Gene

KWMTBOMO12308

Pre Gene Modal

BGIBMGA009119

Annotation

PREDICTED:_actin-related_protein_8_[Papilio_xuthus]

Location

Bomo_Chr20(-):11916596-11918393      View in EpiBrowser

Full name

Actin-related protein 8      

Location in the cell

Cytoplasmic   Reliability : 2.47

CDS

ATGAGTATGGCATCGCATGATGCCGGCGTTCCTGAACAATTCCAGCAATTTCCGCCTAACAGAATCATTGTTATCCACCCTGGTTCGCTCTACGTACGTATCGGACGAGCCTCAGATCTCGTGCCAGTGAAACAGCTACACTGCATTGCAAGAAAACGTAGACACGGCGGCAAAATTTACCGCGACTCTTTCATACCACCGAGCGTTCCGAAAACCAAAGAATTGATTGAGGAATTAGAAGAATGTAGGCTTCAAATATCTCATACTCTTCAGTCATGTGTGCAGTCTAACGGCGCAAGAAGGTACGCAACTCCCCCGCAGCAAATCGCGGCCTTTAACCGTCGTTCGTTACCGGAGTACGTCTCTGACGGGGAACCGTGGCCTCAAGTCGAATGTGATGTTATTGTAGGTGATCTAGTCCTTGATGTGGACCCAGAATTACCATACAACATACATTTTCCATACCGTAGAGGAGATTTTAACCTTCATTCTGAAATAGGAGGATCTATTTCATCAGTTCTGAATGATCTGTATACAATATGGAGTTCCATAATTGAGTTTAAGTTAGGGATACCCCTGATAGAGCTTGTGAAATATAGATGTGTTCTTCTGATACCAGATCTGTACTGCAGGAGTCATTTAAAGTATCTAATGTCTTTACTGTTGAAGGACTTGGGCTTTGGCCATTGTTTCTTAGTCCAGGAAAGTGTTGGAGCTACATTCGGAGCAGGCATTGGTTCGGCCTGTGTGGTGGACATTGGTGATCAAAAAACAGCAATATCATGTGTTGAAGATGGTATCTCTCATAAACCAACTAGATTGAGAATGGACTATGGAGCTGGGGATGTCTGTCAGTCTCTATCATGGATGTTTCATAAGAGTGCATTTCCGTACAAGGACTGGACAGAGAATATACCACGAGATGTGGTTTTAATGCGAAATCTATATGAAAACTTTTGCCATATTAATTTGGATGTTTGTGGTCCACAAGAGAAGTCATTCTTGGTCGATCACCCAGGAGATGTAATCAATAAATATACACTCCAAGTTGGTGATGAATGCATAATATCACCATTATCAATGTTTTATACTGACTTACTGAAAATAACAGGTGCTAAAACTACTAAAATACCAAACAGACAGCCAAGTGATCCTGAAGATCCATTTGATGCAGAGTTTTTGAGGGAAACTGGTAGAAAGAAAGAAGCTATTGATATAAGCACCAATGAAAATCAATTTGAAACTCTCAATGAAATACAACAAGTGAATAACCAGGATGAAGACATAGTCGTAGATACATTAGAAGGGGGACCAGGAGACATTTCTTTATTAGCCCCAGGGCAAGTTATGGCCCTAGATGCTGCAATACTACAAAGCATAGATCGATGTCCCAGTGATGACCTGAAACGGAAGATGTACAGCAACGTTCTAATTGTCGGAGGTGGGGTTAAAGTTCATGGTATATCATTATGGCTACAAAATCGTATGGCACTGCAGATCCCCTATACTTATAAGACTGAGCAGCTGGAAATAGTGACATCACCTAAAGAAATTGATCCTGCCAGTACTGTGTGGAAGGGGGCTGCAGTCATGTCTTGCTTGGAGTCAGCTATAGAACTGTGGATTAATCAAAGTGAATGGAACAAATACGGTTTGCGAATTTTAAGAGAAAGGGCTCCGTTTATATGGTGA

