Gene

KWMTBOMO12531

Pre Gene Modal

BGIBMGA001513

Annotation

PREDICTED:_furin-like_convetase_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr21(+):6039105-6069709      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 2.216

CDS

ATGTGGTATTTAAATCGTGGTGGCGGCCTAGATATGAATGTGATACCGGCGTGGCGGGAAGGCATTACTGGCAGAGGAGTCGTCGTAACGATCCTCGATGATGGCCTCGAAACTGACCACCCTGATCTCGTCGCGAATTACGACCCAGCTGCATCATACGATGTGAACGGGCTCGATCCGGATCCTCAGCCAAGATATGACGTCATAGACTCAAATAGGCACGGGACGAGGTGCGCCGGCGAAGTTGCCGCCACTGCCAACAACTCGCTTTGTGCAGTCGGTGTTGCGTTCGGTGCTCGAGTTGGAGGCGTCCGCATGTTAGATGGTGATGTAACAGATGTCGTCGAAGCAAGATCTTTGAGTCTCAATCCTCAACACGTTGACATATACAGTGCCTCGTGGGGACCGGATGATGATGGAAAGACTGTGGATGGGCCCGGACTATTGGCGACGAGAGCATTCATTGAAGGCGTTACTAAGGGTCGCAACGGAAAAGGTTCGATCTTTGTATGGGCGTCAGGAAACGGCGGTAAAGAGCACGATAACTGCAACTGCGACGGCTACACTAACTCGATTTGGACGTTATCGATATCGTCGGCAACGGAACGCGGCGACGTCCCTTGGTACTCGGAGAAATGCAGCTCGACTTTAGCGGCCACGTACAGCAGTGGCGCAATAAACGAGAACCAGGTGGTAACAACGGACTTGCATCACTCTTGCACAGCCGGTCACACGGGCACATCCGCATCGGCCCCTCTTGCAGCCGGTATATGCGCTTTGGCACTACAGGCTAATAGAGATCTAACATGGCGAGACATGCAGCATATTGTCGTCAGAACAGCTCGTCCCGAGCGACTGAGCTTGAGCGGTGAGTGGAGGATAAACGGCGTGGGACGAAACGTTTCGCATTCGTTTGGCTACGGACTGCTTGATGCGTCGGGCATGGTGCGACTGGCCAAAACATGGCGCACCGTTCCGCCTCAAAGGCGATGCGAACTGGCAGCCCCGAGACCTCATCGGATGATCCCACCGCGATCTGCTATTGCATTGCAGCTGGCCGTAAGTTCGTGTCCCGGAGTTAATTACTTAGAGCACGTTCAAGCCCGAATTTCTTTATCGGCCGCGAGAAGAGGAGATCTTCGCATCACTTTGACTTCGCCGGCTGGAACTAATGTCACTTTGTTGGCGCCTAGGTAA

Protein

MWYLNRGGGLDMNVIPAWREGITGRGVVVTILDDGLETDHPDLVANYDPAASYDVNGLDPDPQPRYDVIDSNRHGTRCAGEVAATANNSLCAVGVAFGARVGGVRMLDGDVTDVVEARSLSLNPQHVDIYSASWGPDDDGKTVDGPGLLATRAFIEGVTKGRNGKGSIFVWASGNGGKEHDNCNCDGYTNSIWTLSISSATERGDVPWYSEKCSSTLAATYSSGAINENQVVTTDLHHSCTAGHTGTSASAPLAAGICALALQANRDLTWRDMQHIVVRTARPERLSLSGEWRINGVGRNVSHSFGYGLLDASGMVRLAKTWRTVPPQRRCELAAPRPHRMIPPRSAIALQLAVSSCPGVNYLEHVQARISLSAARRGDLRITLTSPAGTNVTLLAPR

Similarity

Belongs to the peptidase S8 family.

Uniprot

H9IW82   Q75WU0   A0A2A4JSW4   A0A2A4JU34   A0A2A4JTN4   A0A437BLV5   + More
A0A194PYH4   A0A194RTD3   A0A212F132   A0A1E1WNT8   A0A0L0CIM6   E0VJJ2   A0A2J7PM83   A0A088AAQ3   A0A0J7LBU4   A0A158P1F2   E2AQD1   A0A195E2T0   F4WV05   A0A067QUG0   A0A0N0BEG7   A0A1Y1KRL0   A0A1Y1KWI5   A0A3L8DVL8   A0A0C9RNP4   A0A139WP98   A0A0T6B0U1   A0A1I8PLW2   A0A1W6EVS5   A0A310SF70   Q5QDM4   A0A2H4N0P7   A0A0L7QRG4   A0A154P0X8   A0A139WPK4   A0A1I8MU29   D6W7Q9   T1PJ76   T1PN33   A0A0K8VV29   A0A2A3EP09   A0A1I8PLP7   A0A1A9VPI8   A0A1B6EPA7   A0A0K8WA06   A0A0K8U7N3   A0A1A9ZJR1   W8BUV6   A0A1L8DJ92   A0A1B6C415   A0A1L8DJ27   A0A034VKI2   A0A0P6F4L2   A0A0A1XKM6   A0A0A1WRA0   A0A0K8U6U8   A0A034VHS7   A0A0A1XFN1   A0A0P5AAG6   A0A0P5DT72   A0A0P5I2E1   A0A0P5EFW5   A0A0N8C0C4   A0A0P6FU85   A0A0P5DWH5   A0A182NA15   A0A0P4WFA9   A0A0P5UT48   A0A0P5DSZ4   A0A0P5MFS2   A0A0P4WNV0   A0A182YBC1   A0A0P6FY15   A0A0P5S4I3   A0A0P5UG39   A0A0P6DMX0   A0A0P5CC97   A0A0P5R8L1   A0A0P5VTH9   A0A182P9M0   A0A0P6D1R2   A0A0P5SCK8   A0A0P5N417   A0A0P5JH57   A0A0P5Y3Q8   A0A0P5L036   A0A0P5M6Y8   A0A182X9M8   A0A182VVR6   A0A1A9XU44   A0A146L248   A0A0P5LIC4   A0A0P5UG57   A0A0P5GJU5   A0A182R0F0   A0A2M4CH40   A0A0P5SP43   A0A0P5PKW8   A0A0P5YQS3   A0A0P5PCZ8  

