Gene

KWMTBOMO12386  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014084

Annotation

PREDICTED:_myotubularin-related_protein_10-A_[Bombyx_mori]

Location

Bomo_Chr21(-):1813648-1842776      View in EpiBrowser

Full name

Galactose-1-phosphate uridylyltransferase      

Location in the cell

Nuclear   Reliability : 1.05

CDS

ATGAATGAGAAGAAATTAGTGCAAAACTTCAAAAGCTACATCAACGTGTCGTCGAGCAAAGAAGAAAAGAATGGCACTATTCAAGAGGTGAAACCGAAATTATTGACAGGAGAGTTGGTGACTGGTGTAGCTCATAATGTGGTGATGCTGACTCCGCTTAGCGAGAGGGATCATGGTCGCTTGGGATCCGTCTTCGTTACAAACTACAAACTTTCATTCGTACCTTTGGAACGATCTCAACAGGATGAATGCAGTCAGCGGAACCACCTCCTCGGACCTCACGATGTGCCTTTATTGGCTGTGGGTGCAGTGTGGCTCACCGATGGCGGCCCGGTGCGGCGGCGAAGGCTCATGCCCTGCGGCGATATGCCCGGAAAGGTTAAAGGGCTCCAGATAATATGTAAGAATATGAAAGTAATAACGTTTAGTTTCACGACCGCCCCAATGCACAGCGGCAGGAAGATTGCCCTATCCCTAATGCACCACGCGTTCCCGAAGCGGCACCATCTATTGTTCGCCTTCGAATACCATGAGCCGTATTATCCGACTTTGCCGTCCGAACTGAACATGTTCCAAAGGCCGGGCGACTGGAAGCGTGAACTGGAACGATGCGAATGTCCCCACTGGCGGATAACCTGCATCAACGGCACGTCGGACGCCTTCATGCTGACCGCCGGTGAAACGCTGATAGTTCCGAATTCGGTCCTGGATTACAACCTGGTGGAGTCTGCGCGACACTTCAGGTCGGGTCGCGTGCCGGTGTGGGTGTGGGGCAGGCCGGAGGGCGCGGCGCTGCTGAGGAGCGGGGAGCTACTCCCCACAGAGCAGGCACCCACCGCCGAAAGCGTCTTATTAGAACAGATCCGACGTTCCCATCCAAAGCTGACACCTCCGCAAGTCCTATATCTGTGCGGGAACAGCTTCACCACTACTGGTTCGAACGCTAACATTCTACCTCCGCTCAGCAGTCTGCAGGCGTCTTTCAAGAAACTGATGGATCTCTGTACCCCTACGAAGTTGTCAGGGTTTTGGGTGCAGGACGCGCAGTACCACTCGGTGCTGGAGTCCAGCAAGTGGCTGCGGCACGTAGCCACGTGCCTGGCGCTGGCGGACGAGGCGGCACACCACCTGGCCCGCAACGTCACCGTCGTGCTGCAGGAAGGCGAGGGTGTGGACTACAGCGCGGTGGTGTCGAGCCTGACGCAGCTGCTGCTGGAGCCGCACTGGCGCACGCTGGTCGGCTTCCAGTCGCTCGTGCAGAAGGAGTGGCTGGCGCTCGGACACCCCTTCTGCGACCGGTACGGCCTCCCCAGTCCCGGCAACCCCAAGGAGACCCGGGAGCAGAGCCCGGGCCAGGTGGCGCCGGTGTTCCTGCTGTTCCTGGACTGCACGTGGCAGCTCACGCGGCAGTTCCCGGCCAGCTTCCAGTTCACGGAGACCTACCTCACCACGCTGTGGGACTGCACGCACAACCAGATATTCGACACCTTCCTGTTCAACTGTTCCCGGGACAGGGAACTTGCCTATACGAATAAGAAAAACCAGCAGAGCTTCGTCCCGGTGTGGGATTGGGGGGAGCAGTTCTCGGAGCAAGACAAGGCCCTGTTCTACAACCCGCTCTACGCGATGTCGGCCAAGCCTTCCAACGTCACTCCAAACAGATCCTCAATAATTTCGTCGCCGAACAAACAAGCCGTCGAGCTGCCGCGACTAGAACCCTGCACTTCGGTAGCGGGCACCGAGCTGTGGTCGCAGTGCTACGAGCGCTGGCTGCTGCCGCTCGACGTGCCGCACGCCGGCGACGTGCAGTACCACGTGTTTCACTACGCCGTGCTCAAGGAGATACAGCAGTTGAACGAGAAGCTGAACTCGCTGTCGATATTCTCAAACAGACAGTCGTTGGGCGGCAGCTCGGCGTCCGGCGCGGAGGGGCCCGGGGACCGCACCGCCGTGTCGCGGTTCTACCCGTTCAGTCGGTCGCGGGGCCCCGCCGCGCCCGCGCTCGACGCCATGCAGCTCAGCGCCATCGACGCCGCCTCGCTGCTCGACTCGCTGTCGCTACTGAACGCGCCGGACTAG

