Gene

KWMTBOMO12621  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001556

Annotation

PREDICTED:_phosphomevalonate_kinase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr21(+):9493304-9495884      View in EpiBrowser

Full name

Phosphomevalonate kinase      

Location in the cell

Nuclear   Reliability : 2.531

CDS

ATGTCAAATAGCCTGTTCCTGTTGATTTTCGGGAAGATGTCTCCAAAAATTATCTTGTTATTCAGTGGTAAAAGGAAGTCTGGAAAAGACTTTTTGACTGATCATTTAAGACACATTTTAGCAGATAAGTGTGAAATAATTAAAATATCTCAACCTATCAAGACTCATTGGGCTAAAGAGAAAAATTTGAATTTGAACGAATTGCTCAGTGAGGGTGAATATAAGGAACAATACAGACTGGAGATGATAAAATGGAGTGAGGAAATGCGAAACAAAGATTATGGATGCTTTTGTAAAGCAGCTTGTGAAAATGCTGCCATTAAACCGGTGTGGATTGTAAGTGACATTAGACGTAAGACAGATATACGCTGGTTCAAGGAGACATATGGGGACATCATCCGAACAGTGAGAATAACTGCAGACGATCGAACTAGAAAGGAAAGAGGCTTTCAATTCCAGGTTGGAGTTGATGATGCCACTTCAGAATGTGATTTGGATGATTACAATGATTGGGATGTGGTGGTTAACAATGGAGAAGGAAGGGATTCTTTAGAAGAGCAGTTGGATAGCATATTAAAATTAGTGTCTAATTTATGA

Protein

MSNSLFLLIFGKMSPKIILLFSGKRKSGKDFLTDHLRHILADKCEIIKISQPIKTHWAKEKNLNLNELLSEGEYKEQYRLEMIKWSEEMRNKDYGCFCKAACENAAIKPVWIVSDIRRKTDIRWFKETYGDIIRTVRITADDRTRKERGFQFQVGVDDATSECDLDDYNDWDVVVNNGEGRDSLEEQLDSILKLVSNL

Catalytic Activity

(R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP

Uniprot

A5A7A1   Q2F663   A0A1E1W532   A0A194RE64   A0A194Q3V4   A0A2H4UZJ1   + More
A0A212FAT1   S4PSD3   A0A2H1VHT5   A0A437BV01   A0A0L7LT63   A0A1L8DCK1   A0A1L8DCB3   A0A0G3F8N7   I1VX03   A0A1Y1LHQ3   A0A2P8YEN0   A0A0M8ZUB2   A0A1Y1LLH5   A0A067QIK8   A0A151IAC4   A0A195F2S9   A0A1Q3F2N5   A0A088ACQ4   F4W991   A0A195B5P9   A0A182PG92   A0A158P0X9   A0A232FGD7   A0A0L7RHW4   A0A0J7KUY5   E2APH8   K7IV48   A0A195EDR7   A0A310SQ09   A0A0K8TKK7   A0A1W4X2P2   A0A151X926   A0A026WB33   J3JXH7   B4M914   A0A182H8J2   A0A182W575   A0A3B0JUY2   B4JPC9   B4KKI5   A0A182VJX8   A0A024BT05   I1VJ81   E9J757   A0A182SFX1   A0A182JZ84   A0A182LX45   A0A182XPI1   Q7PS33   A0A2R7VT85   A0A182HMX9   A0A151NDS3   B0X8P2   W8B3P5   H2ZXB1   E0VP13   B4GKQ7   Q16I28   E2BBC3   A0A0C9RL29   A0A0H4IRI1   A0A1I8N215   A0A1B6M1B1   B3ML74   H0V6W2   A0A0A1WJS5   A0A182QJB3   Q29PG7   A0A0P4VLC4   L5JWF0   Q1HRB3   A0A2A3EI14   A0A182JMP7   T1HQ88   A0A3Q7N464   A0A1U7SYX1   M3VWG9   A0A182N0T1   C4WSJ1   F6V984   X1WUX6   G1RL78   A0A3L8RV14   B5G1H5   V3Z9K9   A0A2Y9EUI6   A0A2Y9E8Q2   A0A0A9YL53   B5G1H6   D0G7E0   A0A341BMM0   A0A2U4A2V2   A0A2Y9LZU6  

