Gene

KWMTBOMO12626  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001417

Annotation

PREDICTED:_protein_ariadne-1_[Papilio_polytes]

Location

Bomo_Chr21(-):9585855-9596193      View in EpiBrowser

Full name

RBR-type E3 ubiquitin transferase      

Location in the cell

Nuclear   Reliability : 3.697

CDS

ATGGATTCGGAAGATGACACGAAAGACGATGTGGACTCGGGTAATGAGTCTAGTGGAGACGATGTCGACTTTGCAATGGACGTTGAAACTCATAGTACAAGGGAAAGACAAACTGAGCTTGAGGAGTATCCTTACGAGGTTTTGTCTACAGAGGAGATTGTCCAACATATGGTTGACTGCATTAAAGAAGTGAACACTGTCGTCGAGATTCCAGCAACAACAACAAGGATCTTACTGAATCATTTCAAATGGGACAAAGAGAAGCTTATGGAACGTTTTTATGATGGAGACCAGGATCAGTTGTTCTCTGAAGCTAGAGTTATCAATCCATTCAGGAAACCTGTCATACAAAGGCCAAAGCTTCCCAGGAGGATATCAACGTCTGGTATGGAAGAATGTGAAATATGTTTCTCAGTTTTACCAACCTCTATTATGACTGGGTTGGAATGTGGTCACAGATTTTGCACGCAATGCTGGTGTGAATATTTAACTACGAAAATAATGGAAGAAGGCTTAGGTCAAACAATAGCTTGTGCCGCTCACGCCTGCGACATACTTGTTGACGATGCGACCGTGATGCGGCTAGTACGAGACTCTCGTGTTAAACTTAAATATCAACACATTATAACGAATAGTTTTGTGGAGTGCAACCGGCTGCTGCGCTGGTGCCCGTCCCCGGACTGCAGCAACGCGATCAAGGTGGCGTACGTGGAGGCGGCGCCGGTGACGTGCCGCTGCGGACACACGTTCTGCTTCGCCTGCGGAGAGAACTGGCACGATCCGGTCCGGTGCTGTTTACTGAGGAAGTGGATTAAGAAATGCGACGACGATTCGGAGACCTCAAATTGGATAGCGGCTAACACGAAGGAGTGTCCTAAATGCAACGTCACCATCGAGAAGGACGGCGGCTGCAACCACATGGTGTGCAAGAATCAGAATTGCAAGGCCGACTTCTGCTGGGTGTGTCTTGGACCTTGGGAGCCCCACGGCAGCAGCTGGTACAGCTGTAACAGATACGACGAGGACGAAGCGAAAGCAGCCCGGGACGCACAGGAGCGATCCCGCGCAGCGCTGCAGCGCTATCTGTTCTACTGCAACCGGTACATGAACCACATGCAGTCGCTGCGCTTCGAGTCCAAACTCTACGCCTCGGTTAAAGAGAAGATGGAGGAGATGCAGCAACACAACATGAGCTGGATTGAGGTCCAATTCCTCAAGAAAGCTGTAGATATTCTCTGCCAGTGCCGACAAACGCTGATGTACACGTACGTGTTCGCGTATTACTTGCGCAAGAACAACCAGTCGGTCATATTCGAGGACAACCAACGCGACTTGGAGTCGGCGACCGAAACGCTCTCGGAGTACTTGGAGCGGGACATCACTAGCGAGAACCTTGCCGACATCAAGCAGAAGGTTCAAGATAAATACAGATACTGTGACAGTCGGCGAAAAGTGTTATTAGAGCACGTGCACGAGGGATACGAGAAGGACTGCTGGGACTACACAGAGTAA

Protein

MDSEDDTKDDVDSGNESSGDDVDFAMDVETHSTRERQTELEEYPYEVLSTEEIVQHMVDCIKEVNTVVEIPATTTRILLNHFKWDKEKLMERFYDGDQDQLFSEARVINPFRKPVIQRPKLPRRISTSGMEECEICFSVLPTSIMTGLECGHRFCTQCWCEYLTTKIMEEGLGQTIACAAHACDILVDDATVMRLVRDSRVKLKYQHIITNSFVECNRLLRWCPSPDCSNAIKVAYVEAAPVTCRCGHTFCFACGENWHDPVRCCLLRKWIKKCDDDSETSNWIAANTKECPKCNVTIEKDGGCNHMVCKNQNCKADFCWVCLGPWEPHGSSWYSCNRYDEDEAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFESKLYASVKEKMEEMQQHNMSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLRKNNQSVIFEDNQRDLESATETLSEYLERDITSENLADIKQKVQDKYRYCDSRRKVLLEHVHEGYEKDCWDYTE

Catalytic Activity

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.

