Gene

KWMTBOMO12504

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr21(+):5378512-5381624      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.72

CDS

ATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTCCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACGAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACTTTTGAAGTAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTACGTTCCATCGAAGCACTGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCTCACAACCCAGTCACTGTTACGAGGACCATGGTGGATTGGAATAAGTTGGGCACGTGCCTAGCCGAAGCCGCTCCGCCAATCCTCCCTTACGGCCCGGATTCGAATCTATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACCGATCACATCTCTTCCGCGATCATTAGATCTTCAAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTATCCTCCGAACTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGGCTTCCCACGCATTCAAACCGGATTCGGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCCTAAGCGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCGTACGCCCTTCAGGCCAACCACCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCTGACGCGTTACCCCCCATTACCACTGACGAAGTTAGAGACGCGATCCACAATCTCCAACCTAGGAAGGCATCCGGCTCCGACGGCATCCGCAACCGCGCGCTAAAACTCTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGACAAACGAAACATCTAGTTACCGTCCGATTAGTCTCCTCCCGACGATAGGAAAAATTTACGAACGGCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCTAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATCCTAATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATTTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACTGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATCGGCGGCTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGAATTGACATCAACCCCACGAAAAGCGCAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACATCACTTCGAGCATCCCACTCCGTAGTAGGCGCGCAAACACATCCGCCGTTAGTCCCATCACTCTCTTTGGCCAGCCCATACCGTGGGTCTCGAAGGTCAAATATCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCATATAAAAACGGTACGCGACCGCGCCGCGTTTATTCTAGGACGACTCTATCCAATGCTTTGTAGTCGAAGCAAACTGTCCCTCCGCAATAAGGTAACTCTCTACAAAACTTGTATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACGCAGCCCACACCCACTTGAAATCCCTTCAGGTTATTCAATCAAAATTCTGCAGGATAGCCGTCGGAGCGCCATGGTTCCTTAGGAATGTGGATCTCCACGATGACCTGGAGCTCGACTCATTTAGTAAGTATCTACAGTCGGCATCGCTGCGCCATTTTGAGAAGGCGGCACGACATGAGAACCCTCTCATCGTAGCCGCTGGAAATTACATACCCGACCCAGTAGACCGAATGGTAAACCGTCGACGTCGCCCAAAGCACGTCATTACGGATCCTCCTGATCCATTAACGGTGCTCTTAGGCACCACAAGCACCGGTCACCGTCCTCGTCGAACCCGTTGCTTGCGACGAAGGGCTCGACGAGCGAACTAA

