Gene

KWMTBOMO12378  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012406

Annotation

PREDICTED:_mitochondrial_import_inner_membrane_translocase_subunit_TIM50-C-like_[Amyelois_transitella]

Location

Bomo_Chr21(+):1731957-1738052      View in EpiBrowser

Full name

Mitochondrial import inner membrane translocase subunit TIM50       + More
Mitochondrial import inner membrane translocase subunit TIM50-C      

Alternative Name

Tiny tim 50

Location in the cell

Cytoplasmic   Reliability : 1.83 Nuclear   Reliability : 1.808

CDS

ATGTATTTCAGGAAATTATTATTTCTGACAAAAACCGCGTGTTGTAAATCTTTAAAGCTAGAGACAAAATGCCACTCAAGACAAAACATTTGGATAATAGCAGCGAATTCGCCAAAATTTTATTCAAATCAAAATTTAGATGATAGAAGTAAAGATGATAAACCTGAAAAAGTAGATATCTTAGGGAGGTTCTTCCCGCAAGCCCCACAGACACAGGTTGATGCACAGCAGATTAAAAAAGAACAAGAACGTTTTGAGCAAGAAAACAAAGAGAAAACTGAAGAAAATGAAAAAAGTTGGAGAAGAATGAAATTAGGTTTTGCAGTTTTTGGTGGTGGTCTCACAGTAGCAGCGACCTGCCTTGTCATAGAGATGGGCTCACCCCGACGGGATGATGAGGGTCAAATAATAGAGGATGAATTTTCACATCTTCCCATTGTCTTTCAATACCTGAGACGTTCCTGGAAAGAACTCACATTTTATGAAAAGATGATAAAGGAGCCATCAAGAGAGAAATTACTTCCAGACCCTTTGCCTCCACCGTACCAGCCTACATACACTCTAGTCTTAGAATTCACAGATGTCCTGGTGCATCCTGATTGGTCTTACCAAACGGGCTGGAGGTTCAAGAAGCGGCCCGGCGTGGACCAGTTCCTCCAGGCGGTCGCGAGCTCTAATTACGAAATCGTCATCTTCACGACGGAGAACGCTATGATGATCTGGCCGGTGTTAGACAAACTAGACCCCGAGAACAAGTACATAACGCACCGTCTGTTCCGCGACTCCACGCACTTCGTCGACGGCGTGCACGTTAAGAACCTCGAGGGACTCAACAGGGACTTGTCGAAGGTTATCGTGGTCGATTGGAACAAGGCAGCAACCAAGTTCCACCCGCAGAACTCGCTGATCCTGAAGAAGTGGAAGGGAGCTGATGAAGACACGTCGCTGCTCGACCTGGCCAATCTGCTGCAGACGATAGCGATGTCGGAGGTGGCGGACGTGCGCGAGGTGCTGTCCTACTACGGACAGTTCGAGGACCCCATCGCAGCCTTCCGGGACAACCAGCGCCGCCTCATGGAGCAGCTCGAGGAGCGGGAGAAGGCTCCCAAGCAGGACAACACGCTCACCAGGAGCTGGCTGCGGACCTTCACCAGGCGCTAG

Protein

MYFRKLLFLTKTACCKSLKLETKCHSRQNIWIIAANSPKFYSNQNLDDRSKDDKPEKVDILGRFFPQAPQTQVDAQQIKKEQERFEQENKEKTEENEKSWRRMKLGFAVFGGGLTVAATCLVIEMGSPRRDDEGQIIEDEFSHLPIVFQYLRRSWKELTFYEKMIKEPSREKLLPDPLPPPYQPTYTLVLEFTDVLVHPDWSYQTGWRFKKRPGVDQFLQAVASSNYEIVIFTTENAMMIWPVLDKLDPENKYITHRLFRDSTHFVDGVHVKNLEGLNRDLSKVIVVDWNKAATKFHPQNSLILKKWKGADEDTSLLDLANLLQTIAMSEVADVREVLSYYGQFEDPIAAFRDNQRRLMEQLEEREKAPKQDNTLTRSWLRTFTRR

Description

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

Subunit

Component of the TIM23 complex.
Component of the TIM23 complex at least composed of Tim23, Tim17 (Tim17a1, Tim17a2 or Tim17b1) and a Tim50.

Similarity

Belongs to the TIM50 family.

Keywords

Complete proteome   Membrane   Mitochondrion   Mitochondrion inner membrane   Protein transport   Reference proteome   Transit peptide   Translocation   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Mitochondrial import inner membrane translocase subunit TIM50-C

Uniprot

A0A2W1BQE2   A0A2A4K7A1   A0A2H1WSQ7   A0A437BG93   A0A194PWE6   A0A212EZ98   + More
A0A194R9E9   D3TQJ3   A0A0L0C1V7   A0A1Q3F3I7   A0A2J7R809   A0A2J7R7Z8   A0A1B0FNI7   A0A2J7R7Z6   B4Q0W2   B0W954   A0A182MKL0   A0A3B0JXY0   Q177F9   A0A1I8Q899   A0A0S0X8K7   Q9W4V8   A0A182VWA7   U5EVH6   A0A182R538   A0A182GPX6   E2ARS3   B4JXL4   T1P7Q9   A0A1I8NG44   E0VRI5   A0A182IJ55   A0A026W2G9   A0A2M4AIT1   A0A0M3QZ79   A0A182Q6J6   B4M3R7   A0A182UFQ0   A0A182K8J3   A0A182FRX1   A0A069DYS9   A0A182NR28   A0A182PR45   A0A195DX70   A0A0P4VTB3   R4FP27   A0A182UNA5   A0A182SSL7   A0A182XNW4   A0A154PG67   B4L390   W5J744   A0A182HK12   E2C935   A0A0V0G8C3   A0A182L887   Q7PWY2   A0A195B9H1   D6WUM7   B4NDV4   A0A151X667   A0A2A3EU14   A0A088AJ70  

