Gene
KWMTBOMO12104
Pre Gene Modal
BGIBMGA004344
Annotation
G_protein_alpha_S_subunit_Gs1_[Bombyx_mori]
Full name
Guanine nucleotide-binding protein G(s) subunit alpha
+ More
G protein alpha s subunit
G protein alpha s subunit
Alternative Name
Adenylate cyclase-stimulating G alpha protein
Guanine nucleotide-binding protein G(s) subunit alpha
Guanine nucleotide-binding protein G(s) subunit alpha
Location in the cell
Nuclear Reliability : 3.47
Sequence
CDS
ATGGGTTGCTTCGGGTCACCGGGCGGCAAGAGCAGCGAGGGCGACGACATCAAGAAACAAAAGAGACGCAGCGATGCCATCACCAGGCAGCTGCAGAAGGATAAACAGTTGTATCGGGCGACGCACCGGCTGCTCCTGCTGGGCGCCGGCGAGTCCGGCAAGTCGACGATCGTGAAGCAGATGCGCATCTTGCATGTCAACGGCTTCTCCGACAAGGAGCGCAAGGAGAAGATCGAGGACATCAAGAAGAACATCCGCGATGCTATACTCACAATCACGGGTGCAATGAGTACCCTGACTCCTCCGATTCCACTCGAGAAGCAGGAGAACAAAGTACGCGTCGATTACATTCAGGACGTGGCGTCGCAGCCGGACTTCGACTACCCTTCGGAGTTCTACGAGCACACGGAGGCGCTGTGGAAGGACCAGGGCGTGCAGCGCACCTACGAGCGCAGCAACGAGTACCAGCTCATCGACTGCGCGAAATATTTCTTGGATAAAGTTCACATAATAAAGCAGGCGGACTACACGCCCACCGAACAGGACATCCTGCGCTGCCGAGTCCTCACCTCCGGGATATTCGAGACGCAGTTCGTCGTGGACAAAGTCAATTTCCACATGTTCGACGTGGGCGGGCAACGTGACGAGCGCCGTAAGTGGATCCAGTGCTTCAATGACGTGACGGCCATCATCTTCGTGACGGCCTGCTCCTCCTACAACATGGTGCTGCGCGAGGACCCCACGCAGAACCGGCTGCGCGAGTCTCTGGAACTGTTCAAGAGCATCTGGAACAACCGGTGGCTGCGGACCATCTCCGTCATCCTGTTCCTCAACAAGCAGGACCTGCTCGCCGAGAAGGTGCTGGCGGGGAAGTCCCGGCTCGAGGACTACTTCCAGGAGTTCGCCCGTTACCAGACCCCGCCTGATGCTGTGCCCGACGCCAAGGACCATCCCGAGGTGTCCCGCGCCAAGTACTTCATACGCGATGAGTTTCTGCGCATAAGTACGGCCAGCGGCGACGGTAAGCACTACTGCTACCCGCACTTCACGTGCGCTGTCGACACGGAGAACATCAAGCGCGTGTTCAACGACTGCCGCGACATCATCCAGCGCATGCACCTGCGCCAGTACGAGCTGCTCTAA
Protein
MGCFGSPGGKSSEGDDIKKQKRRSDAITRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVNGFSDKERKEKIEDIKKNIRDAILTITGAMSTLTPPIPLEKQENKVRVDYIQDVASQPDFDYPSEFYEHTEALWKDQGVQRTYERSNEYQLIDCAKYFLDKVHIIKQADYTPTEQDILRCRVLTSGIFETQFVVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLELFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSRLEDYFQEFARYQTPPDAVPDAKDHPEVSRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL
Summary
Description
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase. Participates in olfactory signal transduction.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase (By similarity).
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase (By similarity).
Subunit
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Similarity
Belongs to the G-alpha family. G(s) subfamily.
Keywords
Complete proteome
GTP-binding
Lipoprotein
Magnesium
Metal-binding
Nucleotide-binding
Olfaction
Palmitate
Reference proteome
Sensory transduction
Transducer
Alternative splicing
Feature
chain Guanine nucleotide-binding protein G(s) subunit alpha
splice variant In isoform A.
splice variant In isoform A.
