Gene

KWMTBOMO12609  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001426

Annotation

PREDICTED:_tubulin_polyglutamylase_TTLL13-like_[Amyelois_transitella]

Location

Bomo_Chr21(-):9231445-9234479      View in EpiBrowser

Full name

Tubulin polyglutamylase TTLL13      

Alternative Name

Tubulin--tyrosine ligase-like protein 13

Location in the cell

Nuclear   Reliability : 4.492

CDS

ATGCTCAATATATGGCAGTGCGACAAGAAACGCGTTCTCGAAGAGGATCGAAAACGTATAAGGGATCGATTGTTGCAAACGAATAAATATGCGGAAACCACAACGATCGATGAAAAAGATCGGGAAAAAACTCCTTGGCAAACTCAGATCCAGTGGGAAGAATCGCACCTCGGCAATTTTAGACGAGTTTATCCAGTGGGAGAACAATACGCCTCGCTGTTCCAACAGCCGTCTGGTTCTTTGTACACCGGCACGGCGTCGTCGCGAGCTCGCGGTGACTGTACGCGGATACAGCGAGAGGAATTCCAACAATCGAAAGCTAAAGCGGAGGCCCTGAAAAAACCGTCTCAACCGAAGCCCAAGGAATCGGAAAGTAAAGCTGGCGACGAATCTAGTATCACAGCATCGGCTTCGGTTGCGACACCCAGTACTGAAAAATCAAAAGTTAAAACAAAAGAAAAGGATAAGAGGAAAGAGATAGGGAAAGACAGTGAAGAAGACAAAAATAAGGCAACGAGAATACAGTCCAAACAGCCGATACCAGAAGAGTCCAAGCCTCAATATGTCCTCTGTTCCTTTGAACCAGATCCAATAGTTGAAAAAGATGAACGCGAACGAGTAAACTTACTGGCACAACGTGATTTTCTTATTAGAAGCTATGGAATGTTGGAACAAATCTATTTGATGATGAAGAAAATTGGGACTTTAAGACCGGAAGACGAAAGGAAATATGGTGTCTATGGGCGACTGTCTCTTATTTCTGCCTCACCAAAGACCGACACGAAGAACGCCAAGACGCAAAAGTTAAAGAGGGCTTGCAATAGAAATAAATCAAATAAAGGTGAACTTTAA

Protein

MLNIWQCDKKRVLEEDRKRIRDRLLQTNKYAETTTIDEKDREKTPWQTQIQWEESHLGNFRRVYPVGEQYASLFQQPSGSLYTGTASSRARGDCTRIQREEFQQSKAKAEALKKPSQPKPKESESKAGDESSITASASVATPSTEKSKVKTKEKDKRKEIGKDSEEDKNKATRIQSKQPIPEESKPQYVLCSFEPDPIVEKDERERVNLLAQRDFLIRSYGMLEQIYLMMKKIGTLRPEDERKYGVYGRLSLISASPKTDTKNAKTQKLKRACNRNKSNKGEL

Description

Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step.

Similarity

Belongs to the tubulin--tyrosine ligase family.

Keywords

ATP-binding   Coiled coil   Complete proteome   Ligase   Microtubule   Nucleotide-binding   Reference proteome  

Feature

chain  Tubulin polyglutamylase TTLL13

Uniprot

H9IVZ5   A0A2A4JS85   A0A2A4JR28   A0A2A4JQJ6   A0A194RIJ8   A0A212ERJ6   + More
A0A194Q3X0   A0A2A3E625   A0A088AUZ2   A0A0L7QL04   A0A151J3A7   A0A0M8ZTP0   A0A158NC37   A0A195FKX7   A0A195BG04   E0VJI5   A0A195C9G5   A0A067RUE1   A0A154PIM7   F4WHY8   A0A1B6CES2   E2B8S8   D6W9Z2   A0A1Y1L213   A0A1B6D2B6   A0A091RYQ6   A0A1B6M3Z1   A0A091SW39   A0A093TFX1   E9J688   A0A091TT66   A0A1W4X3Y3   A0A091HL89   A0A0A0AC45   A0A093F514   A0A093BUK2   A0A099YU27   A0A2I0LIE5   A0A087VS31   A0A087R487   A0A093NTM1   A0A093DGV6   A0A091WLT2   A0A1V4JDP6   A0A093I4E3   G3IHT2   A0A182RXQ6   R7UGR0   A4Q9F6   A0A2I0TFU5   U3K958   A6H647   A0A1D5PDA5   F1P1K7   A0A1U7QRS3   C3Y1Y2   A0A177AZR6   H0X0N3   B5DFD2   A0A0D9RX00   R0LK51   A0A3M0K733   A0A2J7QZ71   M7BK08   A0A1S3WEB4   A0A091FXC0   A0A3M0K704   A0A287CVP8   A0A2K5M0T6   G1NDW0   A0A2K5ZC72   K7E3K1   A0A2J7QZ85   A0A2K6AZV2   A0A3M0K8X5   A0A2K5X9E0   A0A2K6FV88   G7P9G1   G7MVY3   G1T8E3   A0A2J7QZ67   A0A2K5X9D6   I3MEN9   A0A096NNA1   F7BNU7   A0A3M0IS70   A0A2K6MGF4   A0A226N5F1   F6VU27   A0A3S0ZT01   A0A3M0IK09  

