Gene

KWMTBOMO12326

Annotation

PREDICTED:_uncharacterized_protein_LOC106710892_[Papilio_machaon]

Location

Bomo_Chr20(+):12202040-12204062      View in EpiBrowser

Full name

Retrovirus-related Pol polyprotein from transposon 17.6       + More
Retrovirus-related Pol polyprotein from transposon 297      

Location in the cell

Nuclear   Reliability : 2.612

CDS

ATGAGGGAAAGTATCTCCCCTTGGTCGTGCCCGGTACACATTGTTCCGAAAAAACCGGATGCATCAGGAAAAGTTAAATGGAGACTTGTTATTGACTATAGAAGACTTAATGACAGAATTATAGAAGACAAGTACCCCTTACCAAACATTAACGACATCCTTGACAGATTAGGGCGCGCACAATATTTCACGACCATAGATTTAGCAAGCGGCTACCATCAATTAGAAATGCACCCTAAAGACGTAGAGAAAACAGCGTTTACTACTGAAAGAGGCCACTATGAGTTCCTAAGAATGCCTTTCGGACTAAAAAATGCCCCGAGCACTTTCCAGCGTCTTATGGACCATATACTCCGAGGTATAGACAACGTATTTACGTACTTAGATGACGTCATAATAGCGGCGACGTCCCTACAAAACCACAATGAAAAACTGAAATTAGTATTTCAGCGATTCAAAATGCATAATCTGAAAGTTCAGTTAGACAAATCAGAATTTCTACAGAAGCACGTTAACTTTCTAGGACATGAATTGACTGACCAAGGACTAAATCCTAACAAGGACAAAATTAAAGCAGTATTAAATTTCCCTATACCACAAACGCAAAAAGACATAAAAGCTTTCTTAGGACTAGTCGGGTACTATAGGAAGTTTATTAAGGACTTTGCGAAGTTGACGAAACCTTTAACAGCATGTCTAAAAAAGAACGCAAAGGTTGAACATACAAACGAATTTTTAGACGCAGTTGATAAATGCAAACAAATTCTAACAAACGCCCCAATCCTGCAATACCCTGACTTCGACAAACCGTTTATTTTAACGACAGACGCATCTGACTTTGCTTTAGGAGCAGTACTTTCCCAAGGCAATGTGGGCTCAGATAAACCAGTAGCCTATGCCTCAAGGACATTATCAGATACTGAGATCCGTTACTCTACCATAGAGAAAGAACTGTTAGGGATAGTATGGGCAATTAAGTATTTTAGACCTTACTTATATGGCCGTAAATTTACAATTTATACGGACCATAGACCCCTTACATGGTTAATGAGTCTAAAGGACCCTAACTCTAAATTAACACGATGGAAACTAAAGTTAGCAGAGTATGATTACAAAGTTGTTTATAAAAAGGGCAAACAAAACACTAACGCAGATGCACTATCTCGAGCAAAAATTTTTCATAATAGTATAGACTCTCTAGCTGTTAATGTTGATGACAATAGTGATGAAAACATAATAAACAGAATATTCGAAAACGCCCGGAGACAGGCAGAGATAGAAACTAATGACCCGAATAACCAAGACAATGAACGTAACAATACTGACAATAACGACCAACCTTATAACAATAATGACGTAGAAATGACCAGTATCTATCCCTCTCAAATTGACGAAGAGACAGACACAAGGAGTGCAACAACAGTCGACCCCGATCAATTAGTTTCTACAAATCATACCCAACCTGATAATGAAAATAACGGTATCCCTATAATATCCGACGCTATTGATAGACAGTTGAAACAATTTTACGTTAGGTCCACACCAGGTTCTACATACAGAGTAGAGGACAGATCAACAAACTCTAGGACATTCAAAGGTTCATTAATCAATGCGACCTTTGCCTAA

Protein

MRESISPWSCPVHIVPKKPDASGKVKWRLVIDYRRLNDRIIEDKYPLPNINDILDRLGRAQYFTTIDLASGYHQLEMHPKDVEKTAFTTERGHYEFLRMPFGLKNAPSTFQRLMDHILRGIDNVFTYLDDVIIAATSLQNHNEKLKLVFQRFKMHNLKVQLDKSEFLQKHVNFLGHELTDQGLNPNKDKIKAVLNFPIPQTQKDIKAFLGLVGYYRKFIKDFAKLTKPLTACLKKNAKVEHTNEFLDAVDKCKQILTNAPILQYPDFDKPFILTTDASDFALGAVLSQGNVGSDKPVAYASRTLSDTEIRYSTIEKELLGIVWAIKYFRPYLYGRKFTIYTDHRPLTWLMSLKDPNSKLTRWKLKLAEYDYKVVYKKGKQNTNADALSRAKIFHNSIDSLAVNVDDNSDENIINRIFENARRQAEIETNDPNNQDNERNNTDNNDQPYNNNDVEMTSIYPSQIDEETDTRSATTVDPDQLVSTNHTQPDNENNGIPIISDAIDRQLKQFYVRSTPGSTYRVEDRSTNSRTFKGSLINATFA

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Miscellaneous

The open reading frame is located in a copia-like transposable element called 17.6.

