Gene

KWMTBOMO12205  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014181

Annotation

PREDICTED:_trifunctional_enzyme_subunit_beta?_mitochondrial_[Bombyx_mori]

Location

Bomo_Chr20(+):9347730-9360049      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 3.189

CDS

ATGGCTTCACAAGTCGCTAAATCATTGATAAAAGCAAACCACGTACGATCTACTGTTAAGTTCGATACTGCCAGACGAGCGCTGAGTGTAGCGCCAGTACTGCAGCAGAAGAAATCTCTCCCAGACCGTACAGGCAAGAATGTGGTGCTTGTCGATGGAGTCCGCACTCCATTCCTTGTTTCATTCACCGATTATGCCAGGATGATGCCCCATGAACTAGCAAGACATGCACTTCTTGGTCTCCTACAAAAGACTGGTATATCGAAGGATGTCATTGACTACATTGTATATGGCACCGTGATCCAAGAGGTGAAAACTTCAAATATAGGGCGCGAGGCAGCCCTGGCGGCTGGGTTCAGCGACAGGACTCCAGCGCACACCGTCACCATGGCTTGCATCTCTTCTAACCAGGCAATCACCACTGGTATCGGTATGATAGCGGCCGGCGCGTATGACGTCATCGTGGCTGGCGGAGTGGAGTTCATGTCGGACGTGCCCATCCGCCACTCGCGCAAGATGCGCTCGCTGCTGCTGCGGATCAACCGCGCCAAGACCCCGGCGCAGAGGCTATCGCTCATTGCCTCCATACGACCGGACTTCTTCGCTCCCGAGCTGCCTGCCGTGGCGGAGTTCTCGTCGGGCGAGACCATGGGCCACAGCGCGGACCGGCTGGCGGCCGCCTTCGGAGCCTCGCGACTGGAGCAGGACCAGTACGCGCTGCGCTCGCACACACTCGCCCACGAGGCCCAGCAGAAGGGATACTTCACGGACCTCATACCGGTCAAAGTGGACGGCAAGGACGGGCTGGTGGACAAGGACAACGGCATCCGCGTGTCCGCCCCCGAGCAGCTCGCCAAGCTGAAGCCGGCCTTCATCAAGCCGCACGGCACCGTCACCGCCGCCAACGCATCCTTCCTGACGGACGGCGCCTCCGCCTGCCTCGTGATGTCCGAGGCGAAGGCCAAGGAGCTCGGCCTCAAACCGAAGGCCTACCTGCGGGACTTCACCTACGTCGCTCAGGACCCCGTGGACCAGCTGCTGCTGGGGCCCGCCTACGGCATTCCCAAGATCTTGGACAAAGTCGGCCTCAAGGTCAACGATATCGACACGTGGGAGATCCATGAGGCCTTTGCGGGACAAATCCTGGCGAACTTGAAGGCTCTCGACTCGGACTGGTTCGGGCAGAAGTATCTGGGACGTCAAGGAAAGGTTGGCAGTCCGGACCTCGAGAAGTGGAACAAGTGGGGCGGCTCGCTCTCTATCGGACATCCATTCGCCGCCACCGGCGTTCGTCTGGCGATGCACACGGCTCACCGGCTGGTGCGGGAGGACGGGCAGTTCGGCGTCATCTCGGCCTGCGCGGCGGGAGGACAGGGAGTCGCCATGCTGCTGGAGAGACATCCTGATGCCACCACCCAATAA

Protein

MASQVAKSLIKANHVRSTVKFDTARRALSVAPVLQQKKSLPDRTGKNVVLVDGVRTPFLVSFTDYARMMPHELARHALLGLLQKTGISKDVIDYIVYGTVIQEVKTSNIGREAALAAGFSDRTPAHTVTMACISSNQAITTGIGMIAAGAYDVIVAGGVEFMSDVPIRHSRKMRSLLLRINRAKTPAQRLSLIASIRPDFFAPELPAVAEFSSGETMGHSADRLAAAFGASRLEQDQYALRSHTLAHEAQQKGYFTDLIPVKVDGKDGLVDKDNGIRVSAPEQLAKLKPAFIKPHGTVTAANASFLTDGASACLVMSEAKAKELGLKPKAYLRDFTYVAQDPVDQLLLGPAYGIPKILDKVGLKVNDIDTWEIHEAFAGQILANLKALDSDWFGQKYLGRQGKVGSPDLEKWNKWGGSLSIGHPFAATGVRLAMHTAHRLVREDGQFGVISACAAGGQGVAMLLERHPDATTQ

Similarity

Belongs to the thiolase-like superfamily. Thiolase family.
Belongs to the peptidase C1 family.