Uniprot
A4UIH0
A0A194Q5I1
A0A0N0PEF5
A0A3S2LVU8
A0A2A4K4W8
A0A212ELI8
+ More
H9J4A5 H9J430 A0A1W7R6Z0 Q17E14 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 B0WHZ7 A0A182RSW4 A0A023ESA6 A0A182YC99 A0A182P1E8 A0A182HPK4 Q7PD79 A0A182M2F4 A0A1Q3F6P3 A0A182WD25 U5EXH7 A0A1I8MH09 A0A1L8ED71 A0A182X073 A0A1B0F9I9 A0A1A9V624 A0A182JGA6 A0A1J1I2Y7 A0A182KBH2 A0A1A9YJN9 A0A1B0ARM1 A0A182UB20 A0A1A9ZRE3 A0A1I8PIV9 T1E238 A0A1A9WAB9 A0A336LTA6 W8BZ77 A4UIH1 A0A1W4WR40 A0A0A1X9B5 A0A1L8DMF1 B4MRN1 A0A0M4E7G2 A0A0K8UX10 A0A034WSM6 A0A1W4ULJ8 A0A2W1BNU2 B4GCZ3 B4KMB8 B4LNZ7 Q292P9 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A0R1DX90 B3MCN0 B4J653 A0A1Y1N8F9 A0A1B6CHJ4 D6WRY4 B4PAA4 B4I8X0 B4QBE9 A0A1W4V0L9 B3NQ28 P20354 A0A0R3NL08 A0A0P9BX57 A0A224YZY8 A0A131YWJ3 A0A1B6KHH6 L7MG91 A0A310SVF7 A0A131XB20 A0A2A3EDR2 A0A087ZZ43 A0A1B6I6U4 A0A154PCG4 V5HXV0 B7PTW2 A0A1B6FY21 A0A067QXK2 A0A026W548 A0A131XRZ4 A0A2S2Q6Y1 A0A0L7RE20 A0A2H8TKC5 J9JJY9 A0A2S2N996 E0W0E0 A0A0C9QS92 A0A0P6ASZ2 A0A1V9XBE6 A0A293MDF1
H9J4A5 H9J430 A0A1W7R6Z0 Q17E14 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 B0WHZ7 A0A182RSW4 A0A023ESA6 A0A182YC99 A0A182P1E8 A0A182HPK4 Q7PD79 A0A182M2F4 A0A1Q3F6P3 A0A182WD25 U5EXH7 A0A1I8MH09 A0A1L8ED71 A0A182X073 A0A1B0F9I9 A0A1A9V624 A0A182JGA6 A0A1J1I2Y7 A0A182KBH2 A0A1A9YJN9 A0A1B0ARM1 A0A182UB20 A0A1A9ZRE3 A0A1I8PIV9 T1E238 A0A1A9WAB9 A0A336LTA6 W8BZ77 A4UIH1 A0A1W4WR40 A0A0A1X9B5 A0A1L8DMF1 B4MRN1 A0A0M4E7G2 A0A0K8UX10 A0A034WSM6 A0A1W4ULJ8 A0A2W1BNU2 B4GCZ3 B4KMB8 B4LNZ7 Q292P9 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A0R1DX90 B3MCN0 B4J653 A0A1Y1N8F9 A0A1B6CHJ4 D6WRY4 B4PAA4 B4I8X0 B4QBE9 A0A1W4V0L9 B3NQ28 P20354 A0A0R3NL08 A0A0P9BX57 A0A224YZY8 A0A131YWJ3 A0A1B6KHH6 L7MG91 A0A310SVF7 A0A131XB20 A0A2A3EDR2 A0A087ZZ43 A0A1B6I6U4 A0A154PCG4 V5HXV0 B7PTW2 A0A1B6FY21 A0A067QXK2 A0A026W548 A0A131XRZ4 A0A2S2Q6Y1 A0A0L7RE20 A0A2H8TKC5 J9JJY9 A0A2S2N996 E0W0E0 A0A0C9QS92 A0A0P6ASZ2 A0A1V9XBE6 A0A293MDF1
Pubmed
17449058
26354079
22118469
19121390
17510324
20920257
+ More
23761445 24945155 25244985 17029251 12364791 25315136 24330624 24495485 25830018 17994087 25348373 28756777 18057021 15632085 2498884 2106072 10731132 12537572 12537569 12537568 12537573 12537574 16110336 17569856 17569867 22936249 17550304 28004739 18362917 19820115 23185243 28797301 26830274 25576852 28049606 25765539 24845553 24508170 30249741 20566863 28327890
23761445 24945155 25244985 17029251 12364791 25315136 24330624 24495485 25830018 17994087 25348373 28756777 18057021 15632085 2498884 2106072 10731132 12537572 12537569 12537568 12537573 12537574 16110336 17569856 17569867 22936249 17550304 28004739 18362917 19820115 23185243 28797301 26830274 25576852 28049606 25765539 24845553 24508170 30249741 20566863 28327890
