Silkworm Genome Informatics Database

Gene

KWMTBOMO12203

Pre Gene Modal

BGIBMGA014161

Annotation

vitellogenin_receptor_[Antheraea_pernyi]

Location

Bomo_Chr20(-):9315900-9331379 View in EpiBrowser

Full name

Vitellogenin receptor

Location in the cell

Extracellular Reliability : 1.807 Nuclear Reliability : 1.935

CDS

ATGGCCCGCCACATTTACTTCGGCGATGCTGAAAGGGGCCTGATCTTCGTATGCTACGATAGCGGCTTCAAATGTTTTACTTTGAAAGCTGACACCAAACATCCCAAGTTCATCACTCTGGACCCGGTGCACGGGAAGATGTACTGGGCCGATTGGCACAGCCGGCCGGTGATAATGAGGGCCAAGATGGACGGGTCGAGCTCTGAGGTGCTGGTAGAGTCGATGACGTCATTCGCCAGTGGCCTGGCGCTGGACGTGCCCAACGACAGACTCTACTTTGTTGATAAGACCATCAAAGTTGTTCTGCTAAGCACTAAGGTCGTTTACTCATTATTCAAAGAGGCCCACCACCATCCTTACGCGATATCGGTGTTCGAGAACACGGTGTACTGGAGCGATTGGATATCAGACTCCATCCAGACTACAGATAAGATTCACAGCTCTTCGCAGAGACAGGTGCTCCTCAAGATGGACACTTCGGTATTTGGTCTCCATATGTACCACCCAGCGTTGATGAAGAAGATTCCTCATCCGTGCGACGAGCACCCGTGCTCCCATTTCTGTCTGGTCACATCAATCGACACCTACTCGTGTGCTTGTCCAGACGAAATGGAAAACAAGAACGGCAGATGCATCCCCAAAGATGACTATCGCCCTCTGCATCTGATAGTCGGCAGCGGTAGACTGTTCACCAAGTTCCGGTTGGACGCCATGGGCAATCCGCACAGTCACGTCACCAACTTCTCCTTGGGACGCGTGCAAGCTATGACCTATGACTCTGTTCGAGATAGGCTGTATGTGTACGACGGTCGAGAGCACTCGATCAGCTATACGAACATGAGCGATTTCACTCACGGCAAAGTGTTCGCCCTGATCAAGTTCGGACCCGAGAACGTTGTCGATATGGACTACGATTACGTCTCGGACTCTCTGTACATGCTGGACTCTGGCAGCGGCTACATTGAGGTGTTGTCCTTGCGCACGCTACATCGCGCCGTCGTCTACCGCTTCACCGACCGGGAGACTCCCGTCAGCTTCTGCGTGCTGCCGCATTACGGGAAAATGTTGGTAGCGGTGATGCAGACGGATAACGACAACCGGATTTATGTGGACAGCATCGGCTTGGATGGAGACGGGAGGCGGCACATCGTCACCGTCAACATCAGAGGTCCCCGGATAATCCTGAGGTTCTTGCACGGCATGGACAATGTGTACCTGGCGGACGAGGGAAACGGCATCATAGATTACCTGCACCCTGAAGGTACCGGTAGGGAGAACTTCCGGGAGCTATCGACTTCAATATCCAGTATGGCTGTCACCGAAAACTATATATTCTGGACAGATAGAAGAACCCCGAAGCTATACTGGGCTAATATACACGAAACCTCTCATAAAATCAGAAGGATCGAACTTAGGGCATTCTCAAACTCCTCTCAGCTCCTGCTGCAGACCACGTACCCCCCACCGTCTCCTCACGACCCGCTCACCCAGCACCCGTGCCACAGAGACAACCCGTGCTCCCAGGTCTGCGTCCCGACCCATTCCCCCACGAACCCCTACAGCTATAAATGCCTCTGCTCTCCGGGCCTCGTGTTCAGTAACGGGAGATGCACGGAGGTGGCCAGATGCAGCGAAAGCGAAATTTACTGTCACAAAAGCAATATATGTGTGGAGAAACACAAGAGGTGCAATGGAGTCGTGGACTGTTCGAGGGGAGAAGACGAGGAAGGATGTACACATGTTACAAAGAAGTCCGAAAGCCAGTGCAACCCCAATGAGATACTCTGCTACGAGCTCTGCGTGGCGAAGGACTCTCCTTCCCCTTGTTCGCCTGAAAAGCATTCAGATATTACAAAGAAGCCCAAAAGTCAGTGCGACCCCAATGAGATACTCTGCTACGAGCTCTGCGTGGCTAAGGACTCCCCTTCCCCTTGTTCGCCTAAAAATCATTCAGATATTACAAAGAAGCCCGAAAACCAGTGCGACCCCAATGAGATACTCTGCTACGGGCTCTGCGTGGCTAAGGACTCTCCTTCCCCTTGTTCGTCTGAAAAGCATTCAGATATTACAAAGAAGCCCGAAAACCAGTGCGACCCCAATGAGATACTCTGTTACGGGCTCTGCGTGGCTAAGGACTCTCCTTCCCCTTGTTCGTCTGAAAAGCATTCAGATATTACAAAGAAGCCCGAAAACCAGTGCGACCCCAATGAGATACTCTGTTACGGGCTCTGCGTGGCTAAGGACTCTCCTTCCCCTTGTTCGTCTGAAAAGCATTCAGATATTACAAAGAAGCCCGAAAGCCAGTGCAACCCCAATGAGATACTCTGCTACGGACTTTGCGTGGCGAAGGACTCTCCTTCCCCTTGTTCGCCTGAAAAGCATTCAGATATTACAAAGAAGCCCGAAAGCCAGTGCGACCCCAATGAGATACTCTGCTACGGGCTCTGCGTGGCTAAGGACTCTCCTTCCCCTTGTTCGCCTGAAAAGCATTCAGATATTACAAAGAAGCCCGAAAGCCAATGCAACCCCAATGAGATACTCTGCTACGGACTTTGTGTGGCGAAGGACTCTCCTTCCCCTTGTTCGCCTGAAAAGAATTCAGATATTACAAAGAAGCCCGAAAGCCAGTGCGACCCCAATGAGATACTCTGCTACGGGCTCTGCGTGGCTAAGGACTCTCCTTCCCTTTGTTCGCCTGAAAAGCATTCAGATATTACAAAGAAGCCCGAAAGCCAATGCAACCCCAATGAGATACTCTGCTACGGACTTTGTGTGGCGAAGGACTCTCCTTCCCCTTGTTCGCCTGAAAAGAATTCAGATATTACAAAGAAGCCCGAAAGCCAGTGCGACCCCAATGAGATACTCTGCTACGGGCTCTGCGTGGCGAAGGATTCTCCTTCCCCTTGTTCACCTGAAAAACATTCAGATATTACAAAGCAGCCCGAAAGTCAGTGCGAACCCAATGAGATACTCTGCTACGGGCTCTGCGTGGCTAAGGACTCTCCTTCCCCTTGTTCGCCTGCGACACATTCAGTTGTTGCAGACCTGACGACCCCTCCCCCGCTGAAGTGCGACTGGATCCAGTTCTCGTGCAAGGAGAGCCCGGTCTGCATCTCGCGGTCGCTGCTCTGTGACGGAGCCAAGGACTGTCCGGACGGCAGCGACGAGGGCCCCGACAACTGTGACACCCTGGCCTGCTTTGACACGGAGTTCATGTGCGCGTCCGGTTCGTGCATCTTGAAAACGTGGAAGTGCGACGGAGACCAGGACTGCAACGACGCTTCCGATGAAATCGACTGTGGTCAGTGA

