Gene

KWMTBOMO12588  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001541

Annotation

PREDICTED:_stress-induced-phosphoprotein_1-like_[Amyelois_transitella]

Location

Bomo_Chr21(+):8642486-8644734      View in EpiBrowser

Full name

Coatomer subunit beta'      

Location in the cell

Cytoplasmic   Reliability : 1.451 Nuclear   Reliability : 2.122

CDS

ATGGATGAAGCCAAGAAACCGACGACAGTGGAGGAGTTAAAAATAAAAGGAAACGAATGCGTCAAAGATGGAAAATTCATCGAAGCTGTTTTACATTATACACAAGCTATCAAAATGGATCCAAACAACTATATTTTGCACAGCAACAGGTCATTCGCCTTTCTGAAACTCGACCAACATTATCTTTCATTACAAGATGCAAATGAAACAGTTAGATTGCAACCTCAATGGGCAAAGGGCTATTTTCGTAGAGCAGAAGTAGAAGCGGCAAGTGGTTTATATGATGAAGCAATTATTTCATATACACATGCTTTACAACTTGACCCACAGAATCAAAAGTTAATAGACTCCATAAAAGAGTTATCAGAAATGCAGGAAAATAGAATAAAAGAAAGTCAAAATGTTGTATGGATTTGTACATGCATTGGTTTAGTAGTTGGAATTATGATTGTAATACTTGATTATAGCTTTACAACGAATCCTACACTAACTAACCCATTCAGCATGGTTGCATTTTCAATGGCATTGTCAGGATTGGGATTTGTTGTAGGAAAAACAACAACTATGATGTCATCATGGAGTGCAGGCAGATCACTGCAGCCGCCAGTTGACTTAGGGTACAATGACAGTTCTCAAGAAAAAGAAGATGTAATACCAGAAAGAAAAAACAAATATAGCAAAGCACAGGCACGTCAAAGGTACAAACAAGGAAAATTGTAG

Protein

MDEAKKPTTVEELKIKGNECVKDGKFIEAVLHYTQAIKMDPNNYILHSNRSFAFLKLDQHYLSLQDANETVRLQPQWAKGYFRRAEVEAASGLYDEAIISYTHALQLDPQNQKLIDSIKELSEMQENRIKESQNVVWICTCIGLVVGIMIVILDYSFTTNPTLTNPFSMVAFSMALSGLGFVVGKTTTMMSSWSAGRSLQPPVDLGYNDSSQEKEDVIPERKNKYSKAQARQRYKQGKL

Description

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Subunit

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.

Similarity

Belongs to the WD repeat COPB2 family.

Uniprot

A0A2A4K593   A0A2H1VS75   A0A437BV85   A0A1E1WPV5   S4NP50   A0A194Q4T1   + More
A0A0N0PCQ4   A0A212F3U0   A0A310SID9   A0A2A3EFW7   A0A2J7PYK5   A0A0L7RFF6   A0A1B0CCI6   A0A0J7NQG3   A0A026WYV3   A0A1B6FIQ3   A0A1B6CJA7   A0A0C9RTH7   R4WTC4   A0A1Y1LN77   A0A1L8DTT0   A0A1L8DTW6   A0A182FLV8   U5EPB8   A0A1W4WVR7   T1JJA0   A0A0P5XEU3   A0A0P4ZJA5   A0A2M4BX45   A0A0P6E0P3   A0A0P5WFN0   A0A0M9A5A2   A0A2M4AYJ5   E9HCE7   A0A0P5GY55   A0A0P5IQD6   A0A0P6AAZ4   W5JA37   A0A2M4BWW1   A0A0P5V1K3   A0A2M3ZBY9   A0A182XCR6   A0A182HXL5   Q7PMS2   A0A182PNY7   D7EIT5   A0A182JUS8   A0A182M9A6   A0A182NNF9   A0A182WCQ0   A0A182YHZ8   T1E1M9   A0A182RKM8   A0A2R7WX88   A0A023F8N7   A0A1S4FCC1   A0A224XW63   A0A0P4VT24   R4FQ14   A0A088AAU4   A0A069DXW7   A0A154PG69   A0A0A9VVV9   Q177T0   A0A1B6LDI6   A0A1J1J645   A0A336KDY4   E2B112   A0A2R5LKT2   A0A0P5XA68   A0A1S4EK13   A0A0N8DBY4   A0A0P4ZVZ1   A0A0P4ZBT4   A0A164TLQ8   A0A023G7U6   A0A0P5U6X7   G3MP38   A0A0V0G5F5   A0A182Q053   A0A0P5ZM29   A0A182H824   A0A131XQQ5   A0A0C9S1T9   A0A131YHD5   A0A224Z236   L7M7N5   E2B3A5   A0A0T6AUJ8   A0A023ENE2   A0A023G1P3   A0A182T3V2   A0A2T7NFV5   A0A0B7AVY9   A0A1E1XVE2   A0A1S3JSM2   A0A0B7AXL2   E9IJC9   A0A433TXY3  

