Gene

KWMTBOMO12346  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012380

Annotation

mitochondrial_inorganic_phosphate_carrier_[Bombyx_mori]

Location

Bomo_Chr21(-):725346-726536      View in EpiBrowser

Full name

Phosphate carrier protein, mitochondrial      

Alternative Name

Phosphate transport protein
Solute carrier family 25 member 3

Location in the cell

Mitochondrial   Reliability : 1.309 PlasmaMembrane   Reliability : 1.776

CDS

ATGTCGAAGAAGCCCAAAGAAGAGTTCTCTTGTGAGATGTACAGCAACAAATACTTCATGCTGTGCGCTTACGGAGGCGCCTGTGCTTGCGGGATCACGCATACCTTCGTTACACCTCTGGACTTGGTCAAGTGCCGCCTGCAAGTTGACCCGGCCAAATACAAATCCATATTTAAAGGATTCGGGATATCTATCAAAGAAGGCGGCGCTGCTAACCTCGTAAAAGGCTGGGCACCTACGCTCATAGGCTATTCTATGCAAGGTTCGTCAAAATTTGCTGGCTACGAATACTTCAAGTACAAATTCTCCAAAATGGTTGATGAAGAATCGGCGTACTTATACAGAACTTACCTGTATTTAGCTGCTGCAGCATCGGCCGAATGCATAGCTGATATCTTCCTTTCTCCTTTCGAAGCCACTAAAGTCCGGATACAAACAACGCCGGGGTACACGTCAAAGATGCGGAAGGCCATGCCACATATGCTGGCCACAGAAGGCTTTGGAGTCTTTTACCGTGGCTTAGTGCCGTTATGGGGGCGACAAATTCCCTACACTATGATGAAATTCGCGTCTTTCGAGAAAACACTTGAGTACTTGTATGAGAATGTTGTGCCCAAGCCTCGTGACCAGTGCACCAAGATTGAGCAGCTCCTCGTTACGTTCACAGCTGGGTACATAGCTGGGGTGCTGTGCGCTATAGTGTCGCATCCAGCTGACACGATCGTTTCCAAGCTCAATAAGGACCCCGGGGCTTCGATCGGGGGTATCATAGCCGAAGTGGGGCCGATGGGCATCTGGCGAGGTCTAGTGGCTCGCATCATTATGATTGGCACCCTCACAGGACTGCAATGGTTTATTTATGACGGTTTCAAAGTGAAAATGGGTATGCCTCGGCCGCCTCCCGCAGAGATGCCAGAATCCCTTAGAAAGAAACTGGCGGCAAAGAAGTAA

Protein

MSKKPKEEFSCEMYSNKYFMLCAYGGACACGITHTFVTPLDLVKCRLQVDPAKYKSIFKGFGISIKEGGAANLVKGWAPTLIGYSMQGSSKFAGYEYFKYKFSKMVDEESAYLYRTYLYLAAAASAECIADIFLSPFEATKVRIQTTPGYTSKMRKAMPHMLATEGFGVFYRGLVPLWGRQIPYTMMKFASFEKTLEYLYENVVPKPRDQCTKIEQLLVTFTAGYIAGVLCAIVSHPADTIVSKLNKDPGASIGGIIAEVGPMGIWRGLVARIIMIGTLTGLQWFIYDGFKVKMGMPRPPPAEMPESLRKKLAAKK

Description

Transport of phosphate groups from the cytosol to mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP) (By similarity).

Subunit

Interacts with PPIF; the interaction is impaired by CsA.

Similarity

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Keywords

Acetylation   Complete proteome   Direct protein sequencing   Membrane   Methylation   Mitochondrion   Mitochondrion inner membrane   Phosphoprotein   Reference proteome   Repeat   Symport   Transit peptide   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Phosphate carrier protein, mitochondrial