Protein

MNEKKLVQNFKSYINVSSSKEEKNGTIQEVKPKLLTGELVTGVAHNVVMLTPLSERDHGRLGSVFVTNYKLSFVPLERSQQDECSQRNHLLGPHDVPLLAVGAVWLTDGGPVRRRRLMPCGDMPGKVKGLQIICKNMKVITFSFTTAPMHSGRKIALSLMHHAFPKRHHLLFAFEYHEPYYPTLPSELNMFQRPGDWKRELERCECPHWRITCINGTSDAFMLTAGETLIVPNSVLDYNLVESARHFRSGRVPVWVWGRPEGAALLRSGELLPTEQAPTAESVLLEQIRRSHPKLTPPQVLYLCGNSFTTTGSNANILPPLSSLQASFKKLMDLCTPTKLSGFWVQDAQYHSVLESSKWLRHVATCLALADEAAHHLARNVTVVLQEGEGVDYSAVVSSLTQLLLEPHWRTLVGFQSLVQKEWLALGHPFCDRYGLPSPGNPKETREQSPGQVAPVFLLFLDCTWQLTRQFPASFQFTETYLTTLWDCTHNQIFDTFLFNCSRDRELAYTNKKNQQSFVPVWDWGEQFSEQDKALFYNPLYAMSAKPSNVTPNRSSIISSPNKQAVELPRLEPCTSVAGTELWSQCYERWLLPLDVPHAGDVQYHVFHYAVLKEIQQLNEKLNSLSIFSNRQSLGGSSASGAEGPGDRTAVSRFYPFSRSRGPAAPALDAMQLSAIDAASLLDSLSLLNAPD

Catalytic Activity

alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose

Similarity

Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Belongs to the PI3/PI4-kinase family.

Uniprot

A0A2W1BSK2   A0A2H1VQ45   A0A2A4JJG0   A0A194PUK2   A0A3S2TFP8   A0A1E1VZ49   + More
A0A212EZD7   A0A194RA04   A0A1B6FET7   A0A067QF58   A0A2J7QZ23   D6W9C8   A0A1B6DHH1   A0A1B6ECB3   A0A1B6CHL4   A0A1W4WVS2   A0A151X0E2   F4W893   A0A154PAP9   A0A195CD10   A0A158NSP7   A0A151HYU5   A0A195EWV1   A0A195DV19   A0A232FA20   A0A310S8W7   A0A026WXJ7   A0A0L7R0Q5   E2BET5   A0A087ZQU4   E2AKW2   A0A023F3V6   U4UB35   K7IWC7   N6U8I1   A0A224XKB0   T1I602   A0A1Y1LLW6   A0A0A9Y877   X1WM06   A0A2H8TIQ7   A0A2R7WEX6   A0A2S2PZ38   A0A0M8ZY64   U5ESQ6   A0A336MEF9   A0A2S2PAR2   A0A182I0W3   A0A182KJX2   A0A1S4H4G3   A0A182V4Y5   A0A146LK04   A0A1Q3G1C6   Q7Q0L7   A0A182JS99   A0A182N8W3   A0A182QGP7   A0A084W5L7   Q16UR7   A0A182RAE7   A0A0K8TME0   A0A0T6B751   T1IWR3   A0A1B0D6B3   A0A182MTC7   A0A2M4AEY2   A0A182IVB5   A0A182YN08   A0A2M4CIG7   A0A182PPU5   A0A1Q3G182   A0A2M4BG68   A0A2M4BGE5   A0A182F8V6   A0A1S3I2K1   A0A1S3I2C1   A0A182VSS7   A0A1B0CTU6   A0A182GHK0   A0A1S3I242   A0A0P5GNF6   A0A0P5D015   A0A0P5JMQ2   A0A0P6CK84   E9GXW4   A0A0N8BSB1   A0A0N8C6Z7   A0A0P5J2Y3   A0A0P6AEK7   A0A0P5IHT5   A0A0P5LDJ0   A0A0P5J5A7   A0A0P5PPZ0   A0A0N8BWB1   A0A0P5TM47   A0A0N8C7T5  

EC Number

2.7.7.12

Pubmed

28756777    26354079    22118469    24845553    18362917    19820115    + More
21719571    21347285    28648823    24508170    30249741    20798317    25474469    23537049    20075255    28004739    25401762    20966253    12364791    26823975    24438588    17510324    26369729    25244985    26483478    21292972   