EC Number

2.7.4.2

Pubmed

17628279    19121390    26354079    29185447    22118469    23622113    + More
26227816    28004739    29403074    24845553    21719571    21347285    28648823    20798317    20075255    26369729    24508170    30249741    22516182    23537049    17994087    26483478    21282665    12364791    14747013    17210077    22293439    24495485    9215903    20566863    17510324    26899871    25315136    21993624    25830018    15632085    27129103    23258410    17204158    17975172    19892987    30282656    17018643    23254933    25401762   

EMBL

BABH01006364    AB274992    BAF62110.1    DQ311209    ABD36154.1    GDQN01010835    + More
GDQN01009164    GDQN01009005    GDQN01004336    JAT80219.1    JAT81890.1    JAT82049.1    JAT86718.1    KQ460325    KPJ15759.1    KQ459564    KPI99689.1    KY971769    AUA18036.1    AGBW02009427    OWR50846.1    GAIX01013958    JAA78602.1    ODYU01002633    SOQ40393.1    RSAL01000006    RVE54294.1    JTDY01000177    KOB78431.1    GFDF01009987    JAV04097.1    GFDF01009988    JAV04096.1    KP420147    AKJ80167.1    JQ413985    AFI55101.1    GEZM01055068    GEZM01055066    JAV73182.1    PYGN01000659    PSN42693.1    KQ435876    KOX70146.1    GEZM01055069    GEZM01055067    JAV73180.1    KK853510    KDR07077.1    KQ978223    KYM96259.1    KQ981855    KYN34880.1    GFDL01013225    JAV21820.1    GL888002    EGI69273.1    KQ976598    KYM79587.1    ADTU01001034    NNAY01000245    OXU29745.1    KQ414590    KOC70409.1    LBMM01002990    KMQ94103.1    GL441542    EFN64677.1    AAZX01001202    KQ979039    KYN23251.1    KQ760478    OAD60244.1    GDAI01002957    JAI14646.1    KQ982402    KYQ56834.1    KK107293    QOIP01000005    EZA53270.1    RLU23013.1    APGK01035526    BT127946    KB740927    KB631762    AEE62908.1    ENN78000.1    ERL85922.1    CH940654    EDW57690.1    JXUM01118580    KQ566202    KXJ70323.1    OUUW01000010    SPP85917.1    CH916372    EDV98759.1    CH933807    EDW11635.1    KJ188025    AHZ20733.1    JQ855702    AFI45065.1    GL768421    EFZ11390.1    AXCM01000052    AAAB01008846    EAA06245.5    KK854031    PTY09880.1    APCN01004930    AKHW03003216    KYO34957.1    DS232495    EDS42634.1    GAMC01018672    GAMC01018671    GAMC01018669    GAMC01018667    GAMC01018665    JAB87886.1    AFYH01261783    AFYH01261784    AFYH01261785    AFYH01261786    AFYH01261787    DS235354    EEB15119.1    CH479184    EDW37223.1    CH478115    EAT33914.1    GL446987    EFN87008.1    GBYB01008930    JAG78697.1    KP689339    AKO63321.1    GEBQ01010256    JAT29721.1    CH902620    EDV31692.1    AAKN02015647    AAKN02015648    GBXI01015634    JAC98657.1    AXCN02001395    CH379058    EAL34326.2    GDKW01003384    JAI53211.1    KB031119    ELK02811.1    DQ440181    ABF18214.1    KZ288234    PBC31425.1    ACPB03017380    AANG04002876    ABLF02009934    AK340210    BAH70861.1    ABLF02011999    ADFV01183523    ADFV01183524    ADFV01183525    QUSF01000186    RLV88271.1    DQ215561    ACH45136.1    KB202883    ESO87613.1    GBHO01038219    GBHO01013349    JAG05385.1    JAG30255.1    DQ215562    ACH45137.1    AB530141    BAI48089.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000283053    UP000037510    + More
UP000245037    UP000053105    UP000027135    UP000078542    UP000078541    UP000005203    UP000007755    UP000078540    UP000075885    UP000005205    UP000215335    UP000053825    UP000036403    UP000000311    UP000002358    UP000078492    UP000192223    UP000075809    UP000053097    UP000279307    UP000019118    UP000030742    UP000008792    UP000069940    UP000249989    UP000075920    UP000268350    UP000001070    UP000009192    UP000075903    UP000075901    UP000075881    UP000075883    UP000076407    UP000007062    UP000075840    UP000050525    UP000002320    UP000008672    UP000009046    UP000008744    UP000008820    UP000008237    UP000095301    UP000007801    UP000005447    UP000075886    UP000001819    UP000010552    UP000242457    UP000075880    UP000015103    UP000286641    UP000189704    UP000011712    UP000075884    UP000007819    UP000002281    UP000001073    UP000276834    UP000030746    UP000248484    UP000248480    UP000252040    UP000245320    UP000248483   