Uniprot

H9JS70   Q1HPZ3   A0A0L7KWS6   A0A194RB49   A0A194PWB3   A0A212FBC8   + More
A0A2A4JMA3   A0A2W1BVT5   A0A1Y1BAL1   A0A2H1WXI2   A0A1Y1BFT4   S4NP70   A0A194Q714   A0A212EUL9   A0A2A4JB32   I4DMQ1   A0A1E1VYC1   A0A3S2NJD7   A0A1Y1LT60   A0A1Y1BB34   A0A194PNS2   A0A1W4XMU4   A0A3Q3GJI7   A0A1J1IQR2   A0A0H3YF60   A0A2P2HW29   Q1HPL2   B4KVN2   A0A0D2WPF4   A0A323TKV5   A0A3R7MZV2   A0A0L7QQT0   A0A1S3MJG2   A0A084VH95   A0A060VTC1   A0A3B1JXV6   A0A060XZK9   A0A3B1J3N7   H3B461   A0A2M4A0Z0   A0A0P4X221   A0A2R8RYH8   A0A182J9E5   A0A183TKT4   Q8VEM8   Q3THU8   Q3UB63   Q3U995   A0A0X3NIQ0   A0A1L8GUR0   A0A1Y9GKQ7   A0A1Y1BFQ2   A0A182VM57   C0H8G7   A0A1Y1BAN5   A0A182TT40   A0A1Y1BAN1   T1E7H4   A0A2R7VQM5   T1E7A2   A0A3P8XVY6   A0A182KXK4   Q7QAQ2   A0A182MRW1   A0A1Y9HFF3   A0A1Y9IVF8   A0A151X4T8   A0A1S3KRV5   B4LEW1   F1QAJ7   M3YIY8   A0A084VH94   A0A182Y7C8   E0VAU8   A0A1S3MK51   A0A1D1XFU7   A0A2D0SEK5   A0A182VEC5   A0A2D0SFX6   A0A1Y9GKR2   A0A182KXK1   F5HLB2   A0A3P7LCD2   A0A2D0SFA8   A0A151J292   A0A1S3FII6   B4GI12   A0A1Q3G4G4   Q6NWJ7   A0A3P8XU12   A0A0E9X6M7   Q28ZA7   F4WS22   Q7ZTJ1   A0A151JYY1   A0A3B4V668   C1BJE1   A0A3B0JCI6   A0A146WJW2   A0A026W7F0  

Pubmed

19121390    28224717    26227816    26354079    22118469    28756777    + More
23622113    22651552    28004739    26057828    17994087    24438588    24755649    25329095    9215903    23594743    16141072    15489334    21183079    23806337    23576753    10349636    11042159    11076861    11217851    12466851    16141073    27762356    20433749    25069045    20966253    12364791    14747013    17210077    25244985    20566863    25613341    15632085    21719571    24508170    30249741   

EMBL

BABH01033078    LC185244    BAX57167.1    DQ443259    ABF51348.1    JTDY01004977    + More
KOB67521.1    KQ460473    KPJ14495.1    KQ459591    KPI97049.1    AGBW02009347    OWR51045.1    NWSH01001051    PCG72916.1    KZ149941    PZC76910.1    LC185248    BAX57171.1    ODYU01011814    SOQ57773.1    LC185246    BAX57169.1    GAIX01011964    JAA80596.1    KQ459580    KPI99185.1    AGBW02012340    OWR45188.1    NWSH01002045    PCG69317.1    AK402569    BAM19191.1    GDQN01011329    JAT79725.1    RSAL01000072    RVE49066.1    GEZM01047428    JAV76842.1    LC185247    BAX57170.1    KQ459603    KPI92775.1    CVRI01000057    CRL02082.1    KT163645    AKN21595.1    IACF01000192    LAB65995.1    DQ443390    LC185243    ABF51479.1    BAX57166.1    CH933809    EDW19503.1    KE346365    KJE93245.1    MDVM02000098    PYZ99293.1    QCYY01002018    ROT73569.1    KQ414785    KOC60988.1    ATLV01013150    KE524842    KFB37339.1    FR904298    CDQ58193.1    FR906594    CDQ84906.1    AFYH01015166    GGFK01001122    MBW34443.1    GDRN01016809    JAI67835.1    CR855322    CU207255    UYSU01041945    VDM03468.1    AK077274    AK077723    AK088013    AK150641    AK150729    AK150870    AK151518    AK152006    AK152292    AK152341    AK167197    AK168580    BC018161    AK168129    BAE40098.1    AK151088    BAE30101.1    AK151887    BAE30772.1    GEEE01023912    JAP39313.1    CM004471    OCT87577.1    APCN01005530    LC185245    BAX57168.1    BT058623    BT060336    ACN10336.1    ACN12696.1    LC185260    BAX57183.1    LC185261    BAX57184.1    GAMD01003047    JAA98543.1    KK854006    PTY09131.1    GAMD01003222    JAA98368.1    AAAB01008888    EAA08862.4    AXCM01001020    KQ982543    KYQ55387.1    CH940647    EDW70218.1    AEYP01012179    AEYP01012180    KFB37338.1    DS235016    EEB10504.1    GDJX01026659    JAT41277.1    EGK97073.1    UYRU01050590    VDN11060.1    KQ980414    KYN16144.1    CH479183    EDW36132.1    GFDL01000354    JAV34691.1    BC067565    AAH67565.1    GBXM01010200    JAH98377.1    CM000071    EAL25707.1    GL888295    EGI63001.1    BC046849    CM004470    AAH46849.1    OCT88795.1    KQ981440    KYN41663.1    BT074720    ACO09144.1    OUUW01000001    SPP72930.1    GCES01056981    JAR29342.1    KK107364    QOIP01000007    EZA51918.1    RLU20419.1   

