Gene

KWMTBOMO12613

Pre Gene Modal

BGIBMGA001552

Annotation

PREDICTED:_probable_phospholipid-transporting_ATPase_IM_isoform_X3_[Bombyx_mori]

Location

Bomo_Chr21(+):9287844-9337661      View in EpiBrowser

Full name

Phospholipid-transporting ATPase      

Location in the cell

PlasmaMembrane   Reliability : 4.594

CDS

ATGTGTGTCGATGGTGCGGCCGACATGGGAAAGTCCTCGGCGAGAACACATGGCCAAGAAAATGAACGAAGAATCAAAGCGAATAACAGGGAATATAACGCGCAGTTTCGTTATGCCAATAACTACATCAAGACTTCGAAGTATTCGATTATAACGTTCCTGCCGCTGAACTTGTTAGAACAGTTTCAGCGGCTAGCGAACTTTTATTTCTTGTGCCTGTTGGTCCTTCAACTGATCCCGGCTATCTCCTCGCTGACGCCGATAACCACAGCGATACCTCTTATTGGTGTGCTAGCCCTCACTGCCGTCAAGGACGCTTACGACGATTTCCAACGTCATCAAAACGATTCGCAAGTGAATCACAGGCGAGCCAAGACCTTGCGTAATGGCAAGCTTGTGGAGGAGAAATGGGCGTCTGTTCAGGTGGGAGATGTCATCAGGTTGGAGAACGACCAGTTCGTCGCGGCCGACATCCTACTTCTCAGCAGCTCGGAACCTAACGGACTTTGTTACATAGAAACCGCCGAGCTTGATGGGGAGACGAATTTGAAATGTCGTCAGTGCCTTTTGGAGACGGCCGCAATGGGCCAAGACGACGCACAACTGGGCGCGTTCGATGGTGAAATTGTTTGCGAAACGCCCAACAATCTACTTAATAAGTTTGAAGGTACGTTAAGTTGGCGTAACCAACACTTTTCACTCGACAACGATAAGATTCTGTTGCGCGGATGCGTGCTCCGCAACACGTCGTGGTGCTACGGCGTCGTTGTCTTTGCCGGGAAGGACACTAAACTAATGCAGAACTCCGGCAAGACGAAGTTCAAGCGCACCAGCATAGACAGACTACTTAATTTTCTTATCATAGGGATAGTATTCTTTCTGCTGTCTATGTGCGTGTTCTGCACGGTGGCGTGCGGGGTGTGGGAGTGGCTGGTGGGGCGCTACTTCCAGGTGTACCTGCCTTGGGACACGCTGGTGCCGGCCGACCCCACGTGGGGCGCTGTCATCATCGCCCTGCTCGTGTTCTTCTCTTACGCCATCGTGATGAACACTGTCGTGCCTATATCGCTTTATGTTTCTGTTGAAGTTATAAGATTTGCCCAGAGTTTTCTTATTAATTGGGATGAAAAAATGTACTATGAAAAAACTGGTACCGCAGCCAAAGCGCGGACCACCACACTTAACGAAGAACTAGGGCAAATCCAGTATATATTTTCTGATAAAACGGGAACTCTCACGCAAAACATAATGACGTTCAATAAGTGTTCGATAGCGGGCGTTTGCTACGGAGACGTCGTGGACGAGACCACCGGGGAGACTCTGGAGATAAACGAGAGCTCGGAGCCTTTAGATTTCTCGTTCAATCCTGAATACGAGCCGGAGTTTAAGTTCTTCGATCCGACGCTACTAGACGCGGTGAAGCGCGGGGATTCACACGTTCACGACTTCTTTCGTCTCTTGGCGCTTTGTCACACGGTCATGCCGGACCAGAAGAATGGACGGCTCGAATACCAGGCCCAATCGCCAGACGAGTCGGCGCTGGTGTCCGCAGCAAGAAACTTCGGTTTTGTGTTTAGAGAACGTTCGCCTAATAGTATTACAATAGAAGTAATGGGTAACACAGAGGTGTATGAATTGTTATGTATATTAGATTTTAATAATGTTAGAAAAAGAATGTCCGTGATATTGAGGAAGGATGGTGAAATTAGGTTATATACAAAAGGTGCTGATAATGTAATATATGAAAGATTAAAGGCAACTAAAGGAGATGTTAAGTCTAAAACACAGGAACATTTAAATAAATTCGCCGGGGAAGGTTTGAGGACACTGGCGCTGGCGTGGCGGCCGCTGGAGGAGCGCGGGTTCGCCGAGTGGAAGCGCCGCCACCACGCCGCTGCGCTCGCGCTGCACGACCGGGACGAGCAGCTCGACGCCATCTACGAGGAGATCGAGACCGACCTGCTACTGCTGGGCGTGACAGCCATTGAAGATAAACTACAAGATGGAGTACCAGAAACAATAGCGAATCTCAGCATGGCCGGTATAAAGATCTGGGTGTTAACAGGAGATAAACAAGAAACCGCTATAAACATCGGGTACTCGTGTCAGTTGCTGACCGACGACATGGCGGAGGTGTTCGTCGTCGACGGCGCGTCCTACGATGACGTCAACAAGCAGCTGGCCAAGTGCAGGGATTCGATACGGGTCGTCAACACCTTCATGCCGCACGGTCCCCGGTCGTCGGATGCGAAGCGCGACGAGGAGCCTAACGGGGCGGTGTCGGGCCGCGGCGCCAACGTCAAGCTGAACGCGCCCGCCGTCTCCGTCGTCACGTTTAGCAACGAGTACGTGTCTGGGGGCGCGCACACCTCTGAGCCTCACGAGCACGCCAACGACGACTCCAACGGGTTCGCCATCGTCGTCAACGGGCACTCGCTAGTGCACTGTCTGCACCCTAAACTAGAGGAAAAATTTTCAGAAGTAGTATTACACTGTCGATCTGTGATCTGTTGTCGAGTGACTCCACTGCAAAAGGCGATGGTGGTAGAATTAATAAAGAAAAGCAGAAAAGCCGTGACGCTGGCTATAGGCGACGGAGCCAACGACGTGTCCATGATCAAAGCGGCCCACATCGGCGTGGGCATATCAGGCCAAGAGGGCATGCAGGCGGTGCTCGCGTCGGACTACTCCATAGCCCAGTTCCGGTTCCTCCAGCGCCTATTGCTGGTGCACGGGCGCTGGTCCTACTACCGGATGTGTAAATTCCTAAGATATTTCTTCTACAAAAACTTCGCATTCACCGTCTGTCATTTCTGGTTCGCGTTCTTCTGTGGATTCAGTGCGCAGACGGTGTTCGACGAGATGTTCATCTCGGTGTACAACCTGTTCTACACGTCGCTGCCGGTGCTGGCGCTGGGCGTGTTCGAGCAGGACGTGTCGGACGCGACGTCGCTGCAGTTCCCGAAGCTGTACGCGCCGGGACACACCAGCCAGCTCTTCAACAAGACGGAGTTCATCAAGTCCACGCTGCACGGCTGCTTCACCTCGCTCGTGCTCTTCCTCATCCCTTACGGTACGTACAACGATGGGCTGGCGGCGGACGGGCGGGTGCTGTCGGACCACATGCTCCTGGGCAGCGTAGTGGCCACGATACTGATAATAGATAATACAACTCAGATTGCACTGGACACGACGTACTGGACCGTGTTCAACCACGTCACGATCTGGGGCTCGCTCGTGTCGTACTTCGTGCTGGACTACTTCTACAACTACGCCATCGGCGGCCCGTACGTCGGCTCGCTCACCGTGGCGCTCACGCAACCCACCTTCTGGTTCACGGCCGTATTGACCATGATAATCCTGATGGTGCCGGTGGTGTCGTGGCGGCTGGCGAGCGCCCGAGCGCGCGGCACGCTGGCGGAGCGCCTGCGGCTGCGGCAGCGGTGGCGCGGCGCCGCCCCCGCCCCCCGCACTCCCTCCGCCCGCCGCGCGCGCCGCTCCGTGCGCTCCGGGTACGCCTTCGCGCACCAGGAGGGCTTCGGCCGTCTCATCACGTCCGGCAAGATCATGCGCCGCATCCCGCACGCCGACGCCGCCTTCTCCGCGCTCGCCTCGCTGCCCGGGAAGTTCCACGCGCGCCCCTCCTCGCCGCCACCAGAGCCCAAGGCGCCCACGCAGAACCTTGATACAGTCGACCTGTGA