Protein

MARHIYFGDAERGLIFVCYDSGFKCFTLKADTKHPKFITLDPVHGKMYWADWHSRPVIMRAKMDGSSSEVLVESMTSFASGLALDVPNDRLYFVDKTIKVVLLSTKVVYSLFKEAHHHPYAISVFENTVYWSDWISDSIQTTDKIHSSSQRQVLLKMDTSVFGLHMYHPALMKKIPHPCDEHPCSHFCLVTSIDTYSCACPDEMENKNGRCIPKDDYRPLHLIVGSGRLFTKFRLDAMGNPHSHVTNFSLGRVQAMTYDSVRDRLYVYDGREHSISYTNMSDFTHGKVFALIKFGPENVVDMDYDYVSDSLYMLDSGSGYIEVLSLRTLHRAVVYRFTDRETPVSFCVLPHYGKMLVAVMQTDNDNRIYVDSIGLDGDGRRHIVTVNIRGPRIILRFLHGMDNVYLADEGNGIIDYLHPEGTGRENFRELSTSISSMAVTENYIFWTDRRTPKLYWANIHETSHKIRRIELRAFSNSSQLLLQTTYPPPSPHDPLTQHPCHRDNPCSQVCVPTHSPTNPYSYKCLCSPGLVFSNGRCTEVARCSESEIYCHKSNICVEKHKRCNGVVDCSRGEDEEGCTHVTKKSESQCNPNEILCYELCVAKDSPSPCSPEKHSDITKKPKSQCDPNEILCYELCVAKDSPSPCSPKNHSDITKKPENQCDPNEILCYGLCVAKDSPSPCSSEKHSDITKKPENQCDPNEILCYGLCVAKDSPSPCSSEKHSDITKKPENQCDPNEILCYGLCVAKDSPSPCSSEKHSDITKKPESQCNPNEILCYGLCVAKDSPSPCSPEKHSDITKKPESQCDPNEILCYGLCVAKDSPSPCSPEKHSDITKKPESQCNPNEILCYGLCVAKDSPSPCSPEKNSDITKKPESQCDPNEILCYGLCVAKDSPSLCSPEKHSDITKKPESQCNPNEILCYGLCVAKDSPSPCSPEKNSDITKKPESQCDPNEILCYGLCVAKDSPSPCSPEKHSDITKQPESQCEPNEILCYGLCVAKDSPSPCSPATHSVVADLTTPPPLKCDWIQFSCKESPVCISRSLLCDGAKDCPDGSDEGPDNCDTLACFDTEFMCASGSCILKTWKCDGDQDCNDASDEIDCGQ

Description

Involved in uptake of vitellogenin by endocytosis. Expression is regulated by the juvenile hormone analog, methoprene (in vitro).

Keywords

Calcium Disulfide bond EGF-like domain Endocytosis Glycoprotein Membrane Receptor Repeat Signal Transmembrane Transmembrane helix

Feature

chain Vitellogenin receptor

Uniprot

A0A2J7QQP4 A0A182QRH4 A0A1A9W8J7 A0A0M4ETD4 A0A1B0APB9 Q6X0I2 + More

Pubmed

15056367

EMBL

NEVH01012083 PNF30911.1 AXCN02001967 CP012528 ALC49752.1 JXJN01001301 + More
AY262832 AAP92450.1

Proteomes

UP000235965 UP000075886 UP000091820 UP000092553 UP000092460

PRIDE

Q6X0I2

Pfam

PF00057   Ldl_recept_a        + More
PF00058   Ldl_recept_b
PF07645   EGF_CA
PF12662   cEGF

Interpro

IPR000033   LDLR_classB_rpt        + More
IPR001881   EGF-like_Ca-bd_dom
IPR002172   LDrepeatLR_classA_rpt
IPR036055   LDL_receptor-like_sf
IPR009030   Growth_fac_rcpt_cys_sf
IPR018097   EGF_Ca-bd_CS
IPR013032   EGF-like_CS
IPR000742   EGF-like_dom
IPR011042   6-blade_b-propeller_TolB-like
IPR000152   EGF-type_Asp/Asn_hydroxyl_site
IPR023415   LDLR_class-A_CS
IPR026823   cEGF

SUPFAM

SSF57424 SSF57424 + More
SSF57184 SSF57184

Gene 3D

2.120.10.30 4.10.400.10

CDD

cd00112 LDLa

ProteinModelPortal

A0A2J7QQP4 A0A182QRH4 A0A1A9W8J7 A0A0M4ETD4 A0A1B0APB9 Q6X0I2 + More

PDB

4DG6 E-value=4.44172e-29, Score=323

KEGG

692651 no KO assigned | (RefSeq) Vgr; vitellogenin receptor

GO

GO:0005509 GO:0016021 GO:0006898 GO:0038024 GO:0005515 GO:0004190 GO:0006508 GO:0003676 GO:0016788 GO:0007165 GO:0005525 GO:0008033 GO:0016787

Subcellular location

Membrane

Length:

1102

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01538

Exp number, first 60 AAs:

0.00911

Total prob of N-in:

0.00082

outside

1 - 1102

Pi

251.446384

Theta

166.930672

Tajima's D

1.3479

CLR

0.034977

CSRT

0.747962601869906

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics