Gene

KWMTBOMO12245  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014138

Annotation

PREDICTED:_carbonyl_reductase_[NADPH]_3-like_[Papilio_machaon]

Location

Bomo_Chr20(-):10358420-10359589      View in EpiBrowser

Full name

Transmembrane 9 superfamily member      

Location in the cell

Cytoplasmic   Reliability : 2.588

CDS

ATGTCTCAAAAAGTAGCTATTATTATTAACGGGACTAATATTTTGGGTCTTGCTATTGTTAAAGCTTTAAGTGAAAAATTAAATGGCACTGTTTATTTCACCGCCTCGGATGAAGAAGAAGGGTTAAAAGCTACAGAAAATTTTAACAACATTGGTTTGTATCCAAAATTCCTCCTCGCACAAATCACTGACAAGCCCGCTCTGAAAAAGATTGCAGATACAATTCAAATGAACCATGGCAGCTTTGATATATTAATAAATAATACGGAGGACTTAAAACAATGTGAAGATTTTCCAACTTACGAAGAAGCTAAAAATGTTATTGACTCGAAGTACAAAAGTTTGTTAATTGTAGAGCAGTATTTGTTTCCTCTACTAAAAGATAGCGGTAGAGTCATCAATGTCACAAATGCATATGGTCATCTTTCGAACATAAAGAATGACAAATGGATCAAAACCCTTACGGCTCCAGATTTAACGGTAGAACAAATTGATAATTTGTTTGTAGAGGAGTATTTACGAAGCTTAGAAAATGGAAAGTTCGATAAAAAATGGTTCAGTGATGACGGAAAAATTGCGGAATATAAAATCTCAATGGTTGCTCGGACTGCCCTAACGTTTGTGTGGCAGAATAAATATAAAAGTAGAAATATTTGCGTTAATGCTGTTTATCCTAGATTGTTGGCTTTAGATATGGAAAGCGCTGAAGAGTCAATCAAAGCTATCCTATATCTAATTTTCGAAGCCTCGCCAAAGTTAACTGGAACTTTTATGTGGCATAACAAGAAACTAATTGACTGGTACGATACAGAAAGTGATTATTCGTGTAAAGATGTTACCTTAGAGTAA

Protein

MSQKVAIIINGTNILGLAIVKALSEKLNGTVYFTASDEEEGLKATENFNNIGLYPKFLLAQITDKPALKKIADTIQMNHGSFDILINNTEDLKQCEDFPTYEEAKNVIDSKYKSLLIVEQYLFPLLKDSGRVINVTNAYGHLSNIKNDKWIKTLTAPDLTVEQIDNLFVEEYLRSLENGKFDKKWFSDDGKIAEYKISMVARTALTFVWQNKYKSRNICVNAVYPRLLALDMESAEESIKAILYLIFEASPKLTGTFMWHNKKLIDWYDTESDYSCKDVTLE

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.

Uniprot

H9JX73   A0A2A4IZP8   A0A2A4IS40   A0A2W1BHX9   A0A2H1WY85   A0A0N0PAU9   + More
A0A0L7L0Z3   S4PV51   A0A194QFC8   A0A3S2LQT4   A0A194Q0C3   H9J991   A0A2A4JNM1   A0A2W1BQF4   A0A2W1BQ78   A0A194R7T9   A9NX88   A0A2A4JMV1   D2SNQ5   A0A194PZI3   A0A0L7L987   A0A194Q4V7   A0A194PYN6   A0A194PYP0   A0A194RBM8   A0A2H1VKT8   A0A212FD24   A0A2H1WXI4   H9J0E3   A0A212FD16   A0A194R6L7   S4PFV4   A0A194PJW2   A0A194QM92   A0A212FD48   A0A194REE5   A0A194QI05   A0A0L7LKQ9   J3JTF1   A0A194PVS9   I4DL03   V5GN34   A0A067QQ25   A0A2H1VYG7   A0A2S2QWN2   A0A0N1I826   A0A0N1IER6   A0A0L7KMS8   H9JV01   A0A1B6KVH8   D6WUE0   A0A1B6EX40   A0A1B6MDD4   A0A2L2XX45   A0A2J7Q296   A0A293LMB4   A0A2H1VYG0   A0A1B6ITF8   A0A1B6M714   A0A1B6C7K7   A0A1W4X692   A0A1Y1KDA4   A0A1B6CF00   R4FNV0   A0A2H8TPU2   A0A1B6FR44   A0A0A9W0V9   A0A0P4VRW6   J3JU59   A0A2L2XX33   A0A026W029   A0A2L2XZY9   A0A023FKP1   A0A2A4IVK8   A0A1D1UI99   G3MQJ3   A0A023GK08   A0A023FD31   N6SVP2   A0A131XBH7   A0A146M3D6   A0A131XVV1   A0A023F803   L7M4D0   A0A0P4WEW6   A0A195BW15   X1WKT7   A0A131Z4Y0   A0A224YLL4   J9JTT3   J9JZ17   A0A023GHB1   J9K943   A0A023GHC5   A0A224YJ66   A0A2H1VPT5   A0A2S2P3G7   T1L279   A0A1E1XAN7   A0A1Y1NF00  