Uniprot

H9JXB6   A0A291P1A4   A0A291P143   A0A068FL96   A0A212FF05   A0A3S2NWP4   + More
D2XML2   S4NU14   A0A2M4A8C4   A0A182JSJ7   A0A182P7H8   A0A2M4BLX6   A0A1S3D5P3   A0A2M3Z1F6   A0A2M4CST8   A0A2M4CSI5   A0A182N3W1   T1DTD7   W5JKK8   A0A182QQ86   A0A182S542   A0A1Q3FHF7   A0A2M4CSD2   A0A182W1X3   Q17IM1   A0A182H0A5   A0A1L8DZE9   A0A182XGS3   A0A023EV11   A0A182VJV1   A0A182HHE0   A0A182FV00   A0A182UJJ1   A0A182LT25   A0A2H1VW16   U5ESQ9   A0A1S4H7M5   B0XFX4   A0A0K8TP31   W8AY77   A0A0P4VKN4   R4FKN5   A0A023F8U1   A0A182J8Z8   A0A336MRZ1   A0A224XPC0   A0A336MAH5   A0A069DUD0   A0A0V0G6N1   A0A0T6BEX1   V5GJ49   A0A1B6CAE5   A0A023ES23   D6WQQ7   A0A1Y1L6R7   A0A1B6EPZ4   B3MCL1   A0A2M3ZGA2   A0A0A1WPJ1   J9K674   A0A1W4V052   B4PA85   B4I8U9   B4QB11   B3NPU1   A0A120MH73   A0A1J1J0K9   A0A2H8TT56   A0A2S2R5H9   B4MRP8   A0A034WF11   Q9W1H8   A0A0K8UCN1   Q292R6   B4GCX3   A0A3B0JIT8   A0A034WAY5   A0A170Y1J7   N6U3E2   O77466   A0A1W4X610   A0A0L0CNA6   B4KMD6   A0A0A9YS83   A0A0M5IY19   A0A146M791   B4LNX7   A0A067RKB2   A0A1I8MDM6   A0A0A1WD76   A0A1I8PJ97   A0A1L8ED69   A0A1A9VU11   A0A2J7QAV1   A0A182SHN5   A0A1B0CR47   A0A1B0A1H2   A0A1B0FL92   A0A1A9XB59   A0A182YL99  

Pubmed

19121390    28986331    26385554    22118469    20074338    23622113    + More
20920257    23761445    17510324    26483478    24945155    12364791    26369729    24495485    27129103    25474469    26334808    18362917    19820115    28004739    17994087    25830018    17550304    22936249    25348373    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    23537049    10191082    26108605    25401762    26823975    24845553    25315136    25244985   