Keywords

Aspartyl protease   Endonuclease   Hydrolase   Nuclease   Nucleotidyltransferase   Protease   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Retrovirus-related Pol polyprotein from transposon 17.6

Uniprot

V5GQE1   Q65353   D7EKG9   A0A3Q0JL77   A0A1Y1KML2   A0A1B6DI21   + More
A0A1B6E8Y4   A0A224XIQ6   V5FY26   A0A1W7R686   E0VZF9   V5I864   E0VZF7   A0A3Q0JCA5   A0A3Q0JG65   O46115   Q5BN17   A0A0A9XD39   A0A1Y1KJL2   A0A0A9XG63   A0A146KMA2   A0A224XA16   A0A1W7R6J9   U5ES61   A0A0K8S7R8   A0A0A9YJ44   A0A146L836   A0A1W7R6F0   D7GXP0   A0A0K8WF08   A0A023F0Y8   A0A023EZI9   A0A2S2NN14   A0A0K8WBI5   A0A023F0X4   A0A224XAI1   A0A2J7PEY0   A0A224XI86   A0A2J7RJQ6   A0A0A9XBE2   A0A0A9YU38   A0A2S2NLS2   A0A2J7QWM2   A0A2H8TVW1   A0A146LB26   A0A023F0J2   A0A0J7K6M0   A0A2J7RBZ9   A0A2S2NNZ3   X1WUD2   A0A0J7KFZ4   A0A2S2NFT1   V9H1K3   A0A2J7Q0T0   A0A2J7PPW9   P04323   A0A2J7PFW5   A0A0J7N7Q7   Q967T2   A0A2J7R948   P20825   X1X2K6   Q8T5U3   A0A0K8TRU1   A0A2S2QW04   A0A023EZI1   J9M441   A0A2J7PP03   X1WLD0   O96740   A0A023EYN5   A0A2J7QTC1   X1WM57   Q8IT56   A0A2S2PBQ7   A0A0K8TSF6   A0A0J7KIJ2   A0A2J7RRF2   A0A355BCA1   A0A0A1WP70   A0A023EXQ4   J9LRA5   A0A2J7PDA1   A0A2J7PRU8   A0A0K8W5P9   A0A1W7R6M6   T1E1D6   X1WLJ7   O76326   X1WLD3   A0A355BCF3   A0A2S2P749   X1XQI4  

Pubmed

1692964    18362917    19820115    28004739    20566863    9405380    + More
12537573    25401762    26823975    25474469    8035817    6209583    2417839    26369729    10331252    30148503    25830018    24330624    10571049   

EMBL

GALX01004629    JAB63837.1    M32662    AAA92249.1    DS497745    EFA13136.1    + More
GEZM01078735    JAV62639.1    GEDC01017847    GEDC01011974    JAS19451.1    JAS25324.1    GEDC01002915    JAS34383.1    GFTR01008505    JAW07921.1    GALX01005891    JAB62575.1    GEHC01000961    JAV46684.1    DS235852    EEB18765.1    GALX01005230    JAB63236.1    EEB18763.1    AJ000387    CAA04050.1    AY928610    AAX28844.1    GBHO01024992    JAG18612.1    GEZM01081533    JAV61609.1    GBHO01024993    JAG18611.1    GDHC01021754    JAP96874.1    GFTR01008672    JAW07754.1    GEHC01000905    JAV46740.1    GANO01002504    JAB57367.1    GBRD01016627    JAG49199.1    GBHO01012506    JAG31098.1    GDHC01015253    JAQ03376.1    GEHC01000906    JAV46739.1    GG694348    EFA13518.1    GDHF01002622    JAI49692.1    GBBI01004048    JAC14664.1    GBBI01004049    JAC14663.1    GGMR01005970    MBY18589.1    GDHF01004109    JAI48205.1    GBBI01004051    JAC14661.1    GFTR01008492    JAW07934.1    NEVH01026087    PNF14896.1    GFTR01008667    JAW07759.1    NEVH01002988    PNF41072.1    GBHO01026285    JAG17319.1    GBHO01007885    JAG35719.1    GGMR01005468    MBY18087.1    NEVH01009425    PNF32982.1    GFXV01006571    MBW18376.1    GDHC01013046    JAQ05583.1    GBBI01004233    JAC14479.1    LBMM01013045    KMQ85846.1    NEVH01005888    PNF38366.1    GGMR01006290    MBY18909.1    ABLF02041284    LBMM01008064    KMQ89174.1    GGMR01003444    MBY16063.1    Z24451    CAA80824.1    NEVH01019964    PNF22169.1    NEVH01022642    PNF18384.1    X01472    NEVH01025646    PNF15218.1    LBMM01008712    KMQ88680.1    AF364550    AAK52058.1    NEVH01006666    PNF37360.1    X03431    ABLF02024213    ABLF02042472    AF492764    AAM11674.1    GDAI01000740    JAI16863.1    GGMS01012487    MBY81690.1    GBBI01004050    JAC14662.1    NEVH01023280    PNF18074.1    ABLF02041728    AJ009736    CAA08807.1    GBBI01004444    JAC14268.1    NEVH01011195    PNF31840.1    ABLF02001345    ABLF02006651    ABLF02006655    ABLF02054079    ABLF02054906    ABLF02062695    AF541948    AAN34651.1    GGMR01014274    MBY26893.1    GDAI01000738    JAI16865.1    LBMM01007099    KMQ90041.1    NEVH01000607    PNF43410.1    DNYX01000282    HBK83635.1    GBXI01013483    JAD00809.1    GBBI01004677    JAC14035.1    ABLF02030471    ABLF02066562    NEVH01026392    PNF14303.1    NEVH01021952    PNF19057.1    GDHF01005932    JAI46382.1    GEHC01000875    JAV46770.1    GALA01001779    JAA93073.1    ABLF02011176    ABLF02041729    AF056940    AAC33318.1    ABLF02011604    ABLF02041632    DNYX01000239    HBK83403.1    GGMR01012631    MBY25250.1    ABLF02041376   

