Gene

KWMTBOMO12358

Annotation

PREDICTED:_uncharacterized_protein_LOC101741620_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr21(-):1061008-1063336      View in EpiBrowser

Full name

6-phosphogluconate dehydrogenase, decarboxylating       + More
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]      

Alternative Name

tRNA-dihydrouridine synthase 3

Location in the cell

Nuclear   Reliability : 4.501

CDS

ATGACAGAAATAGAAGACTTGATTTCGGAGGTGGAGAAAAATCCATGTCTATGGAACGTCGGTTGTAGTAATTATCAAAATAAAACGCAAAGGGACTTGGCCCGGGAAGAGATATGCAAAAGAATCATCCCACATTGGAATGATTTGAACATGGAAGATAAAAAGCAAATTAGGGAATATAAAAAGAAACAATGGAATAACGTCAGAGACGGTTACCGAAAATATTTGAACAGAAACAAAAATACGCCCGTGCCAAAGAAGAAATTCATTTACGAGAATGACCTTTATTTTTTGTTACCGGTTTTACAAAACAGCAAATCTCGCGAACGGAACATGCCATCGGAATTACACGAAGATAGTTACGAAGACAACGAAACTATTGAAATTGAAGTGAGACCACAAACGGAAGACGAGGATGACGAAGACGAGAGGAAACCGTTCAGAAAATACGCAACTTCAGAAAGACAGACTAAAGCTCAACAGAAATATACGCCCGACGAAATACCTTATCAAATTCTAAACATAACAAAACAGAATACGGACGATGAAGTCAGCTACCAAGATGTGGATTCTCAATTCCTGCTGAGCTTCCGAGACGACATGAATGCGATGTCGAGATCTCAGAAACTGAAATTCAAATTAGGCATGATCCAATTAATACAACACGTAACCGAAGATCGGGTCAGTGACCCCTTCGGTGAGTGTTGA

Protein

MTEIEDLISEVEKNPCLWNVGCSNYQNKTQRDLAREEICKRIIPHWNDLNMEDKKQIREYKKKQWNNVRDGYRKYLNRNKNTPVPKKKFIYENDLYFLLPVLQNSKSRERNMPSELHEDSYEDNETIEIEVRPQTEDEDDEDERKPFRKYATSERQTKAQQKYTPDEIPYQILNITKQNTDDEVSYQDVDSQFLLSFRDDMNAMSRSQKLKFKLGMIQLIQHVTEDRVSDPFGEC

Catalytic Activity

6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH

Cofactor

FMN

Similarity

Belongs to the 6-phosphogluconate dehydrogenase family.
Belongs to the dus family. Dus3 subfamily.

Uniprot

H9JS66   A0A3S2NHN2   H9J8Q4   A0A437B0K8   A0A2J7PBC8   A0A067RA73   + More
J9KU42   A0A2S2PS33   A0A2S2QKM5   A0A0N0BFW2   A0A1E1WMV5   A0A026WD33   X1X940   A0A310SQK1   A0A2H1WP32   A0A2A3ERT0   A0A088AEC2   A0A0J7L3L1   J9LWL6   J9KBQ0   A0A195DC77   H9IVN4   A0A151IFB9   A0A423T9B0   F4WMC5   A0A158P282   A0A195BR61   A0A195F3Q1   A0A151XC39   A0A0P4WIC9   E2AWC0   A0A0L7R227   A0A1B6HMR2   K7IX93   A0A3S2PHX9   A0A0T6BB68   B0W7G5   A0A3S2LQC0   A0A2P6KGP1   Q17I54   A0A444T9D1   J9EDY0   A0A3P7E1U8   A0A0R3R2M1   A0A1E1WLC3   A0A0H5S1L7   A0A212EVC2   A0A0N5D5I8   A0A1B6HMN4   A0A437BSU1   A0A2S2NEL4   A0A437BCD2   A0A3S2NB70   A0A2S2NVF4   A0A0N4TX01   A0A2S2P7V0   A0A0P4WGF5   Q16WX9   A0A146M773   A0A1B6HE62   A0A194QLR2   A0A1E1WHR4   A0A2W1BRZ0   A0A1B6MVI3   A0A0P4WQG1   A0A2J7R5Z7   A0A0N0PCI2   A0A0J7K819   A0A2A4K541   B3LXX9   J9KKF9   A0A194PPX0   A0A0T6B6I9   A0A1B6FZ56   A0A044V964   A0A3P6U100  