Protein

MCVDGAADMGKSSARTHGQENERRIKANNREYNAQFRYANNYIKTSKYSIITFLPLNLLEQFQRLANFYFLCLLVLQLIPAISSLTPITTAIPLIGVLALTAVKDAYDDFQRHQNDSQVNHRRAKTLRNGKLVEEKWASVQVGDVIRLENDQFVAADILLLSSSEPNGLCYIETAELDGETNLKCRQCLLETAAMGQDDAQLGAFDGEIVCETPNNLLNKFEGTLSWRNQHFSLDNDKILLRGCVLRNTSWCYGVVVFAGKDTKLMQNSGKTKFKRTSIDRLLNFLIIGIVFFLLSMCVFCTVACGVWEWLVGRYFQVYLPWDTLVPADPTWGAVIIALLVFFSYAIVMNTVVPISLYVSVEVIRFAQSFLINWDEKMYYEKTGTAAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSIAGVCYGDVVDETTGETLEINESSEPLDFSFNPEYEPEFKFFDPTLLDAVKRGDSHVHDFFRLLALCHTVMPDQKNGRLEYQAQSPDESALVSAARNFGFVFRERSPNSITIEVMGNTEVYELLCILDFNNVRKRMSVILRKDGEIRLYTKGADNVIYERLKATKGDVKSKTQEHLNKFAGEGLRTLALAWRPLEERGFAEWKRRHHAAALALHDRDEQLDAIYEEIETDLLLLGVTAIEDKLQDGVPETIANLSMAGIKIWVLTGDKQETAINIGYSCQLLTDDMAEVFVVDGASYDDVNKQLAKCRDSIRVVNTFMPHGPRSSDAKRDEEPNGAVSGRGANVKLNAPAVSVVTFSNEYVSGGAHTSEPHEHANDDSNGFAIVVNGHSLVHCLHPKLEEKFSEVVLHCRSVICCRVTPLQKAMVVELIKKSRKAVTLAIGDGANDVSMIKAAHIGVGISGQEGMQAVLASDYSIAQFRFLQRLLLVHGRWSYYRMCKFLRYFFYKNFAFTVCHFWFAFFCGFSAQTVFDEMFISVYNLFYTSLPVLALGVFEQDVSDATSLQFPKLYAPGHTSQLFNKTEFIKSTLHGCFTSLVLFLIPYGTYNDGLAADGRVLSDHMLLGSVVATILIIDNTTQIALDTTYWTVFNHVTIWGSLVSYFVLDYFYNYAIGGPYVGSLTVALTQPTFWFTAVLTMIILMVPVVSWRLASARARGTLAERLRLRQRWRGAAPAPRTPSARRARRSVRSGYAFAHQEGFGRLITSGKIMRRIPHADAAFSALASLPGKFHARPSSPPPEPKAPTQNLDTVDL

Catalytic Activity

ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Similarity

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.

Feature

chain  Phospholipid-transporting ATPase

Uniprot

A0A3S2P7H2   A0A212FAS6   A0A1W4WGI1   A0A1W4W512   A0A1W4W4Z0   A0A182JP59   + More
A0A182M6L0   A0A182IJ29   D6X506   A0A067QZ44   A0A1Y1LAE6   A0A182VPH0   A0A1Y1L8X4   A0A139WAP4   A0A1L8DDT4   A0A182LEE3   A0A182Q512   A0A182Y6N5   V5I8E4   Q7PQW3   W8B3M7   W8AZH5   A0A034V3Z4   A0A0A1X7E8   A0A1A9WIE1   W8BEM1   A0A182P3T7   A0A0L0C3I5   T1PJK4   A0A182U8J3   A0A1B0AFD3   A0A1I8M1V8   A0A182XAK3   A0A0P4VGW7   A0A224XI73   A0A069DXW4   A0A0V0G338   A0A1I8PSV1   A0A1J1HFS6   A0A0Q9WPN5   A0A0Q9WMU9   B4M1Y5   A0A0B4LH22   A0A0P8YDB6   B4NDR3   A0A0M4EXT8   A0A2H1VYH6   A0A0R1E730   A0A1W4UPT3   A0A0B4K669   A0A1W4UMX3   A0A0R3NIU5   E0VRM3   A0A146MAI4   A0A0A9XD29   A0A0N7ZAC6   A0A2J7PNZ2   A0A2J7PNX8   A0A2J7PNX9   A0A2R5LMC8   A0A1W7RAX2   A0A131YJ96   A0A0K8SBF1   T1JEU8   A0A0K8SBG7   A0A1D2N4D5   V5H2L6   T1K886   A0A443R225   A0A1E1XFF3   L7LUF6   V5H495   A0A3S1I231   A0A034V666   A0A210PEG7   A0A0K2U7W1   A0A1W0WRG2   A0A1S3IFH4   A0A1S3IF50   A0A016WML9   A0A016WMH0   A0A016WNL1   A0A158QRU1   U4PBV8   Q7YXV5   U4PBI0   U4PEQ6   U4PRL1   Q9TXV2   A0A3Q7PFF2   A0A3Q7N722   A0A3Q7N0W2   A0A085MC71   A0A085NQE4   A0A2G5TYQ7   A0A2G5TYN3   A0A0V1BHM2   A0A0V1BG57   A0A0V1KUD2  