EMBL
EF188806
ABP01770.1
KQ459460
KPJ00803.1
KQ459838
KPJ19718.1
+ More
RSAL01000172 RVE45102.1 NWSH01000127 PCG79287.1 AGBW02014044 OWR42354.1 BABH01032652 GEHC01000716 JAV46929.1 CH477289 EAT44653.1 GGFM01003697 MBW24448.1 GGFK01007984 MBW41305.1 ADMH02001457 ETN62507.1 DS231941 EDS28079.1 GAPW01001972 JAC11626.1 APCN01003263 DQ182017 AAAB01008986 EAA00295.1 AXCM01013867 GFDL01011862 JAV23183.1 GANO01000948 JAB58923.1 GFDG01002205 JAV16594.1 CCAG010000714 CVRI01000035 CRK92729.1 JXJN01002477 GALA01001089 JAA93763.1 UFQT01000094 SSX19637.1 GAMC01001944 GAMC01001943 JAC04613.1 EF188807 ABP01771.1 GBXI01006766 GBXI01006029 JAD07526.1 JAD08263.1 GFDF01006493 JAV07591.1 CH963850 EDW74770.1 CP012524 ALC42628.1 GDHF01030676 GDHF01027518 GDHF01021188 GDHF01018398 GDHF01010919 GDHF01010352 JAI21638.1 JAI24796.1 JAI31126.1 JAI33916.1 JAI41395.1 JAI41962.1 GAKP01002195 GAKP01002194 GAKP01002193 GAKP01002192 GAKP01002191 JAC56758.1 KZ150043 PZC74536.1 CH479181 EDW31531.1 CH933808 EDW09806.1 KRG04907.1 CH940648 EDW61166.1 KRF79830.1 CM000071 EAL24812.1 M23233 M33998 M33997 AE013599 AY058572 AHN56593.1 CM002911 KMY96178.1 KMY96179.1 CH954179 KQS63084.1 KQS63086.1 CM000158 KRK00515.1 KRK00516.1 CH902619 EDV36264.1 CH916367 EDW01911.1 GEZM01010549 GEZM01010548 JAV93999.1 GEDC01024361 GEDC01014831 JAS12937.1 JAS22467.1 KQ971351 EFA06420.1 EDW92430.1 CH480824 EDW57045.1 CM000362 EDX08467.1 KMY96177.1 EDV56901.1 KQS63085.1 KRT01586.1 KRT01587.1 KPU76103.1 KPU76104.1 GFPF01008226 MAA19372.1 GEDV01004988 JAP83569.1 GEBQ01029059 JAT10918.1 GACK01002187 JAA62847.1 KQ759870 OAD62403.1 GEFH01004472 JAP64109.1 KZ288269 PBC29885.1 GECU01025091 JAS82615.1 KQ434864 KZC09104.1 GANP01000899 JAB83569.1 ABJB010060355 ABJB010102119 ABJB010154221 ABJB010160689 ABJB010358359 ABJB010951610 ABJB011011254 DS788896 EEC10034.1 GECZ01014679 JAS55090.1 KK852854 KDR14965.1 KK107419 QOIP01000003 EZA51118.1 RLU24292.1 GEFM01005987 JAP69809.1 GGMS01004148 MBY73351.1 KQ414613 KOC69060.1 GFXV01002616 MBW14421.1 ABLF02041145 GGMR01001174 MBY13793.1 DS235858 EEB19096.1 GBYB01006619 JAG76386.1 GDIP01026710 JAM77005.1 MNPL01016469 OQR70721.1 GFWV01013279 MAA38008.1
RSAL01000172 RVE45102.1 NWSH01000127 PCG79287.1 AGBW02014044 OWR42354.1 BABH01032652 GEHC01000716 JAV46929.1 CH477289 EAT44653.1 GGFM01003697 MBW24448.1 GGFK01007984 MBW41305.1 ADMH02001457 ETN62507.1 DS231941 EDS28079.1 GAPW01001972 JAC11626.1 APCN01003263 DQ182017 AAAB01008986 EAA00295.1 AXCM01013867 GFDL01011862 JAV23183.1 GANO01000948 JAB58923.1 GFDG01002205 JAV16594.1 CCAG010000714 CVRI01000035 CRK92729.1 JXJN01002477 GALA01001089 JAA93763.1 UFQT01000094 SSX19637.1 GAMC01001944 GAMC01001943 JAC04613.1 EF188807 ABP01771.1 GBXI01006766 GBXI01006029 JAD07526.1 JAD08263.1 