Gene

KWMTBOMO12368

Pre Gene Modal

BGIBMGA012368

Annotation

PREDICTED:_bumetanide-sensitive_sodium-(potassium)-chloride_cotransporter_[Bombyx_mori]

Location

Bomo_Chr21(-):1554083-1575786      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.655

CDS

ATGTTCGTATACTTGTCTACAGTGGAGGTGCTGTGGCAGAACATGGGCCCCGACTACAGATATTACGAGGGCGTCCATCACAACTTCTTCTCGGTATTCTCCATATTCTTCCCGGCCGCTACCGGGATATTAGCCGGCGCCAACATTTCGGGAGATTTGAAGGACCCTCAGAAGTCGATTCCGAAGGGCACGCTGCTCGCCATCCTGCTGACGACGCTGTCGTACCTGCTGATAGCGGTGGTGTCGGGCTGGTCGGTGCTGCGGGACGCGTCGGGGGACGTGGCCGACCTGGCCGCCGGCTCGCTGGCCGCCTGCGTCCATAACGGTACCTGCGCGTACGGTCTGCAGAACGACTACCATGTGGTGCGGCTGGTGTCAGCCTTCGGTCCACTCATTCACGGAGGTTGCTTCGCGGCCGCGCTCTCCTCCGCGCTGGCCTCTCTGGTCTCCGCTCCGAAGGTCTTCCAGGCGCTGTGTCAGGACAAGCTGTACCCCTATATCGAGTTCTTCGCTAAGGGCTACGGACCCAACAACGAGCCCGTGCGAGGGTACGTGCTGACCTTCGTCATCGCCACCACCTTCATACTCCTGGGCGGCCTGAACCAGATAGCCCCGCTGATATCGAACTTCTTCCTGGCGGCCTACACGCTCATCAACTTCTCCACGTTCCACGCGAGCCTCGCCAGGCCCGTCGGCTGGAGACCCACCTTCAGGTTTTACAACATGTGGCTGTCGCTGCTGGGCTCGGTGCTGTGCGTGGTCATCATGTTCGTGGTGTCGTGGAGCCAGGCGCTCGGCACCTTCGCCTTCCTGCTCGCCCTCTACCTGCTCGTGTCCTACAGGAAGCCAGACGTGAACTGGGGCTCCACGACGCAGGCGCAGACGTACAAGACGGCGCTGGCCGGCGTGCAGCTGCTCAACGGGATCGACGAGCACGTCAAGAACTACAGGCCGCAAGTCCTGGTGCTGACGGGGTTCCCGGGGGAGCGGCCGCTGCTCACGGACTTCACGTACCTGCTGACCAAGGGACTGTCGCTGATGCTGTGCGGACAGATCGTTCAAGGTCCGGTGAGCCAGCCGACGCGCGAGGCCCTCAGCAAGCGAGCGTACGGCTGGTTCCAGCGCCGGAAGATCAAGGCCTTCTACACCCTGGTCGATGACGTCAGCTTCAAGGACGGCGCCAGCGCGCTGGTGCAGAGCAGCGGGCTCGGGAAGCTCACCCCCAACATCCTCATGATGGGCTTCAAGCAGGACTGGCGCACGTGCAGCAGGCAACACCTGGTGGACTACGTCGAGGTCATGCATAAAGCGTTGGACGTGCACATGGCGCTCGCGATACTGCGCATCGAGGGCGGACAGTACAGCAGCGAGGCGCTCGACGAAGACCTCCAGATCTACCTCAATGACCTCAACGCTAACGGCGTGGCGGGAATATCGCGTTCCATGGGAGATACATACAAAGCAACGAAGTCTACGGAGAGCCTCAACACTCAGTCCGAAGGCAGCACGTCTGACTTGTCGGTGGGGTCGCCACAGCTGCGACGCGCCGTCTCGCAGGACCCCGGCGCAGACCCGGACAAGGAGCAAGTCAAAATTAAAAAAAGCGGCAAAGGAAGTAAAGGTCTAAGTTACGCTGTGCGGAGGGCTCTAGGGTCTGCGGTGGCTCGCAGGGCGTCCTCGTTCACTTCAGTGGAACAATTCACGAGGAGGCAGGCCGGGACCGTCGACGTTTGGTGGCTCTATGACGACGGAGGTCTGACCCTGTTGCTGCCGTACATCCTGTCCACCAGACGCGCCTGGTCTTCCAGCCCGCTGCGGATATTCACGCTCGCCAACAAGAACACGGAGCTGGAGATCGAAGAAAGGAACATGGCGTCCCTGCTGTCCAAGTTCCGCATCGACTACTCGGCGCTGACGGTGGTGGCGGACATCACGCGGCGCCCCCGGGACTCCACGCTGGACTACTTCGACCAGCTCATCGCGCCCTTCATGGTGCCGGAAGACGCCAACCATACGGCGGGTGTGACGGCGGGAGTGACTGCGGGCGACCTGGCGGCGGCCCGCGAGCGCACGCACCGGCACCTGCGGCTGCGCGAGCTCATCGGGGAGCGGTCCCGGGGCGCGCGGCTGGTGTGCGCCACGCTGCCCATGCCGCGCCGCCGCAGCGTGGTGCCGCCGCCGCTCTACGCCGCCTGGCTGCACGCCATCGCCTCCGCCGCCGACAACACGCTGCTCGTGCGCGGCAACCACGAGCCCGTGCTCACCTTCTACTCCTGA

