Gene

KWMTBOMO12406

Pre Gene Modal

BGIBMGA012426

Annotation

PREDICTED:_serine_protease_snake-like_[Bombyx_mori]

Location

Bomo_Chr21(-):2391459-2402856      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.292 Extracellular   Reliability : 1.65

CDS

ATGCTAATTGTCACGTTACTTTGTGTGGTGCTTCCATTGGTTGCAACGTCTGCTGAACGAATTAATGAAACAACGGATTTCACAATAAACAAAAGTCTCTCCAACGAAGACAAATGGATTTGGGGACCTGTTGATGATAATATTCATAGTAGAACGCTGGCAGAAAATAATACAAAAAGCCAACCCTTGATACAAACATCACCTCGAACTCCAGTCGACCAAAATGAAGATCCTTGCGTCGCTTATGATCCTCCAAAACCAAATTTCAGTCTACCTGGAAGACGTATTAGTGAAGTCAAATGTCAGGAGTACATATGGGAATTAGAAACGAAATCAATAAAAGCTCTAAGAGATTTTAAGTGCCAACAAACAAATCCTGGACGCATTAAAAAAATACCAATAATCGTTGGAGGACGAGATACAATCCCCGGTGAATTTCTTCATATGGGTGCTATAGGATGGAAGGGTGTTAGAAATAACTGGCAATTTAAGTGCGGTGGGTCACTGATCAGTCCCAGTTACATTCTCACCGCAGCTCATTGCTCTGTGGCTTCGGCAAGCGATACCACATTACAGGATGAAAATGAAATTAGGTTGAAAAAGTACGACGTTGGTATCAAGAGGATTATCGTCCATCCAGAATACAATCCGCCGAATAAATATTACGATATAGCTTTAATGGAATTAGACCATGACGTTGAATTTAGCAATTATGTCTTCCCTTCGTGTCTCTGGAGTAAGCCTGATATAGCGGAATTAGGAACTTCTGCCACTGTGACCGGCTGGGGTGCTTTACACGAAGGAAGTTCAGATATCTCTCCGGAGCTGCAAGCTGGCGATGTCAATGTGATCGACAGTGATATGTGCGATCAACTTCTCCAAGCATATTGCAATAGGAACTGGTGTGGCTTGATGGATCATCAGCTCTGTGCGGGGAAACTAACAGGCGGCGTCGACTCTTGTCAGGGTGACTCCGGAGGACCACTTCAAGTCAAAATTAACTTAAAGGTAGACTCCGCTTACAACATCTACCATATTATCGGAGTGACGTCATTCGGCATCGGATGTGCTCAAGCGAACACACCCGGGATTTATACTCGGGTATCCAGTTTCATTGACTGGATAGAAAATATCGTATGGCCCTGA

Protein

MLIVTLLCVVLPLVATSAERINETTDFTINKSLSNEDKWIWGPVDDNIHSRTLAENNTKSQPLIQTSPRTPVDQNEDPCVAYDPPKPNFSLPGRRISEVKCQEYIWELETKSIKALRDFKCQQTNPGRIKKIPIIVGGRDTIPGEFLHMGAIGWKGVRNNWQFKCGGSLISPSYILTAAHCSVASASDTTLQDENEIRLKKYDVGIKRIIVHPEYNPPNKYYDIALMELDHDVEFSNYVFPSCLWSKPDIAELGTSATVTGWGALHEGSSDISPELQAGDVNVIDSDMCDQLLQAYCNRNWCGLMDHQLCAGKLTGGVDSCQGDSGGPLQVKINLKVDSAYNIYHIIGVTSFGIGCAQANTPGIYTRVSSFIDWIENIVWP

Similarity

Belongs to the peptidase S1 family.
Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