Pubmed

23622113    26354079    22118469    24508170    30249741    23691247    + More
28004739    21292972    20920257    23761445    12364791    14747013    17210077    18362917    19820115    25244985    24330624    25474469    27129103    26334808    25401762    26823975    17510324    20798317    22216098    26483478    28049606    26131772    26830274    28797301    25576852    24945155    29209593    21282665   

EMBL

NWSH01000145    PCG79088.1    ODYU01003826    SOQ43074.1    RSAL01000006    RVE54300.1    + More
GDQN01002188    JAT88866.1    GAIX01011989    JAA80571.1    KQ459585    KPI98415.1    KQ460622    KPJ13516.1    AGBW02010495    OWR48395.1    KQ765119    OAD54140.1    KZ288267    PBC30109.1    NEVH01020350    PNF21392.1    KQ414606    KOC69563.1    AJWK01006818    LBMM01002547    KMQ94680.1    KK107078    QOIP01000011    EZA60324.1    RLU16906.1    GECZ01027438    GECZ01019702    JAS42331.1    JAS50067.1    GEDC01024835    GEDC01023734    JAS12463.1    JAS13564.1    GBYB01010806    JAG80573.1    AK417972    BAN21187.1    GEZM01051242    GEZM01051241    GEZM01051238    GEZM01051237    GEZM01051231    GEZM01051229    JAV75079.1    GFDF01004253    JAV09831.1    GFDF01004260    JAV09824.1    GANO01004767    JAB55104.1    JH431629    GDIP01073269    JAM30446.1    GDIP01216251    JAJ07151.1    GGFJ01008433    MBW57574.1    GDIQ01069474    JAN25263.1    GDIP01100013    JAM03702.1    KQ435742    KOX76736.1    GGFK01012471    MBW45792.1    GL732619    EFX70621.1    GDIQ01257223    JAJ94501.1    GDIQ01209426    JAK42299.1    GDIP01031857    JAM71858.1    ADMH02001854    ETN60856.1    GGFJ01008434    MBW57575.1    GDIP01108362    JAL95352.1    GGFM01005234    MBW25985.1    APCN01005322    AAAB01008968    EAA13278.4    DS497688    EFA12367.1    AXCM01004241    GALA01001514    JAA93338.1    KK855861    PTY24146.1    GBBI01000951    JAC17761.1    GFTR01004063    JAW12363.1    GDKW01000854    JAI55741.1    ACPB03004681    GAHY01000639    JAA76871.1    GBGD01002680    JAC86209.1    KQ434886    KZC10190.1    GBHO01043232    GBRD01012684    GDHC01013647    JAG00372.1    JAG53140.1    JAQ04982.1    CH477371    EAT42438.1    GEBQ01018277    JAT21700.1    CVRI01000073    CRL07869.1    UFQS01000094    UFQT01000094    SSW99280.1    SSX19660.1    GL444767    EFN60638.1    GGLE01005922    MBY10048.1    GDIP01076066    JAM27649.1    GDIP01048775    JAM54940.1    GDIP01208003    JAJ15399.1    GDIP01216250    JAJ07152.1    LRGB01001764    KZS10563.1    GBBM01005536    JAC29882.1    GDIP01117208    JAL86506.1    JO843639    AEO35256.1    GECL01002840    JAP03284.1    AXCN02001910    GDIP01042420    JAM61295.1    JXUM01117463    JXUM01117464    JXUM01117465    JXUM01117466    JXUM01117467    KQ566087    KXJ70410.1    GEFH01000073    JAP68508.1    GBZX01001866    JAG90874.1    GEDV01009834    JAP78723.1    GFPF01012089    MAA23235.1    GACK01005930    JAA59104.1    GL445323    EFN89783.1    LJIG01022765    KRT78831.1    GAPW01003694    JAC09904.1    GBBL01000470    JAC26850.1    PZQS01000013    PVD20036.1    HACG01037942    CEK84807.1    GFAA01000241    JAU03194.1    HACG01037941    CEK84806.1    GL763764    EFZ19345.1    RQTK01000138    RUS86451.1   

Proteomes

UP000218220    UP000283053    UP000053268    UP000053240    UP000007151    UP000242457    + More
UP000235965    UP000053825    UP000092461    UP000036403    UP000053097    UP000279307    UP000069272    UP000192223    UP000053105    UP000000305    UP000000673    UP000076407    UP000075840    UP000007062    UP000075885    UP000007266    UP000075881    UP000075883    UP000075884    UP000075920    UP000076408    UP000075900    UP000015103    UP000005203    UP000076502    UP000008820    UP000183832    UP000000311    UP000079169    UP000076858    UP000075886    UP000069940    UP000249989    UP000008237    UP000075901    UP000245119    UP000085678    UP000271974   

