Gene

KWMTBOMO12112

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr20(+):7736585-7739172      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.192 PlasmaMembrane   Reliability : 1.295

CDS

ATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATTGCTTCCGTTTAGTCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCGTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAGCAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGCCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATCCGTGCGTACGATAGCTCGTACTCTCAAATCGGATACGGTAGTAACCATGCCCCCCTCGAAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCTGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTTAG

Protein

MVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPLLPFSPDSIPSPQDTAEAIDIVTSHITSTLDRSSKQVVAEDFLHRFKLPDDIRELLRAKNASIRAYDSSYSQIGYGSNHAPLEGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMIC

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   D7EM17   X1WNI2   J9LC21   K7IN67   A0A023EYS8   A0A2S2QEE0   A0A2S2PPK8   X1WZH0   X1WXR6   J9JS95   J9LFC9   A0A023EZE6   J9KPF1   A0A2S2NJB5   A0A224XI99   A0A2S2N814   A0A2S2PJG2   A0A2S2PA10   A0A224XB44   X1WIX8   A0A224X7Z3   A0A2J7R7D0   A0A224X6S1   A0A2H8TF37   A0A2S2NGV8   A0A224X6T4   A0A2J7RMG0   A0A224XF24   A0A224X6U5   A0A2S2NPJ7   A0A224X6W2   A0A2S2N6Q7   A0A224X746   A0A2S2P6S3   J9KSK5   A0A2S2P698   A0A2S2Q383   A0A087UCW3   A0A0H3UA66   Q95SX7   X1WXE6   A0A0V0G5B6   A0A1Y1KFR3   A0A2S2P7B2   A0A087U3K8   J9LK81   A0A224XIB0   A0A087UGF5   A0A232ENU1   X1WTA1   A0A2S2P6C4   A0A2M4BD67   A0A2S2PBB4   A0A2H8TKI9   A0A069DX78   A0A2S2PHL7   A0A2M4BDV6   A0A2S2NKC3   A0A224X6R6   A0A2S2Q352   A0A1Q3G5J4   A0A2S2PUS3   X1XGU0  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
20075255    25474469    26812285    7753626    12537569    28648823    26334808   

EMBL

U07847    AAA17752.1    AB055391    BAB21761.1    AB018558    BAA76304.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ973412    EFA12510.2    ABLF02008153    ABLF02008462    ABLF02008464    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GBBI01004395    JAC14317.1    GGMS01006359    MBY75562.1    GGMR01018716    MBY31335.1    ABLF02034467    ABLF02008605    ABLF02008608    ABLF02008609    ABLF02008610    ABLF02017023    ABLF02028535    ABLF02028545    ABLF02023911    GBBI01004571    JAC14141.1    ABLF02041767    GGMR01004661    MBY17280.1    GFTR01008256    JAW08170.1    GGMR01000676    MBY13295.1    GGMR01016905    MBY29524.1    GGMR01013409    MBY26028.1    GFTR01008262    JAW08164.1    ABLF02017874    ABLF02027031    GFTR01007929    JAW08497.1    NEVH01006736    PNF36716.1    GFTR01008271    JAW08155.1    GFXV01000908    MBW12713.1    GGMR01003407    MBY16026.1    GFTR01008261    JAW08165.1    NEVH01002556    PNF42024.1    GFTR01008038    JAW08388.1    GFTR01008251    JAW08175.1    GGMR01006491    MBY19110.1    GFTR01008260    JAW08166.1    GGMR01000226    MBY12845.1    GFTR01008151    JAW08275.1    GGMR01012443    MBY25062.1    ABLF02014118    ABLF02014121    ABLF02054790    GGMR01012305    MBY24924.1    GGMS01002992    MBY72195.1    KK119261    KFM75202.1    KF280391    AIE77315.1    AY060438    AAL25477.1    ABLF02016634    GECL01003538    JAP02586.1    GEZM01084969    JAV60363.1    GGMR01012676    MBY25295.1    KK118005    KFM71947.1    ABLF02023551    ABLF02023561    GFTR01008246    JAW08180.1    KK119692    KFM76444.1    NNAY01003095    OXU19992.1    ABLF02037660    GGMR01012283    MBY24902.1    GGFJ01001858    MBW50999.1    GGMR01014053    MBY26672.1    GFXV01002840    MBW14645.1    GBGD01000389    JAC88500.1    GGMR01016296    MBY28915.1    GGFJ01001857    MBW50998.1    GGMR01005022    MBY17641.1    GFTR01008269    JAW08157.1    GGMS01002955    MBY72158.1    GFDL01000006    JAV35039.1    GGMR01020516    MBY33135.1    ABLF02055645   

Proteomes

UP000053268    UP000007266    UP000007819    UP000002358    UP000235965    UP000054359    + More
UP000215335   

PRIDE

Q93137    Q9BPQ0    Q9XXW0    Q95SX7   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF07727   RVT_2
PF10551   MULE

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       
IPR013083   Znf_RING/FYVE/PHD       
IPR018289   MULE_transposase_dom       
IPR036397   RNaseH_sf       
IPR012337   RNaseH-like_sf       

SUPFAM

SSF56219   SSF56219        + More
SSF53098   SSF53098       

Gene 3D

3.60.10.10     3.30.40.10     3.30.420.10    

ProteinModelPortal

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   D7EM17   X1WNI2   J9LC21   K7IN67   A0A023EYS8   A0A2S2QEE0   A0A2S2PPK8   X1WZH0   X1WXR6   J9JS95   J9LFC9   A0A023EZE6   J9KPF1   A0A2S2NJB5   A0A224XI99   A0A2S2N814   A0A2S2PJG2   A0A2S2PA10   A0A224XB44   X1WIX8   A0A224X7Z3   A0A2J7R7D0   A0A224X6S1   A0A2H8TF37   A0A2S2NGV8   A0A224X6T4   A0A2J7RMG0   A0A224XF24   A0A224X6U5   A0A2S2NPJ7   A0A224X6W2   A0A2S2N6Q7   A0A224X746   A0A2S2P6S3   J9KSK5   A0A2S2P698   A0A2S2Q383   A0A087UCW3   A0A0H3UA66   Q95SX7   X1WXE6   A0A0V0G5B6   A0A1Y1KFR3   A0A2S2P7B2   A0A087U3K8   J9LK81   A0A224XIB0   A0A087UGF5   A0A232ENU1   X1WTA1   A0A2S2P6C4   A0A2M4BD67   A0A2S2PBB4   A0A2H8TKI9   A0A069DX78   A0A2S2PHL7   A0A2M4BDV6   A0A2S2NKC3   A0A224X6R6   A0A2S2Q352   A0A1Q3G5J4   A0A2S2PUS3   X1XGU0  

KEGG

101745053    no KO assigned | (RefSeq) uncharacterized LOC101745053

GO

GO:0003964   GO:0004519   GO:0006313   GO:0003676  

Length:

692

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.74234000000002

Exp number, first 60 AAs:

0.05422

Total prob of N-in:

0.05693

outside

1  -  692

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

774.224729

CSRT

0

Interpretation

Uncertain