Gene

KWMTBOMO12166  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014059

Annotation

PREDICTED:_NADH_dehydrogenase_[ubiquinone]_1_alpha_subcomplex_subunit_10?_mitochondrial_[Papilio_polytes]

Location

Bomo_Chr20(-):8636299-8640956      View in EpiBrowser

Full name

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial      

Alternative Name

Complex I-42kD
NADH-ubiquinone oxidoreductase 42 kDa subunit

Location in the cell

Cytoplasmic   Reliability : 1.597 Mitochondrial   Reliability : 1.615

CDS

ATGGCTACTCTCGTCAGAACAGCTGTAATTAAAGTTATCAGCCCAACTCAGGGTACAAAAATAGCAGCATGTACGTTTGTACAAAATAGGAATATCTCCGGGCGGGCCATGCGGGAAGCGCTACCACCTCCTCCACCGAAACCTGCACCCTTTGACTATGTGAACAAGGACTACACTTGGTTGCGCAGCTTAATCGACCGCACGACCCACAGGTTTGATGATAACAGCAAAGTGATAATCGTGGAAGGGCCGGTAGCTGCTGGTAAGACCGCCTTTGCAGCCTCCCTAGCCGATGACTTGGGTATGAAGCATTTCCCCGAAGCTAACATGGATTTGCACTATATTCGTCCGAACGGCGTCGACTTGAGGTCCTTCGACGACCAAGTACCCGAGGACACTAGGACCTTTGACCATGTTAATTTCAATCAGAATCCTAACCATCGCTTGGCTGCAAACTTCCAAATAATGATGTATGTGGCCCGGTACAGTCAGTATATTGATGCTTTGGCACACCTGTTCAATACTGGCCAAGGAATTGTGTTGGAGAGGTCCCCTTACTCTGACTTTGTATTCTTGGAAGCTATGTATTCTCAGAAATTCTTGAGTAAGGCAGTCAGGTCAACTTACTATGAGCTGCGAGAAAACACAATTGAGGAGCTAATGCGTCCACATCTAGTTATTTATCTGGATCTTCCTGTTTCCAAGGTTCAAGAAGCTATTAAAAAACGTGCTCTCAGTCACGAGGTGACCAGCAAAGCTCTCACACCGGCCTTCCTGACTGAAATTGAGAAGCAGTACAAAAACAAGTATCTGAGAGATATCGCCACTCATGCAGAGCTGCTCGTGTACGACTGGACCGGAGGAGGTGAAGTCGAAGTGGTCGTCGAGGACATAGAGCGACTGAACTTCGACCAGTATACGGAGCGTGAAGAGCCCAAGATGAAGGACTGGCGTTTGCCTCGCGAAGTGGACTGGGCCGACCAGCGCGCGCTCTACACGAACCAGAAGCACTTGCTGATGAATCTGCTCGCCATCCCCAAACTGGACATACCGGAGCTGATAACTAGCGCCGAGGACTGTTACGAGAGAGAAAAGGTTATTTCTGCTCACCCAGCCTTCCGTTACGAACTGGGATACGCGCCAGGCGAATCTGTGACCTTCAAGAACAAGCTGCCCAAATACCACGAGTACATATAG

Protein

MATLVRTAVIKVISPTQGTKIAACTFVQNRNISGRAMREALPPPPPKPAPFDYVNKDYTWLRSLIDRTTHRFDDNSKVIIVEGPVAAGKTAFAASLADDLGMKHFPEANMDLHYIRPNGVDLRSFDDQVPEDTRTFDHVNFNQNPNHRLAANFQIMMYVARYSQYIDALAHLFNTGQGIVLERSPYSDFVFLEAMYSQKFLSKAVRSTYYELRENTIEELMRPHLVIYLDLPVSKVQEAIKKRALSHEVTSKALTPAFLTEIEKQYKNKYLRDIATHAELLVYDWTGGGEVEVVVEDIERLNFDQYTEREEPKMKDWRLPREVDWADQRALYTNQKHLLMNLLAIPKLDIPELITSAEDCYEREKVISAHPAFRYELGYAPGESVTFKNKLPKYHEYI

Description

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Cofactor

FAD

Subunit

Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction (By similarity).

Similarity

Belongs to the complex I NDUFA10 subunit family.

