Gene

KWMTBOMO12177  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004221

Annotation

glucose-6-phosphate_isomerase_[Bombyx_mori]

Location

Bomo_Chr20(-):8809621-8825909      View in EpiBrowser

Full name

Glucose-6-phosphate isomerase      

Location in the cell

Cytoplasmic   Reliability : 3.639

CDS

ATGGAACCGAAAATTAATTTAAAGCAAGACGCAGCTTATCAAAAATTACAAGAATATTACAATGTAAACAGCACAAAAATTAATATGCTCCAACTTTTCCAACAAGATCGGGAGCGTTTCGAAAAGTTCAGCCTCTGTATCCCAACACCGAACGATGGAGACATCCTACTTGACTATTCCAAGAACCGTATCAACAGTGATGTTTTTAAGTTGCTCCTCGATCTCGCTAAGAGCAGAAATGTTGAACAAGCCAGAGATGCCATGTTCGCAGGTCAAAAGATAAACTTCACAGAAGACAGGGCAGTACTGCATATAGCTCTGCGTAACCGTCAGAACAAGCCTATCCTGGTGAACGGTAAGGATGTCAGCACTGATGTCAATGCGGTACTAGAACACATGAAGGAATTCTCCGATCAAGTAGTAAGCGGGCAATGGAAGGGGTATACGGGAAAAGCTATAACAGACGTGATCAACATTGGTATTGGAGGCTCAGATGTGGGTCCTCTCATGGTCACAGAAGCACTGAAGCCCTATGCTAATCATCTTAAGGTCCATTTCGTATCTAACATCGACGGCACCCACCTGGCTGAGGTCTTGAAGAAGCTGAACCCTGAGACAGCGCTGTTCATCATAGCATCCAAGACTTTCACCACACAAGAGACGATAACCAATGCGAGCTCAGCTAAGACGTGGTTCCTGGAATCCGCTAAGGATCCCTCGGCGGTGGCGAGACACTTCGTCGCTTTATCGACGAACGCCGAGAAGGTCACCGCGTTCGGTATCGACGCTAACAACATGTTCGGCTTCTGGGACTGGGTCGGGGGCAGATATTCGCTGTGGTCCGCGATCGGTCTGTCCATCTCGCTGTACATCGGACACGAAAACTTCGAGAAACTTCTGGACGGAGCCAATTTCATGGACCAGCACTTCGTCACCGCACCGCTGGAGAAGAATGCTCCCGTGATCTTAGCTCTGTTAGGAGTCTGGTACCACAATTTCTACGGAGCAGAGACCCATGCGCTGCTGCCTTACGATCAATATCTACACAGATTCGCAGCGTATTTCCAGCAGGGCGATATGGAGAGCAATGGCAAGTACGTGACGCGTTCAGGAGCCGAAGTGGAATACTCCACGGGGCCCATCGTGTGGGGCGAGCCCGGGACCAACGGACAGCACGCCTTCTACCAGCTCATACACCAGGGAACCAGATTGATTCCATGCGATTTCATCGCTCCAGCCCAAACTCACAATCCAATTTCGAATGGTGTTCACCACAAGATCCTTCTAGCTAATTTCTTGGCTCAAACCGAAGCCCTGATGAAGGGCAAGACAGCTGACGAGGCTAAAGCTGAGCTAGAGAAATCTGGTATGGCTCCGGAGGCAATAGACAAGATCCTTCCGCACAAGGTATTCAAAGGAAACCGGCCTACAAACTCTATTGTTCTGAAGAAGATCACTCCATTCACTTTAGGAGCACTTATTGCCATGTACGAACACAAGATCTTCACGCAAGGTGTGATCTGGGATATCAATTCATACGATCAATGGGGAGTTGAACTCGGCAAGCAATTGGCCAAGGCAATCGAGCCTGAGCTGCAGGGGACTGCAGCTGTGACCGGCCACGACGCTTCCACGAATGGACTCATTAACTTCCTCAAGAAGAACTTTTGA

Protein

MEPKINLKQDAAYQKLQEYYNVNSTKINMLQLFQQDRERFEKFSLCIPTPNDGDILLDYSKNRINSDVFKLLLDLAKSRNVEQARDAMFAGQKINFTEDRAVLHIALRNRQNKPILVNGKDVSTDVNAVLEHMKEFSDQVVSGQWKGYTGKAITDVINIGIGGSDVGPLMVTEALKPYANHLKVHFVSNIDGTHLAEVLKKLNPETALFIIASKTFTTQETITNASSAKTWFLESAKDPSAVARHFVALSTNAEKVTAFGIDANNMFGFWDWVGGRYSLWSAIGLSISLYIGHENFEKLLDGANFMDQHFVTAPLEKNAPVILALLGVWYHNFYGAETHALLPYDQYLHRFAAYFQQGDMESNGKYVTRSGAEVEYSTGPIVWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPAQTHNPISNGVHHKILLANFLAQTEALMKGKTADEAKAELEKSGMAPEAIDKILPHKVFKGNRPTNSIVLKKITPFTLGALIAMYEHKIFTQGVIWDINSYDQWGVELGKQLAKAIEPELQGTAAVTGHDASTNGLINFLKKNF

Catalytic Activity

aldehydo-D-glucose 6-phosphate = keto-D-fructose 6-phosphate

Similarity

Belongs to the GPI family.