Q5MPC5   H9JSB6   Q1HPQ6   I4DLF7   A0A2H1W7F8   A0A2H1WUS1   + More
A0A437BB50   A0A212EPD4   A0A3S2NHC8   A0A3S2LZB7   A0A2A4JFQ7   A0A212F1T1   A0A2A4JE90   A0A194RAB5   A0A194R9C5   A0A437BB20   A0A212EHP9   I4DLF6   A0A194PUL8   A0A437BB81   A0A3S2TB84   A0A437BWN7   A0A194PLU8   G9F9H9   G9F9H7   A0A2A4JQ23   A0A2W1B5H2   H9IWW2   A0A212F1E7   A0A2H1VIS4   I4DMI4   A0A194Q611   A0A194RM65   Q5MGE5   I4DQ94   A0A0N0PBX6   E0V917   A0A067RX29   Q9XY63   A0A1J1J158   A0A437BB41   A0A182LU74   A0A0L0CNX7   A0A182H431   A0A1I8NBH8   A0A1S4FI15   T1H2V5   A0A194RAY6   Q16ZZ9   A0A1Y9HF60   A0A084VW05   A0A182XWS6   A0A0A1WIS9   A0A0T6B1X0   A0A3S2NY81   E0VUP7   A0A1I8NXE1   A0A182QVG9   A0A182GA96   A0A182VY34   A0A182JNP3   A0A1I8NXF4   A0A1I8NXE7   A0A1I8NXD9   A0A1Q3FR28   X1WIF2   J9HYX9   Q170A0   A0A1Q3FRL8   A0A1V1FKN1   B0XFN4   A0A182U5J8   D6W6R5   A0A2J7RDN5   A0A0M8ZW49   A0A182X8T1   A0A1V1G565   A0A182UYI4   A0A1B0CS99   A0A1W4WXU4   Q9Y1K5   A0A2J7RDN0   A0A023EMY9   A0A182L6V0   Q7QAC0   A0A2M4AP36   B4N9Y9  

Pubmed

15944088    19121390    22651552    22118469    26354079    28756777    + More
16023793    20566863    24845553    26108605    26483478    25315136    17510324    24438588    25244985    25830018    28410430    18362917    19820115    10646969    24945155    20966253    12364791    14747013    17210077    17994087   

EMBL

AY672785    AAV91007.1    BABH01033742    DQ443346    ABF51435.1    AK402125    + More
BAM18747.1    ODYU01006800    SOQ48987.1    ODYU01011151    SOQ56716.1    RSAL01000098    RVE47614.1    AGBW02013495    OWR43336.1    RVE47611.1    RVE47596.1    NWSH01001694    PCG70404.1    AGBW02010816    OWR47692.1    PCG70405.1    KQ460473    KPJ14444.1    KPJ14443.1    RVE47617.1    AGBW02014853    OWR40990.1    AK402124    BAM18746.1    KQ459591    KPI97101.1    RVE47613.1    RSAL01001256    RVE40868.1    RSAL01000002    RVE54897.1    KQ459600    KPI94302.1    JN033724    AEW46877.1    JN033722    AEW46875.1    NWSH01000865    PCG73808.1    KZ150313    PZC71449.1    BABH01021026    AGBW02010907    OWR47533.1    ODYU01002797    SOQ40740.1    AK402502    BAM19124.1    KQ459463    KPJ00445.1    KQ459995    KPJ18524.1    AY829841    AAV91455.1    AK403997    BAM20084.1    KQ460736    KPJ12593.1    DS234988    EEB09873.1    KK852411    KDR24454.1    AF053921    AAD21841.1    CVRI01000064    CRL05174.1    RVE47618.1    AXCM01003236    JRES01000232    KNC33159.1    JXUM01108692    KQ565255    KXJ71168.1    CAQQ02171618    CAQQ02171619    KPJ14445.1    CH477477    EAT40291.1    ATLV01017365    KE525164    KFB42149.1    GBXI01015872    JAC98419.1    LJIG01016282    KRT81069.1    RVE47612.1    DS235787    EEB17103.1    AXCN02001168    JXUM01050760    KQ561661    KXJ77889.1    GFDL01004975    JAV30070.1    ABLF02031950    ABLF02031955    CH477450    EJY57695.1    EAT40292.1    GFDL01004972    JAV30073.1    FX985359    BAX07372.1    DS232947    EDS26915.1    KQ971307    EFA11559.1    NEVH01005287    PNF38945.1    KQ435821    KOX72340.1    FX985323    BAX07336.1    AJWK01025808    AJWK01025809    AF117750    AAD38336.1    PNF38947.1    GAPW01002866    JAC10732.1    AAAB01008898    EAA09190.2    GGFK01009233    MBW42554.1    CH964232    EDW81744.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000218220    UP000053240    UP000053268    + More
UP000009046    UP000027135    UP000183832    UP000075883    UP000037069    UP000069940    UP000249989    UP000095301    UP000015102    UP000008820    UP000075900    UP000030765    UP000076408    UP000095300    UP000075886    UP000075920    UP000075881    UP000007819    UP000002320    UP000075902    UP000007266    UP000235965    UP000053105    UP000076407    UP000075903    UP000092461    UP000192223    UP000075882    UP000007062    UP000007798   