Protein

MFVYLSTVEVLWQNMGPDYRYYEGVHHNFFSVFSIFFPAATGILAGANISGDLKDPQKSIPKGTLLAILLTTLSYLLIAVVSGWSVLRDASGDVADLAAGSLAACVHNGTCAYGLQNDYHVVRLVSAFGPLIHGGCFAAALSSALASLVSAPKVFQALCQDKLYPYIEFFAKGYGPNNEPVRGYVLTFVIATTFILLGGLNQIAPLISNFFLAAYTLINFSTFHASLARPVGWRPTFRFYNMWLSLLGSVLCVVIMFVVSWSQALGTFAFLLALYLLVSYRKPDVNWGSTTQAQTYKTALAGVQLLNGIDEHVKNYRPQVLVLTGFPGERPLLTDFTYLLTKGLSLMLCGQIVQGPVSQPTREALSKRAYGWFQRRKIKAFYTLVDDVSFKDGASALVQSSGLGKLTPNILMMGFKQDWRTCSRQHLVDYVEVMHKALDVHMALAILRIEGGQYSSEALDEDLQIYLNDLNANGVAGISRSMGDTYKATKSTESLNTQSEGSTSDLSVGSPQLRRAVSQDPGADPDKEQVKIKKSGKGSKGLSYAVRRALGSAVARRASSFTSVEQFTRRQAGTVDVWWLYDDGGLTLLLPYILSTRRAWSSSPLRIFTLANKNTELEIEERNMASLLSKFRIDYSALTVVADITRRPRDSTLDYFDQLIAPFMVPEDANHTAGVTAGVTAGDLAAARERTHRHLRLRELIGERSRGARLVCATLPMPRRRSVVPPPLYAAWLHAIASAADNTLLVRGNHEPVLTFYS

Uniprot

H9JS58   A0A2W1BUF7   A0A2A4K7K6   A0A212F8J7   A0A2J7Q344   A0A0L0BWL3   + More
A0A067QZ58   W8AQQ8   T1PLE3   T1PCU7   A0A1I8MNN3   W8B4Z9   A0A034V8A2   A0A034V5K0   B4J334   A0A0P8YFC8   A0A0K8WGP6   A0A0P8XSH9   B3M7T3   A0A1A9WEC2   B4L068   A0A182K428   A0A182N5V8   Q8T5I9   B4QR94   A0A0J9RVB7   A0A182TW57   A0A1I8NN16   A0A1I8NN17   A0A182HL76   A0A1W4WT68   A0A3B0JZA7   A0A1S4GCA3   Q9VTW8   A0A182WSC5   A0A3B0K266   A0A182QW38   B4PGC5   A0A1W4WH00   A0A0A9WLJ8   A0A3B0JZD4   A0A182V675   A0A182IUZ5   A0A0K8THF8   A0A0Q9WQ97   A0A0J9RUA0   B3NH95   B4LFG0   A0A182R4U3   Q2M0N5   A0A2M4CSC4   A0A2M3YYV0   A0A0R3P7S7   W5JDN1   A0A0R1DXN2   A0A2M4CSL5   A0A2M4BB00   M9PCA7   A0A182PGT7   A0A1W4UGX5   A0A2M3ZY80   A0A2M4BCB9   D2A527   A0A2M4CSF9   A0A2M3ZYG8   A0A182FBN2   A0A182MPU2   A0A0Q5U446   A0A1W4UU50   A0A182VWK0   A0A154PG76   A0A182YAE0   A0A0Q9WVL2   A0A0J9RU03   A0A1Q3FV52   A0A1Q3FYY0   A0A182GFY2   A0A0R1E2A3   A0A1B6CXS0   A0A1B6D1J5   A0A1B6D5F3   A0A0M4ELI8   B4N3I8   A0A195FZH4   A0A182L9J3   A0A1B6KU44   A0A1Y1L619   A0A195DRW0   A0A0L7R055   A0A195BTY2   A0A1B6I7U9   A0A1B6K8B8   A0A026WBV0   A0A158NVA6   A0A1B6K518   A0A0J9UJU1   M9PI37   A0A0R1DXU5   A0A0Q5UIZ1   A0A151WUM5  

