1I8W5   E0VJF3   J9JNN1   A0A154PJM9   A0A1J1I8T6   A0A2H8TKU7   A0A0P6J634   A0A0P5KQF9   A0A0P5HQH6   A0A0P5MV02   A0A0P6HU81  

Pubmed

19121390    26354079    22118469    28004739    17510324    24438588    + More
20920257    23761445    18362917    19820115    20966253    12364791    14747013    17210077    25315136    24508170    21719571    21347285    23537049    17994087    25348373    18057021    24845553    10022880    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    26334808    25830018    25474469    24495485    25244985    25401762    26823975    20798317    20566863   

EMBL

BABH01006379    KQ459564    KPI99708.1    ODYU01002523    SOQ40123.1    NWSH01001071    + More
PCG72775.1    RSAL01000006    RVE54285.1    AGBW02012716    OWR44571.1    GEZM01024959    GEZM01024957    JAV87672.1    CH477193    EAT48547.1    ATLV01015679    KE525027    KFB40576.1    AXCN02001477    GGFK01004526    MBW37847.1    AXCM01000347    ADMH02001265    ETN63312.1    KQ971375    EEZ97639.1    APCN01000245    AAAB01008859    EAA08188.3    CCAG010010841    CCAG010010842    GFDL01012350    JAV22695.1    DS231849    EDS36883.1    KA646293    AFP60922.1    KK107786    EZA47780.1    GL888932    EGI57315.1    KQ980581    KYN15411.1    KQ981673    KYN38232.1    OUUW01000011    SPP86437.1    ADTU01011109    ADTU01011110    KB632379    ERL94111.1    JXJN01013675    KQ977661    KYN00689.1    GANO01003049    JAB56822.1    CH479264    EDW39496.1    GAKP01016109    JAC42843.1    GDHF01029613    GDHF01023589    GDHF01023185    GDHF01014764    GDHF01010925    GDHF01006387    GDHF01005349    JAI22701.1    JAI28725.1    JAI29129.1    JAI37550.1    JAI41389.1    JAI45927.1    JAI46965.1    CH940655    EDW66118.1    GDHF01016479    JAI35835.1    GAKP01016107    JAC42845.1    KQ414934    KOC59297.1    CH902621    EDV44711.2    KPU81701.1    KPU81702.1    KPU81703.1    KZ288192    PBC34189.1    CH933812    EDW06133.1    KQ435883    KOX69748.1    NEVH01025133    PNF15890.1    ACPB03015269    CH916376    EDV95317.1    GEDC01015569    JAS21729.1    KK852460    KDR23495.1    CH954180    EDV46917.1    AE014298    BT044449    AJ012609    AAF48558.2    AAN09380.1    AAN09381.2    AAS65383.1    ACH92514.1    AHN59784.1    AHN59785.1    CAA10073.1    CM000162    EDX01873.1    KRK06405.1    KRK06406.1    GBYB01014024    JAG83791.1    GBGD01000368    JAC88521.1    CH963851    EDW75330.1    KRF98226.1    KRF98227.1    GBXI01003219    JAD11073.1    GBXI01010384    JAD03908.1    CH480996    EDW46315.1    GBBI01002220    JAC16492.1    GAMC01016627    JAB89928.1    GAMC01016629    GAMC01016628    GAMC01016626    JAB89926.1    PNF15888.1    KQ976540    KYM81243.1    GFTR01008298    JAW08128.1    GBHO01021405    GDHC01019291    JAG22199.1    JAP99337.1    GFTR01008304    JAW08122.1    GL435766    EFN72629.1    CVRI01000044    CRK96704.1    AAZO01002829    DS235222    EEB13509.1    ABLF02031355    KQ434926    KZC11694.1    CRK96703.1    GFXV01002962    MBW14767.1    GDIQ01012598    JAN82139.1    GDIQ01187943    GDIQ01175195    GDIQ01075232    LRGB01000024    JAK63782.1    KZS21760.1    GDIQ01229781    JAK21944.1    GDIQ01151461    JAL00265.1    GDIQ01038759    JAN55978.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000283053    UP000007151    UP000192223    + More
UP000008820    UP000030765    UP000075884    UP000075880    UP000075886    UP000069272    UP000075883    UP000000673    UP000007266    UP000075900    UP000075881    UP000076407    UP000075903    UP000075882    UP000075885    UP000075840    UP000007062    UP000075920    UP000092444    UP000002320    UP000095301    UP000092445    UP000053097    UP000007755    UP000078200    UP000078492    UP000078541    UP000268350    UP000095300    UP000005205    UP000091820    UP000030742    UP000092460    UP000078542    UP000092443    UP000008744    UP000008792    UP000053825    UP000007801    UP000242457    UP000005203    UP000009192    UP000053105    UP000235965    UP000015103    UP000001070    UP000027135    UP000008711    UP000000803    UP000002282    UP000007798    UP000192221    UP000001292    UP000078540    UP000076408    UP000000311    UP000183832    UP000009046    UP000007819    UP000076502    UP000076858   