EC Number

1.1.1.44
1.3.1.-

Pubmed

19121390    24845553    24508170    30249741    21719571    21347285    + More
20798317    20075255    17510324    26850696    17885136    22118469    26823975    26354079    28756777    17994087   

EMBL

BABH01033119    RSAL01000035    RVE51328.1    BABH01030371    RSAL01000224    RVE43986.1    + More
NEVH01027118    NEVH01016302    NEVH01007440    PNF13628.1    PNF25815.1    PNF35690.1    KK852602    KDR20478.1    ABLF02030014    GGMR01019594    MBY32213.1    GGMS01009116    MBY78319.1    KQ435794    KOX73672.1    GDQN01002878    JAT88176.1    KK107261    QOIP01000012    EZA53972.1    RLU16330.1    ABLF02034356    KQ761662    OAD57183.1    ODYU01010020    SOQ54829.1    KZ288192    PBC34400.1    LBMM01000937    KMQ97188.1    ABLF02035814    ABLF02012823    KQ980989    KYN10515.1    BABH01039610    KQ977799    KYM99596.1    QCYY01002080    ROT73029.1    GL888217    EGI64769.1    ADTU01001164    KQ976418    KYM89451.1    KQ981855    KYN34807.1    KQ982315    KYQ57858.1    GDRN01070949    JAI63786.1    GL443280    EFN62280.1    KQ414666    KOC64878.1    GECU01031770    JAS75936.1    AAZX01000580    AAZX01000618    RSAL01000027    RVE51911.1    LJIG01002364    KRT84576.1    DS231854    EDS38000.1    RSAL01000501    RVE41524.1    MWRG01012481    PRD25477.1    CH477242    EAT46375.1    SAUD01040394    SAUD01007315    RXG51670.1    RXG62280.1    ADBV01004300    EJW80661.1    UYWW01001533    VDM10647.1    UZAG01019009    VDO41994.1    GDQN01003403    JAT87651.1    LN856534    CRZ22603.1    AGBW02012210    OWR45442.1    UYYF01004606    VDN05797.1    GECU01031767    JAS75939.1    RSAL01000012    RVE53523.1    GGMR01002773    MBY15392.1    RSAL01000092    RVE47958.1    RSAL01000288    RVE42933.1    GGMR01008582    MBY21201.1    UZAD01013389    VDN94591.1    GGMR01012912    MBY25531.1    GDRN01058001    JAI65639.1    CH477551    EAT39109.1    GDHC01004002    JAQ14627.1    GECU01034815    JAS72891.1    KQ461196    KPJ06467.1    GDQN01004532    JAT86522.1    KZ149960    PZC76385.1    GEBQ01000068    JAT39909.1    GDRN01070950    JAI63785.1    NEVH01006986    PNF36258.1    KQ460651    KPJ13045.1    LBMM01011903    KMQ86558.1    NWSH01000149    PCG79034.1    CH902617    EDV42835.1    ABLF02039726    ABLF02039730    ABLF02044102    KQ459596    KPI95362.1    LJIG01009493    KRT82969.1    GECZ01014282    JAS55487.1    CMVM020000255    UYRW01003313    VDK88653.1   

Proteomes

UP000005204    UP000283053    UP000235965    UP000027135    UP000007819    UP000053105    + More
UP000053097    UP000279307    UP000242457    UP000005203    UP000036403    UP000078492    UP000078542    UP000283509    UP000007755    UP000005205    UP000078540    UP000078541    UP000075809    UP000000311    UP000053825    UP000002358    UP000002320    UP000008820    UP000288706    UP000004810    UP000093561    UP000270924    UP000050602    UP000006672    UP000007151    UP000046394    UP000276776    UP000038020    UP000278627    UP000053240    UP000218220    UP000007801    UP000053268    UP000024404    UP000271087   