Uniprot

Q2F5I6   H9J3Y2   Q2Q4Z1   C5I8Y2   C5I905   G9BZI8   + More
G9BZI3   C5I8Y4   Q2Q4Y6   G9BZI5   Q2Q4Z5   Q2F7Z2   C5I8Z2   A0A2H1V8Q8   C5I8X3   Q2Q4Z7   C5I8X0   C5I904   C5I902   C5I8X1   Q2Q4Z6   C5I900   C5I903   C5I8Z9   C5I8W3   C5I8X9   C5I8X8   C5I8Y5   C5I906   G9BZI7   Q2Q4Z9   C5I907   C5I8X4   G9BZJ0   C5I8X7   C5I8W2   C5I8X6   C5I8Y1   C5I8W5   H6TMR9   C5I8W6   C5I8Y3   C5I8W7   C5I8W9   H6TMR8   Q2Q4Y7   Q2Q4Z8   G9BZJ1   C5I8X5   Q2Q4Y8   Q2Q4Z0   C5I8Y0   C5I8W4   C5I8Z5   C5I8W8   G9BZI2   C5I901   C5I8Z3   G9BZI6   E3UKM3   G9BZI9   H6TMT1   C5I8Z4   C5I8Z8   C5I8Z7   H6TMQ3   C5I8Y8   D6BNT9   H6TMQ8   H6TMS5   H6TMQ6   H6TMR5   H6TMT2   C5I8Z0   H6TMR6   H6TMS2   H6TMR0   H6TMQ9   Q2Q4Z2   H6TMQ5   H6TMP9   Q2Q4Y9   H6TMS4   D2XVJ3   C5I8Y9   C5I8Y6   H6TMT0   C6FF88   D2XVG0   H6TMT5   H6TMR3   C6FFA4   C6FFA5   D2XVI5   D2XVJ1   H6TMQ0   H6TMR4   D2XVJ0   H6TMR1   H6TMQ7  

EC Number

5.3.1.9

Pubmed

19121390    16292000    19424742    22314051    19793833   

EMBL

DQ311437    ABD36381.1    BABH01040234    BABH01040235    DQ205071    FJ796737    + More
ABB76196.1    ACS27520.1    FJ796728    ACS27511.1    FJ796751    ACS27534.1    HQ717714    AEV89434.1    HQ717709    AEV89429.1    FJ796730    ACS27513.1    DQ205076    ABB76201.1    HQ717711    AEV89431.1    DQ205067    ABB76192.1    DQ205092    ABB00833.1    FJ796738    ACS27521.1    ODYU01001261    SOQ37230.1    FJ796719    ACS27502.1    DQ205065    FJ796718    ABB76190.1    ACS27501.1    FJ796716    ACS27499.1    FJ796750    ACS27533.1    FJ796748    ACS27531.1    FJ796717    ACS27500.1    DQ205066    ABB76191.1    FJ796746    ACS27529.1    FJ796749    ACS27532.1    FJ796745    ACS27528.1    FJ796709    ACS27492.1    FJ796725    HQ717710    ACS27508.1    AEV89430.1    FJ796724    ACS27507.1    FJ796731    ACS27514.1    FJ796752    ACS27535.1    HQ717713    AEV89433.1    DQ205063    ABB76188.1    FJ796753    ACS27536.1    FJ796720    ACS27503.1    HQ717716    AEV89436.1    FJ796723    ACS27506.1    FJ796708    ACS27491.1    FJ796722    ACS27505.1    FJ796727    ACS27510.1    FJ796711    ACS27494.1    JN191731    AFA51145.1    FJ796712    ACS27495.1    FJ796729    ACS27512.1    FJ796713    ACS27496.1    FJ796715    ACS27498.1    JN191730    AFA51144.1    DQ205075    ABB76200.1    DQ205064    ABB76189.1    HQ717717    AEV89437.1    FJ796721    ACS27504.1    DQ205074    ABB76199.1    DQ205072    ABB76197.1    FJ796726    ACS27509.1    FJ796710    ACS27493.1    FJ796741    FJ796742    ACS27524.1    FJ796714    ACS27497.1    HQ717708    AEV89428.1    FJ796747    ACS27530.1    FJ796739    ACS27522.1    HQ717712    AEV89432.1    HM449897    ADO33032.1    HQ717715    AEV89435.1    JN191743    AFA51157.1    FJ796740    ACS27523.1    FJ796744    ACS27527.1    FJ796743    ACS27526.1    JN191715    JN191716    AFA51129.1    FJ796734    ACS27517.1    FJ793040    ACV97159.1    JN191720    AFA51134.1    JN191737    AFA51151.1    JN191718    AFA51132.1    JN191727    AFA51141.1    JN191744    JN191745    JN191746    AFA51158.1    FJ796736    ACS27519.1    JN191728    AFA51142.1    JN191734    AFA51148.1    JN191722    AFA51136.1    JN191721    AFA51135.1    DQ205070    ABB76195.1    JN191717    AFA51131.1    JN191711    AFA51125.1    DQ205073    ABB76198.1    JN191736    AFA51150.1    GU263977    ADB11225.1    FJ796735    ACS27518.1    FJ796732    ACS27515.1    JN191742    AFA51156.1    EU888447    ACF57681.1    GU263944    ADB11192.1    JN191747    AFA51161.1    JN191725    AFA51139.1    EU888463    EU888465    EU888470    GU263964    GU263965    GU263966    GU263967    GU263968    GU263970    GU263971    GU263972    GU263973    GU263976    ACF57697.1    ADB11212.1    ADB11214.1    ADB11215.1    ADB11216.1    ADB11218.1    ADB11219.1    ADB11220.1    ADB11224.1    EU888464    GU263937    GU263938    GU263939    GU263940    GU263941    ACF57698.1    ADB11185.1    ADB11187.1    ADB11188.1    ADB11189.1    GU263969    ADB11217.1    GU263975    ADB11223.1    JN191712    AFA51126.1    JN191726    AFA51140.1    GU263974    ADB11222.1    JN191723    AFA51137.1    JN191719    AFA51133.1   