PRIDE

H9IWC9    Q8IR23   

Pfam

PF00018   SH3_1        + More
PF00168   C2
PF00017   SH2
PF00169   PH
PF00616   RasGAP
PF13873   Myb_DNA-bind_5
PF07525   SOCS_box
PF12796   Ank_2

Interpro

IPR000980   SH2        + More
IPR001452   SH3_domain       
IPR036860   SH2_dom_sf       
IPR008936   Rho_GTPase_activation_prot       
IPR035652   RasGAP_SH3       
IPR035892   C2_domain_sf       
IPR035842   RasGAP_C_SH2       
IPR011993   PH-like_dom_sf       
IPR001849   PH_domain       
IPR000008   C2_dom       
IPR028554   p120-RasGAP       
IPR036028   SH3-like_dom_sf       
IPR001936   RasGAP_dom       
IPR039360   Ras_GTPase       
IPR023152   RasGAP_CS       
IPR035841   RasGAP_N_SH2       
IPR028002   Myb_DNA-bind_5       
IPR036770   Ankyrin_rpt-contain_sf       
IPR001496   SOCS_box       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       

SUPFAM

SSF55550   SSF55550        + More
SSF50044   SSF50044       
SSF48350   SSF48350       
SSF48403   SSF48403       

Gene 3D

2.30.29.30     2.60.40.150     3.30.505.10     1.25.40.20    

CDD

cd11788  SH3_RasGAP
cd10354  SH2_Cterm_RasGAP
cd10353  SH2_Nterm_RasGAP
cd00204  ANK

ProteinModelPortal

H9IWC9   A0A194Q2Z2   A0A2H1VH02   A0A2A4JL14   A0A3S2LUW3   A0A212ESZ5   + More
A0A1Y1MPT5   A0A1W4XQB0   Q17P86   A0A084VRI2   A0A182NR45   A0A182J5D4   A0A182R0J3   A0A182FQY1   A0A2M4AAP4   A0A182MWC7   W5JG12   D6X3K0   A0A182RT13   A0A182K4P8   A0A182XAC3   A0A182VDX1   A0A182LE25   A0A182PCK5   A0A1I8JTM2   Q7QCN5   A0A182VZT1   A0A1B0FDR5   A0A1Q3F559   B0W6Q2   T1PEB8   A0A1I8M310   A0A1B0A263   A0A026VVT8   F4X8P6   A0A1A9VSA2   A0A195DRE3   A0A195FDE9   A0A3B0JWH3   A0A1I8PZ49   A0A158NBH5   A0A1A9WSY8   A0A1I8M309   U4UV51   A0A1B0BFW3   A0A1I8PZ37   A0A151IGX6   A0A1A9X701   U5EW97   A0A1I8PYZ7   B4HBS4   A0A034VMS3   A0A0K8W7W9   B4MA59   A0A0K8VBD4   A0A034VM24   A0A0L7QL00   B3MPU9   A0A2A3ESS7   A0A088AUZ6   B4L6Y7   A0A0N0BD73   A0A2J7PHS7   T1HM83   B4JX41   A0A1B6D7R6   A0A067RS08   B3NXF8   Q8IR23   B4PXB0   A0A0C9RBS9   A0A069DXG6   B4MT91   A0A1W4V3Z9   A0A0Q9X0G6   A0A0Q9WPT8   A0A0A1XKJ0   A0A0A1WZU5   B4IMH0   A0A023F5P7   W8AYH6   W8B9U1   A0A2J7PHT9   A0A195B9N7   A0A224XEB0   A0A182Y3Z2   A0A0A9XQH9   A0A224XHR7   E2A1F6   A0A1J1I8W5   E0VJF3   J9JNN1   A0A154PJM9   A0A1J1I8T6   A0A2H8TKU7   A0A0P6J634   A0A0P5KQF9   A0A0P5HQH6   A0A0P5MV02   A0A0P6HU81  

PDB

1WQ1     E-value=1.14736e-74,     Score=716

KEGG

101743695    K04352 Ras GTPase-activating protein 1 | (RefSeq) ras GTPase-activating protein 1

PATHWAY

04013    MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0007165   GO:0005096   GO:0046580   GO:0016021   GO:0120177   GO:0005104   GO:0001784   GO:0048149   GO:0005122   GO:0030100   GO:0016319   GO:0005829   GO:0040037   GO:0043087   GO:0005515   GO:0006418   GO:0004822   GO:0005737   GO:0006428   GO:0000049   GO:0006508   GO:0016286  

PANTHER

PTHR10194:SF19   PTHR10194  

Length:

932

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01574

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00013

outside

1  -  932

 

 

Pi

160.151864

Theta

165.356945

Tajima's D

-0.851816

CLR

0.104983

CSRT

0.168241587920604

Interpretation

Uncertain