EMBL

BABH01035733    BABH01035734    MF706183    ATJ44610.1    MF687653    ATJ44579.1    + More
KJ622108    KJ579211    AID66698.1    AIN34687.1    AGBW02008885    OWR52300.1    RSAL01000042    RVE50797.1    GU205158    ADB57045.1    GAIX01011996    JAA80564.1    GGFK01003694    MBW37015.1    GGFJ01004945    MBW54086.1    GGFM01001570    MBW22321.1    GGFL01004063    MBW68241.1    GGFL01004061    MBW68239.1    GAMD01001019    JAB00572.1    ADMH02000915    ETN64676.1    AXCN02001095    GFDL01008058    JAV26987.1    GGFL01004062    MBW68240.1    CH477238    EAT46539.1    JXUM01022530    KQ560634    KXJ81503.1    GFDF01002429    JAV11655.1    GAPW01001279    JAC12319.1    APCN01002407    AXCM01000489    ODYU01004767    SOQ44998.1    GANO01002246    JAB57625.1    AAAB01008986    DS232970    EDS27093.1    GDAI01001948    JAI15655.1    GAMC01020756    GAMC01020754    GAMC01020751    GAMC01020749    JAB85806.1    GDKW01001685    JAI54910.1    ACPB03011673    GAHY01001768    JAA75742.1    GBBI01000861    JAC17851.1    UFQS01001990    UFQT01001990    SSX12889.1    SSX32331.1    GFTR01006555    JAW09871.1    UFQT01000630    SSX25899.1    GBGD01001329    JAC87560.1    GECL01003191    JAP02933.1    LJIG01001049    KRT85891.1    GALX01004372    JAB64094.1    GEDC01026904    JAS10394.1    GAPW01001570    JAC12028.1    KQ971354    EFA06041.1    GEZM01063157    GEZM01063156    JAV69264.1    GECZ01029771    JAS39998.1    CH902619    EDV36245.1    GGFM01006833    MBW27584.1    GBXI01013691    JAD00601.1    ABLF02034738    CM000158    EDW92411.1    CH480824    EDW57024.1    CM000362    CM002911    EDX08448.1    KMY96142.1    CH954179    EDV56882.1    KT768119    AMH84313.1    CVRI01000064    CRL05332.1    GFXV01004967    MBW16772.1    GGMS01015409    MBY84612.1    CH963850    EDW74787.1    GAKP01006257    JAC52695.1    AE013599    AY069124    AAF47083.1    AAL39269.1    GDHF01027920    JAI24394.1    CM000071    EAL24795.1    CH479181    EDW31511.1    OUUW01000001    SPP73156.1    GAKP01006256    JAC52696.1    GEMB01003799    JAR99454.1    APGK01041389    APGK01041390    KB740993    KB632256    ENN76085.1    ERL90698.1    AB010261    AB010262    BAA32690.1    JRES01000153    KNC33771.1    CH933808    EDW09824.1    GBHO01007707    GBRD01012983    GBRD01011121    GBRD01011119    JAG35897.1    JAG52843.1    CP012524    ALC42611.1    GDHC01002988    JAQ15641.1    CH940648    EDW61146.2    KK852423    KDR24252.1    GBXI01017348    JAC96943.1    GFDG01002276    JAV16523.1    NEVH01016325    PNF25699.1    AJWK01024391    CCAG010020375   

Proteomes

UP000005204    UP000007151    UP000283053    UP000075881    UP000075885    UP000079169    + More
UP000075884    UP000000673    UP000075886    UP000075900    UP000075920    UP000008820    UP000069940    UP000249989    UP000076407    UP000075903    UP000075840    UP000069272    UP000075902    UP000075883    UP000002320    UP000015103    UP000075880    UP000007266    UP000007801    UP000007819    UP000192221    UP000002282    UP000001292    UP000000304    UP000008711    UP000183832    UP000007798    UP000000803    UP000001819    UP000008744    UP000268350    UP000019118    UP000030742    UP000192223    UP000037069    UP000009192    UP000092553    UP000008792    UP000027135    UP000095301    UP000095300    UP000078200    UP000235965    UP000075901    UP000092461    UP000092445    UP000092444    UP000092443    UP000076408   

PRIDE

H9JXB6    Q9W1H8    O77466   

Pfam

PF00108   Thiolase_N        + More
PF02803   Thiolase_C
PF01275   Myelin_PLP
PF00112   Peptidase_C1
PF08246   Inhibitor_I29
PF15061   DUF4538
PF00025   Arf