Similarity

Belongs to the RBR family.

Uniprot

H9IVY6   A0A3S2M918   A0A1E1WSH5   A0A2A4IZF6   A0A2A4IYG5   A0A1E1WJZ4   + More
A0A194Q4U2   A0A2H1W2P6   A0A2J7R235   A0A067R7Y9   A0A224XMJ8   A0A023F5R3   A0A154P8K3   A0A0A9Y272   A0A0A9Y7R7   E0VRP1   T1IE78   A0A0A9Y4Q0   A0A310S672   A0A0A9YC94   A0A026W6K1   A0A0L7R9J6   A0A195C946   A0A151IWR7   A0A151WNB4   A0A2A4IY32   A0A195F4U3   A0A0N1ITV0   A0A2A3E4P3   A0A087ZQL8   V9I9T5   U4UWY5   E2ABE9   A0A1B6GNI4   A0A0J7NI82   A0A1B6G3Q4   E2B3Z6   J9JWN6   A0A2S2N673   A0A1Y1JR29   A0A0C9QQC7   A0A1B6HFM2   D6W822   A0A158N8X3   N6UI12   A0A2S2R1D4   A0A2P8YEJ4   A0A1B6DWQ4   K7IWP7   A0A232F279   A0A1B6DH29   A0A1Y1KMK1   A0A1B6DUY1   A0A1W4WL44   A0A1B6EDI8   E9IIR4   F4W9J2   U5EVD4   A0A1B0CHX7   A0A1L8DSV2   A0A0P6J528   A0A023EW10   A0A1Q3FFT3   N6TYD7   U4ULC7   A0A182LYG2   B0WDR8   A0A182WFY4   A0A182NC73   A0A1S4H580   A0A182KVN3   A0A182I5G2   A0A182WYD3   A0A182QQU8   A0A182RW30   A0A182YKK6   A0A2R5L864   A0A182JF80   A0A0T6BHD1   A0A2M4BL69   A0A2M4AA06   W5JVA5   A0A182F475   A0A182PJC8   A0A1Z5L7W4   A0A3R7NVW6   A0A2M3Z5U3   A0A0P4WLC4   A0A1Y9IUF0   A0A1Y9HDH3   L7MAF4   A0A1E1XQA3   A0A023GMZ8   G3MKV1   A0A1E1XCE1   A0A0N8DC36   A0A131XI44   A0A131Y0D8   B7P5K4   A0A0P6FQW6  

EC Number

2.3.2.31

Pubmed

19121390    26354079    24845553    25474469    25401762    26823975    + More
20566863    24508170    30249741    23537049    20798317    28004739    18362917    19820115    21347285    29403074    20075255    28648823    21282665    21719571    26999592    24945155    12364791    20966253    25244985    20920257    23761445    28528879    25576852    29209593    22216098    28503490    28049606   