Pubmed

19121390    26354079    22118469    26108605    20566863    21347285    + More
20798317    21719571    24845553    28004739    30249741    18362917    19820115    15544942    25315136    24495485    25348373    25830018    25244985    26823975   

EMBL

BABH01006047    BABH01006048    BABH01006049    BABH01006050    BABH01006051    AB120705    + More
BAC97793.1    NWSH01000634    PCG75135.1    PCG75134.1    PCG75136.1    RSAL01000035    RVE51309.1    KQ459585    KPI98386.1    KQ459896    KPJ19376.1    AGBW02010967    OWR47458.1    GDQN01002618    GDQN01002399    JAT88436.1    JAT88655.1    JRES01000344    KNC32062.1    DS235222    EEB13548.1    NEVH01024418    PNF17448.1    LBMM01000022    KMR05303.1    ADTU01006445    ADTU01006446    GL441723    EFN64345.1    KQ979709    KYN19470.1    GL888382    EGI61972.1    KK852941    KDR13521.1    KQ435834    KOX71564.1    GEZM01077632    JAV63228.1    GEZM01077633    JAV63227.1    QOIP01000004    RLU23979.1    GBYB01012794    GBYB01015142    JAG82561.1    JAG84909.1    KQ971307    KYB29762.1    LJIG01022461    KRT80455.1    KY563396    ARK19805.1    KQ762121    OAD56177.1    AY682745    AAV74200.1    KY653074    ATU47268.1    KQ414784    KOC61091.1    KQ434796    KZC05585.1    KYB29761.1    EFA11330.2    KA648170    AFP62799.1    KA650196    AFP64825.1    GDHF01030935    GDHF01011359    GDHF01009591    GDHF01007046    JAI21379.1    JAI40955.1    JAI42723.1    JAI45268.1    KZ288210    PBC32936.1    GECZ01030000    GECZ01006849    JAS39769.1    JAS62920.1    GDHF01004291    JAI48023.1    GDHF01029721    GDHF01029597    JAI22593.1    JAI22717.1    GAMC01009489    GAMC01009486    JAB97066.1    GFDF01007654    JAV06430.1    GEDC01029050    JAS08248.1    GFDF01007653    JAV06431.1    GAKP01016894    JAC42058.1    GDIQ01053705    JAN41032.1    GBXI01002790    JAD11502.1    GBXI01012955    JAD01337.1    GDHF01030011    GDHF01017425    JAI22303.1    JAI34889.1    GAKP01016893    JAC42059.1    GBXI01004557    JAD09735.1    GDIP01214259    JAJ09143.1    GDIP01150983    JAJ72419.1    GDIQ01219036    JAK32689.1    GDIP01147030    JAJ76372.1    GDIQ01127267    JAL24459.1    GDIQ01053704    JAN41033.1    GDIP01149731    JAJ73671.1    GDRN01075266    JAI63082.1    GDIP01125833    JAL77881.1    GDIP01152082    JAJ71320.1    GDIQ01180048    JAK71677.1    GDRN01075267    JAI63081.1    GDIQ01052058    JAN42679.1    GDIQ01101430    JAL50296.1    GDIP01113486    JAL90228.1    GDIQ01084830    JAN09907.1    GDIP01176434    JAJ46968.1    GDIQ01113370    JAL38356.1    GDIP01095683    JAM08032.1    GDIQ01086435    JAN08302.1    GDIP01141826    JAL61888.1    GDIQ01149912    JAL01814.1    GDIQ01205345    JAK46380.1    GDIP01063437    JAM40278.1    GDIQ01184706    JAK67019.1    GDIQ01162602    JAK89123.1    GDHC01017739    JAQ00890.1    GDIQ01180049    JAK71676.1    GDIP01113485    JAL90229.1    GDIQ01241425    JAK10300.1    AXCN02001521    GGFL01000466    MBW64644.1    GDIP01137331    JAL66383.1    GDIQ01148322    JAL03404.1    GDIP01054992    JAM48723.1    GDIQ01206798    GDIQ01132577    GDIQ01117331    JAL19149.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000053240    UP000007151    + More
UP000037069    UP000009046    UP000235965    UP000005203    UP000036403    UP000005205    UP000000311    UP000078492    UP000007755    UP000027135    UP000053105    UP000279307    UP000007266    UP000095300    UP000053825    UP000076502    UP000095301    UP000242457    UP000078200    UP000092445    UP000075884    UP000076408    UP000075885    UP000076407    UP000075920    UP000092443    UP000075886   