EMBL

KZ149932    PZC77311.1    ODYU01003766    SOQ42940.1    NWSH01001364    PCG71540.1    + More
KQ459591    KPI97086.1    RSAL01000188    RVE44753.1    GDQN01011047    JAT80007.1    AGBW02011326    OWR46821.1    KQ460473    KPJ14462.1    GECZ01031774    GECZ01023126    GECZ01021047    GECZ01018585    JAS37995.1    JAS46643.1    JAS48722.1    JAS51184.1    KK853714    KDQ94596.1    NEVH01009080    PNF33833.1    KQ971312    EEZ98180.1    GEDC01012162    JAS25136.1    GEDC01001726    JAS35572.1    GEDC01024418    JAS12880.1    KQ982624    KYQ53700.1    GL887898    EGI69588.1    KQ434857    KZC08887.1    KQ978023    KYM97968.1    ADTU01025098    KQ976723    KYM76662.1    KQ981948    KYN32631.1    KQ980322    KYN16592.1    NNAY01000634    OXU27288.1    KQ769812    OAD52831.1    KK107078    QOIP01000011    EZA60466.1    RLU17134.1    KQ414670    KOC64423.1    GL447857    EFN85801.1    GL440425    EFN65879.1    GBBI01003098    JAC15614.1    KB631924    ERL87170.1    APGK01044424    KB741026    ENN74907.1    GFTR01007536    JAW08890.1    ACPB03008319    ACPB03008320    GEZM01054918    JAV73340.1    GBHO01016470    GBHO01016451    GBHO01015231    GBHO01015230    GBRD01000365    JAG27134.1    JAG27153.1    JAG28373.1    JAG28374.1    JAG65456.1    ABLF02017485    ABLF02017488    ABLF02017494    ABLF02017495    GFXV01001353    MBW13158.1    KK854564    PTY16915.1    GGMS01000969    MBY70172.1    KQ435826    KOX72003.1    GANO01003125    JAB56746.1    UFQS01000781    UFQT01000781    SSX06838.1    SSX27183.1    GGMR01013916    MBY26535.1    APCN01005279    AAAB01008980    GDHC01011859    GDHC01007099    JAQ06770.1    JAQ11530.1    GFDL01001489    JAV33556.1    EAA14220.4    AXCN02001867    ATLV01020673    KE525304    KFB45511.1    CH477615    EAT38271.1    GDAI01002297    JAI15306.1    LJIG01009646    KRT82663.1    JH431629    AJVK01025887    AJVK01025888    AXCM01000163    GGFK01006002    MBW39323.1    GGFL01000972    MBW65150.1    GFDL01001480    JAV33565.1    GGFJ01002891    MBW52032.1    GGFJ01002890    MBW52031.1    AJWK01027997    JXUM01064037    JXUM01064038    KQ562279    KXJ76245.1    GDIQ01245424    JAK06301.1    GDIP01164532    JAJ58870.1    GDIQ01196494    JAK55231.1    GDIQ01090085    JAN04652.1    GL732573    EFX75743.1    GDIQ01149771    JAL01955.1    GDIQ01108683    JAL43043.1    GDIQ01230224    JAK21501.1    GDIP01030794    JAM72921.1    GDIQ01214578    JAK37147.1    GDIQ01172646    JAK79079.1    GDIQ01206841    JAK44884.1    GDIQ01168506    GDIQ01155061    GDIQ01126065    LRGB01002451    JAL25661.1    KZS07465.1    GDIQ01138571    JAL13155.1    GDIP01125792    JAL77922.1    GDIQ01106379    JAL45347.1   

Proteomes

UP000218220    UP000053268    UP000283053    UP000007151    UP000053240    UP000027135    + More
UP000235965    UP000007266    UP000192223    UP000075809    UP000007755    UP000076502    UP000078542    UP000005205    UP000078540    UP000078541    UP000078492    UP000215335    UP000053097    UP000279307    UP000053825    UP000008237    UP000005203    UP000000311    UP000030742    UP000002358    UP000019118    UP000015103    UP000007819    UP000053105    UP000075840    UP000075882    UP000075903    UP000007062    UP000075881    UP000075884    UP000075886    UP000030765    UP000008820    UP000075900    UP000092462    UP000075883    UP000075880    UP000076408    UP000075885    UP000069272    UP000085678    UP000075920    UP000092461    UP000069940    UP000249989    UP000000305    UP000076858   

Pfam

PF06602   Myotub-related        + More
PF12578   3-PAP
PF14969   DUF4508
PF02744   GalP_UDP_tr_C
PF01087   GalP_UDP_transf
PF00226   DnaJ
PF09320   DUF1977
PF00792   PI3K_C2
PF00613   PI3Ka
PF00454   PI3_PI4_kinase