EMBL

BABH01006368    RSAL01000006    RVE54291.1    GDQN01009458    GDQN01001126    JAT81596.1    + More
JAT89928.1    NWSH01004601    PCG64866.1    PCG64865.1    GDQN01006980    GDQN01003730    JAT84074.1    JAT87324.1    KQ459585    KPI98425.1    ODYU01005827    SOQ47102.1    NEVH01008200    PNF34891.1    KK852643    KDR19556.1    GFTR01006766    JAW09660.1    GBBI01002197    JAC16515.1    KQ434844    KZC08183.1    GBHO01016482    GBRD01002612    JAG27122.1    JAG63209.1    GBHO01016481    GBRD01002611    GDHC01006969    JAG27123.1    JAG63210.1    JAQ11660.1    DS235478    EEB16047.1    ACPB03017568    GBHO01016480    GBRD01002610    JAG27124.1    JAG63211.1    KQ822452    OAD46915.1    GBHO01016479    GBRD01002609    GDHC01008448    JAG27125.1    JAG63212.1    JAQ10181.1    KK107372    QOIP01000004    EZA51742.1    RLU23234.1    KQ414624    KOC67542.1    KQ978068    KYM97389.1    KQ980849    KYN12223.1    KQ982907    KYQ49402.1    PCG64867.1    KQ981810    KYN35411.1    KQ435735    KOX77194.1    KZ288386    PBC26454.1    JR037590    JR037591    JR037592    AEY57858.1    AEY57859.1    AEY57860.1    KB632399    ERL94821.1    GL438237    EFN69270.1    GECZ01030188    GECZ01005763    GECZ01005292    JAS39581.1    JAS64006.1    JAS64477.1    LBMM01004640    KMQ92215.1    GECZ01028322    GECZ01012694    JAS41447.1    JAS57075.1    GL445428    EFN89583.1    ABLF02040829    GGMR01000028    MBY12647.1    GEZM01102975    GEZM01102974    JAV51654.1    GBYB01002837    GBYB01002839    JAG72604.1    JAG72606.1    GECU01034179    JAS73527.1    KQ971307    EFA11010.1    ADTU01008901    APGK01024787    APGK01024788    KB740562    ENN80276.1    GGMS01014377    MBY83580.1    PYGN01000659    PSN42682.1    GEDC01007196    JAS30102.1    NNAY01001253    OXU24609.1    GEDC01012299    JAS24999.1    GEZM01082016    JAV61440.1    GEDC01007802    JAS29496.1    GEDC01001331    JAS35967.1    GL763521    EFZ19528.1    GL888030    EGI69167.1    GANO01001081    JAB58790.1    AJWK01012844    AJWK01012845    AJWK01012846    AJWK01012847    GFDF01004555    JAV09529.1    GDUN01000710    JAN95209.1    GAPW01001079    JAC12519.1    GFDL01008637    JAV26408.1    APGK01050039    KB741165    ENN73396.1    KB632352    ERL93303.1    AXCM01007153    DS231900    EDS44821.1    AAAB01008823    APCN01003438    AXCN02001759    GGLE01001519    MBY05645.1    LJIG01000204    KRT86736.1    GGFJ01004603    MBW53744.1    GGFK01004127    MBW37448.1    ADMH02000248    ETN67248.1    GFJQ02003453    JAW03517.1    QCYY01002718    ROT68111.1    GGFM01003140    MBW23891.1    GDRN01039062    JAI67209.1    GACK01004911    JAA60123.1    GFAA01001942    JAU01493.1    GBBM01000895    JAC34523.1    JO842502    AEO34119.1    GFAC01002268    JAT96920.1    GDIQ01210403    GDIP01048359    LRGB01000024    JAK41322.1    JAM55356.1    KZS21710.1    GEFH01001778    JAP66803.1    GEFM01003844    JAP71952.1    ABJB010048594    ABJB010235798    ABJB010369897    ABJB010431572    ABJB010658312    ABJB010940894    ABJB011078547    DS641459    EEC01876.1    GDIQ01055565    JAN39172.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000235965    UP000027135    + More
UP000076502    UP000009046    UP000015103    UP000053097    UP000279307    UP000053825    UP000078542    UP000078492    UP000075809    UP000078541    UP000053105    UP000242457    UP000005203    UP000030742    UP000000311    UP000036403    UP000008237    UP000007819    UP000007266    UP000005205    UP000019118    UP000245037    UP000002358    UP000215335    UP000192223    UP000007755    UP000092461    UP000075883    UP000002320    UP000075920    UP000075884    UP000075882    UP000075840    UP000076407    UP000075886    UP000075900    UP000076408    UP000075880    UP000000673    UP000069272    UP000075885    UP000283509    UP000076858    UP000001555   

PRIDE

H9IVY6   

Pfam

PF01485   IBR        + More
PF16450   Prot_ATP_ID_OB
PF00004   AAA
PF17862   AAA_lid_3