Pubmed

28756777    26354079    22118469    20353571    26108605    17994087    + More
17550304    17510324    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    10731137    12537569    26483478    20798317    25315136    20566863    24508170    30249741    26334808    27129103    20920257    23761445    20966253    12364791    14747013    17210077    18362917    19820115   

EMBL

KZ149932    PZC77302.1    NWSH01000093    PCG79643.1    ODYU01010780    SOQ56093.1    + More
RSAL01000066    RVE49390.1    KQ459591    KPI97079.1    AGBW02011326    OWR46826.1    KQ460473    KPJ14468.1    EZ423695    ADD19971.1    JRES01001001    KNC26242.1    GFDL01012956    JAV22089.1    NEVH01006723    PNF36956.1    PNF36955.1    CCAG010006847    PNF36957.1    CM000162    EDX01329.1    DS231862    EDS39751.1    AXCM01009825    OUUW01000011    SPP86914.1    CH477376    EAT42318.1    AE014298    ALI51141.1    AL021728    AY070535    GANO01003403    JAB56468.1    JXUM01079199    KQ563113    KXJ74443.1    GL442166    EFN63881.1    CH916376    EDV95113.1    KA644552    AFP59181.1    DS235478    EEB15991.1    KK107499    QOIP01000003    EZA49791.1    RLU25292.1    GGFK01007362    MBW40683.1    CP012528    ALC48919.1    AXCN02001481    CH940651    EDW65442.1    GBGD01001860    JAC87029.1    KQ980155    KYN17478.1    GDKW01001378    JAI55217.1    ACPB03008304    GAHY01001069    JAA76441.1    KQ434899    KZC10849.1    CH933810    EDW07018.1    ADMH02002129    ETN58604.1    APCN01000813    GL453779    EFN75544.1    GECL01002112    JAP04012.1    AAAB01008987    EAA01623.5    KQ976542    KYM81183.1    KQ971357    EFA08496.1    CH964239    EDW81923.1    KQ982482    KYQ55895.1    KZ288185    PBC34994.1   

Proteomes

UP000218220    UP000283053    UP000053268    UP000007151    UP000053240    UP000037069    + More
UP000235965    UP000092444    UP000002282    UP000002320    UP000075883    UP000268350    UP000008820    UP000095300    UP000000803    UP000075920    UP000075900    UP000069940    UP000249989    UP000000311    UP000001070    UP000095301    UP000009046    UP000075880    UP000053097    UP000279307    UP000092553    UP000075886    UP000008792    UP000075902    UP000075881    UP000069272    UP000075884    UP000075885    UP000078492    UP000015103    UP000075903    UP000075901    UP000076407    UP000076502    UP000009192    UP000000673    UP000075840    UP000008237    UP000075882    UP000007062    UP000078540    UP000007266    UP000007798    UP000075809    UP000242457    UP000005203   

PRIDE

Q9W4V8    A0A088AJ70   

Pfam

PF03031   NIF

Interpro

IPR027111   Tim50        + More
IPR036412   HAD-like_sf       
IPR023214   HAD_sf       
IPR004274   FCP1_dom       
IPR036859   CAP-Gly_dom_sf       

SUPFAM

SSF56784   SSF56784        + More
SSF74924   SSF74924       

Gene 3D

3.40.50.1000    

ProteinModelPortal

A0A2W1BQE2   A0A2A4K7A1   A0A2H1WSQ7   A0A437BG93   A0A194PWE6   A0A212EZ98   + More
A0A194R9E9   D3TQJ3   A0A0L0C1V7   A0A1Q3F3I7   A0A2J7R809   A0A2J7R7Z8   A0A1B0FNI7   A0A2J7R7Z6   B4Q0W2   B0W954   A0A182MKL0   A0A3B0JXY0   Q177F9   A0A1I8Q899   A0A0S0X8K7   Q9W4V8   A0A182VWA7   U5EVH6   A0A182R538   A0A182GPX6   E2ARS3   B4JXL4   T1P7Q9   A0A1I8NG44   E0VRI5   A0A182IJ55   A0A026W2G9   A0A2M4AIT1   A0A0M3QZ79   A0A182Q6J6   B4M3R7   A0A182UFQ0   A0A182K8J3   A0A182FRX1   A0A069DYS9   A0A182NR28   A0A182PR45   A0A195DX70   A0A0P4VTB3   R4FP27   A0A182UNA5   A0A182SSL7   A0A182XNW4   A0A154PG67   B4L390   W5J744   A0A182HK12   E2C935   A0A0V0G8C3   A0A182L887   Q7PWY2   A0A195B9H1   D6WUM7   B4NDV4   A0A151X667   A0A2A3EU14   A0A088AJ70  

PDB

3QLE     E-value=1.4252e-26,     Score=297

KEGG

101738982    K17496 mitochondrial import inner membrane translocase subunit TIM50 | (RefSeq) mitochondrial import

GO

GO:0016021   GO:0005744   GO:0015031   GO:0007005   GO:0016787   GO:0007006   GO:0005739   GO:0004722   GO:0005743   GO:0006470   GO:0004725   GO:0030150   GO:0004721  

PANTHER

PTHR12210:SF3  

Subcellular location

Mitochondrion inner membrane  

Length:

386

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

13.56834

Exp number, first 60 AAs:

0.00017

Total prob of N-in:

0.58984

outside

1  -  386

 

 

Pi

167.227164

Theta

167.08828

Tajima's D

-0.509209

CLR

130.693282

CSRT

0.23788810559472

Interpretation

Uncertain