Protein

MSMASHDAGVPEQFQQFPPNRIIVIHPGSLYVRIGRASDLVPVKQLHCIARKRRHGGKIYRDSFIPPSVPKTKELIEELEECRLQISHTLQSCVQSNGARRYATPPQQIAAFNRRSLPEYVSDGEPWPQVECDVIVGDLVLDVDPELPYNIHFPYRRGDFNLHSEIGGSISSVLNDLYTIWSSIIEFKLGIPLIELVKYRCVLLIPDLYCRSHLKYLMSLLLKDLGFGHCFLVQESVGATFGAGIGSACVVDIGDQKTAISCVEDGISHKPTRLRMDYGAGDVCQSLSWMFHKSAFPYKDWTENIPRDVVLMRNLYENFCHINLDVCGPQEKSFLVDHPGDVINKYTLQVGDECIISPLSMFYTDLLKITGAKTTKIPNRQPSDPEDPFDAEFLRETGRKKEAIDISTNENQFETLNEIQQVNNQDEDIVVDTLEGGPGDISLLAPGQVMALDAAILQSIDRCPSDDLKRKMYSNVLIVGGGVKVHGISLWLQNRMALQIPYTYKTEQLEIVTSPKEIDPASTVWKGAAVMSCLESAIELWINQSEWNKYGLRILRERAPFIW

Description

Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity).
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex (By similarity).

Subunit

Component of the chromatin remodeling Ino80 complex. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
Component of the chromatin remodeling Ino80 complex. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core (By similarity).

Similarity

Belongs to the actin family. ARP8 subfamily.

Keywords

ATP-binding   Complete proteome   DNA damage   DNA recombination   DNA repair   Nucleotide-binding   Nucleus   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Actin-related protein 8

Uniprot

H9JHX1   A0A2W1BWJ4   A0A2H1W671   A0A194QC69   A0A3S2M8L0   A0A0N1PH44   + More
A0A0L7L615   A0A1B0DK17   A0A154PBF3   A0A2J7RID9   A0A182PN65   A0A067R771   A0A1B6G4T7   A0A182YAA3   A0A182KGR6   A0A182WE96   A0A182I632   A0A310SHB3   A0A182MIY0   A0A182UEY8   A0A0L7RA57   A0A182WY12   A0A182RLW6   A0A182KUX9   A0A232F6I9   A0A2A3ECW6   E2B5H2   A0A087ZSI3   A0A182MXU6   A0A195DG46   A0A1B6E7U9   N6TSR3   Q7QE38   N6SSM7   A0A151X8U7   A0A182QBL8   K7J695   A0A182SRP2   A0A026WIR6   D7EII7   Q0IEG8   A0A158NRN8   F4X3I6   A0A195CJ49   A0A0J7KBB5   A0A182IV85   A0A1B0CFG2   A0A0N0BGH7   A0A1Y1LSG2   B0WBI6   A0A182US49   A0A195BLS5   A0A336MA12   E0VW70   A0A084W3Z0   A0A023F1C7   A0A195EX39   T1HMN4   A0A069DVR2   A0A336MI83   A0A0P4WLB0   A0A0P4VPK2   A0A3R7LTB6   A0A1B6CUC1   A0A146LP00   A0A146L1Q4   A0A1J1HYD6   A0A224XBS2   A0A2R7WPQ8   A0A1W4XC13   E2AMT3   A0A0N8BJF1   A0A1Y1LXL2   E9HJ50   A0A0N8AN49   A0A2M4ANL6   A0A2M4ANI6   A0A2M4ANR1   W8BZ87   A0A0L0BS61   T1JFQ7   A0A2M4CIZ5   A0A0P4XAE8   A0A2M4CIN1   A0A0V0GBH8   A0A1B6ESE7   A0A2H8TWT6   A0A1Y1LVY2   A0A2S2PUS2   A0A0A1X2R9   J9JPK4   A0A034W7G6   A0A0P5TKN4   A0A1A9X7S9   A0A087TH52   A0A1A9Z4Q3   A0A182FT69   A0A1I8PHJ4  