Pubmed

19121390    28756777    26354079    26227816    23622113    18854048    + More
20074338    22118469    22516182    22651552    24845553    18362917    19820115    26561354    28004739    25401762    27129103    24508170    30249741    27649274    22216098    23537049    28049606    26823975    25474469    25576852    26830274    28797301    28503490   

EMBL

BABH01035856    NWSH01004922    PCG64583.1    NWSH01008342    PCG62595.1    KZ150152    + More
PZC72817.1    ODYU01011980    SOQ58033.1    KQ461157    KPJ08086.1    JTDY01003824    KOB68949.1    GAIX01009148    JAA83412.1    KQ459053    KPJ04248.1    RSAL01000405    RVE41893.1    KQ459584    KPI98444.1    BABH01004306    NWSH01000963    PCG73376.1    KZ149934    PZC77228.1    PZC77229.1    KQ460644    KPJ13305.1    EF085953    ABK25249.1    PCG73377.1    EZ407185    ACX53746.1    KPI98448.1    JTDY01002114    KOB72078.1    KPI98445.1    KPI98447.1    KPI98446.1    KPJ13306.1    ODYU01003092    SOQ41411.1    AGBW02009113    OWR51646.1    ODYU01011824    SOQ57785.1    BABH01010518    OWR51645.1    KPJ13307.1    GAIX01003872    JAA88688.1    KQ459601    KPI93721.1    KQ461196    KPJ06479.1    AGBW02009105    OWR51675.1    KQ460325    KPJ15839.1    KQ459193    KPJ03086.1    JTDY01000815    KOB75776.1    BT126507    AEE61471.1    KQ459597    KPI95235.1    AK401971    BAM18593.1    GALX01002952    JAB65514.1    KK853628    KDR03826.1    ODYU01005228    SOQ45879.1    GGMS01012953    MBY82156.1    KQ460466    KPJ14621.1    KPJ14619.1    JTDY01008746    KOB64420.1    BABH01037460    GEBQ01024723    JAT15254.1    KQ971352    EFA07299.1    GECZ01027302    JAS42467.1    GEBQ01006036    JAT33941.1    IAAA01002236    IAAA01002237    LAA00596.1    NEVH01019373    PNF22703.1    GFWV01004268    MAA28998.1    SOQ45880.1    GECU01027825    GECU01017498    JAS79881.1    JAS90208.1    GEBQ01008269    JAT31708.1    GEDC01027847    GEDC01011823    JAS09451.1    JAS25475.1    GEZM01088470    JAV58180.1    GEDC01025309    JAS11989.1    ACPB03015037    GAHY01001144    JAA76366.1    GFXV01004412    MBW16217.1    GECZ01017087    GECZ01016387    JAS52682.1    JAS53382.1    GBHO01042553    GBRD01010365    JAG01051.1    JAG55459.1    GDKW01001428    JAI55167.1    BT126771    AEE61733.1    IAAA01002234    LAA00586.1    KK107519    QOIP01000009    EZA49372.1    RLU19123.1    IAAA01002233    LAA00580.1    GBBK01003249    JAC21233.1    NWSH01006830    PCG63222.1    BDGG01000001    GAU88105.1    JO844144    AEO35761.1    GBBM01002050    JAC33368.1    GBBK01005242    JAC19240.1    APGK01054937    KB741253    KB632340    ENN71824.1    ERL92968.1    GEFH01004098    JAP64483.1    GDHC01005333    JAQ13296.1    GEFM01004999    JAP70797.1    GBBI01001358    JAC17354.1    GACK01007031    JAA58003.1    GDRN01075845    JAI62981.1    KQ976398    KYM92777.1    ABLF02035864    GEDV01003386    JAP85171.1    GFPF01005493    MAA16639.1    ABLF02035856    GBBM01002052    JAC33366.1    GBBM01002051    JAC33367.1    GFPF01006552    MAA17698.1    ODYU01003722    SOQ42855.1    GGMR01011273    MBY23892.1    CAEY01000925    GFAC01003037    JAT96151.1    GEZM01008630    JAV94726.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000037510    UP000053268    UP000283053    + More
UP000007151    UP000027135    UP000007266    UP000235965    UP000192223    UP000015103    UP000053097    UP000279307    UP000186922    UP000019118    UP000030742    UP000078540    UP000007819    UP000015104   