Pubmed

19121390    28756777    22118469    26108605    24845553    24495485    + More
25315136    25348373    17994087    18057021    12060762    12364791    14747013    17210077    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25401762    26823975    15632085    20920257    23761445    18362917    19820115    25244985    26483478    20966253    28004739    24508170    21347285   

EMBL

BABH01033155    BABH01033156    BABH01033157    BABH01033158    KZ149932    PZC77295.1    + More
NWSH01000093    PCG79632.1    AGBW02009708    OWR50064.1    NEVH01019070    PNF23008.1    JRES01001238    KNC24410.1    KK853171    KDR10326.1    GAMC01018178    JAB88377.1    KA649571    AFP64200.1    KA646607    AFP61236.1    GAMC01018179    JAB88376.1    GAKP01021184    JAC37768.1    GAKP01021183    JAC37769.1    CH916366    EDV96105.1    CH902618    KPU77647.1    GDHF01023471    GDHF01018967    GDHF01010956    GDHF01001988    JAI28843.1    JAI33347.1    JAI41358.1    JAI50326.1    KPU77645.1    EDV38806.1    KPU77646.1    CH933809    EDW18014.2    AJ439353    AAAB01008987    CAD27923.1    EAA00828.4    CM000363    EDX10224.1    CM002912    KMY99219.1    APCN01000883    OUUW01000012    SPP87415.1    AE014296    AY094735    AAF49927.1    AAM11088.1    AAS65014.1    SPP87413.1    AXCN02001150    CM000159    EDW94289.1    GBHO01037874    GBHO01006440    GBHO01006439    GDHC01017468    JAG05730.1    JAG37164.1    JAG37165.1    JAQ01161.1    SPP87414.1    GBRD01000867    JAG64954.1    CH940647    KRF84279.1    KMY99217.1    CH954178    EDV51552.1    EDW69258.1    CH379069    EAL30895.2    GGFL01004078    MBW68256.1    GGFM01000684    MBW21435.1    KRT07741.1    ADMH02001683    ETN61443.1    KRK01749.1    GGFL01004077    MBW68255.1    GGFJ01001059    MBW50200.1    AGB94449.1    AGB94450.1    AGB94452.1    GGFK01000205    MBW33526.1    GGFJ01001558    MBW50699.1    KQ971361    EFA05305.2    GGFL01004079    MBW68257.1    GGFK01000189    MBW33510.1    AXCM01001708    KQS43848.1    KQ434889    KZC10308.1    KRF84277.1    KRF84278.1    KRF84280.1    KMY99218.1    GFDL01003571    JAV31474.1    GFDL01002302    JAV32743.1    JXUM01010846    JXUM01010847    JXUM01010848    JXUM01010849    KQ560318    KXJ83080.1    KRK01746.1    GEDC01019031    JAS18267.1    GEDC01017805    JAS19493.1    GEDC01016379    JAS20919.1    CP012525    ALC44322.1    CH964095    EDW79193.1    KQ981193    KYN45204.1    GEBQ01025056    JAT14921.1    GEZM01065969    JAV68258.1    KQ980530    KYN15608.1    KQ414672    KOC64235.1    KQ976417    KYM89879.1    GECU01024714    JAS82992.1    GECU01000014    JAT07693.1    KK107324    EZA52534.1    ADTU01027052    ADTU01027053    GECU01001443    JAT06264.1    KMY99220.1    AGB94451.1    KRK01743.1    KRK01745.1    KRK01747.1    KRK01748.1    KQS43847.1    KQ982745    KYQ51345.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000235965    UP000037069    UP000027135    + More
UP000095301    UP000001070    UP000007801    UP000091820    UP000009192    UP000075881    UP000075884    UP000007062    UP000000304    UP000075902    UP000095300    UP000075840    UP000192223    UP000268350    UP000000803    UP000076407    UP000075886    UP000002282    UP000075903    UP000075880    UP000008792    UP000008711    UP000075900    UP000001819    UP000000673    UP000075885    UP000192221    UP000007266    UP000069272    UP000075883    UP000075920    UP000076502    UP000076408    UP000069940    UP000249989    UP000092553    UP000007798    UP000078541    UP000075882    UP000078492    UP000053825    UP000078540    UP000053097    UP000005205    UP000075809   

