SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO12374  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA012400
Annotation
hypothetical_protein_TcasGA2_TC032179_[Tribolium_castaneum]
Location
Bomo_Chr21(+):1661637-1687771      View in EpiBrowser
Location in the cell
Cytoplasmic   Reliability : 2.478
 

Sequence

CDS
ATGGCCACAGATAACCTAACCGCTTTGTTGTACAAACCAAATGATTTGCGTTTGGTACAAACACCGATCCCTGAAATATCTGAAGATGAGGTCCTGCTGCGCATGGACTGCGTGGGTATCTGCGGGTCAGACGTCCACTACTGGCAGAAGGGTCAATGCGGACACTTCGTGCTGGAAGAACCAATGATCATGGGACACGAAGCTTCAGGAGTAGTGGCCAAGATCGGTTCGAAAGTCAAGAATCTGACAGTTGGTGATCGAGTGGCCATAGAGCCCGGCGTGCCGTGTCGGTACTGCGAGTTCTGTAAGACAGGACGATACCACCTATGCCCTGACATGATCTTCTGCGCCACGCCCCCAGTACACGGAAACCTCGTCAGATATTACAAGCACGCAGCTGATTTTTGCTTCAAGCTTCCTGATCACGTGACCATGGAAGAAGGAGCGCTACTGGAGCCCCTCGCGGTGGGCATTCACGCGTGCAAGAGGGGCGGAGTCTCGGCGGGACACGTGGTGCTGGTACTGGGAGCGGGACCCATCGGCCTCCTTACCATGCTCACAGCTAAAGCCTTTGGAGCACACAAAGTACTCATAATAGATATCCTTCAGAGCCGTTTGGATTTCGCCAAGTCGTTAGGCGCCGACTACACACTTCTCATAGGCAAGGACTCGAACGAGGCTGAGCTGGTGAGGAAGATTCATGAGATACTGGAGGGACACCCCGACGTGTCGTTCGATGCGAGTGGGGCCCAGGCCACAGTCAGATTAGCGTTACTGGCCACGAAGTCTGGCGGCGTGGCGGTGCTGGTCGGCATGGGAGCGCCCGAGCAGACCGTGCCGCTCGCGGGCGCCCTCTCGCGGGAGGTCGACATCCGGGGCATCTTCCGATACGTCAACGACTACCCCACTGCACTAGCGATGGTAGCGAGTGGGAAAATAAACGTGAAGCCGCTGGTCACGCACCACTTCAGCATCGAGGAGAGCCTGGAGGCGTACGAAGTGGCGCGCCAGGGGGCCGGCATCAAGCCAGATGATAAATTGAGTATTTTAATTCGGGCCACCGTGCTCAGCGTAAAACCAAGAGTGTCAGTGAGATCTCACGCGTCCGACATGGCCACAGATAACATAACCGCTTTATTGTACAAAACAAATGATTTGCGTTTGGTACAAACACCGATCCCTGAAATATCTGATAACGAGGTCCTGCTGCGTATGGACTGCGTGGGTATCTGCGGGTCAGACATCCAATACTGGCAGAAGGGTCAATGCGGACACTTCGTGCTGCAAAAACCAATGATCATGGGACACGAAGCTTCAGGAGTAGTGGCTAAGATCGGTTCAAAAGTCAAGAATCTGACAGTTGGTGATCGAGTGGCCATAGAGCCCGGCGTGCCGTGTCGGTACTGCGAGTTCTGTAAGACAGGACGGTACCACCTATGCCCCGACATGATCTTCTGCGCCACGCCCCCAGTACACGGAAACCTCGTCAGATATTACAAGCACGCAGCCGATTTTTGCTTCAAGCTTCCTGATCACGTGACCATGGAAGAAGGAGCGCTACTGGAGCCCCTCGCGGTGGGCATTCACGCGTGCAAGAGGGGCGGAGTCTCGGCGGGACACGTGGTGCTGGTACTGGGAGCGGGACCCATCGGCCTCCTTACCATGCTCACAGCTAAAGCCTTTGGAGCACACAAAGTACTCATAATAGATATTCTTCAGAGCCGTTTGGATTTCGCCAAGTCGTTAGGCGCCGACTACACACTTCTCATAGGCAAGGACTCGAACGAGGCTGAGCTGGTGAGGAAGATTCATGCGCTACTGGAGGGACATCCTGACGTGTCGTTCGACGTGAGTGGGGCCCAGACCACCATCAGATTAGCATTGCTGGCCACGAAGTCTGGCGGCGTGGCGGTGCTGGTCGGCATGGGAGCGCCCGAGCAGACCGTGCCGCTCGCGGGCGCCCTCTCGCGGGAGGTCGACATCCGGGGCATCTTCCGATACGTTAACGACTACCCCACTGCACTAGCGATGGTAGCGAGTGGGAAAATAAACGTGAAGCCGCTGGTCACCCACCACTTCAGCATCGAGGAGAGCCTGGAGGCGTACGAAGTGGCGCGCCAGGGGGCCGGCATCAAGGTCATGATCCACGTCCAGCCGCGAGACACAAACAACCCACAAAAGTTCTGA
Protein
MATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELVRKIHEILEGHPDVSFDASGAQATVRLALLATKSGGVAVLVGMGAPEQTVPLAGALSREVDIRGIFRYVNDYPTALAMVASGKINVKPLVTHHFSIEESLEAYEVARQGAGIKPDDKLSILIRATVLSVKPRVSVRSHASDMATDNITALLYKTNDLRLVQTPIPEISDNEVLLRMDCVGICGSDIQYWQKGQCGHFVLQKPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSLGADYTLLIGKDSNEAELVRKIHALLEGHPDVSFDVSGAQTTIRLALLATKSGGVAVLVGMGAPEQTVPLAGALSREVDIRGIFRYVNDYPTALAMVASGKINVKPLVTHHFSIEESLEAYEVARQGAGIKVMIHVQPRDTNNPQKF

Summary

Cofactor
Zn(2+)
Similarity
Belongs to the zinc-containing alcohol dehydrogenase family.
Uniprot
A0A139WNA4   A0A1I8H9M0   A0A182MHV2   A0A1I8HMA2   A0A182P938   A0A182Y7D2   + More
A0A182F7A7   A0A183UNY7   A0A182K6B9   A0A182N4S1   A0A182VHL9   A0A3S3MQV2   A0A0B0PQI9   A0A2S4V6D4   A0A183F5H1   A0A3P7TF07  
Pubmed
18362917    19820115    26392545    25244985    30626928   
EMBL
KQ971312    KYB29291.1    AXCM01001020    UYWY01020425    VDM41528.1    QPKB01000003    + More
RWR80724.1    KN439958    KHG27122.1    PKSL01000103    POW05089.1    UZAH01001540    VDO19796.1   
Proteomes
UP000007266    UP000095280    UP000075883    UP000075885    UP000076408    UP000069272    + More
UP000050794    UP000267007    UP000075881    UP000075884    UP000075903    UP000283530    UP000239156    UP000050761   
Pfam
PF08240   ADH_N        + More
PF00107   ADH_zinc_N
Interpro
IPR036291   NAD(P)-bd_dom_sf        + More
IPR020843   PKS_ER       
IPR011032   GroES-like_sf       
IPR013149   ADH_C       
IPR002328   ADH_Zn_CS       
IPR013154   ADH_N       
IPR013083   Znf_RING/FYVE/PHD       
IPR001965   Znf_PHD       
IPR011011   Znf_FYVE_PHD       
IPR001841   Znf_RING       
IPR042013   PHF7/G2E3_ePHD       
IPR034732   EPHD       
SUPFAM
SSF50129   SSF50129        + More
SSF51735   SSF51735       
SSF57903   SSF57903       
Gene 3D
3.30.40.10    
CDD
cd15669  ePHD_PHF7_G2E3_like
ProteinModelPortal
A0A139WNA4   A0A1I8H9M0   A0A182MHV2   A0A1I8HMA2   A0A182P938   A0A182Y7D2   + More
A0A182F7A7   A0A183UNY7   A0A182K6B9   A0A182N4S1   A0A182VHL9   A0A3S3MQV2   A0A0B0PQI9   A0A2S4V6D4   A0A183F5H1   A0A3P7TF07  
PDB
1E3J     E-value=8.7268e-114,     Score=1052

Ontologies

KEGG
100529206    K00008 L-iditol 2-dehydrogenase [EC:1.1.1.14] | (RefSeq) SDH2b; sorbitol dehydrogenase-2b
PATHWAY
00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00051    Fructose and mannose metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
GO
GO:0016491   GO:0008270   GO:0016021   GO:0046872   GO:0006468   GO:0006811   GO:0005524   GO:0003909   GO:0051103   GO:0000049   GO:0005975   GO:0004553   GO:0055114  

Topology

Length:
728
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
15.1884
Exp number, first 60 AAs:
0.00041
Total prob of N-in:
0.41386
outside
1  -  728
 
 

Population Genetic Test Statistics

Pi
159.539373
Theta
156.449108
Tajima's D
-1.042967
CLR
16.014039
CSRT
0.132693365331733
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
28556443 HAADFCFK 100.00 4e-10
28556443 HAADFCFK 100.00 4e-10
26822097 ATDNITAIIYKPNDIR 95.83 6e-10
26280517 GPQIFHMDPSGTFVQYDAK 95.83 6e-10
27102218 ATDNITAIIYKPNDIR 95.83 6e-10
28556443 YHSFYPWHAGGDYR 100.00 7e-10
28556443 YHSFYPWHAGGDYR 100.00 7e-10
26822097 IHEIIEGHPDVSFDASGAQATVR 95.83 1e-09
26280517 KIGFTGSTPIGQTIMK 95.83 1e-09
28556443 DSNEAELVR 100.00 2e-09
26822097 GQCGHFVIEEPMIMGHEASGVVAK 95.65 6e-09
26280517 IGVMEDPSNR 95.65 6e-09
26822097 IVQTPIPEISEDEVIIR 100.00 3e-07
26280517 KSEVITNVVNK 100.00 3e-07
28467696 MDASPPVR 100.00 3e-07
28556443 VLIIDILQSR 100.00 1e-06
28556443 VLIIDILQSR 100.00 1e-06
28556443 IHEILEGHPDVSFDASGAQATVR 100.00 7e-05
28556443 LVQTPIPEISEDEVLLR 100.00 8e-05
28556443 ATDNLTALLYKPNDLR 100.00 8e-05
28556443 LPDHVTMEEGALLEPLAVGIHACK 100.00 8e-05
28556443 VLIIDILQSR 100.00 2e-04
28556443 VLIIDILQSR 100.00 2e-04
28556443 YHLCPDMIFCATPPVHG 100.00 2e-04
28556443 YHLCPDMIFCATPPVHG 100.00 2e-04
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