Protein

MVRNDRLTASKGGTAIYYRRALHVVPLDTPSLLHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEVVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEALSELDSDHRPVVMQLGRPHNPVTVTRTMVDWNKLGTCLAEAAPPILPYGPDSNLSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSSELRNLLRVRNAAIRAYDRLPTHSNRIRMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKASGSDGIRNRALKLLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPTNETSSYRPISLLPTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQIAVATMGQWFRKWRIDINPTKSAAVLFKRGRPPNITSSIPLRSRRANTSAVSPITLFGQPIPWVSKVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCSRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAAHTHLKSLQVIQSKFCRIAVGAPWFLRNVDLHDDLELDSFSKYLQSASLRHFEKAARHENPLIVAAGNYIPDPVDRMVNRRRRPKHVITDPPDPLTVLLGTTSTGHRPRRTRCLRRRARRAN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   X1WLB2   A0A023EZE6   A0A2S2Q383   A0A224XF24   A0A3N5Z7I3   Q07995   J9M522   D7EM17   J9LC21   A0A224X6Q4   A0A2S2QEE0   X1WNI2   A0A2J7QR37   A0A087UGF5   A0A2J7PU96   A0A2J7PBY3   A0A2J7QY69   A0A2M4BD66   A0A2J7R7D0   A0A2M4BDA5   A0A224XB44   A0A2M4CV42   A0A2M4BD62   A0A2S2NGV8   A0A2M4CV52   J9KKL3   A0A2J7PDM0   A0A1Y1LKN6   A0A2M4BD67   X1WQI9   A0A2M4BDV6   A0A2M4BEF4   X1WZH0   A0A2M4BEZ9   A0A2J7Q6J2   A0A2S2N814   K7IN67   A0A2H8TF37   A0A224X6S1   A0A2J7PQB5   A0A069DZL8   A0A224X6T4   A0A0A9YJ00   A0A0A9YU04   P21328   J9LFC9   A0A0L0CBP5   A0A224X6U5   A0A2S2R9D4   A0A1Y1KFR3   A0A1B6EGD8   A0A2J7PVX3   A0A0A9YSX4   P21329   A0A2S2P698   A0A224XI99   A0A224XJI0   A0A224X746   A0A224X6R6   A0A087UCW3   D7GYA5   A0A2J7QB68   A0A2A4IUM2   J9JS95   A0A2S2PJG2   A0A142LX26   A0A2S2NH02   A0A352X8G4   A0A224XHW8   A0A0J7MYU2   A0A069DX78   A0A2S2NPG3   A0A2A4K918   A0A2S2N6Q7   A0A2S2PA10   A0A2J7RE85   Q95SX7   A0A224XIB0   A0A2J7R8R8   A0A2J7PP17   A0A0V0G5B6  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    30086797    8387152    20075255    26334808    25401762    2463954    3040362    1714378    26108605    1701254    25527032    30148503    7753626    12537569   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    ABLF02042518    ABLF02057746    GBBI01004571    JAC14141.1    GGMS01002992    MBY72195.1    GFTR01008038    JAW08388.1    RPOV01000134    RPJ78669.1    S59870    AAB26437.2    ABLF02024246    KQ973412    EFA12510.2    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GFTR01008279    JAW08147.1    GGMS01006359    MBY75562.1    ABLF02008153    ABLF02008462    ABLF02008464    NEVH01011985    PNF31054.1    KK119692    KFM76444.1    NEVH01021205    PNF19912.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    GGFJ01001844    MBW50985.1    NEVH01006736    PNF36716.1    GGFJ01001842    MBW50983.1    GFTR01008262    JAW08164.1    GGFL01005012    MBW69190.1    GGFJ01001843    MBW50984.1    GGMR01003407    MBY16026.1    GGFL01004957    MBW69135.1    ABLF02029306    ABLF02029314    ABLF02060138    NEVH01026386    PNF14434.1    GEZM01053022    JAV74219.1    GGFJ01001858    MBW50999.1    ABLF02022418    GGFJ01001857    MBW50998.1    GGFJ01002256    MBW51397.1    ABLF02034467    GGFJ01002257    MBW51398.1    NEVH01017470    PNF24199.1    GGMR01000676    MBY13295.1    GFXV01000908    MBW12713.1    GFTR01008271    JAW08155.1    NEVH01022639    PNF18527.1    GBGD01000415    JAC88474.1    GFTR01008261    JAW08165.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    M22874    M38643    ABLF02023911    JRES01000644    KNC29657.1    GFTR01008251    JAW08175.1    GGMS01017365    MBY86568.1    GEZM01084969    JAV60363.1    GEDC01000337    JAS36961.1    NEVH01020940    PNF20481.1    GBHO01008295    JAG35309.1    M38437    GGMR01012305    MBY24924.1    GFTR01008256    JAW08170.1    GFTR01008257    JAW08169.1    GFTR01008151    JAW08275.1    GFTR01008269    JAW08157.1    KK119261    KFM75202.1    KQ973363    EFA13335.2    NEVH01016302    PNF25823.1    NWSH01007753    PCG62823.1    ABLF02028535    ABLF02028545    GGMR01016905    MBY29524.1    KU543673    AMS38352.1    GGMR01003864    MBY16483.1    DNOY01000259    HBE18313.1    GFTR01008254    JAW08172.1    LBMM01013518    KMQ85605.1    GBGD01000389    JAC88500.1    GGMR01006408    MBY19027.1    NWSH01000032    PCG80496.1    GGMR01000226    MBY12845.1    GGMR01013409    MBY26028.1    NEVH01005277    PNF39135.1    AY060438    AAL25477.1    GFTR01008246    JAW08180.1    NEVH01006721    PNF37225.1    NEVH01023280    PNF18085.1    GECL01003538    JAP02586.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More
UP000037069    UP000218220    UP000036403   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    P21328    P21329    Q95SX7    + More

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   X1WLB2   A0A023EZE6   A0A2S2Q383   A0A224XF24   A0A3N5Z7I3   Q07995   J9M522   D7EM17   J9LC21   A0A224X6Q4   A0A2S2QEE0   X1WNI2   A0A2J7QR37   A0A087UGF5   A0A2J7PU96   A0A2J7PBY3   A0A2J7QY69   A0A2M4BD66   A0A2J7R7D0   A0A2M4BDA5   A0A224XB44   A0A2M4CV42   A0A2M4BD62   A0A2S2NGV8   A0A2M4CV52   J9KKL3   A0A2J7PDM0   A0A1Y1LKN6   A0A2M4BD67   X1WQI9   A0A2M4BDV6   A0A2M4BEF4   X1WZH0   A0A2M4BEZ9   A0A2J7Q6J2   A0A2S2N814   K7IN67   A0A2H8TF37   A0A224X6S1   A0A2J7PQB5   A0A069DZL8   A0A224X6T4   A0A0A9YJ00   A0A0A9YU04   P21328   J9LFC9   A0A0L0CBP5   A0A224X6U5   A0A2S2R9D4   A0A1Y1KFR3   A0A1B6EGD8   A0A2J7PVX3   A0A0A9YSX4   P21329   A0A2S2P698   A0A224XI99   A0A224XJI0   A0A224X746   A0A224X6R6   A0A087UCW3   D7GYA5   A0A2J7QB68   A0A2A4IUM2   J9JS95   A0A2S2PJG2   A0A142LX26   A0A2S2NH02   A0A352X8G4   A0A224XHW8   A0A0J7MYU2   A0A069DX78   A0A2S2NPG3   A0A2A4K918   A0A2S2N6Q7   A0A2S2PA10   A0A2J7RE85   Q95SX7   A0A224XIB0   A0A2J7R8R8   A0A2J7PP17   A0A0V0G5B6  

PDB

6AR3     E-value=0.000853313,     Score=104

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

899

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.928789999999999

Exp number, first 60 AAs:

0.02127

Total prob of N-in:

0.02104

outside

1  -  899

 

 

Pi

144.478244

Theta

30.582293

Tajima's D

0.962329

CLR

10.327591

CSRT

0.657267136643168

Interpretation

Uncertain