Interpro

IPR001841   Znf_RING        + More
IPR031127   E3_UB_ligase_RBR       
IPR002867   IBR_dom       
IPR013083   Znf_RING/FYVE/PHD       
IPR031126   Ariadne-2       
IPR017907   Znf_RING_CS       
IPR005937   26S_Psome_P45-like       
IPR032501   Prot_ATP_ID_OB       
IPR035263   PSMC6       
IPR041569   AAA_lid_3       
IPR003593   AAA+_ATPase       
IPR027417   P-loop_NTPase       
IPR003960   ATPase_AAA_CS       
IPR003959   ATPase_AAA_core       

SUPFAM

SSF52540   SSF52540       

Gene 3D

3.30.40.10    

ProteinModelPortal

H9IVY6   A0A3S2M918   A0A1E1WSH5   A0A2A4IZF6   A0A2A4IYG5   A0A1E1WJZ4   + More
A0A194Q4U2   A0A2H1W2P6   A0A2J7R235   A0A067R7Y9   A0A224XMJ8   A0A023F5R3   A0A154P8K3   A0A0A9Y272   A0A0A9Y7R7   E0VRP1   T1IE78   A0A0A9Y4Q0   A0A310S672   A0A0A9YC94   A0A026W6K1   A0A0L7R9J6   A0A195C946   A0A151IWR7   A0A151WNB4   A0A2A4IY32   A0A195F4U3   A0A0N1ITV0   A0A2A3E4P3   A0A087ZQL8   V9I9T5   U4UWY5   E2ABE9   A0A1B6GNI4   A0A0J7NI82   A0A1B6G3Q4   E2B3Z6   J9JWN6   A0A2S2N673   A0A1Y1JR29   A0A0C9QQC7   A0A1B6HFM2   D6W822   A0A158N8X3   N6UI12   A0A2S2R1D4   A0A2P8YEJ4   A0A1B6DWQ4   K7IWP7   A0A232F279   A0A1B6DH29   A0A1Y1KMK1   A0A1B6DUY1   A0A1W4WL44   A0A1B6EDI8   E9IIR4   F4W9J2   U5EVD4   A0A1B0CHX7   A0A1L8DSV2   A0A0P6J528   A0A023EW10   A0A1Q3FFT3   N6TYD7   U4ULC7   A0A182LYG2   B0WDR8   A0A182WFY4   A0A182NC73   A0A1S4H580   A0A182KVN3   A0A182I5G2   A0A182WYD3   A0A182QQU8   A0A182RW30   A0A182YKK6   A0A2R5L864   A0A182JF80   A0A0T6BHD1   A0A2M4BL69   A0A2M4AA06   W5JVA5   A0A182F475   A0A182PJC8   A0A1Z5L7W4   A0A3R7NVW6   A0A2M3Z5U3   A0A0P4WLC4   A0A1Y9IUF0   A0A1Y9HDH3   L7MAF4   A0A1E1XQA3   A0A023GMZ8   G3MKV1   A0A1E1XCE1   A0A0N8DC36   A0A131XI44   A0A131Y0D8   B7P5K4   A0A0P6FQW6  

PDB

4KC9     E-value=0,     Score=1890

KEGG

101741924    K11968 ariadne-1 [EC:2.3.2.31] | (RefSeq) protein ariadne-1

GO

GO:0046872   GO:0004842   GO:0016740   GO:0016874   GO:0061630   GO:0032436   GO:0031624   GO:0000151   GO:0006511   GO:0000209   GO:0005737   GO:0005524   GO:0030163   GO:0036402   GO:0005515   GO:0008270   GO:0006814   GO:0005509   GO:0005216   GO:0006811   GO:0016020   GO:0004190   GO:0006508   GO:0016286  

PANTHER

PTHR11685   PTHR11685:SF230   PTHR23073:SF76  

Length:

503

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0055

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00589

outside

1  -  503

 

 

Pi

240.626378

Theta

178.7661

Tajima's D

0.553231

CLR

0.3275

CSRT

0.539523023848808

Interpretation

Uncertain