Interpro

IPR002155   Thiolase        + More
IPR020613   Thiolase_CS       
IPR020610   Thiolase_AS       
IPR020616   Thiolase_N       
IPR020617   Thiolase_C       
IPR016039   Thiolase-like       
IPR020615   Thiolase_acyl_enz_int_AS       
IPR025661   Pept_asp_AS       
IPR000668   Peptidase_C1A_C       
IPR000169   Pept_cys_AS       
IPR001614   Myelin_PLP       
IPR013201   Prot_inhib_I29       
IPR025660   Pept_his_AS       
IPR038765   Papain-like_cys_pep_sf       
IPR039417   Peptidase_C1A_papain-like       
IPR027917   SMIM20       
IPR006689   Small_GTPase_ARF/SAR       
IPR027417   P-loop_NTPase       
IPR005225   Small_GTP-bd_dom       

SUPFAM

SSF53901   SSF53901        + More
SSF54001   SSF54001       
SSF52540   SSF52540       

Gene 3D

3.40.47.10    

CDD

cd00751  thiolase
cd02248  Peptidase_C1A

ProteinModelPortal

H9JXB6   A0A291P1A4   A0A291P143   A0A068FL96   A0A212FF05   A0A3S2NWP4   + More
D2XML2   S4NU14   A0A2M4A8C4   A0A182JSJ7   A0A182P7H8   A0A2M4BLX6   A0A1S3D5P3   A0A2M3Z1F6   A0A2M4CST8   A0A2M4CSI5   A0A182N3W1   T1DTD7   W5JKK8   A0A182QQ86   A0A182S542   A0A1Q3FHF7   A0A2M4CSD2   A0A182W1X3   Q17IM1   A0A182H0A5   A0A1L8DZE9   A0A182XGS3   A0A023EV11   A0A182VJV1   A0A182HHE0   A0A182FV00   A0A182UJJ1   A0A182LT25   A0A2H1VW16   U5ESQ9   A0A1S4H7M5   B0XFX4   A0A0K8TP31   W8AY77   A0A0P4VKN4   R4FKN5   A0A023F8U1   A0A182J8Z8   A0A336MRZ1   A0A224XPC0   A0A336MAH5   A0A069DUD0   A0A0V0G6N1   A0A0T6BEX1   V5GJ49   A0A1B6CAE5   A0A023ES23   D6WQQ7   A0A1Y1L6R7   A0A1B6EPZ4   B3MCL1   A0A2M3ZGA2   A0A0A1WPJ1   J9K674   A0A1W4V052   B4PA85   B4I8U9   B4QB11   B3NPU1   A0A120MH73   A0A1J1J0K9   A0A2H8TT56   A0A2S2R5H9   B4MRP8   A0A034WF11   Q9W1H8   A0A0K8UCN1   Q292R6   B4GCX3   A0A3B0JIT8   A0A034WAY5   A0A170Y1J7   N6U3E2   O77466   A0A1W4X610   A0A0L0CNA6   B4KMD6   A0A0A9YS83   A0A0M5IY19   A0A146M791   B4LNX7   A0A067RKB2   A0A1I8MDM6   A0A0A1WD76   A0A1I8PJ97   A0A1L8ED69   A0A1A9VU11   A0A2J7QAV1   A0A182SHN5   A0A1B0CR47   A0A1B0A1H2   A0A1B0FL92   A0A1A9XB59   A0A182YL99  

PDB

5ZRV     E-value=3.96181e-168,     Score=1519

KEGG

101738740    K07509 acetyl-CoA acyltransferase [EC:2.3.1.16] | (RefSeq) trifunctional enzyme subunit beta, mitoch

PATHWAY

00062    Fatty acid elongation - Bombyx mori (domestic silkworm)
00071    Fatty acid degradation - Bombyx mori (domestic silkworm)
00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0016747   GO:0016746   GO:0016021   GO:0008234   GO:0033617   GO:0005739   GO:0005525   GO:0006635   GO:0003988   GO:0004300   GO:0016508   GO:0016509   GO:0008340   GO:0016507   GO:0008152   GO:0003824   GO:0003676   GO:0016788   GO:0007165   GO:0008033   GO:0016787  

Length:

473

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.71951

Exp number, first 60 AAs:

0.00655

Total prob of N-in:

0.07158

outside

1  -  473

 

 

Pi

246.777722

Theta

173.910643

Tajima's D

1.929115

CLR

0.100579

CSRT

0.868756562171891

Interpretation

Uncertain