PRIDE

H9JS66    H9J8Q4    H9IVN4   

Pfam

PF10545   MADF_DNA_bdg        + More
PF02944   BESS
PF01093   Clusterin
PF13499   EF-hand_7
PF00393   6PGD
PF03446   NAD_binding_2
PF01207   Dus

Interpro

IPR039353   TF_Adf1        + More
IPR006578   MADF-dom       
IPR004210   BESS_motif       
IPR000753   Clusterin-like       
IPR011992   EF-hand-dom_pair       
IPR002048   EF_hand_dom       
IPR018247   EF_Hand_1_Ca_BS       
IPR006114   6PGDH_C       
IPR013328   6PGD_dom2       
IPR036291   NAD(P)-bd_dom_sf       
IPR008927   6-PGluconate_DH-like_C_sf       
IPR006183   Pgluconate_DH       
IPR006113   6PGDH_Gnd/GntZ       
IPR006115   6PGDH_NADP-bd       
IPR018517   tRNA_hU_synthase_CS       
IPR001269   tRNA_hU_synthase       
IPR035587   DUS-like_FMN-bd       
IPR013785   Aldolase_TIM       
IPR000571   Znf_CCCH       

SUPFAM

SSF47473   SSF47473        + More
SSF48179   SSF48179       
SSF51735   SSF51735       

Gene 3D

1.10.1040.10     3.20.20.70    

CDD

cd00051  EFh
cd02801  DUS_like_FMN

ProteinModelPortal

H9JS66   A0A3S2NHN2   H9J8Q4   A0A437B0K8   A0A2J7PBC8   A0A067RA73   + More
J9KU42   A0A2S2PS33   A0A2S2QKM5   A0A0N0BFW2   A0A1E1WMV5   A0A026WD33   X1X940   A0A310SQK1   A0A2H1WP32   A0A2A3ERT0   A0A088AEC2   A0A0J7L3L1   J9LWL6   J9KBQ0   A0A195DC77   H9IVN4   A0A151IFB9   A0A423T9B0   F4WMC5   A0A158P282   A0A195BR61   A0A195F3Q1   A0A151XC39   A0A0P4WIC9   E2AWC0   A0A0L7R227   A0A1B6HMR2   K7IX93   A0A3S2PHX9   A0A0T6BB68   B0W7G5   A0A3S2LQC0   A0A2P6KGP1   Q17I54   A0A444T9D1   J9EDY0   A0A3P7E1U8   A0A0R3R2M1   A0A1E1WLC3   A0A0H5S1L7   A0A212EVC2   A0A0N5D5I8   A0A1B6HMN4   A0A437BSU1   A0A2S2NEL4   A0A437BCD2   A0A3S2NB70   A0A2S2NVF4   A0A0N4TX01   A0A2S2P7V0   A0A0P4WGF5   Q16WX9   A0A146M773   A0A1B6HE62   A0A194QLR2   A0A1E1WHR4   A0A2W1BRZ0   A0A1B6MVI3   A0A0P4WQG1   A0A2J7R5Z7   A0A0N0PCI2   A0A0J7K819   A0A2A4K541   B3LXX9   J9KKF9   A0A194PPX0   A0A0T6B6I9   A0A1B6FZ56   A0A044V964   A0A3P6U100  

KEGG

101746616    no KO assigned | (RefSeq) uncharacterized LOC101746616

GO

GO:0003677   GO:0005634   GO:0005509   GO:0004616   GO:0050661   GO:0006098   GO:0019521   GO:0017150   GO:0050660   GO:0046872   GO:0032580   GO:0008270   GO:0005524   GO:0003909   GO:0051103   GO:0000049   GO:0005975   GO:0004553  

PANTHER

PTHR12243   PTHR11811  

Subcellular location

Nucleus  

Length:

235

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02600

outside

1  -  235

 

 

Pi

168.593668

Theta

164.534285

Tajima's D

0.134736

CLR

1.372576

CSRT

0.404129793510324

Interpretation

Uncertain