Gene

KWMTBOMO12459

Pre Gene Modal

BGIBMGA001484

Annotation

PREDICTED:_ubiquitin_carboxyl-terminal_hydrolase_3-like_[Amyelois_transitella]

Location

Bomo_Chr21(-):4403583-4411632      View in EpiBrowser

Full name

Ubiquitinyl hydrolase 1      

Location in the cell

Nuclear   Reliability : 4.357

CDS

ATGGAATGCGAACATTTGTTAGATAACGTCAAATTGGAACAAATCAAAGTCGAGGACACAAAAATCACAAAGAACTTCAGTTGTTCAGAATGTTCAGTACCAGAACAGAACTGGCTTTGCCTACATTGTGGTGTGGTGAACTGTGGTCGTTATGTAAATGGCCATGCGAAGAACCATGCTGACACACTCGGACACCAGCTTTGCATTAGCTGTGATGCTTATTCTGTATATTGTTACAAATGTGATGATTACATTATAAATGATACTGAGAACAATATAGATAAAATAAGGCAATGTATTATACGGATTAGGCAACAAAATGATGAAAAACAAAACAGTAGAGAAAAGCAGGAAGATAGCAGACAAGATGAAGATGACTGTGATGCCAATATACCTGGTTTGGTCACTGCTCCAGATGATATAGTGCTCAATGTTATTGAAGGAGATATAGCAGTGCAACCAACAAGCTCTTCTTTAGATCCTCACAGTACAGAAATTGAAAACTGTGATAGTAAACTTGATAAATGTATTAAGGGGACTGAAGAATCTATACGAAGTCTTAGACCAAGATCGAGGAAGAGAACTCATTCCGAGGACAGTAGCTCAACTGAAAACTCATTACAGATAAACAGAAAAGATAAAAAACGATCGCCTTCTAATGGAAAGCTTCAGAGAGAAAAAAAAGTTGTAGGATTAAAGAATTTAGGCAACACATGTTTCATGAATGCAGTTCTTCAGAGTCTGAACAATATACAAGAATTTAGTTGTTATTTCAATCAATTACCTTCTTTGGAGATGAAGGCAAATGGCAGGAAGGTGTATCATTCAAGGAGTTATACACGACAGGAGATGAATGATGTTGTAATGGCTGAAGAACTCCGTAAGGTGTTGATAAATCTCAATACTGGTGGTTGCGGTTCGAAAGGTGCTATTTCACCGGAGTGCTTGTTCCTTGTGATTTGGAAGGTGGTACCGAGGTTTAGGGGCTATCAGCAGCAGGACGCACATGAGTTTCTCAGATACATGCTAGACAGATTACACACGGAGCTGTTGCAACTGCTGCCCCCCGAGAAGCCGGAGCCCGGGTTCGTGGCGCGGCCTCCGTCGGCGTCCATCGTCACCGCTGTGTTCGGGGGAACATTGCAGAGCGAGGTTCGTTGCTTGGCGTGCGGCACGGAAAGCAAGAAGTACGACCCTTTCTTAGATCTCTCACTGGAATTACCAGAAGTCGGAAGAAATGATACGCCCGTCGCTCTTTCGGATTGTCTCGCCAGCTTTGTACAGGTCGAGGAGTTGGCCGACACGGAGCGTTACTTCTGCAGCAGCTGCAAATGTAAGCAGAAGTCCACTAAGCAGTTCTGGATTCGGAGGTTGCCGAACGTTTTGTGTCTACATTTGAAAAGGTTTCGGTGGCACAATTATTTCAGGACCAAGGTGGACACTTCGATCTCGTTCCCGCTGCGCGCGCTGGACGTGTCCCGCTTCGTGCGCGACGTGCGGCGCGCCGAGCACGACGCGCTGCTGTACGACCTCGCCGCCGTCATCGTGCACCACGGCTCCGGGGCCGGGTCTGGTCACTACACCGCGTTCGCTATAAACGAGGAGCAGTGGTTCCACTTCAACGACCACACGGTGCGCGCCGCGGACTCGCACGCCGTCGCCAGCTGCAAGCCCTACATACTCTTCTACATCCGCAGGGAACTGTCGCTGTGA

Protein

MECEHLLDNVKLEQIKVEDTKITKNFSCSECSVPEQNWLCLHCGVVNCGRYVNGHAKNHADTLGHQLCISCDAYSVYCYKCDDYIINDTENNIDKIRQCIIRIRQQNDEKQNSREKQEDSRQDEDDCDANIPGLVTAPDDIVLNVIEGDIAVQPTSSSLDPHSTEIENCDSKLDKCIKGTEESIRSLRPRSRKRTHSEDSSSTENSLQINRKDKKRSPSNGKLQREKKVVGLKNLGNTCFMNAVLQSLNNIQEFSCYFNQLPSLEMKANGRKVYHSRSYTRQEMNDVVMAEELRKVLINLNTGGCGSKGAISPECLFLVIWKVVPRFRGYQQQDAHEFLRYMLDRLHTELLQLLPPEKPEPGFVARPPSASIVTAVFGGTLQSEVRCLACGTESKKYDPFLDLSLELPEVGRNDTPVALSDCLASFVQVEELADTERYFCSSCKCKQKSTKQFWIRRLPNVLCLHLKRFRWHNYFRTKVDTSISFPLRALDVSRFVRDVRRAEHDALLYDLAAVIVHHGSGAGSGHYTAFAINEEQWFHFNDHTVRAADSHAVASCKPYILFYIRRELSL

Catalytic Activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Similarity

Belongs to the peptidase C19 family.