GFDF01006493 JAV07591.1 CH963850 EDW74770.1 CP012524 ALC42628.1 GDHF01030676 GDHF01027518 GDHF01021188 GDHF01018398 GDHF01010919 GDHF01010352 JAI21638.1 JAI24796.1 JAI31126.1 JAI33916.1 JAI41395.1 JAI41962.1 GAKP01002195 GAKP01002194 GAKP01002193 GAKP01002192 GAKP01002191 JAC56758.1 KZ150043 PZC74536.1 CH479181 EDW31531.1 CH933808 EDW09806.1 KRG04907.1 CH940648 EDW61166.1 KRF79830.1 CM000071 EAL24812.1 M23233 M33998 M33997 AE013599 AY058572 AHN56593.1 CM002911 KMY96178.1 KMY96179.1 CH954179 KQS63084.1 KQS63086.1 CM000158 KRK00515.1 KRK00516.1 CH902619 EDV36264.1 CH916367 EDW01911.1 GEZM01010549 GEZM01010548 JAV93999.1 GEDC01024361 GEDC01014831 JAS12937.1 JAS22467.1 KQ971351 EFA06420.1 EDW92430.1 CH480824 EDW57045.1 CM000362 EDX08467.1 KMY96177.1 EDV56901.1 KQS63085.1 KRT01586.1 KRT01587.1 KPU76103.1 KPU76104.1 GFPF01008226 MAA19372.1 GEDV01004988 JAP83569.1 GEBQ01029059 JAT10918.1 GACK01002187 JAA62847.1 KQ759870 OAD62403.1 GEFH01004472 JAP64109.1 KZ288269 PBC29885.1 GECU01025091 JAS82615.1 KQ434864 KZC09104.1 GANP01000899 JAB83569.1 ABJB010060355 ABJB010102119 ABJB010154221 ABJB010160689 ABJB010358359 ABJB010951610 ABJB011011254 DS788896 EEC10034.1 GECZ01014679 JAS55090.1 KK852854 KDR14965.1 KK107419 QOIP01000003 EZA51118.1 RLU24292.1 GEFM01005987 JAP69809.1 GGMS01004148 MBY73351.1 KQ414613 KOC69060.1 GFXV01002616 MBW14421.1 ABLF02041145 GGMR01001174 MBY13793.1 DS235858 EEB19096.1 GBYB01006619 JAG76386.1 GDIP01026710 JAM77005.1 MNPL01016469 OQR70721.1 GFWV01013279 MAA38008.1
Proteomes
UP000053268
UP000053240
UP000283053
UP000218220
UP000007151
UP000005204
+ More
UP000008820 UP000000673 UP000069272 UP000002320 UP000075900 UP000076408 UP000075885 UP000075840 UP000007062 UP000075883 UP000075920 UP000095301 UP000076407 UP000092444 UP000078200 UP000075880 UP000183832 UP000075881 UP000092443 UP000092460 UP000075902 UP000092445 UP000095300 UP000091820 UP000192223 UP000007798 UP000092553 UP000192221 UP000008744 UP000009192 UP000008792 UP000001819 UP000000803 UP000008711 UP000002282 UP000007801 UP000001070 UP000007266 UP000001292 UP000000304 UP000242457 UP000005203 UP000076502 UP000001555 UP000027135 UP000053097 UP000279307 UP000053825 UP000007819 UP000009046 UP000192247
UP000008820 UP000000673 UP000069272 UP000002320 UP000075900 UP000076408 UP000075885 UP000075840 UP000007062 UP000075883 UP000075920 UP000095301 UP000076407 UP000092444 UP000078200 UP000075880 UP000183832 UP000075881 UP000092443 UP000092460 UP000075902 UP000092445 UP000095300 UP000091820 UP000192223 UP000007798 UP000092553 UP000192221 UP000008744 UP000009192 UP000008792 UP000001819 UP000000803 UP000008711 UP000002282 UP000007801 UP000001070 UP000007266 UP000001292 UP000000304 UP000242457 UP000005203 UP000076502 UP000001555 UP000027135 UP000053097 UP000279307 UP000053825 UP000007819 UP000009046 UP000192247