Proteomes

UP000005204    UP000037510    UP000053240    UP000053268    UP000007151    UP000218220    + More
UP000283053    UP000192223    UP000261660    UP000183832    UP000009192    UP000008743    UP000247427    UP000283509    UP000053825    UP000087266    UP000030765    UP000193380    UP000018467    UP000008672    UP000000437    UP000075880    UP000050788    UP000275846    UP000000589    UP000186698    UP000075840    UP000075903    UP000075902    UP000265140    UP000075882    UP000007062    UP000075883    UP000075900    UP000075920    UP000075809    UP000008792    UP000000715    UP000076408    UP000009046    UP000221080    UP000078492    UP000081671    UP000008744    UP000001819    UP000007755    UP000078541    UP000261420    UP000268350    UP000265000    UP000053097    UP000279307   

PRIDE

H9JS70    Q1HPZ3    Q1HPL2    Q8VEM8    Q3THU8    Q3UB63    + More
Q3U995    F1QAJ7    Q6NWJ7   

Pfam

PF00153   Mito_carr        + More
PF02893   GRAM

Interpro

IPR018108   Mitochondrial_sb/sol_carrier        + More
IPR023395   Mt_carrier_dom_sf       
IPR004182   GRAM       
IPR002067   Mit_carrier       

SUPFAM

SSF103506   SSF103506       

Gene 3D

1.50.40.10    

ProteinModelPortal

H9JS70   Q1HPZ3   A0A0L7KWS6   A0A194RB49   A0A194PWB3   A0A212FBC8   + More
A0A2A4JMA3   A0A2W1BVT5   A0A1Y1BAL1   A0A2H1WXI2   A0A1Y1BFT4   S4NP70   A0A194Q714   A0A212EUL9   A0A2A4JB32   I4DMQ1   A0A1E1VYC1   A0A3S2NJD7   A0A1Y1LT60   A0A1Y1BB34   A0A194PNS2   A0A1W4XMU4   A0A3Q3GJI7   A0A1J1IQR2   A0A0H3YF60   A0A2P2HW29   Q1HPL2   B4KVN2   A0A0D2WPF4   A0A323TKV5   A0A3R7MZV2   A0A0L7QQT0   A0A1S3MJG2   A0A084VH95   A0A060VTC1   A0A3B1JXV6   A0A060XZK9   A0A3B1J3N7   H3B461   A0A2M4A0Z0   A0A0P4X221   A0A2R8RYH8   A0A182J9E5   A0A183TKT4   Q8VEM8   Q3THU8   Q3UB63   Q3U995   A0A0X3NIQ0   A0A1L8GUR0   A0A1Y9GKQ7   A0A1Y1BFQ2   A0A182VM57   C0H8G7   A0A1Y1BAN5   A0A182TT40   A0A1Y1BAN1   T1E7H4   A0A2R7VQM5   T1E7A2   A0A3P8XVY6   A0A182KXK4   Q7QAQ2   A0A182MRW1   A0A1Y9HFF3   A0A1Y9IVF8   A0A151X4T8   A0A1S3KRV5   B4LEW1   F1QAJ7   M3YIY8   A0A084VH94   A0A182Y7C8   E0VAU8   A0A1S3MK51   A0A1D1XFU7   A0A2D0SEK5   A0A182VEC5   A0A2D0SFX6   A0A1Y9GKR2   A0A182KXK1   F5HLB2   A0A3P7LCD2   A0A2D0SFA8   A0A151J292   A0A1S3FII6   B4GI12   A0A1Q3G4G4   Q6NWJ7   A0A3P8XU12   A0A0E9X6M7   Q28ZA7   F4WS22   Q7ZTJ1   A0A151JYY1   A0A3B4V668   C1BJE1   A0A3B0JCI6   A0A146WJW2   A0A026W7F0  

PDB

2LCK     E-value=0.0120232,     Score=90

KEGG

732956    K15102 solute carrier family 25 (mitochondrial phosphate transporter), member 3 | (RefSeq) mitochond

GO

GO:0022857   GO:0016021   GO:0048190   GO:0035435   GO:0031305   GO:0005315   GO:0043209   GO:0005743   GO:0015293   GO:0005739   GO:0044877  

Subcellular location

Mitochondrion inner membrane  

Length:

316

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

88.12316

Exp number, first 60 AAs:

18.55735

Total prob of N-in:

0.87156

POSSIBLE N-term signal

sequence

inside

1  -  215

TMhelix

216  -  238

outside

239  -  263

TMhelix

264  -  286

inside

287  -  316

 

 

Pi

184.301381

Theta

195.13622

Tajima's D

-0.432806

CLR

0.016045

CSRT

0.254037298135093

Interpretation

Uncertain