Pubmed

19121390    28756777    26354079    26227816    24845553    25244985    + More
20966253    28648823    20798317    23537049    12364791    14747013    17210077    20075255    24508170    30249741    18362917    19820115    17510324    21347285    21719571    28004739    20566863    24438588    25474469    26334808    27129103    26823975    21292972    24495485    26108605    25830018    25348373   

EMBL

BABH01035413    KZ149926    PZC77567.1    ODYU01006600    SOQ48580.1    KQ459193    + More
KPJ03019.1    RSAL01000012    RVE53473.1    KQ461072    KPJ09840.1    JTDY01002719    KOB70855.1    AJVK01066015    KQ434868    KZC09163.1    NEVH01003502    PNF40593.1    KK852898    KDR14149.1    GECZ01012446    JAS57323.1    APCN01003551    KQ759910    OAD61990.1    AXCM01005803    KQ414619    KOC67743.1    NNAY01000798    OXU26451.1    KZ288280    PBC29623.1    GL445827    EFN89058.1    KQ980886    KYN11816.1    GEDC01003311    JAS33987.1    APGK01002320    KB734730    ENN83519.1    AAAB01008848    EAA07029.4    APGK01058328    KB741288    KB632322    ENN70669.1    ERL92340.1    KQ982409    KYQ56793.1    AXCN02002116    KK107183    QOIP01000011    EZA55915.1    RLU16566.1    DS497681    EFA12035.1    CH477691    EAT37227.1    ADTU01024218    GL888613    EGI59014.1    KQ977649    KYN00766.1    LBMM01010292    KMQ87551.1    AJWK01010098    KQ435784    KOX74564.1    GEZM01049894    JAV75778.1    DS231879    EDS42425.1    KQ976439    KYM86679.1    UFQT01000611    SSX25729.1    DS235817    EEB17626.1    ATLV01020234    KE525296    KFB44934.1    GBBI01003385    JAC15327.1    KQ981931    KYN32793.1    ACPB03003866    GBGD01001097    JAC87792.1    SSX25728.1    GDRN01039545    JAI67190.1    GDKW01001664    JAI54931.1    QCYY01003365    ROT63840.1    GEDC01020280    JAS17018.1    GDHC01009001    GDHC01004358    JAQ09628.1    JAQ14271.1    GDHC01017472    JAQ01157.1    CVRI01000036    CRK92971.1    GFTR01006611    JAW09815.1    KK855239    PTY21608.1    GL440893    EFN65256.1    GDIQ01171851    JAK79874.1    GEZM01049895    JAV75777.1    GL732660    EFX68180.1    GDIQ01259467    JAJ92257.1    GGFK01009050    MBW42371.1    GGFK01009029    MBW42350.1    GGFK01009051    MBW42372.1    GAMC01004569    GAMC01004567    JAC01989.1    JRES01001442    KNC22890.1    JH432185    GGFL01001041    MBW65219.1    GDIP01245455    JAI77946.1    GGFL01001042    MBW65220.1    GECL01000835    JAP05289.1    GECZ01028918    JAS40851.1    GFXV01006446    MBW18251.1    GEZM01049896    JAV75776.1    GGMR01020455    MBY33074.1    GBXI01008905    JAD05387.1    ABLF02019315    GAKP01008725    JAC50227.1    GDIP01142445    JAL61269.1    KK115211    KFM64441.1   

Proteomes

UP000005204    UP000053268    UP000283053    UP000053240    UP000037510    UP000092462    + More
UP000076502    UP000235965    UP000075885    UP000027135    UP000076408    UP000075881    UP000075920    UP000075840    UP000075883    UP000075902    UP000053825    UP000076407    UP000075900    UP000075882    UP000215335    UP000242457    UP000008237    UP000005203    UP000075884    UP000078492    UP000019118    UP000007062    UP000030742    UP000075809    UP000075886    UP000002358    UP000075901    UP000053097    UP000279307    UP000007266    UP000008820    UP000005205    UP000007755    UP000078542    UP000036403    UP000075880    UP000092461    UP000053105    UP000002320    UP000075903    UP000078540    UP000009046    UP000030765    UP000078541    UP000015103    UP000283509    UP000183832    UP000192223    UP000000311    UP000000305    UP000037069    UP000007819    UP000092443    UP000054359    UP000092445    UP000069272    UP000095300   

PRIDE

H9JHX1   

Pfam

PF00022   Actin        + More
PF01127   Sdh_cyt
PF05160   DSS1_SEM1

Interpro

IPR004000   Actin        + More
IPR027668   Arp8/plant_Arp9       
IPR034804   SQR/QFR_C/D       
IPR014314   Succ_DH_cytb556       
IPR000701   SuccDH_FuR_B_TM-su       
IPR018495   Succ_DH_cyt_bsu_CS       
IPR007834   DSS1_SEM1       
IPR018181   Heat_shock_70_CS       

SUPFAM

SSF81343   SSF81343       

Gene 3D

1.20.1300.10    

ProteinModelPortal

H9JHX1   A0A2W1BWJ4   A0A2H1W671   A0A194QC69   A0A3S2M8L0   A0A0N1PH44   + More
A0A0L7L615   A0A1B0DK17   A0A154PBF3   A0A2J7RID9   A0A182PN65   A0A067R771   A0A1B6G4T7   A0A182YAA3   A0A182KGR6   A0A182WE96   A0A182I632   A0A310SHB3   A0A182MIY0   A0A182UEY8   A0A0L7RA57   A0A182WY12   A0A182RLW6   A0A182KUX9   A0A232F6I9   A0A2A3ECW6   E2B5H2   A0A087ZSI3   A0A182MXU6   A0A195DG46   A0A1B6E7U9   N6TSR3   Q7QE38   N6SSM7   A0A151X8U7   A0A182QBL8   K7J695   A0A182SRP2   A0A026WIR6   D7EII7   Q0IEG8   A0A158NRN8   F4X3I6   A0A195CJ49   A0A0J7KBB5   A0A182IV85   A0A1B0CFG2   A0A0N0BGH7   A0A1Y1LSG2   B0WBI6   A0A182US49   A0A195BLS5   A0A336MA12   E0VW70   A0A084W3Z0   A0A023F1C7   A0A195EX39   T1HMN4   A0A069DVR2   A0A336MI83   A0A0P4WLB0   A0A0P4VPK2   A0A3R7LTB6   A0A1B6CUC1   A0A146LP00   A0A146L1Q4   A0A1J1HYD6   A0A224XBS2   A0A2R7WPQ8   A0A1W4XC13   E2AMT3   A0A0N8BJF1   A0A1Y1LXL2   E9HJ50   A0A0N8AN49   A0A2M4ANL6   A0A2M4ANI6   A0A2M4ANR1   W8BZ87   A0A0L0BS61   T1JFQ7   A0A2M4CIZ5   A0A0P4XAE8   A0A2M4CIN1   A0A0V0GBH8   A0A1B6ESE7   A0A2H8TWT6   A0A1Y1LVY2   A0A2S2PUS2   A0A0A1X2R9   J9JPK4   A0A034W7G6   A0A0P5TKN4   A0A1A9X7S9   A0A087TH52   A0A1A9Z4Q3   A0A182FT69   A0A1I8PHJ4  

PDB

4FO0     E-value=9.55628e-111,     Score=1025

KEGG

101740322    K11673 actin-related protein 8 | (RefSeq) actin-related protein 8

GO

GO:0031011   GO:0006338   GO:0005524   GO:0006281   GO:0006310   GO:0005634   GO:0045281   GO:0006099   GO:0016021   GO:0009055   GO:0000104   GO:0006355   GO:0043044   GO:0006302   GO:0032508   GO:0006351   GO:0043248   GO:0008541   GO:0006406  

PANTHER

PTHR11937   PTHR11937:SF13  

Subcellular location

Nucleus  

Length:

563

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.2704

Exp number, first 60 AAs:

0.00094

Total prob of N-in:

0.00231

outside

1  -  563

 

 

Pi

1.655816

Theta

5.026295

Tajima's D

-1.885168

CLR

18.113904

CSRT

0.0173491325433728

Interpretation

Uncertain