Interpro

IPR029021   Prot-tyrosine_phosphatase-like        + More
IPR030564   Myotubularin_fam       
IPR010569   Myotubularin-like_Pase_dom       
IPR022587   MTMR12-like_C       
IPR011993   PH-like_dom_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR028019   DUF4508       
IPR001937   GalP_UDPtransf1       
IPR019779   GalP_UDPtransf1_His-AS       
IPR005849   GalP_Utransf_N       
IPR036265   HIT-like_sf       
IPR005850   GalP_Utransf_C       
IPR036940   PI3/4_kinase_cat_sf       
IPR015399   DUF1977_DnaJ-like       
IPR036869   J_dom_sf       
IPR015433   PI_Kinase       
IPR016024   ARM-type_fold       
IPR035892   C2_domain_sf       
IPR001263   PI3K_accessory_dom       
IPR042236   PI3K_accessory_sf       
IPR002420   PI3K_C2_dom       
IPR000403   PI3/4_kinase_cat_dom       
IPR018936   PI3/4_kinase_CS       
IPR011009   Kinase-like_dom_sf       
IPR001623   DnaJ_domain       

SUPFAM

SSF52799   SSF52799        + More
SSF48452   SSF48452       
SSF54197   SSF54197       
SSF46565   SSF46565       
SSF48371   SSF48371       
SSF56112   SSF56112       

Gene 3D

2.30.29.30     1.25.40.10     3.30.428.10     1.10.1070.11     1.10.287.110     1.25.40.70     2.60.40.150    

CDD

cd00608  GalT
cd06257  DnaJ

ProteinModelPortal

A0A2W1BSK2   A0A2H1VQ45   A0A2A4JJG0   A0A194PUK2   A0A3S2TFP8   A0A1E1VZ49   + More
A0A212EZD7   A0A194RA04   A0A1B6FET7   A0A067QF58   A0A2J7QZ23   D6W9C8   A0A1B6DHH1   A0A1B6ECB3   A0A1B6CHL4   A0A1W4WVS2   A0A151X0E2   F4W893   A0A154PAP9   A0A195CD10   A0A158NSP7   A0A151HYU5   A0A195EWV1   A0A195DV19   A0A232FA20   A0A310S8W7   A0A026WXJ7   A0A0L7R0Q5   E2BET5   A0A087ZQU4   E2AKW2   A0A023F3V6   U4UB35   K7IWC7   N6U8I1   A0A224XKB0   T1I602   A0A1Y1LLW6   A0A0A9Y877   X1WM06   A0A2H8TIQ7   A0A2R7WEX6   A0A2S2PZ38   A0A0M8ZY64   U5ESQ6   A0A336MEF9   A0A2S2PAR2   A0A182I0W3   A0A182KJX2   A0A1S4H4G3   A0A182V4Y5   A0A146LK04   A0A1Q3G1C6   Q7Q0L7   A0A182JS99   A0A182N8W3   A0A182QGP7   A0A084W5L7   Q16UR7   A0A182RAE7   A0A0K8TME0   A0A0T6B751   T1IWR3   A0A1B0D6B3   A0A182MTC7   A0A2M4AEY2   A0A182IVB5   A0A182YN08   A0A2M4CIG7   A0A182PPU5   A0A1Q3G182   A0A2M4BG68   A0A2M4BGE5   A0A182F8V6   A0A1S3I2K1   A0A1S3I2C1   A0A182VSS7   A0A1B0CTU6   A0A182GHK0   A0A1S3I242   A0A0P5GNF6   A0A0P5D015   A0A0P5JMQ2   A0A0P6CK84   E9GXW4   A0A0N8BSB1   A0A0N8C6Z7   A0A0P5J2Y3   A0A0P6AEK7   A0A0P5IHT5   A0A0P5LDJ0   A0A0P5J5A7   A0A0P5PPZ0   A0A0N8BWB1   A0A0P5TM47   A0A0N8C7T5  

PDB

5C16     E-value=7.72792e-39,     Score=405

KEGG

101738321    K18085 myotubularin-related protein 10/11/12 | (RefSeq) myotubularin-related protein 10-A

GO

GO:0033499   GO:0008108   GO:0008270   GO:0016301   GO:0016021   GO:0048015   GO:0046854   GO:0005524  

PANTHER

PTHR10807   PTHR11943   PTHR10048  

Length:

692

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0811099999999999

Exp number, first 60 AAs:

0.01611

Total prob of N-in:

0.00427

outside

1  -  692

 

 

Pi

207.762443

Theta

175.918078

Tajima's D

0.490541

CLR

0.19636

CSRT

0.508224588770561

Interpretation

Uncertain