SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO12346  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA012380
Annotation
mitochondrial_inorganic_phosphate_carrier_[Bombyx_mori]
Full name
Phosphate carrier protein, mitochondrial      
Alternative Name
Phosphate transport protein
Solute carrier family 25 member 3
Location in the cell
Mitochondrial   Reliability : 1.309 PlasmaMembrane   Reliability : 1.776
 

Sequence

CDS
ATGTCGAAGAAGCCCAAAGAAGAGTTCTCTTGTGAGATGTACAGCAACAAATACTTCATGCTGTGCGCTTACGGAGGCGCCTGTGCTTGCGGGATCACGCATACCTTCGTTACACCTCTGGACTTGGTCAAGTGCCGCCTGCAAGTTGACCCGGCCAAATACAAATCCATATTTAAAGGATTCGGGATATCTATCAAAGAAGGCGGCGCTGCTAACCTCGTAAAAGGCTGGGCACCTACGCTCATAGGCTATTCTATGCAAGGTTCGTCAAAATTTGCTGGCTACGAATACTTCAAGTACAAATTCTCCAAAATGGTTGATGAAGAATCGGCGTACTTATACAGAACTTACCTGTATTTAGCTGCTGCAGCATCGGCCGAATGCATAGCTGATATCTTCCTTTCTCCTTTCGAAGCCACTAAAGTCCGGATACAAACAACGCCGGGGTACACGTCAAAGATGCGGAAGGCCATGCCACATATGCTGGCCACAGAAGGCTTTGGAGTCTTTTACCGTGGCTTAGTGCCGTTATGGGGGCGACAAATTCCCTACACTATGATGAAATTCGCGTCTTTCGAGAAAACACTTGAGTACTTGTATGAGAATGTTGTGCCCAAGCCTCGTGACCAGTGCACCAAGATTGAGCAGCTCCTCGTTACGTTCACAGCTGGGTACATAGCTGGGGTGCTGTGCGCTATAGTGTCGCATCCAGCTGACACGATCGTTTCCAAGCTCAATAAGGACCCCGGGGCTTCGATCGGGGGTATCATAGCCGAAGTGGGGCCGATGGGCATCTGGCGAGGTCTAGTGGCTCGCATCATTATGATTGGCACCCTCACAGGACTGCAATGGTTTATTTATGACGGTTTCAAAGTGAAAATGGGTATGCCTCGGCCGCCTCCCGCAGAGATGCCAGAATCCCTTAGAAAGAAACTGGCGGCAAAGAAGTAA
Protein
MSKKPKEEFSCEMYSNKYFMLCAYGGACACGITHTFVTPLDLVKCRLQVDPAKYKSIFKGFGISIKEGGAANLVKGWAPTLIGYSMQGSSKFAGYEYFKYKFSKMVDEESAYLYRTYLYLAAAASAECIADIFLSPFEATKVRIQTTPGYTSKMRKAMPHMLATEGFGVFYRGLVPLWGRQIPYTMMKFASFEKTLEYLYENVVPKPRDQCTKIEQLLVTFTAGYIAGVLCAIVSHPADTIVSKLNKDPGASIGGIIAEVGPMGIWRGLVARIIMIGTLTGLQWFIYDGFKVKMGMPRPPPAEMPESLRKKLAAKK

Summary

Description
Transport of phosphate groups from the cytosol to mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP) (By similarity).
Subunit
Interacts with PPIF; the interaction is impaired by CsA.
Similarity
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Keywords
Acetylation   Complete proteome   Direct protein sequencing   Membrane   Methylation   Mitochondrion   Mitochondrion inner membrane   Phosphoprotein   Reference proteome   Repeat   Symport   Transit peptide   Transmembrane   Transmembrane helix   Transport  
Feature
chain  Phosphate carrier protein, mitochondrial
EMBL
BABH01033078    LC185244    BAX57167.1    DQ443259    ABF51348.1    JTDY01004977    + More
KOB67521.1    KQ460473    KPJ14495.1    KQ459591    KPI97049.1    AGBW02009347    OWR51045.1    NWSH01001051    PCG72916.1    KZ149941    PZC76910.1    LC185248    BAX57171.1    ODYU01011814    SOQ57773.1    LC185246    BAX57169.1    GAIX01011964    JAA80596.1    KQ459580    KPI99185.1    AGBW02012340    OWR45188.1    NWSH01002045    PCG69317.1    AK402569    BAM19191.1    GDQN01011329    JAT79725.1    RSAL01000072    RVE49066.1    GEZM01047428    JAV76842.1    LC185247    BAX57170.1    KQ459603    KPI92775.1    CVRI01000057    CRL02082.1    KT163645    AKN21595.1    IACF01000192    LAB65995.1    DQ443390    LC185243    ABF51479.1    BAX57166.1    CH933809    EDW19503.1    KE346365    KJE93245.1    MDVM02000098    PYZ99293.1    QCYY01002018    ROT73569.1    KQ414785    KOC60988.1    ATLV01013150    KE524842    KFB37339.1    FR904298    CDQ58193.1    FR906594    CDQ84906.1    AFYH01015166    GGFK01001122    MBW34443.1    GDRN01016809    JAI67835.1    CR855322    CU207255    UYSU01041945    VDM03468.1    AK077274    AK077723    AK088013    AK150641    AK150729    AK150870    AK151518    AK152006    AK152292    AK152341    AK167197    AK168580    BC018161    AK168129    BAE40098.1    AK151088    BAE30101.1    AK151887    BAE30772.1    GEEE01023912    JAP39313.1    CM004471    OCT87577.1    APCN01005530    LC185245    BAX57168.1    BT058623    BT060336    ACN10336.1    ACN12696.1    LC185260    BAX57183.1    LC185261    BAX57184.1    GAMD01003047    JAA98543.1    KK854006    PTY09131.1    GAMD01003222    JAA98368.1    AAAB01008888    EAA08862.4    AXCM01001020    KQ982543    KYQ55387.1    CH940647    EDW70218.1    AEYP01012179    AEYP01012180    KFB37338.1    DS235016    EEB10504.1    GDJX01026659    JAT41277.1    EGK97073.1    UYRU01050590    VDN11060.1    KQ980414    KYN16144.1    CH479183    EDW36132.1    GFDL01000354    JAV34691.1    BC067565    AAH67565.1    GBXM01010200    JAH98377.1    CM000071    EAL25707.1    GL888295    EGI63001.1    BC046849    CM004470    AAH46849.1    OCT88795.1    KQ981440    KYN41663.1    BT074720    ACO09144.1    OUUW01000001    SPP72930.1    GCES01056981    JAR29342.1    KK107364    QOIP01000007    EZA51918.1    RLU20419.1   
Pfam
PF00153   Mito_carr        + More
PF02893   GRAM
Interpro
IPR018108   Mitochondrial_sb/sol_carrier        + More
IPR023395   Mt_carrier_dom_sf       
IPR004182   GRAM       
IPR002067   Mit_carrier       
SUPFAM
SSF103506   SSF103506       
Gene 3D
PDB
2LCK     E-value=0.0120232,     Score=90

Ontologies

Topology

Subcellular location
Mitochondrion inner membrane  
Length:
316
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
88.12316
Exp number, first 60 AAs:
18.55735
Total prob of N-in:
0.87156
POSSIBLE N-term signal
sequence
inside
1  -  215
TMhelix
216  -  238
outside
239  -  263
TMhelix
264  -  286
inside
287  -  316
 
 

Population Genetic Test Statistics

Pi
184.301381
Theta
195.13622
Tajima's D
-0.432806
CLR
0.016045
CSRT
0.254037298135093
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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