PRIDE

A5A7A1    Q2F663   

Pfam

PF04275   P-mevalo_kinase

Interpro

IPR005919   Pmev_kin_anim        + More
IPR027417   P-loop_NTPase       

SUPFAM

SSF52540   SSF52540       

ProteinModelPortal

A5A7A1   Q2F663   A0A1E1W532   A0A194RE64   A0A194Q3V4   A0A2H4UZJ1   + More
A0A212FAT1   S4PSD3   A0A2H1VHT5   A0A437BV01   A0A0L7LT63   A0A1L8DCK1   A0A1L8DCB3   A0A0G3F8N7   I1VX03   A0A1Y1LHQ3   A0A2P8YEN0   A0A0M8ZUB2   A0A1Y1LLH5   A0A067QIK8   A0A151IAC4   A0A195F2S9   A0A1Q3F2N5   A0A088ACQ4   F4W991   A0A195B5P9   A0A182PG92   A0A158P0X9   A0A232FGD7   A0A0L7RHW4   A0A0J7KUY5   E2APH8   K7IV48   A0A195EDR7   A0A310SQ09   A0A0K8TKK7   A0A1W4X2P2   A0A151X926   A0A026WB33   J3JXH7   B4M914   A0A182H8J2   A0A182W575   A0A3B0JUY2   B4JPC9   B4KKI5   A0A182VJX8   A0A024BT05   I1VJ81   E9J757   A0A182SFX1   A0A182JZ84   A0A182LX45   A0A182XPI1   Q7PS33   A0A2R7VT85   A0A182HMX9   A0A151NDS3   B0X8P2   W8B3P5   H2ZXB1   E0VP13   B4GKQ7   Q16I28   E2BBC3   A0A0C9RL29   A0A0H4IRI1   A0A1I8N215   A0A1B6M1B1   B3ML74   H0V6W2   A0A0A1WJS5   A0A182QJB3   Q29PG7   A0A0P4VLC4   L5JWF0   Q1HRB3   A0A2A3EI14   A0A182JMP7   T1HQ88   A0A3Q7N464   A0A1U7SYX1   M3VWG9   A0A182N0T1   C4WSJ1   F6V984   X1WUX6   G1RL78   A0A3L8RV14   B5G1H5   V3Z9K9   A0A2Y9EUI6   A0A2Y9E8Q2   A0A0A9YL53   B5G1H6   D0G7E0   A0A341BMM0   A0A2U4A2V2   A0A2Y9LZU6  

PDB

3CH4     E-value=1.00106e-35,     Score=372

KEGG

692835    K13273 phosphomevalonate kinase [EC:2.7.4.2] | (RefSeq) Mpk, MPK_Bm; phosphomevalonate kinase

PATHWAY

00900    Terpenoid backbone biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0006695   GO:0005737   GO:0005524   GO:0004631   GO:0005777   GO:0019287   GO:0005829   GO:0070723   GO:0016459   GO:0000166   GO:0046872   GO:0004190   GO:0006508   GO:0016286  

PANTHER

PTHR13101  

Subcellular location

  

Length:

198

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.48992

Exp number, first 60 AAs:

0.48971

Total prob of N-in:

0.01377

outside

1  -  198

 

 

Pi

199.175221

Theta

199.347182

Tajima's D

-0.506913

CLR

0.006005

CSRT

0.24348782560872

Interpretation

Uncertain