EC Number

7.6.2.1

Pubmed

22118469    18362917    19820115    24845553    28004739    20966253    + More
25244985    12364791    24495485    25348373    25830018    26108605    25315136    27129103    26334808    17994087    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    15632085    20566863    26823975    25401762    26830274    27289101    25765539    28503490    25576852    28812685    25730766    9851916    24929829   

EMBL

RSAL01000006    RVE54299.1    AGBW02009427    OWR50842.1    AXCM01002117    KQ971381    + More
EEZ97214.2    KK853171    KDR10311.1    GEZM01066269    JAV68027.1    GEZM01066270    JAV68026.1    KYB24975.1    GFDF01009445    JAV04639.1    AXCN02001467    GALX01004830    JAB63636.1    AAAB01008859    EAA08202.6    GAMC01014902    JAB91653.1    GAMC01014903    JAB91652.1    GAKP01021748    JAC37204.1    GBXI01007068    JAD07224.1    GAMC01014904    JAB91651.1    JRES01001043    KNC26014.1    KA648285    AFP62914.1    GDKW01002998    JAI53597.1    GFTR01008685    JAW07741.1    GBGD01000159    JAC88730.1    GECL01003594    JAP02530.1    CVRI01000002    CRK86707.1    CH940651    KRF82341.1    KRF82340.1    EDW65689.2    KRF82339.1    AE014297    AHN57293.1    CH902617    KPU79470.1    CH964239    EDW81882.2    CP012528    ALC48655.1    ODYU01005171    SOQ45776.1    CM000160    KRK03508.1    AFH06386.1    CM000070    KRT00904.1    DS235478    EEB16029.1    GDHC01001858    JAQ16771.1    GBHO01025007    GDHC01016406    JAG18597.1    JAQ02223.1    GDRN01100874    JAI58472.1    NEVH01023281    PNF18041.1    PNF18044.1    PNF18043.1    GGLE01006546    MBY10672.1    GFAH01000089    JAV48300.1    GEDV01010411    JAP78146.1    GBRD01015209    JAG50617.1    JH432130    GBRD01015211    GBRD01015208    JAG50618.1    LJIJ01000231    ODN00134.1    GANP01007238    JAB77230.1    CAEY01001871    NCKU01002575    RWS09297.1    GFAC01001260    JAT97928.1    GACK01009343    JAA55691.1    GANP01012649    JAB71819.1    RQTK01000026    RUS90719.1    GAKP01021747    JAC37205.1    NEDP02076748    OWF34874.1    HACA01016784    CDW34145.1    MTYJ01000056    OQV17784.1    JARK01000193    EYC40856.1    EYC40855.1    EYC40857.1    UZAF01020393    VDO69474.1    BX284604    CDH93219.1    CCD72223.2    CDH93218.1    CDH93217.1    CDH93216.1    CCD72226.1    KL363204    KFD54817.1    KL367481    KFD71690.1    PDUG01000004    PIC32414.1    PIC32415.1    JYDH01000046    KRY36067.1    KRY36069.1    JYDW01000243    KRZ50984.1   

Proteomes

UP000283053    UP000007151    UP000192223    UP000075881    UP000075883    UP000075880    + More
UP000007266    UP000027135    UP000075903    UP000075882    UP000075886    UP000076408    UP000007062    UP000091820    UP000075885    UP000037069    UP000075902    UP000092445    UP000095301    UP000076407    UP000095300    UP000183832    UP000008792    UP000000803    UP000007801    UP000007798    UP000092553    UP000002282    UP000192221    UP000001819    UP000009046    UP000235965    UP000094527    UP000015104    UP000285301    UP000271974    UP000242188    UP000085678    UP000024635    UP000038042    UP000268014    UP000001940    UP000286641    UP000230233    UP000054776    UP000054721   

Pfam

PF16209   PhoLip_ATPase_N        + More
PF16212   PhoLip_ATPase_C

Interpro

IPR030348   ATP8B4        + More
IPR032631   P-type_ATPase_N       
IPR036412   HAD-like_sf       
IPR023298   ATPase_P-typ_TM_dom_sf       
IPR008250   ATPase_P-typ_transduc_dom_A_sf       
IPR001757   P_typ_ATPase       
IPR023299   ATPase_P-typ_cyto_dom_N       
IPR006539   P-type_ATPase_IV       
IPR032630   P_typ_ATPase_c       
IPR018303   ATPase_P-typ_P_site       
IPR023214   HAD_sf       
IPR030350   FetA       
IPR030347   ATP8B2       