Keywords

Complete proteome   Electron transport   FAD   Flavoprotein   Mitochondrion   Reference proteome   Respiratory chain   Transit peptide   Transport  

Feature

chain  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

Uniprot

H9JWZ4   A0A2W1BFM8   S4PPT2   I4DJN1   A0A2A4J4B3   A0A2H1VMP4   + More
A0A3S2LPC2   A0A212F375   A0A220K8N4   A0A0L7L2W1   A0A0N1IKH2   A0A0K8TSV4   B4NHR3   A0A1B6I241   B3LVL1   A0A1W4VQ24   B4M0N2   A0A0L0C5X1   B4K6L1   A0A1L8EDU1   A0A1L8EDU6   A0A1J1ICX8   A0A0M4F600   B4QZD1   B4HM81   B4JRL6   B3P7P1   A0A034W901   Q297T7   B0WW92   A4V383   P91929   A0A0K8VIR8   A0A1B6LQC9   B4PLJ6   A0A1I8Q2W2   A0A182M9V2   A0A3B0JFE9   B4G309   A0A182WDL5   A0A182YAZ9   D3TLY4   A0A067R4C9   A0A2M3Z1B4   Q7QHC7   A0A182TDY3   A0A2J7QKF4   A0A2M4BRB2   T1PBJ6   A0A2M3ZG26   W8BR54   A0A1Q3FH78   A0A1I8MID9   A0A182X5Q2   W5JP72   A0A1A9YQF0   A0A182VAU3   T1E8C6   A0A182HW95   A0A1B0AY20   A0A182FW35   A0A182KL06   D1ZZE8   A0A182NZQ0   A0A182Q7B1   A0A2M4A7D5   A0A182T4L6   A0A182N286   A0A1B0A1A9   A0A182RW40   A0A023F1W2   A0A084WM05   A0A182JX01   A0A224XRJ6   A0A1L8E0J4   A0A1A9VWM7   U5EVK8   A0A023ERK6   V5G650   A0A182G813   Q1HQV6   A0A182JDF2   A0A1B6FVR3   A0A1B0D7X3   A0A1A9WWW0   A0A1B6DH01   A0A3R7SKG8   A0A0T6B1G8   T1HTY7   A0A1B0CQN1   A0A1B0D3Z1   J3JVZ9   U4UML3   N6U8T6   J9K3B7   A0A170ZEA3   A0A2H8U1Y7   A0A146ME71   A0A1W4XC65  

Pubmed

19121390    28756777    23622113    22651552    26354079    22118469    + More
28630352    26227816    26369729    17994087    26108605    25348373    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12537569    10071211    17550304    25244985    20353571    24845553    12364791    14747013    17210077    24495485    25315136    20920257    23761445    20966253    18362917    19820115    25474469    24438588    24945155    26483478    17204158    17510324    22516182    23537049    26823975   

EMBL

BABH01041746    KZ150228    PZC72027.1    GAIX01000027    JAA92533.1    AK401499    + More
KQ459053    BAM18121.1    KPJ04189.1    NWSH01003461    PCG66253.1    ODYU01003385    SOQ42077.1    RSAL01000495    RVE41533.1    AGBW02010605    OWR48187.1    MF319745    ASJ26459.1    JTDY01003379    KOB69646.1    LADJ01000094    KPJ20830.1    GDAI01000149    JAI17454.1    CH964272    EDW84673.1    GECU01026713    JAS80993.1    CH902617    EDV42581.1    CH940650    EDW67324.1    JRES01000955    KNC26814.1    CH933806    EDW16311.1    GFDG01001973    JAV16826.1    GFDG01001974    JAV16825.1    CVRI01000047    CRK98059.1    CP012526    ALC47400.1    CM000364    EDX13867.1    CH480815    EDW43129.1    CH916373    EDV94406.1    CH954182    EDV54202.1    GAKP01008179    GAKP01008178    GAKP01008177    GAKP01008175    GAKP01008173    JAC50777.1    CM000070    EAL28118.1    DS232140    EDS35924.1    AE014297    AAN13899.1    AY051764    Y10911    GDHF01031881    GDHF01027384    GDHF01021211    GDHF01013561    GDHF01011070    GDHF01001202    JAI20433.1    JAI24930.1    JAI31103.1    JAI38753.1    JAI41244.1    JAI51112.1    GEBQ01014124    JAT25853.1    CM000160    EDW97945.1    AXCM01004806    OUUW01000005    SPP81057.1    CH479179    EDW24204.1    CCAG010001866    EZ422436    ADD18712.1    KK852902    KDR14073.1    GGFM01001520    MBW22271.1    AAAB01008816    EAA05289.4    NEVH01013262    PNF29067.1    GGFJ01006167    MBW55308.1    KA646141    AFP60770.1    GGFM01006731    MBW27482.1    GAMC01005003    JAC01553.1    GFDL01008137    JAV26908.1    ADMH02000909    ETN64695.1    GAMD01002888    JAA98702.1    APCN01001478    JXJN01005495    KQ971338    EFA02878.1    AXCN02001731    GGFK01003331    MBW36652.1    GBBI01003389    JAC15323.1    ATLV01024337    KE525351    KFB51249.1    GFTR01005827    JAW10599.1    GFDF01001863    JAV12221.1    GANO01001834    JAB58037.1    GAPW01001785    JAC11813.1    GALX01002921    JAB65545.1    JXUM01151271    KQ571179    KXJ68229.1    DQ440338    CH477951    ABF18371.1    EAT34841.1    GECZ01015530    JAS54239.1    AJVK01032324    GEDC01012329    JAS24969.1    QCYY01003201    ROT64718.1    LJIG01016233    KRT81217.1    ACPB03011673    AJWK01023776    AJVK01023820    AJVK01023821    BT127417    AEE62379.1    KB632278    ERL91265.1    APGK01035397    KB740924    ENN78065.1    ABLF02029434    GEMB01002306    JAS00875.1    GFXV01008107    MBW19912.1    GDHC01001769    JAQ16860.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000283053    UP000007151    UP000037510    + More
UP000053240    UP000007798    UP000007801    UP000192221    UP000008792    UP000037069    UP000009192    UP000183832    UP000092553    UP000000304    UP000001292    UP000001070    UP000008711    UP000001819    UP000002320    UP000000803    UP000002282    UP000095300    UP000075883    UP000268350    UP000008744    UP000075920    UP000076408    UP000092444    UP000027135    UP000007062    UP000075902    UP000235965    UP000095301    UP000076407    UP000000673    UP000092443    UP000075903    UP000075840    UP000092460    UP000069272    UP000075882    UP000007266    UP000075885    UP000075886    UP000075901    UP000075884    UP000092445    UP000075900    UP000030765    UP000075881    UP000078200    UP000069940    UP000249989    UP000008820    UP000075880    UP000092462    UP000091820    UP000283509    UP000015103    UP000092461    UP000030742    UP000019118    UP000007819    UP000192223   