EC Number

6.-.-.-

Pubmed

19121390    26354079    22118469    21347285    20566863    24845553    + More
21719571    20798317    18362917    19820115    28004739    21282665    23371554    21804562    23254933    17499049    16141072    15489334    19468303    15592404    18563158    15057822    23624526    20838655    17495919    22002653    21993624    19892987   

EMBL

BABH01006347    BABH01006348    NWSH01000780    PCG74270.1    PCG74269.1    PCG74271.1    + More
KQ460325    KPJ15771.1    AGBW02012992    OWR44126.1    KQ459564    KPI99704.1    KZ288356    PBC27213.1    KQ414934    KOC59302.1    KQ980286    KYN16940.1    KQ435883    KOX69756.1    ADTU01011441    ADTU01011442    KQ981491    KYN41001.1    KQ976500    KYM83112.1    DS235222    EEB13541.1    KQ978068    KYM97504.1    KK852460    KDR23459.1    KQ434926    KZC11699.1    GL888170    EGI66217.1    GEDC01029227    GEDC01025366    JAS08071.1    JAS11932.1    GL446373    EFN87900.1    KQ971312    EEZ98564.1    GEZM01066955    JAV67624.1    GEDC01027434    GEDC01017461    JAS09864.1    JAS19837.1    KK935489    KFQ46951.1    GEBQ01009335    JAT30642.1    KK487850    KFQ62543.1    KL437192    KFW93209.1    GL768230    EFZ11676.1    KK463667    KFQ80598.1    KL217594    KFO96651.1    KL871267    KGL91686.1    KK617310    KFV49296.1    KL449542    KFV04544.1    KL885013    KGL72453.1    AKCR02000421    PKK17143.1    KL503450    KFO15423.1    KL226089    KFM08291.1    KL224889    KFW65310.1    KN126163    KFU87117.1    KL411013    KFR02496.1    LSYS01007908    OPJ70249.1    KL206893    KFV86720.1    JH002857    EGW06015.1    AMQN01007840    KB301531    ELU05410.1    AM690757    AK029565    BAC26514.1    CAM84334.1    KZ510986    PKU32670.1    AGTO01011971    AC109232    BC145749    AAI45750.1    AADN05000047    GG666480    EEN65872.1    LWCA01000806    OAF66871.1    AAQR03183173    AAQR03183174    AAQR03183175    AC114460    BC169015    AAI69015.1    AQIB01128854    AQIB01128855    KB743161    EOB00783.1    QRBI01000116    RMC08993.1    NEVH01009073    PNF33880.1    KB526692    EMP36060.1    KL447470    KFO73779.1    RMC08986.1    AGTP01016405    AGTP01016406    PNF33882.1    RMC08991.1    RMC08995.1    RMC08997.1    RMC08999.1    AQIA01063751    AQIA01063752    AQIA01063753    AQIA01063754    AQIA01063755    CM001282    EHH63336.1    CM001259    EHH27595.1    PNF33878.1    AHZZ02031546    QRBI01000294    RMB89349.1    MCFN01000198    OXB62804.1    RQTK01000307    RUS82032.1    RMB89347.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000242457    + More
UP000005203    UP000053825    UP000078492    UP000053105    UP000005205    UP000078541    UP000078540    UP000009046    UP000078542    UP000027135    UP000076502    UP000007755    UP000008237    UP000007266    UP000192223    UP000054308    UP000053858    UP000053641    UP000053872    UP000053286    UP000054081    UP000053283    UP000190648    UP000053584    UP000001075    UP000075900    UP000014760    UP000000589    UP000016665    UP000000539    UP000189706    UP000001554    UP000005225    UP000002494    UP000029965    UP000269221    UP000235965    UP000031443    UP000079721    UP000053760    UP000005215    UP000233060    UP000001645    UP000233140    UP000002280    UP000233120    UP000233100    UP000233160    UP000009130    UP000001811    UP000028761    UP000002281    UP000233180    UP000198323    UP000271974   