Proteomes

UP000007266    UP000079169    UP000009046    UP000235965    UP000036403    UP000007819    + More

PRIDE

O46115    Q5BN17    P04323    Q967T2    P20825    Q8T5U3    + More
O96740    Q8IT56   

Pfam

PF00078   RVT_1        + More
PF17921   Integrase_H2C2
PF17917   RT_RNaseH
PF00665   rve
PF17919   RT_RNaseH_2
PF02902   Peptidase_C48
PF00077   RVP
PF01661   Macro
PF12259   Baculo_F
PF00098   zf-CCHC

Interpro

IPR000477   RT_dom        + More
IPR012337   RNaseH-like_sf       
IPR041373   RT_RNaseH       
IPR036397   RNaseH_sf       
IPR041588   Integrase_H2C2       
IPR001584   Integrase_cat-core       
IPR001969   Aspartic_peptidase_AS       
IPR021109   Peptidase_aspartic_dom_sf       
IPR041577   RT_RNaseH_2       
IPR003653   Peptidase_C48_C       
IPR038765   Papain-like_cys_pep_sf       
IPR001995   Peptidase_A2_cat       
IPR002589   Macro_dom       
IPR018061   Retropepsins       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       
IPR022048   Envelope_fusion-like       

SUPFAM

SSF53098   SSF53098        + More
SSF50630   SSF50630       
SSF54001   SSF54001       
SSF57756   SSF57756       

Gene 3D

3.30.420.10     2.40.70.10    

ProteinModelPortal

V5GQE1   Q65353   D7EKG9   A0A3Q0JL77   A0A1Y1KML2   A0A1B6DI21   + More
A0A1B6E8Y4   A0A224XIQ6   V5FY26   A0A1W7R686   E0VZF9   V5I864   E0VZF7   A0A3Q0JCA5   A0A3Q0JG65   O46115   Q5BN17   A0A0A9XD39   A0A1Y1KJL2   A0A0A9XG63   A0A146KMA2   A0A224XA16   A0A1W7R6J9   U5ES61   A0A0K8S7R8   A0A0A9YJ44   A0A146L836   A0A1W7R6F0   D7GXP0   A0A0K8WF08   A0A023F0Y8   A0A023EZI9   A0A2S2NN14   A0A0K8WBI5   A0A023F0X4   A0A224XAI1   A0A2J7PEY0   A0A224XI86   A0A2J7RJQ6   A0A0A9XBE2   A0A0A9YU38   A0A2S2NLS2   A0A2J7QWM2   A0A2H8TVW1   A0A146LB26   A0A023F0J2   A0A0J7K6M0   A0A2J7RBZ9   A0A2S2NNZ3   X1WUD2   A0A0J7KFZ4   A0A2S2NFT1   V9H1K3   A0A2J7Q0T0   A0A2J7PPW9   P04323   A0A2J7PFW5   A0A0J7N7Q7   Q967T2   A0A2J7R948   P20825   X1X2K6   Q8T5U3   A0A0K8TRU1   A0A2S2QW04   A0A023EZI1   J9M441   A0A2J7PP03   X1WLD0   O96740   A0A023EYN5   A0A2J7QTC1   X1WM57   Q8IT56   A0A2S2PBQ7   A0A0K8TSF6   A0A0J7KIJ2   A0A2J7RRF2   A0A355BCA1   A0A0A1WP70   A0A023EXQ4   J9LRA5   A0A2J7PDA1   A0A2J7PRU8   A0A0K8W5P9   A0A1W7R6M6   T1E1D6   X1WLJ7   O76326   X1WLD3   A0A355BCF3   A0A2S2P749   X1XQI4  

PDB

4OL8     E-value=9.18711e-74,     Score=705

KEGG

105841962    no KO assigned | (RefSeq) protein PFC0760c-like

GO

GO:0015074   GO:0003676   GO:0004190   GO:0003964   GO:0004519   GO:0008234   GO:0005634   GO:0008270  

Length:

541

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00312

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00142

outside

1  -  541

 

 

Pi

1.085972

Theta

2.525181

Tajima's D

-1.41134

CLR

51.668666

CSRT

0.0632968351582421

Interpretation

Uncertain