Gene

KWMTBOMO12405  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012427

Annotation

serine_protease_7_precursor_[Bombyx_mori]

Location

Bomo_Chr21(-):2378170-2386776      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.652

CDS

ATGGCGGTTACATCGTTATTGAGACTGGAAGTATTGTTTGCAATAACCTTTTGCATCGTGGCCGAAGTGTTAATGCACCCAGAAAACGACGCACTGCAAGGTTCTAGTGATAACAACTCTGATGGAAATAAACGGCCAGAAGAAATATGGTCTTGGGGCTATGTGGACAATACAAAATCCAACAACCAGTCTGCAACCACCGAAGAACCTGAAGTGTGCAAACCGTATAATCCAACAGTACCCAACTTCGAGAAACCTGGAAGAAGAATCAGTGAAGTCAAATGCTATGAATATCTATGGAATATAAATTTCAGAGAAGAGCGTGATCGAAGATTGGACAAATGCTTTAAGCTGCATAGTAATGTCCAGCCATCATTTGCTATTGGGGGACGTAACACATTACCTGGCGAATTTCCACACATGGGTGCCATAGGCTGGCAGGCAGTCGTTGGATCCTGGATATTCAAATGTGGTGGATCGTTGATTAGCAATAAATTTATACTGACTGCGGCTCATTGTACGAGCTTCTCCCTGAAAGACACTACCATCGCTGATCCTATTCCTAAGATCGTCAGACTCGGCGACAAATATATTTTAGACAAGGAAGTAAACGATGGCATAATCCCTGAAGATAGAGAGATCGTAAATATCATTAAACATCCATCCTACAATCCTCCGAAGAAATACTACGACATTGCCCTCATGGAGTTAGACAAAGATGTCTTCTTCAGCAAGTACGTGCAGCCGGCATGCCTTTGGCCTCACTTCGATCTCAGCAGTTTGGGGAAAAAAGCTAGTGCGACAGGATGGGGAGTTGTCGATGCAAGAAGCACTGACATATCGCCCGAACTGCAAGCTATCGTAATAGATTTGATAGATACCCCGCAATGTCAGCAATTGCTCGAGACTTCGTGCAACAGACACTGGTGCGGTGTCGAAGATCATCAGCTGTGCGCTGGGAAGTTGGCTGGGGGAGTGGATGCATGTCAGGGTGACTCTGGAGGTCCTCTCCAAGTTGAAATATCTCTTCCTACATCGTCTCAAGGCAAGATATATTGTATAATCGGCGTGACGTCATTCGGGATCGGCTGTGCTCTCCCTGAACTGCCCGGGATATACACGAGAGTGTCGAGCTTCATTGATTGGATCGAACAGAATGTTTGGCCTACAGTCCACCAAAGTGGTACAGCTTAG

Protein

MAVTSLLRLEVLFAITFCIVAEVLMHPENDALQGSSDNNSDGNKRPEEIWSWGYVDNTKSNNQSATTEEPEVCKPYNPTVPNFEKPGRRISEVKCYEYLWNINFREERDRRLDKCFKLHSNVQPSFAIGGRNTLPGEFPHMGAIGWQAVVGSWIFKCGGSLISNKFILTAAHCTSFSLKDTTIADPIPKIVRLGDKYILDKEVNDGIIPEDREIVNIIKHPSYNPPKKYYDIALMELDKDVFFSKYVQPACLWPHFDLSSLGKKASATGWGVVDARSTDISPELQAIVIDLIDTPQCQQLLETSCNRHWCGVEDHQLCAGKLAGGVDACQGDSGGPLQVEISLPTSSQGKIYCIIGVTSFGIGCALPELPGIYTRVSSFIDWIEQNVWPTVHQSGTA

Similarity

Belongs to the peptidase S1 family.
Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

H9JSB6   Q1HPQ6   Q5MPC5   A0A2H1W7F8   I4DLF7   A0A3S2NHC8   + More
A0A437BB50   A0A212F1T1   A0A212EPD4   A0A2H1WUS1   A0A3S2LZB7   A0A2A4JE90   A0A194RAB5   A0A437BB20   A0A2A4JFQ7   A0A212EHP9   A0A194R9C5   I4DLF6   A0A437BB81   A0A194PUL8   A0A437BWN7   A0A194PLU8   A0A2A4JQ23   A0A2W1B5H2   I4DMI4   A0A2H1VIS4   G9F9H9   A0A437BB41   I4DQ94   A0A212F1E7   A0A194RM65   A0A0N0PBX6   E0V917   A0A084VW05   Q9XY63   A0A1J1J158   A0A067RX29   A0A0N1PHM7   A0A1S4FI15   Q16ZZ9   A0A1Y1KAU3   A0A1Y9HED1   A0A182JGW6   A0A023EQX6   A0A2J7RDN5   A0A2C9GS29   A0A023EPR9   F5HLC4   A0A084W6V6   A0A2J7RDN0   Q170A0   A0A182ID15   A0A182VFE5   A0A182X8T2   J9HYX9   X1WIF2   A0A182LU74   A0A182U5J8   A0A1J1J052   A0A154P3Y1  

Pubmed

19121390    15944088    22651552    22118469    26354079    28756777    + More
20566863    24438588    24845553    17510324    28004739    24945155    12364791    14747013    17210077   