PRIDE

H9JX73    H9J991    H9J0E3    H9JV01    G3MQJ3   

Pfam

PF00106   adh_short        + More
PF00149   Metallophos
PF02872   5_nucleotid_C
PF02990   EMP70

Interpro

IPR002347   SDR_fam        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR008334   5'-Nucleotdase_C       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR036907   5'-Nucleotdase_C_sf       
IPR041821   CG11883_N       
IPR006179   5_nucleotidase/apyrase       
IPR029052   Metallo-depent_PP-like       
IPR004240   EMP70       
IPR020846   MFS_dom       
IPR020904   Sc_DH/Rdtase_CS       

SUPFAM

SSF51735   SSF51735        + More
SSF55816   SSF55816       

Gene 3D

3.60.21.10     3.90.780.10    

CDD

cd07406  MPP_CG11883_N
cd06174  MFS

ProteinModelPortal

H9JX73   A0A2A4IZP8   A0A2A4IS40   A0A2W1BHX9   A0A2H1WY85   A0A0N0PAU9   + More
A0A0L7L0Z3   S4PV51   A0A194QFC8   A0A3S2LQT4   A0A194Q0C3   H9J991   A0A2A4JNM1   A0A2W1BQF4   A0A2W1BQ78   A0A194R7T9   A9NX88   A0A2A4JMV1   D2SNQ5   A0A194PZI3   A0A0L7L987   A0A194Q4V7   A0A194PYN6   A0A194PYP0   A0A194RBM8   A0A2H1VKT8   A0A212FD24   A0A2H1WXI4   H9J0E3   A0A212FD16   A0A194R6L7   S4PFV4   A0A194PJW2   A0A194QM92   A0A212FD48   A0A194REE5   A0A194QI05   A0A0L7LKQ9   J3JTF1   A0A194PVS9   I4DL03   V5GN34   A0A067QQ25   A0A2H1VYG7   A0A2S2QWN2   A0A0N1I826   A0A0N1IER6   A0A0L7KMS8   H9JV01   A0A1B6KVH8   D6WUE0   A0A1B6EX40   A0A1B6MDD4   A0A2L2XX45   A0A2J7Q296   A0A293LMB4   A0A2H1VYG0   A0A1B6ITF8   A0A1B6M714   A0A1B6C7K7   A0A1W4X692   A0A1Y1KDA4   A0A1B6CF00   R4FNV0   A0A2H8TPU2   A0A1B6FR44   A0A0A9W0V9   A0A0P4VRW6   J3JU59   A0A2L2XX33   A0A026W029   A0A2L2XZY9   A0A023FKP1   A0A2A4IVK8   A0A1D1UI99   G3MQJ3   A0A023GK08   A0A023FD31   N6SVP2   A0A131XBH7   A0A146M3D6   A0A131XVV1   A0A023F803   L7M4D0   A0A0P4WEW6   A0A195BW15   X1WKT7   A0A131Z4Y0   A0A224YLL4   J9JTT3   J9JZ17   A0A023GHB1   J9K943   A0A023GHC5   A0A224YJ66   A0A2H1VPT5   A0A2S2P3G7   T1L279   A0A1E1XAN7   A0A1Y1NF00  

PDB

1N5D     E-value=5.85255e-15,     Score=195

KEGG

101741955    K00079 carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197] | (RefSeq) carbonyl reductase [NADPH]

PATHWAY

00590    Arachidonic acid metabolism - Bombyx mori (domestic silkworm)
00790    Folate biosynthesis - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0016491  

PANTHER

PTHR11575   PTHR10766  

Length:

282

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.50202000000001

Exp number, first 60 AAs:

2.46391

Total prob of N-in:

0.16026

outside

1  -  282

 

 

Pi

332.115361

Theta

227.599389

Tajima's D

1.446131

CLR

0.087422

CSRT

0.771711414429278

Interpretation

Uncertain