PRIDE

H9JWZ4    A4V383    P91929   

Pfam

PF01712   dNK        + More
PF02724   CDC45
PF01612   DNA_pol_A_exo1

Interpro

IPR027417   P-loop_NTPase        + More
IPR031314   DNK_dom       
IPR015828   NDUFA10       
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       
IPR036397   RNaseH_sf       
IPR003874   CDC45       
IPR012337   RNaseH-like_sf       
IPR002562   3'-5'_exonuclease_dom       

SUPFAM

SSF52540   SSF52540        + More
SSF50978   SSF50978       
SSF53098   SSF53098       

Gene 3D

2.130.10.10     3.30.420.10    

CDD

cd02030  NDUO42

ProteinModelPortal

H9JWZ4   A0A2W1BFM8   S4PPT2   I4DJN1   A0A2A4J4B3   A0A2H1VMP4   + More
A0A3S2LPC2   A0A212F375   A0A220K8N4   A0A0L7L2W1   A0A0N1IKH2   A0A0K8TSV4   B4NHR3   A0A1B6I241   B3LVL1   A0A1W4VQ24   B4M0N2   A0A0L0C5X1   B4K6L1   A0A1L8EDU1   A0A1L8EDU6   A0A1J1ICX8   A0A0M4F600   B4QZD1   B4HM81   B4JRL6   B3P7P1   A0A034W901   Q297T7   B0WW92   A4V383   P91929   A0A0K8VIR8   A0A1B6LQC9   B4PLJ6   A0A1I8Q2W2   A0A182M9V2   A0A3B0JFE9   B4G309   A0A182WDL5   A0A182YAZ9   D3TLY4   A0A067R4C9   A0A2M3Z1B4   Q7QHC7   A0A182TDY3   A0A2J7QKF4   A0A2M4BRB2   T1PBJ6   A0A2M3ZG26   W8BR54   A0A1Q3FH78   A0A1I8MID9   A0A182X5Q2   W5JP72   A0A1A9YQF0   A0A182VAU3   T1E8C6   A0A182HW95   A0A1B0AY20   A0A182FW35   A0A182KL06   D1ZZE8   A0A182NZQ0   A0A182Q7B1   A0A2M4A7D5   A0A182T4L6   A0A182N286   A0A1B0A1A9   A0A182RW40   A0A023F1W2   A0A084WM05   A0A182JX01   A0A224XRJ6   A0A1L8E0J4   A0A1A9VWM7   U5EVK8   A0A023ERK6   V5G650   A0A182G813   Q1HQV6   A0A182JDF2   A0A1B6FVR3   A0A1B0D7X3   A0A1A9WWW0   A0A1B6DH01   A0A3R7SKG8   A0A0T6B1G8   T1HTY7   A0A1B0CQN1   A0A1B0D3Z1   J3JVZ9   U4UML3   N6U8T6   J9K3B7   A0A170ZEA3   A0A2H8U1Y7   A0A146ME71   A0A1W4XC65  

PDB

5LNK     E-value=1.12432e-41,     Score=427

KEGG

101745480    K03954 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 | (RefSeq) NADH dehydrogenase [

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005759   GO:0006120   GO:0005747   GO:0055114   GO:0070469   GO:0016491   GO:0003954   GO:0005739   GO:0008137   GO:0005737   GO:0016301   GO:0016021   GO:0006270   GO:0003676   GO:0008408  

PANTHER

PTHR10507  

Subcellular location

Mitochondrion matrix  

Length:

398

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.10427

Exp number, first 60 AAs:

0.01523

Total prob of N-in:

0.01888

outside

1  -  398

 

 

Pi

179.250167

Theta

141.394781

Tajima's D

1.290341

CLR

0

CSRT

0.739113044347783

Interpretation

Uncertain