PRIDE

H9JS58    Q9VTW8    M9PCA7    M9PI37   

Pfam

PF03522   SLC12        + More
PF00324   AA_permease
PF08403   AA_permease_N

Interpro

IPR004841   AA-permease/SLC12A_dom        + More
IPR018491   SLC12_C       
IPR013612   AA_permease_N       
IPR004842   SLC12A_fam       
IPR002443   SLC12A1/SLC12A2       

ProteinModelPortal

H9JS58   A0A2W1BUF7   A0A2A4K7K6   A0A212F8J7   A0A2J7Q344   A0A0L0BWL3   + More
A0A067QZ58   W8AQQ8   T1PLE3   T1PCU7   A0A1I8MNN3   W8B4Z9   A0A034V8A2   A0A034V5K0   B4J334   A0A0P8YFC8   A0A0K8WGP6   A0A0P8XSH9   B3M7T3   A0A1A9WEC2   B4L068   A0A182K428   A0A182N5V8   Q8T5I9   B4QR94   A0A0J9RVB7   A0A182TW57   A0A1I8NN16   A0A1I8NN17   A0A182HL76   A0A1W4WT68   A0A3B0JZA7   A0A1S4GCA3   Q9VTW8   A0A182WSC5   A0A3B0K266   A0A182QW38   B4PGC5   A0A1W4WH00   A0A0A9WLJ8   A0A3B0JZD4   A0A182V675   A0A182IUZ5   A0A0K8THF8   A0A0Q9WQ97   A0A0J9RUA0   B3NH95   B4LFG0   A0A182R4U3   Q2M0N5   A0A2M4CSC4   A0A2M3YYV0   A0A0R3P7S7   W5JDN1   A0A0R1DXN2   A0A2M4CSL5   A0A2M4BB00   M9PCA7   A0A182PGT7   A0A1W4UGX5   A0A2M3ZY80   A0A2M4BCB9   D2A527   A0A2M4CSF9   A0A2M3ZYG8   A0A182FBN2   A0A182MPU2   A0A0Q5U446   A0A1W4UU50   A0A182VWK0   A0A154PG76   A0A182YAE0   A0A0Q9WVL2   A0A0J9RU03   A0A1Q3FV52   A0A1Q3FYY0   A0A182GFY2   A0A0R1E2A3   A0A1B6CXS0   A0A1B6D1J5   A0A1B6D5F3   A0A0M4ELI8   B4N3I8   A0A195FZH4   A0A182L9J3   A0A1B6KU44   A0A1Y1L619   A0A195DRW0   A0A0L7R055   A0A195BTY2   A0A1B6I7U9   A0A1B6K8B8   A0A026WBV0   A0A158NVA6   A0A1B6K518   A0A0J9UJU1   M9PI37   A0A0R1DXU5   A0A0Q5UIZ1   A0A151WUM5  

KEGG

101737814    K10951 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | (RefSeq) bumetan

GO

GO:0006811   GO:0005215   GO:0016021   GO:0055085   GO:0015377   GO:0008511   GO:0005886   GO:0005623   GO:0015379   GO:0055078   GO:0035725   GO:1902476   GO:0015081   GO:0015378   GO:0055064   GO:0055075   GO:0006884   GO:1990573   GO:0015171   GO:0006813   GO:0003333   GO:0006821   GO:0006810   GO:0016020   GO:0005524   GO:0003909   GO:0051103   GO:0000049   GO:0005975   GO:0004553  

Length:

758

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

134.68864

Exp number, first 60 AAs:

22.50201

Total prob of N-in:

0.27644

POSSIBLE N-term signal

sequence

outside

1  -  28

TMhelix

29  -  51

inside

52  -  63

TMhelix

64  -  86

outside

87  -  126

TMhelix

127  -  149

inside

150  -  183

TMhelix

184  -  206

outside

207  -  209

TMhelix

210  -  232

inside

233  -  238

TMhelix

239  -  261

outside

262  -  758

 

 

Pi

329.151071

Theta

179.88979

Tajima's D

2.9042

CLR

0.769478

CSRT

0.975301234938253

Interpretation

Uncertain