Pfam
PF00503 G-alpha
Interpro
Gene 3D
CDD
ProteinModelPortal
A4UIH0
A0A194Q5I1
A0A0N0PEF5
A0A3S2LVU8
A0A2A4K4W8
A0A212ELI8
+ More
H9J4A5 H9J430 A0A1W7R6Z0 Q17E14 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 B0WHZ7 A0A182RSW4 A0A023ESA6 A0A182YC99 A0A182P1E8 A0A182HPK4 Q7PD79 A0A182M2F4 A0A1Q3F6P3 A0A182WD25 U5EXH7 A0A1I8MH09 A0A1L8ED71 A0A182X073 A0A1B0F9I9 A0A1A9V624 A0A182JGA6 A0A1J1I2Y7 A0A182KBH2 A0A1A9YJN9 A0A1B0ARM1 A0A182UB20 A0A1A9ZRE3 A0A1I8PIV9 T1E238 A0A1A9WAB9 A0A336LTA6 W8BZ77 A4UIH1 A0A1W4WR40 A0A0A1X9B5 A0A1L8DMF1 B4MRN1 A0A0M4E7G2 A0A0K8UX10 A0A034WSM6 A0A1W4ULJ8 A0A2W1BNU2 B4GCZ3 B4KMB8 B4LNZ7 Q292P9 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A0R1DX90 B3MCN0 B4J653 A0A1Y1N8F9 A0A1B6CHJ4 D6WRY4 B4PAA4 B4I8X0 B4QBE9 A0A1W4V0L9 B3NQ28 P20354 A0A0R3NL08 A0A0P9BX57 A0A224YZY8 A0A131YWJ3 A0A1B6KHH6 L7MG91 A0A310SVF7 A0A131XB20 A0A2A3EDR2 A0A087ZZ43 A0A1B6I6U4 A0A154PCG4 V5HXV0 B7PTW2 A0A1B6FY21 A0A067QXK2 A0A026W548 A0A131XRZ4 A0A2S2Q6Y1 A0A0L7RE20 A0A2H8TKC5 J9JJY9 A0A2S2N996 E0W0E0 A0A0C9QS92 A0A0P6ASZ2 A0A1V9XBE6 A0A293MDF1
H9J4A5 H9J430 A0A1W7R6Z0 Q17E14 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 B0WHZ7 A0A182RSW4 A0A023ESA6 A0A182YC99 A0A182P1E8 A0A182HPK4 Q7PD79 A0A182M2F4 A0A1Q3F6P3 A0A182WD25 U5EXH7 A0A1I8MH09 A0A1L8ED71 A0A182X073 A0A1B0F9I9 A0A1A9V624 A0A182JGA6 A0A1J1I2Y7 A0A182KBH2 A0A1A9YJN9 A0A1B0ARM1 A0A182UB20 A0A1A9ZRE3 A0A1I8PIV9 T1E238 A0A1A9WAB9 A0A336LTA6 W8BZ77 A4UIH1 A0A1W4WR40 A0A0A1X9B5 A0A1L8DMF1 B4MRN1 A0A0M4E7G2 A0A0K8UX10 A0A034WSM6 A0A1W4ULJ8 A0A2W1BNU2 B4GCZ3 B4KMB8 B4LNZ7 Q292P9 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A0R1DX90 B3MCN0 B4J653 A0A1Y1N8F9 A0A1B6CHJ4 D6WRY4 B4PAA4 B4I8X0 B4QBE9 A0A1W4V0L9 B3NQ28 P20354 A0A0R3NL08 A0A0P9BX57 A0A224YZY8 A0A131YWJ3 A0A1B6KHH6 L7MG91 A0A310SVF7 A0A131XB20 A0A2A3EDR2 A0A087ZZ43 A0A1B6I6U4 A0A154PCG4 V5HXV0 B7PTW2 A0A1B6FY21 A0A067QXK2 A0A026W548 A0A131XRZ4 A0A2S2Q6Y1 A0A0L7RE20 A0A2H8TKC5 J9JJY9 A0A2S2N996 E0W0E0 A0A0C9QS92 A0A0P6ASZ2 A0A1V9XBE6 A0A293MDF1
PDB
5UZ7
E-value=1.22242e-163,
Score=1479
Ontologies
GO
GO:0003924
GO:0031683
GO:0007186
GO:0005525
GO:0007165
GO:0001664
GO:0007188
GO:0007608
GO:0046872
GO:0005834
GO:0007191
GO:0007268
GO:0050916
GO:0007528
GO:0005604
GO:0007476
GO:0010353
GO:2000253
GO:0005886
GO:0007632
GO:0002165
GO:0007611
GO:0048148
GO:0004871
GO:0019001
GO:0008033
GO:0003676
GO:0016787
PANTHER
Topology
Length:
380
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.2286
Exp number, first 60 AAs:
0.00035
Total prob of N-in:
0.00410
outside
1 - 380
Population Genetic Test Statistics
Pi
226.960773
Theta
154.941142
Tajima's D
0.188428
CLR
0.399726
CSRT
0.429028548572571
Interpretation
Uncertain