Uniprot

A0A3S2NMK7   A0A2H1WHJ1   A0A194RGP7   A0A212F5Y6   A0A194PZ89   A0A2A4JXX5   + More
A0A2J7PYF5   A0A067RRV7   A0A2J7PYE9   A0A0K8SUV4   A0A2M4BH56   A0A2M4CG37   A0A2M4BGR6   A0A2M4CG10   A0A2M3Z7G8   A0A2M4BGI0   A0A2M4ADH4   A0A182F2U1   A0A182Y9A8   A0A182R2J3   A0A182NT57   A0A084VJ93   A0A182QVN5   A0A0A9XV48   A0A182JZL9   A0A182WA05   A0A1B0GQ88   A0A182P5G7   A0A1Q3FBS7   A0A1Q3FBD5   A0A1Q3FB42   A0A1Q3FCY2   A0A0C9R1E4   A0A1L8DTC5   A0A088ANM9   Q17BE1   A0A0L7RDN2   V9IHC8   W5JGA3   A0A1B6EMR0   E2BLN2   E0VJF6   A0A2R7WDH0   A0A1J1IFZ5   Q7Q848   A0A1S4GZA3   A0A224XJK7   B0WPV0   A0A1B6CBZ9   T1HCI3   A0A336M2R1   A0A182G8Z3   A0A2A3EIJ8   A0A182G277   A0A2C9M8A0   A0A2J7PYI5   R7U8Z1   A0A3L8DGS3   A0A151IEB8   A0A195EN71   A0A158NEI9   E9ID72   A0A195FLG3   A0A210QYW9   A0A195BUZ7   A0A310SR20   A0A2P6LAW3   K1QKV6   A0A182VKN6   A0A0J7L9I6   A0A1W5B1P7   A0A1S3H889   A0A182X610   A0A2P8ZCS1   A0A182LJZ8   K7FF76   A0A093HVI6   A0A401PQ64   F6ZBV9   A0A091UEM0   A0A2Y9QTT3   A0A337SU26   A0A340Y6Z8   A0A2K6RZF5   A0A2K6RZJ0   A0A286X9C3   I3LJX6   A0A383YT28   A0A2U4CD91   A0A2Y9EXQ1  

EC Number

3.4.19.12

Pubmed

26354079    22118469    24845553    25244985    24438588    25401762    + More
26823975    17510324    20920257    23761445    20798317    20566863    12364791    26483478    15562597    23254933    30249741    21347285    21282665    28812685    22992520    29403074    20966253    17381049    30297745    17495919    17975172    21993624    30723633   

EMBL

RSAL01000033    RVE51504.1    ODYU01008712    SOQ52535.1    KQ460211    KPJ16500.1    + More
AGBW02010111    OWR49150.1    KQ459585    KPI98358.1    NWSH01000372    PCG76875.1    NEVH01020350    PNF21371.1    KK852463    KDR23420.1    PNF21373.1    GBRD01008759    JAG57062.1    GGFJ01003182    MBW52323.1    GGFL01000105    MBW64283.1    GGFJ01003000    MBW52141.1    GGFL01000104    MBW64282.1    GGFM01003637    MBW24388.1    GGFJ01003001    MBW52142.1    GGFK01005451    MBW38772.1    ATLV01013476    KE524860    KFB38037.1    AXCN02000729    GBHO01035418    GBHO01022484    GDHC01011881    JAG08186.1    JAG21120.1    JAQ06748.1    AJVK01006587    GFDL01010092    JAV24953.1    GFDL01010151    JAV24894.1    GFDL01010254    JAV24791.1    GFDL01009628    JAV25417.1    GBYB01009974    JAG79741.1    GFDF01004423    JAV09661.1    CH477322    EAT43603.1    KQ414613    KOC69102.1    JR045755    AEY60047.1    ADMH02001599    ETN61900.1    GECZ01030551    JAS39218.1    GL449036    EFN83366.1    DS235222    EEB13512.1    KK854643    PTY17588.1    CVRI01000047    CRK97369.1    AAAB01008944    EAA10095.4    GFTR01006418    JAW10008.1    DS232030    EDS32538.1    GEDC01026473    JAS10825.1    ACPB03005019    UFQS01000114    UFQT01000114    SSW99878.1    SSX20258.1    JXUM01153045    JXUM01153046    KQ571607    KXJ68147.1    KZ288254    PBC30821.1    JXUM01039461    KQ561205    KXJ79349.1    PNF21372.1    AMQN01008733    KB303858    ELU02606.1    QOIP01000008    RLU19645.1    KQ977871    KYM99204.1    KQ978625    KYN29611.1    ADTU01013450    ADTU01013451    GL762454    EFZ21430.1    KQ981490    KYN41176.1    NEDP02001165    OWF53968.1    KQ976401    KYM92407.1    KQ759892    OAD62106.1    MWRG01000572    PRD35713.1    JH817083    EKC37407.1    LBMM01000198    KMR04508.1    PYGN01000102    PSN54291.1    AGCU01110667    AGCU01110668    AGCU01110669    AGCU01110670    AGCU01110671    KK398251    KFV58523.1    BFAA01011159    GCB75264.1    KK448918    KFQ72468.1    AANG04001761    AAKN02009840    AAKN02009841    AAKN02009842    AAKN02009843    AAKN02009844    AEMK02000004    DQIR01280775    HDC36253.1   