PRIDE

H9IVZ5    G3IHT2    A4Q9F6    F7BNU7   

Pfam

PF03133   TTL        + More
PF01266   DAO
PF00995   Sec1
PF06413   Neugrin
PF13328   HD_4
PF17213   Hydin_ADK

Interpro

IPR013815   ATP_grasp_subdomain_1        + More
IPR004344   TTL/TTLL_fam       
IPR006181   D-amino_acid_oxidase_CS       
IPR006076   FAD-dep_OxRdtase       
IPR027754   TTLL6       
IPR027482   Sec-1-like_dom2       
IPR036045   Sec1-like_sf       
IPR010487   NGRN/Rrg9       
IPR003607   HD/PDEase_dom       
IPR001619   Sec1-like       
IPR033768   Hydin_ADK       
IPR027417   P-loop_NTPase       
IPR013783   Ig-like_fold       
IPR033305   Hydin-like       

SUPFAM

SSF56815   SSF56815        + More
SSF52540   SSF52540       

Gene 3D

3.30.1490.20     3.40.50.1910     2.60.40.10    

CDD

cd00077  HDc

ProteinModelPortal

H9IVZ5   A0A2A4JS85   A0A2A4JR28   A0A2A4JQJ6   A0A194RIJ8   A0A212ERJ6   + More
A0A194Q3X0   A0A2A3E625   A0A088AUZ2   A0A0L7QL04   A0A151J3A7   A0A0M8ZTP0   A0A158NC37   A0A195FKX7   A0A195BG04   E0VJI5   A0A195C9G5   A0A067RUE1   A0A154PIM7   F4WHY8   A0A1B6CES2   E2B8S8   D6W9Z2   A0A1Y1L213   A0A1B6D2B6   A0A091RYQ6   A0A1B6M3Z1   A0A091SW39   A0A093TFX1   E9J688   A0A091TT66   A0A1W4X3Y3   A0A091HL89   A0A0A0AC45   A0A093F514   A0A093BUK2   A0A099YU27   A0A2I0LIE5   A0A087VS31   A0A087R487   A0A093NTM1   A0A093DGV6   A0A091WLT2   A0A1V4JDP6   A0A093I4E3   G3IHT2   A0A182RXQ6   R7UGR0   A4Q9F6   A0A2I0TFU5   U3K958   A6H647   A0A1D5PDA5   F1P1K7   A0A1U7QRS3   C3Y1Y2   A0A177AZR6   H0X0N3   B5DFD2   A0A0D9RX00   R0LK51   A0A3M0K733   A0A2J7QZ71   M7BK08   A0A1S3WEB4   A0A091FXC0   A0A3M0K704   A0A287CVP8   A0A2K5M0T6   G1NDW0   A0A2K5ZC72   K7E3K1   A0A2J7QZ85   A0A2K6AZV2   A0A3M0K8X5   A0A2K5X9E0   A0A2K6FV88   G7P9G1   G7MVY3   G1T8E3   A0A2J7QZ67   A0A2K5X9D6   I3MEN9   A0A096NNA1   F7BNU7   A0A3M0IS70   A0A2K6MGF4   A0A226N5F1   F6VU27   A0A3S0ZT01   A0A3M0IK09  

KEGG

101740464    K16582 tubulin polyglutamylase TTLL6/13 [EC:6.-.-.-] | (RefSeq) tubulin polyglutamylase TTLL13-like

GO

GO:0005524   GO:0006464   GO:0016874   GO:0003884   GO:0005874   GO:0006904  

PANTHER

PTHR12241:SF96   PTHR23053  

Length:

283

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00185

Exp number, first 60 AAs:

0

Total prob of N-in:

0.11199

outside

1  -  283

 

 

Pi

191.088318

Theta

182.689187

Tajima's D

0.118442

CLR

12.290691

CSRT

0.4030798460077

Interpretation

Uncertain