PRIDE

H9IW82    Q75WU0   

Pfam

PF16470   S8_pro-domain        + More
PF01483   P_proprotein
PF00082   Peptidase_S8
PF13855   LRR_8

Interpro

IPR038466   S8_pro-domain_sf        + More
IPR015500   Peptidase_S8_subtilisin-rel       
IPR022398   Peptidase_S8_His-AS       
IPR000209   Peptidase_S8/S53_dom       
IPR023827   Peptidase_S8_Asp-AS       
IPR002884   P_dom       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR006212   Furin_repeat       
IPR032815   S8_pro-domain       
IPR034182   Kexin/furin       
IPR023828   Peptidase_S8_Ser-AS       
IPR008979   Galactose-bd-like_sf       
IPR036852   Peptidase_S8/S53_dom_sf       
IPR032675   LRR_dom_sf       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR001611   Leu-rich_rpt       

SUPFAM

SSF57184   SSF57184        + More
SSF52743   SSF52743       
SSF49785   SSF49785       

Gene 3D

2.60.120.260     3.30.70.850     3.40.50.200     3.80.10.10    

CDD

cd00064  FU
cd04059  Peptidases_S8_Protein_converta

ProteinModelPortal

H9IW82   Q75WU0   A0A2A4JSW4   A0A2A4JU34   A0A2A4JTN4   A0A437BLV5   + More
A0A194PYH4   A0A194RTD3   A0A212F132   A0A1E1WNT8   A0A0L0CIM6   E0VJJ2   A0A2J7PM83   A0A088AAQ3   A0A0J7LBU4   A0A158P1F2   E2AQD1   A0A195E2T0   F4WV05   A0A067QUG0   A0A0N0BEG7   A0A1Y1KRL0   A0A1Y1KWI5   A0A3L8DVL8   A0A0C9RNP4   A0A139WP98   A0A0T6B0U1   A0A1I8PLW2   A0A1W6EVS5   A0A310SF70   Q5QDM4   A0A2H4N0P7   A0A0L7QRG4   A0A154P0X8   A0A139WPK4   A0A1I8MU29   D6W7Q9   T1PJ76   T1PN33   A0A0K8VV29   A0A2A3EP09   A0A1I8PLP7   A0A1A9VPI8   A0A1B6EPA7   A0A0K8WA06   A0A0K8U7N3   A0A1A9ZJR1   W8BUV6   A0A1L8DJ92   A0A1B6C415   A0A1L8DJ27   A0A034VKI2   A0A0P6F4L2   A0A0A1XKM6   A0A0A1WRA0   A0A0K8U6U8   A0A034VHS7   A0A0A1XFN1   A0A0P5AAG6   A0A0P5DT72   A0A0P5I2E1   A0A0P5EFW5   A0A0N8C0C4   A0A0P6FU85   A0A0P5DWH5   A0A182NA15   A0A0P4WFA9   A0A0P5UT48   A0A0P5DSZ4   A0A0P5MFS2   A0A0P4WNV0   A0A182YBC1   A0A0P6FY15   A0A0P5S4I3   A0A0P5UG39   A0A0P6DMX0   A0A0P5CC97   A0A0P5R8L1   A0A0P5VTH9   A0A182P9M0   A0A0P6D1R2   A0A0P5SCK8   A0A0P5N417   A0A0P5JH57   A0A0P5Y3Q8   A0A0P5L036   A0A0P5M6Y8   A0A182X9M8   A0A182VVR6   A0A1A9XU44   A0A146L248   A0A0P5LIC4   A0A0P5UG57   A0A0P5GJU5   A0A182R0F0   A0A2M4CH40   A0A0P5SP43   A0A0P5PKW8   A0A0P5YQS3   A0A0P5PCZ8  

PDB

1P8J     E-value=5.84492e-140,     Score=1275

KEGG

692448    K01349 furin [EC:3.4.21.75] | (RefSeq) furin-like convetase

GO

GO:0004252   GO:0016021   GO:0008236   GO:0016020   GO:0016486   GO:0030173   GO:0016485   GO:0005802   GO:0006508   GO:0043565   GO:0004674   GO:0008270   GO:0045211   GO:0005975   GO:0004553  

Length:

398

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0973

Exp number, first 60 AAs:

0.00026

Total prob of N-in:

0.00566

outside

1  -  398

 

 

Pi

248.629723

Theta

173.284714

Tajima's D

1.204393

CLR

0.212593

CSRT

0.716114194290285

Interpretation

Uncertain