Proteomes

UP000005204   

PRIDE

Q2F5I6    H9J3Y2   

Pfam

PF00342   PGI

Interpro

IPR035482   SIS_PGI_2        + More
IPR035476   SIS_PGI_1       
IPR023096   G6P_Isomerase_C       
IPR001672   G6P_Isomerase       
IPR018189   Phosphoglucose_isomerase_CS       

Gene 3D

1.10.1390.10    

CDD

cd05016  SIS_PGI_2
cd05015  SIS_PGI_1

ProteinModelPortal

Q2F5I6   H9J3Y2   Q2Q4Z1   C5I8Y2   C5I905   G9BZI8   + More
G9BZI3   C5I8Y4   Q2Q4Y6   G9BZI5   Q2Q4Z5   Q2F7Z2   C5I8Z2   A0A2H1V8Q8   C5I8X3   Q2Q4Z7   C5I8X0   C5I904   C5I902   C5I8X1   Q2Q4Z6   C5I900   C5I903   C5I8Z9   C5I8W3   C5I8X9   C5I8X8   C5I8Y5   C5I906   G9BZI7   Q2Q4Z9   C5I907   C5I8X4   G9BZJ0   C5I8X7   C5I8W2   C5I8X6   C5I8Y1   C5I8W5   H6TMR9   C5I8W6   C5I8Y3   C5I8W7   C5I8W9   H6TMR8   Q2Q4Y7   Q2Q4Z8   G9BZJ1   C5I8X5   Q2Q4Y8   Q2Q4Z0   C5I8Y0   C5I8W4   C5I8Z5   C5I8W8   G9BZI2   C5I901   C5I8Z3   G9BZI6   E3UKM3   G9BZI9   H6TMT1   C5I8Z4   C5I8Z8   C5I8Z7   H6TMQ3   C5I8Y8   D6BNT9   H6TMQ8   H6TMS5   H6TMQ6   H6TMR5   H6TMT2   C5I8Z0   H6TMR6   H6TMS2   H6TMR0   H6TMQ9   Q2Q4Z2   H6TMQ5   H6TMP9   Q2Q4Y9   H6TMS4   D2XVJ3   C5I8Y9   C5I8Y6   H6TMT0   C6FF88   D2XVG0   H6TMT5   H6TMR3   C6FFA4   C6FFA5   D2XVI5   D2XVJ1   H6TMQ0   H6TMR4   D2XVJ0   H6TMR1   H6TMQ7  

PDB

4WMJ     E-value=0,     Score=2649

KEGG

778462    K01810 glucose-6-phosphate isomerase [EC:5.3.1.9] | (RefSeq) glucose-6-phosphate isomerase

PATHWAY

00010    Glycolysis / Gluconeogenesis - Bombyx mori (domestic silkworm)
00030    Pentose phosphate pathway - Bombyx mori (domestic silkworm)
00500    Starch and sucrose metabolism - Bombyx mori (domestic silkworm)
00520    Amino sugar and nucleotide sugar metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)

GO

GO:0006096   GO:0004347   GO:0006094   GO:0003824   GO:0016788   GO:0007165   GO:0005525   GO:0008033   GO:0003676   GO:0016787  

PANTHER

PTHR11469  

Length:

556

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.23281

Exp number, first 60 AAs:

0.00025

Total prob of N-in:

0.00816

outside

1  -  556

 

 

Pi

180.207019

Theta

174.484531

Tajima's D

0.989326

CLR

0.21849

CSRT

0.661366931653417

Interpretation

Uncertain