SUPFAM

SSF56784   SSF56784        + More
SSF81660   SSF81660       
SSF81653   SSF81653       
SSF81665   SSF81665       

Gene 3D

3.40.1110.10     3.40.50.1000    

ProteinModelPortal

A0A3S2P7H2   A0A212FAS6   A0A1W4WGI1   A0A1W4W512   A0A1W4W4Z0   A0A182JP59   + More
A0A182M6L0   A0A182IJ29   D6X506   A0A067QZ44   A0A1Y1LAE6   A0A182VPH0   A0A1Y1L8X4   A0A139WAP4   A0A1L8DDT4   A0A182LEE3   A0A182Q512   A0A182Y6N5   V5I8E4   Q7PQW3   W8B3M7   W8AZH5   A0A034V3Z4   A0A0A1X7E8   A0A1A9WIE1   W8BEM1   A0A182P3T7   A0A0L0C3I5   T1PJK4   A0A182U8J3   A0A1B0AFD3   A0A1I8M1V8   A0A182XAK3   A0A0P4VGW7   A0A224XI73   A0A069DXW4   A0A0V0G338   A0A1I8PSV1   A0A1J1HFS6   A0A0Q9WPN5   A0A0Q9WMU9   B4M1Y5   A0A0B4LH22   A0A0P8YDB6   B4NDR3   A0A0M4EXT8   A0A2H1VYH6   A0A0R1E730   A0A1W4UPT3   A0A0B4K669   A0A1W4UMX3   A0A0R3NIU5   E0VRM3   A0A146MAI4   A0A0A9XD29   A0A0N7ZAC6   A0A2J7PNZ2   A0A2J7PNX8   A0A2J7PNX9   A0A2R5LMC8   A0A1W7RAX2   A0A131YJ96   A0A0K8SBF1   T1JEU8   A0A0K8SBG7   A0A1D2N4D5   V5H2L6   T1K886   A0A443R225   A0A1E1XFF3   L7LUF6   V5H495   A0A3S1I231   A0A034V666   A0A210PEG7   A0A0K2U7W1   A0A1W0WRG2   A0A1S3IFH4   A0A1S3IF50   A0A016WML9   A0A016WMH0   A0A016WNL1   A0A158QRU1   U4PBV8   Q7YXV5   U4PBI0   U4PEQ6   U4PRL1   Q9TXV2   A0A3Q7PFF2   A0A3Q7N722   A0A3Q7N0W2   A0A085MC71   A0A085NQE4   A0A2G5TYQ7   A0A2G5TYN3   A0A0V1BHM2   A0A0V1BG57   A0A0V1KUD2  

PDB

6A69     E-value=1.0989e-11,     Score=174

KEGG

101741077    K01530 phospholipid-translocating ATPase [EC:7.6.2.1] | (RefSeq) probable phospholipid-transporting

GO

GO:0004012   GO:0005524   GO:0000287   GO:0016021   GO:0005886   GO:0005794   GO:0007030   GO:0045332   GO:0050911   GO:0032880   GO:0005929   GO:0071683   GO:0016125   GO:0015914   GO:0000166   GO:0046872   GO:0004190   GO:0006508   GO:0016286  

PANTHER

PTHR24092   PTHR24092:SF80   PTHR24092:SF52   PTHR24092:SF46  

Subcellular location

Membrane  

Length:

1233

Number of predicted TMHs:

9

Exp number of AAs in TMHs:

203.38343

Exp number, first 60 AAs:

1.43746

Total prob of N-in:

0.23458

outside

1  -  77

TMhelix

78  -  100

inside

101  -  281

TMhelix

282  -  311

outside

312  -  330

TMhelix

331  -  353

inside

354  -  921

TMhelix

922  -  941

outside

942  -  955

TMhelix

956  -  975

inside

976  -  1004

TMhelix

1005  -  1027

outside

1028  -  1036

TMhelix

1037  -  1054

inside

1055  -  1066

TMhelix

1067  -  1089

outside

1090  -  1108

TMhelix

1109  -  1131

inside

1132  -  1233

 

 

Pi

196.092795

Theta

17.68711

Tajima's D

-1.102085

CLR

0.508612

CSRT

0.12094395280236

Interpretation

Uncertain