Proteomes

UP000283053    UP000053240    UP000007151    UP000053268    UP000218220    UP000235965    + More
UP000027135    UP000069272    UP000076408    UP000075900    UP000075884    UP000030765    UP000075886    UP000075881    UP000075920    UP000092462    UP000075885    UP000005203    UP000008820    UP000053825    UP000000673    UP000008237    UP000009046    UP000183832    UP000007062    UP000002320    UP000015103    UP000069940    UP000249989    UP000242457    UP000076420    UP000014760    UP000279307    UP000078542    UP000078492    UP000005205    UP000078541    UP000242188    UP000078540    UP000005408    UP000075903    UP000036403    UP000192224    UP000085678    UP000076407    UP000245037    UP000075882    UP000007267    UP000288216    UP000002280    UP000248480    UP000011712    UP000265300    UP000233220    UP000005447    UP000008227    UP000261681    UP000245320    UP000248484   

Pfam

PF02148   zf-UBP        + More
PF00443   UCH

Interpro

IPR013083   Znf_RING/FYVE/PHD        + More
IPR028889   USP_dom       
IPR001394   Peptidase_C19_UCH       
IPR001607   Znf_UBP       
IPR018200   USP_CS       
IPR038765   Papain-like_cys_pep_sf       

SUPFAM

SSF54001   SSF54001       

Gene 3D

3.30.40.10    

ProteinModelPortal

A0A3S2NMK7   A0A2H1WHJ1   A0A194RGP7   A0A212F5Y6   A0A194PZ89   A0A2A4JXX5   + More
A0A2J7PYF5   A0A067RRV7   A0A2J7PYE9   A0A0K8SUV4   A0A2M4BH56   A0A2M4CG37   A0A2M4BGR6   A0A2M4CG10   A0A2M3Z7G8   A0A2M4BGI0   A0A2M4ADH4   A0A182F2U1   A0A182Y9A8   A0A182R2J3   A0A182NT57   A0A084VJ93   A0A182QVN5   A0A0A9XV48   A0A182JZL9   A0A182WA05   A0A1B0GQ88   A0A182P5G7   A0A1Q3FBS7   A0A1Q3FBD5   A0A1Q3FB42   A0A1Q3FCY2   A0A0C9R1E4   A0A1L8DTC5   A0A088ANM9   Q17BE1   A0A0L7RDN2   V9IHC8   W5JGA3   A0A1B6EMR0   E2BLN2   E0VJF6   A0A2R7WDH0   A0A1J1IFZ5   Q7Q848   A0A1S4GZA3   A0A224XJK7   B0WPV0   A0A1B6CBZ9   T1HCI3   A0A336M2R1   A0A182G8Z3   A0A2A3EIJ8   A0A182G277   A0A2C9M8A0   A0A2J7PYI5   R7U8Z1   A0A3L8DGS3   A0A151IEB8   A0A195EN71   A0A158NEI9   E9ID72   A0A195FLG3   A0A210QYW9   A0A195BUZ7   A0A310SR20   A0A2P6LAW3   K1QKV6   A0A182VKN6   A0A0J7L9I6   A0A1W5B1P7   A0A1S3H889   A0A182X610   A0A2P8ZCS1   A0A182LJZ8   K7FF76   A0A093HVI6   A0A401PQ64   F6ZBV9   A0A091UEM0   A0A2Y9QTT3   A0A337SU26   A0A340Y6Z8   A0A2K6RZF5   A0A2K6RZJ0   A0A286X9C3   I3LJX6   A0A383YT28   A0A2U4CD91   A0A2Y9EXQ1  

PDB

2Y6E     E-value=1.65907e-41,     Score=428

KEGG

101742552    K11986 ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12] | (RefSeq) ubiquitin carboxyl-terminal

GO

GO:0036459   GO:0046872   GO:0016579   GO:0008270   GO:0006511   GO:0016021   GO:0005737   GO:0031647   GO:0000278   GO:0006281   GO:0090543   GO:0000790   GO:0016578   GO:0004843   GO:0005654   GO:0042393   GO:0036464   GO:0005634   GO:0005622   GO:0015934   GO:0005216   GO:0045211   GO:0005975   GO:0004553  

Length:

570

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01042

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00057

outside

1  -  570

 

 

Pi

192.041483

Theta

148.705511

Tajima's D

0.796257

CLR

1.591189

CSRT

0.600569971501425

Interpretation

Uncertain