EMBL

BABH01033742    DQ443346    ABF51435.1    AY672785    AAV91007.1    ODYU01006800    + More
SOQ48987.1    AK402125    BAM18747.1    RSAL01000098    RVE47611.1    RVE47614.1    AGBW02010816    OWR47692.1    AGBW02013495    OWR43336.1    ODYU01011151    SOQ56716.1    RVE47596.1    NWSH01001694    PCG70405.1    KQ460473    KPJ14444.1    RVE47617.1    PCG70404.1    AGBW02014853    OWR40990.1    KPJ14443.1    AK402124    BAM18746.1    RVE47613.1    KQ459591    KPI97101.1    RSAL01000002    RVE54897.1    KQ459600    KPI94302.1    NWSH01000865    PCG73808.1    KZ150313    PZC71449.1    AK402502    BAM19124.1    ODYU01002797    SOQ40740.1    JN033724    AEW46877.1    RVE47618.1    AK403997    BAM20084.1    AGBW02010907    OWR47533.1    KQ459995    KPJ18524.1    KQ460736    KPJ12593.1    DS234988    EEB09873.1    ATLV01017365    KE525164    KFB42149.1    AF053921    AAD21841.1    CVRI01000064    CRL05174.1    KK852411    KDR24454.1    KQ458725    KPJ05344.1    CH477477    EAT40291.1    GEZM01092351    JAV56586.1    GAPW01002075    JAC11523.1    NEVH01005287    PNF38945.1    APCN01003246    GAPW01002076    JAC11522.1    AAAB01008888    EGK97085.1    ATLV01020986    KE525311    KFB45950.1    PNF38947.1    EAT40292.1    APCN01004968    CH477450    EJY57695.1    ABLF02031950    ABLF02031955    AXCM01003236    CRL05180.1    KQ434803    KZC05938.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000218220    UP000053240    UP000053268    + More
UP000009046    UP000030765    UP000183832    UP000027135    UP000008820    UP000075900    UP000075880    UP000235965    UP000075840    UP000007062    UP000075903    UP000076407    UP000007819    UP000075883    UP000075902    UP000076502   

PRIDE

H9JSB6    Q1HPQ6   

Pfam

PF00089   Trypsin        + More
PF02932   Neur_chan_memb
PF02931   Neur_chan_LBD
PF12032   CLIP
PF03587   EMG1
PF03226   Yippee-Mis18

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR001314   Peptidase_S1A       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR033116   TRYPSIN_SER       
IPR006029   Neurotrans-gated_channel_TM       
IPR006202   Neur_chan_lig-bd       
IPR036734   Neur_chan_lig-bd_sf       
IPR036719   Neuro-gated_channel_TM_sf       
IPR018000   Neurotransmitter_ion_chnl_CS       
IPR006201   Neur_channel       
IPR022700   CLIP       
IPR005304   Rbsml_bgen_MeTrfase_EMG1/NEP1       
IPR029028   Alpha/beta_knot_MTases       
IPR029026   tRNA_m1G_MTases_N       
IPR034750   CULT       
IPR015947   PUA-like_sf       
IPR003111   Lon_substr-bd       
IPR004910   Yippee/Mis18/Cereblon       

SUPFAM

SSF50494   SSF50494        + More
SSF90112   SSF90112       
SSF63712   SSF63712       
SSF75217   SSF75217       
SSF88697   SSF88697       

Gene 3D

2.70.170.10     3.40.1280.10    

CDD

cd00190  Tryp_SPc
cd15777  CRBN_C_like

ProteinModelPortal

H9JSB6   Q1HPQ6   Q5MPC5   A0A2H1W7F8   I4DLF7   A0A3S2NHC8   + More
A0A437BB50   A0A212F1T1   A0A212EPD4   A0A2H1WUS1   A0A3S2LZB7   A0A2A4JE90   A0A194RAB5   A0A437BB20   A0A2A4JFQ7   A0A212EHP9   A0A194R9C5   I4DLF6   A0A437BB81   A0A194PUL8   A0A437BWN7   A0A194PLU8   A0A2A4JQ23   A0A2W1B5H2   I4DMI4   A0A2H1VIS4   G9F9H9   A0A437BB41   I4DQ94   A0A212F1E7   A0A194RM65   A0A0N0PBX6   E0V917   A0A084VW05   Q9XY63   A0A1J1J158   A0A067RX29   A0A0N1PHM7   A0A1S4FI15   Q16ZZ9   A0A1Y1KAU3   A0A1Y9HED1   A0A182JGW6   A0A023EQX6   A0A2J7RDN5   A0A2C9GS29   A0A023EPR9   F5HLC4   A0A084W6V6   A0A2J7RDN0   Q170A0   A0A182ID15   A0A182VFE5   A0A182X8T2   J9HYX9   X1WIF2   A0A182LU74   A0A182U5J8   A0A1J1J052   A0A154P3Y1  

PDB

3W94     E-value=4.60294e-31,     Score=336

KEGG

733125    no KO assigned | (RefSeq) serine protease 7

GO

GO:0004252   GO:0008236   GO:0016021   GO:0005230   GO:0004888   GO:0008168   GO:0046872   GO:0006508   GO:0005488   GO:0003676   GO:0006281   GO:0043140   GO:0006310   GO:0000049   GO:0005975   GO:0004553  

PANTHER

PTHR18945   PTHR12636  

SignalP

Position:   1 - 21,         Likelihood:  0.716077

 

 

Length:

397

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

4.93716

Exp number, first 60 AAs:

4.33947

Total prob of N-in:

0.21952

outside

1  -  397

 

 

Pi

265.902205

Theta

150.517313

Tajima's D

0.439725

CLR

1.194053

CSRT

0.503774811259437

Interpretation

Uncertain