PRIDE

H9JSB6    Q1HPQ6    H9IWW2   

Pfam

PF00089   Trypsin        + More
PF02932   Neur_chan_memb
PF02931   Neur_chan_LBD
PF12032   CLIP
PF03587   EMG1

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR033116   TRYPSIN_SER       
IPR006029   Neurotrans-gated_channel_TM       
IPR006202   Neur_chan_lig-bd       
IPR036734   Neur_chan_lig-bd_sf       
IPR036719   Neuro-gated_channel_TM_sf       
IPR018000   Neurotransmitter_ion_chnl_CS       
IPR006201   Neur_channel       
IPR022700   CLIP       
IPR005304   Rbsml_bgen_MeTrfase_EMG1/NEP1       
IPR029028   Alpha/beta_knot_MTases       
IPR029026   tRNA_m1G_MTases_N       

SUPFAM

SSF50494   SSF50494        + More
SSF90112   SSF90112       
SSF63712   SSF63712       
SSF75217   SSF75217       

Gene 3D

2.70.170.10     3.40.1280.10    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

Q5MPC5   H9JSB6   Q1HPQ6   I4DLF7   A0A2H1W7F8   A0A2H1WUS1   + More
A0A437BB50   A0A212EPD4   A0A3S2NHC8   A0A3S2LZB7   A0A2A4JFQ7   A0A212F1T1   A0A2A4JE90   A0A194RAB5   A0A194R9C5   A0A437BB20   A0A212EHP9   I4DLF6   A0A194PUL8   A0A437BB81   A0A3S2TB84   A0A437BWN7   A0A194PLU8   G9F9H9   G9F9H7   A0A2A4JQ23   A0A2W1B5H2   H9IWW2   A0A212F1E7   A0A2H1VIS4   I4DMI4   A0A194Q611   A0A194RM65   Q5MGE5   I4DQ94   A0A0N0PBX6   E0V917   A0A067RX29   Q9XY63   A0A1J1J158   A0A437BB41   A0A182LU74   A0A0L0CNX7   A0A182H431   A0A1I8NBH8   A0A1S4FI15   T1H2V5   A0A194RAY6   Q16ZZ9   A0A1Y9HF60   A0A084VW05   A0A182XWS6   A0A0A1WIS9   A0A0T6B1X0   A0A3S2NY81   E0VUP7   A0A1I8NXE1   A0A182QVG9   A0A182GA96   A0A182VY34   A0A182JNP3   A0A1I8NXF4   A0A1I8NXE7   A0A1I8NXD9   A0A1Q3FR28   X1WIF2   J9HYX9   Q170A0   A0A1Q3FRL8   A0A1V1FKN1   B0XFN4   A0A182U5J8   D6W6R5   A0A2J7RDN5   A0A0M8ZW49   A0A182X8T1   A0A1V1G565   A0A182UYI4   A0A1B0CS99   A0A1W4WXU4   Q9Y1K5   A0A2J7RDN0   A0A023EMY9   A0A182L6V0   Q7QAC0   A0A2M4AP36   B4N9Y9  

PDB

2OLG     E-value=5.86232e-35,     Score=369

KEGG

105841561    no KO assigned | (RefSeq) serine protease snake-like

GO

GO:0004252   GO:0008236   GO:0016021   GO:0005230   GO:0004888   GO:0008168   GO:0031638   GO:0009950   GO:0045752   GO:0006508   GO:0005488   GO:0003676   GO:0006281   GO:0043140   GO:0006310   GO:0000049   GO:0005975   GO:0004553  

PANTHER

PTHR18945   PTHR12636  

SignalP

Position:   1 - 18,         Likelihood:  0.992172

 

 

Length:

381

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.47517

Exp number, first 60 AAs:

0.16747

Total prob of N-in:

0.01424

outside

1  -  381

 

 

Pi

221.248186

Theta

27.814043

Tajima's D

-1.304486

CLR

14.402791

CSRT

0.0875456227188641

Interpretation

Uncertain