Pfam

PF07719   TPR_2        + More
PF13181   TPR_8
PF00515   TPR_1
PF04053   Coatomer_WDAD
PF00400   WD40
PF10189   Ints3

Interpro

IPR019734   TPR_repeat        + More
IPR011990   TPR-like_helical_dom_sf       
IPR013026   TPR-contain_dom       
IPR013105   TPR_2       
IPR001440   TPR_1       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR036322   WD40_repeat_dom_sf       
IPR020472   G-protein_beta_WD-40_rep       
IPR006692   Coatomer_WD-assoc_reg       
IPR011044   Quino_amine_DH_bsu       
IPR016453   COPB2       
IPR019333   Int_cplx_su3       

SUPFAM

SSF48452   SSF48452        + More
SSF50978   SSF50978       
SSF50969   SSF50969       

Gene 3D

1.25.40.10     2.130.10.10    

ProteinModelPortal

A0A2A4K593   A0A2H1VS75   A0A437BV85   A0A1E1WPV5   S4NP50   A0A194Q4T1   + More
A0A0N0PCQ4   A0A212F3U0   A0A310SID9   A0A2A3EFW7   A0A2J7PYK5   A0A0L7RFF6   A0A1B0CCI6   A0A0J7NQG3   A0A026WYV3   A0A1B6FIQ3   A0A1B6CJA7   A0A0C9RTH7   R4WTC4   A0A1Y1LN77   A0A1L8DTT0   A0A1L8DTW6   A0A182FLV8   U5EPB8   A0A1W4WVR7   T1JJA0   A0A0P5XEU3   A0A0P4ZJA5   A0A2M4BX45   A0A0P6E0P3   A0A0P5WFN0   A0A0M9A5A2   A0A2M4AYJ5   E9HCE7   A0A0P5GY55   A0A0P5IQD6   A0A0P6AAZ4   W5JA37   A0A2M4BWW1   A0A0P5V1K3   A0A2M3ZBY9   A0A182XCR6   A0A182HXL5   Q7PMS2   A0A182PNY7   D7EIT5   A0A182JUS8   A0A182M9A6   A0A182NNF9   A0A182WCQ0   A0A182YHZ8   T1E1M9   A0A182RKM8   A0A2R7WX88   A0A023F8N7   A0A1S4FCC1   A0A224XW63   A0A0P4VT24   R4FQ14   A0A088AAU4   A0A069DXW7   A0A154PG69   A0A0A9VVV9   Q177T0   A0A1B6LDI6   A0A1J1J645   A0A336KDY4   E2B112   A0A2R5LKT2   A0A0P5XA68   A0A1S4EK13   A0A0N8DBY4   A0A0P4ZVZ1   A0A0P4ZBT4   A0A164TLQ8   A0A023G7U6   A0A0P5U6X7   G3MP38   A0A0V0G5F5   A0A182Q053   A0A0P5ZM29   A0A182H824   A0A131XQQ5   A0A0C9S1T9   A0A131YHD5   A0A224Z236   L7M7N5   E2B3A5   A0A0T6AUJ8   A0A023ENE2   A0A023G1P3   A0A182T3V2   A0A2T7NFV5   A0A0B7AVY9   A0A1E1XVE2   A0A1S3JSM2   A0A0B7AXL2   E9IJC9   A0A433TXY3  

PDB

4GCO     E-value=5.27983e-15,     Score=195

KEGG

101738451    no KO assigned | (RefSeq) hsp70-Hsp90 organizing protein 3-like

GO

GO:0016021   GO:0051879   GO:0006886   GO:0030117   GO:0016192   GO:0005198   GO:0030663   GO:0000139   GO:0005515   GO:0003677   GO:0004386   GO:0005524   GO:0005737   GO:0008270   GO:0016787   GO:0004190   GO:0006508   GO:0016286  

PANTHER

PTHR13587  

Subcellular location

Golgi apparatus membrane   The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.   With evidence from 2 publications.
Cytoplasmic vesicle   The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.   With evidence from 2 publications.
COPI-coated vesicle membrane   The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.   With evidence from 2 publications.

Length:

239

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

41.5498

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.99973

inside

1  -  134

TMhelix

135  -  157

outside

158  -  166

TMhelix

167  -  184

inside

185  -  239

 

 

Pi

32.699511

Theta

41.097821

Tajima's D

0.081632

CLR

2.248844

CSRT

0.386680665966702

Interpretation

Uncertain